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Journal Article
Journal Article
Journal Article
BBA - Molecular Cell Research, ISSN 0167-4889, 08/2013, Volume 1833, Issue 8, pp. 1936 - 1946
The differentiation of human peripheral blood monocytes into macrophages can be reproduced ex vivo by culturing the cells in the presence of colony-stimulating... 
MiR-142-3p | Egr2 | Molecular circuitry | Monocyte–macrophage differentiation | Chronic myelomonocytic leukemia | Monocyte-macrophage differentiation | TRANSCRIPTION FACTORS | DENDRITIC CELLS | RNA | BIOCHEMISTRY & MOLECULAR BIOLOGY | ALPHA | CELL BIOLOGY | PATHWAY | ACUTE LYMPHOBLASTIC-LEUKEMIA | NF-KAPPA-B | MICRORNA EXPRESSION | T-CELLS | Monocytes - cytology | Early Growth Response Protein 2 - genetics | Humans | Leukemia, Myelomonocytic, Chronic - genetics | MicroRNAs - metabolism | Monocytes - metabolism | Antigens, CD - genetics | Leukemia, Myelomonocytic, Chronic - metabolism | Receptors, IgG - metabolism | Antigens, CD - metabolism | Cell Differentiation - genetics | Receptors, IgG - genetics | Early Growth Response Protein 1 - genetics | Macrophage Colony-Stimulating Factor - pharmacology | Leukemia, Myelomonocytic, Chronic - pathology | Monocytes - physiology | Repressor Proteins - metabolism | Macrophages - physiology | Receptors, Cell Surface - metabolism | Repressor Proteins - genetics | MicroRNAs - biosynthesis | Macrophages - cytology | Down-Regulation - drug effects | Antigens, Differentiation, Myelomonocytic - genetics | GPI-Linked Proteins - metabolism | Monocytes - drug effects | Up-Regulation - drug effects | Macrophages - metabolism | Cell Differentiation - drug effects | Antigens, Differentiation, Myelomonocytic - metabolism | K562 Cells | Cell Line, Tumor | Early Growth Response Protein 2 - metabolism | Macrophages - drug effects | MicroRNAs - genetics | Early Growth Response Protein 1 - metabolism | GPI-Linked Proteins - genetics | Receptors, Cell Surface - genetics | Nerve growth factor | MicroRNA | Macrophage colony stimulating factor | Macrophages | Protein binding
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2012, Volume 59, Issue 2, pp. 166 - 177
Objectives The purpose of this study was to examine selective macrophage differentiation occurring in areas of intraplaque hemorrhage in human atherosclerosis.... 
Cardiovascular | Internal Medicine | atherosclerosis | macrophages | ABC transporters | inflammation | hemoglobin | reactive oxygen species | ACTIVATION | CD163 | CARDIAC & CARDIOVASCULAR SYSTEMS | IRON | HAPTOGLOBIN | RESPONSES | SCAVENGER RECEPTOR | CHOLESTEROL EFFLUX | SUDDEN CORONARY DEATH | INTRAPLAQUE HEMORRHAGE | BINDING | Mannose-Binding Lectins - metabolism | Reactive Oxygen Species - metabolism | Monocytes - cytology | Humans | Neovascularization, Pathologic | Orphan Nuclear Receptors - metabolism | Antigens, CD - metabolism | Lectins, C-Type - metabolism | Liver X Receptors | Hemoglobins - physiology | ATP-Binding Cassette Transporters - metabolism | Interleukin-10 - metabolism | Cell Differentiation | Monocytes - physiology | Plaque, Atherosclerotic - pathology | Receptors, Scavenger - metabolism | Macrophages - physiology | Rabbits | Atherosclerosis - pathology | Atherosclerosis - immunology | Down-Regulation | Hemorrhage - immunology | Interleukin-4 - metabolism | Receptors, Cell Surface - metabolism | Macrophages - cytology | Plaque, Atherosclerotic - immunology | Iron - metabolism | Animals | Antigens, Differentiation, Myelomonocytic - metabolism | Haptoglobin | Low density lipoproteins | Atherosclerosis | Glycosylated hemoglobin | Fluorescence | Superoxide | Apolipoproteins | Macrophages | Mitogens | Sugars | Monosaccharides | Hemoglobin | Medical colleges | Cell differentiation | Polymerase chain reaction | Angiogenesis | Flow cytometry | Cell culture | Genotype & phenotype | Rodents | Index Medicus | Abridged Index Medicus
Journal Article
Biology of Reproduction, ISSN 0006-3363, 09/2014, Volume 91, Issue 3, pp. 78 - 78
Targeted modification of the pig genome can be challenging. Recent applications of the CRISPR/Cas9 system hold promise for improving the efficacy of genome... 
Porcine/pig | Embryo | Genetic engineering | CRISPR/Cas9 | Somatic cell nuclear transfer | Blastocyst | KNOCKOUT PIGS | embryo | CAS SYSTEM | ZINC-FINGER NUCLEASES | genetic engineering | ONE-STEP GENERATION | somatic cell nuclear transfer | porcine/pig | IN-VITRO | REPRODUCTIVE BIOLOGY | RESPIRATORY SYNDROME VIRUS | PORCINE | GENE-EXPRESSION | blastocyst | CLONING EFFICIENCY | CLONED PIGS | Embryo Culture Techniques - veterinary | Sus scrofa - physiology | Genetic Engineering - veterinary | Nuclear Transfer Techniques - veterinary | Blastocyst - physiology | Male | Green Fluorescent Proteins - genetics | Receptors, Cell Surface - antagonists & inhibitors | Antigens, CD - genetics | Antigens, CD - metabolism | Sus scrofa - genetics | Embryo Transfer - veterinary | Gene Deletion | Antigens, CD1d - genetics | Female | In Vitro Oocyte Maturation Techniques - veterinary | Transgenes | Genetic Engineering - methods | Cell Line | Green Fluorescent Proteins - metabolism | Receptors, Cell Surface - metabolism | Antigens, CD1d - chemistry | Fertilization in Vitro - veterinary | Antigens, CD1d - metabolism | Antigens, Differentiation, Myelomonocytic - genetics | Embryo, Mammalian - physiology | Animals | Oocytes - physiology | Animals, Genetically Modified - genetics | Antigens, Differentiation, Myelomonocytic - metabolism | CRISPR-Cas Systems | Genetic Engineering - adverse effects | Animals, Genetically Modified - physiology | Mutation | Receptors, Cell Surface - genetics | Index Medicus
Journal Article
Journal of Infectious Diseases, ISSN 0022-1899, 04/2015, Volume 211, Issue 8, pp. 1219 - 1228
Background. Heightened immune activation among human immunodeficiency virus (HIV)-infected persons may contribute to atherosclerosis. We assessed associations... 
atherosclerosis | human immunodeficiency virus | monocyte activation | plaque | inflammation | RHEUMATOID-ARTHRITIS | INFECTIOUS DISEASES | MULTICENTER AIDS COHORT | COMPUTED-TOMOGRAPHY ANGIOGRAPHY | SOLUBLE CD163 | MICROBIOLOGY | IMMUNOLOGY | HUMAN-IMMUNODEFICIENCY-VIRUS | PROGNOSTIC VALUE | ACTIVE ANTIRETROVIRAL THERAPY | ACUTE MYOCARDIAL-INFARCTION | CHEMOATTRACTANT PROTEIN-1 | CORONARY-ARTERY-DISEASE | Antigens, CD - immunology | Prevalence | Calcium - metabolism | Chemokine CCL2 - immunology | Coronary Stenosis - metabolism | Humans | Middle Aged | Tomography, X-Ray Computed - methods | Male | Monocytes - metabolism | Monocytes - immunology | Antigens, CD - metabolism | Lipopolysaccharide Receptors - metabolism | CD4-Positive T-Lymphocytes - immunology | HIV Infections - immunology | Coronary Angiography - methods | Chemokine CCL2 - metabolism | Antigens, Differentiation, Myelomonocytic - immunology | Biomarkers - metabolism | Atherosclerosis - immunology | Plaque, Atherosclerotic - metabolism | Risk Factors | CD4-Positive T-Lymphocytes - metabolism | Receptors, Cell Surface - metabolism | Lipopolysaccharide Receptors - immunology | Plaque, Atherosclerotic - immunology | Coronary Stenosis - immunology | Receptors, Cell Surface - immunology | Antigens, Differentiation, Myelomonocytic - metabolism | Cohort Studies | HIV Infections - metabolism | Care and treatment | Monocytes | Research | HIV infection | Risk factors | Atherosclerosis | Index Medicus | Abridged Index Medicus | Major and Brief Reports
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2011, Volume 108, Issue 17, pp. 7166 - 7171
HDL cholesterol (HDL-C) plasma levels are inversely related to cardiovascular disease risk. Previous studies have shown in animals and humans that HDL promotes... 
Thoracic aorta | Monocytes | Messenger RNA | Dendritic cells | HDL lipoproteins | Atherosclerosis | Transplantation | Macrophages | Gene expression | Cholesterols | Arginase I | Alternative activation | HEART-DISEASE | alternative activation | CORONARY ATHEROSCLEROSIS | INSULIN-RESISTANCE | MULTIDISCIPLINARY SCIENCES | arginase I | DIRECTED GENE-TRANSFER | E-DEFICIENT MICE | MACROPHAGE ACTIVATION | HIGH-DENSITY-LIPOPROTEIN | APOLIPOPROTEIN-A-I | TRANSGENIC MICE | Atherosclerosis - pathology | Cholesterol, HDL - metabolism | Atherosclerosis - genetics | Humans | Receptors, CCR7 - genetics | Monocytes - metabolism | Aorta - metabolism | Cholesterol, HDL - genetics | Antigens, CD - genetics | Antigens, Differentiation, Myelomonocytic - genetics | Atherosclerosis - metabolism | Antigens, CD - metabolism | Mice, Knockout | Animals | Receptors, CCR7 - metabolism | Antigens, Differentiation, Myelomonocytic - metabolism | Apolipoproteins E - genetics | Monocytes - pathology | Mice | Foam Cells - pathology | Foam Cells - metabolism | Aorta - transplantation | Disease Models, Animal | Development and progression | Genetic aspects | Inflammation | Health aspects | Cholesterol | Plasma | Transgenic animals | Rodents | Apolipoproteins | Cells | Index Medicus | CC chemokine receptors | Animal models | CCR7 protein | Transgenic mice | phenotypic plasticity | Regression analysis | Chemokine receptors | Aortic arch | Arteriosclerosis | Plasma levels | Cardiovascular diseases | Lipoproteins (high density) | Cell migration | Plaques | Biological Sciences
Journal Article
Obesity, ISSN 1930-7381, 03/2014, Volume 22, Issue 3, pp. 747 - 757
Journal Article