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Science, ISSN 0036-8075, 1/2012, Volume 335, Issue 6066, pp. 344 - 348
Natural killer (NK) cells are lymphocytes involved in antimicrobial and antitumoral immune responses. Using N-ethyl-N-nitrosourea mutagenesis in mice, we... 
T lymphocytes | Spleen | Receptors | Phenotypes | Reactivity | REPORTS | Infections | Mice | Natural killer cells | Genetic mutation | Tumors | IMMUNITY | MOUSE NK CELLS | RECOGNITION | MULTIDISCIPLINARY SCIENCES | IN-VIVO | INHIBITORY RECEPTORS | ABSENCE | EDUCATION | EXPRESSION | ACTIVATION RECEPTOR | SELF-TOLERANCE | Antigens, Ly - genetics | Natural Cytotoxicity Triggering Receptor 1 - physiology | Natural Cytotoxicity Triggering Receptor 1 - antagonists & inhibitors | Genetic Complementation Test | Viral Load | Natural Cytotoxicity Triggering Receptor 1 - genetics | Listeriosis - immunology | Killer Cells, Natural - immunology | Transcription, Genetic | Antigens, Ly - physiology | Natural Cytotoxicity Triggering Receptor 1 - immunology | Antibodies, Monoclonal - immunology | Adaptive Immunity | Cell Line | DNA-Binding Proteins - physiology | Transcription Factors - physiology | Down-Regulation | Mice, Inbred C57BL | Mice, Transgenic | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Herpesviridae Infections - virology | Animals | Antigens, Ly - immunology | Mutagenesis | Muromegalovirus - physiology | Antibodies, Blocking - immunology | Immunologic Memory | T-Lymphocytes - immunology | CD8-Positive T-Lymphocytes - immunology | Amino Acid Substitution | Herpesviridae Infections - immunology | Signal transduction | Cellular biology | Lymphocytes | Immune system | Natural Cytotoxicity Triggering Receptor 1 | Killer Cells, Natural | Antigens, Ly | Listeriosis | CD8-Positive T-Lymphocytes | Life Sciences | Immunology | DNA-Binding Proteins | T-Lymphocytes | Antibodies, Blocking | Muromegalovirus | Antibodies, Monoclonal | Herpesviridae Infections | Transcription Factors
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2011, Volume 108, Issue 45, pp. 18324 - 18329
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2015, Volume 10, Issue 10, p. e0140804
Growing evidences indicate that Ly-GDI, an inhibitory protein of Rho GTPases, plays an essential role in regulating actin cytoskeletal alteration which is... 
CHEMOKINE GENERATION | RESPONSES | ACTIVATION | GTPASES | MULTIDISCIPLINARY SCIENCES | IMMUNE-COMPLEX ALVEOLITIS | ACUTE LUNG INJURY | TNF-ALPHA | MODEL | GTP-BINDING PROTEINS | NF-KAPPA-B | Pulmonary Alveoli - pathology | Minor Histocompatibility Antigens | Humans | Immunoglobulin G | Mice, Inbred C57BL | Cells, Cultured | Pneumonia - pathology | Pneumonia - prevention & control | Acute Lung Injury - genetics | Male | rho Guanine Nucleotide Dissociation Inhibitor beta - physiology | Acute Lung Injury - pathology | Animals | rho Guanine Nucleotide Dissociation Inhibitor beta - genetics | Acute Lung Injury - prevention & control | HEK293 Cells | Cytoprotection - genetics | Mice | Genetic Therapy - methods | Pneumonia - genetics | Inflammation | Permeability | G proteins | Adenoviruses | Lung diseases | Guanosine | Inflammatory response | Metastasis | Macrophages | Medical schools | Interleukin 6 | Proteins | Respiratory tract | Pain | Actin | Bronchoalveolar lavage | Rodents | Penicillin | Alveoli | Alveolitis | Injuries | Deposition | Expression vectors | Antigen-antibody complexes | Pathogens | NF-κB protein | Cytokines | Pulmonary arteries | Neutrophils | Bronchus | Tumor necrosis factor-α | Medicine | Hospitals | Overexpression | Lungs | Womens health | Electrophoretic mobility | Sepsis | Cytoskeleton | Anesthesiology | Laboratory animals | Phagocytosis | Chemokines | Monocyte chemoattractant protein 1
Journal Article
Nature Immunology, ISSN 1529-2908, 08/2014, Volume 15, Issue 10, pp. 929 - 937
The paradigm that macrophages that reside in steady-state tissues are derived from embryonic precursors has never been investigated in the intestine, which... 
HOMEOSTASIS | DENDRITIC CELLS | MICROGLIA | INFLAMMATION | BONE-MARROW | TISSUE-RESIDENT MACROPHAGES | RECEPTOR | STEADY-STATE | IMMUNOLOGY | MYELOID CELLS | LIFE | Receptors, CCR2 - genetics | Intestinal Mucosa - metabolism | Cell Proliferation | Receptors, CCR2 - immunology | Monocytes - metabolism | Intestines - metabolism | Monocytes - immunology | Intestines - immunology | Parabiosis | Intestinal Mucosa - cytology | CD11b Antigen - genetics | Flow Cytometry | Time Factors | Intestinal Mucosa - immunology | Bone Marrow Transplantation | Gene Expression - immunology | Antigens, Differentiation - metabolism | Antigens, Ly - metabolism | Receptors, Chemokine - genetics | Macrophages - immunology | Animals, Newborn | CD11b Antigen - immunology | Mice, Inbred C57BL | Receptors, Chemokine - metabolism | Mice, Transgenic | Receptors, Chemokine - immunology | Reverse Transcriptase Polymerase Chain Reaction | Mice, Knockout | Cell Differentiation - immunology | Macrophages - metabolism | Models, Immunological | Receptors, CCR2 - metabolism | Animals | Antigens, Ly - immunology | Antigens, Differentiation - genetics | CD11b Antigen - metabolism | CX3C Chemokine Receptor 1 | Antigens, Differentiation - immunology | Intestines - cytology | Physiological aspects | Regulation | Immune response | Microbiota (Symbiotic organisms) | Macrophages | Properties
Journal Article
Archives of Toxicology, ISSN 0340-5761, 4/2018, Volume 92, Issue 4, pp. 1495 - 1505
Allergic contact dermatitis is a widespread health disorder and occupational skin disease. Hence, screening for contact-sensitizing chemicals is highly... 
Biomedicine, general | In vitro sensitization assay | Coculture | Biomedicine | Environmental Health | Allergic contact dermatitis | Occupational Medicine/Industrial Medicine | Lymphocytes | Pharmacology/Toxicology | ASSAY | LOOSE-FIT COCULTURE | MICE | TOXICOLOGY | GAMMA RECEPTOR | CELL-LINE | Dermatitis, Allergic Contact - immunology | Immunization | Interleukin-4 Receptor alpha Subunit - metabolism | Cytokines - metabolism | Coculture Techniques | Dendritic Cells - immunology | Humans | Keratinocytes - immunology | Receptors, Interferon - metabolism | Lymphocytes - immunology | Allergens - immunology | Keratinocytes - drug effects | Hyaluronan Receptors - metabolism | Antigens, Surface - metabolism | Biological Assay | Dendritic Cells - drug effects | Allergens - toxicity | Skin - drug effects | Skin - immunology | Skin | Cytokines | Dendritic cells | T cells | High-throughput screening | Occupational diseases | Interleukin 23 | Lymphocytes T | Activation | Assaying | Dermatitis | Resorcinol | Ethics | Phenylenediamine | Interleukin 4 | Cell activation | Toxicology | Caprylic acid | CD44 antigen | Cosmetics | Skin diseases | Local lymph node assay | Sensitizing | Salicylic acid | Dermatology | Legislation | Markers | Glycerol | Keratinocytes | T cell receptors | Coumarin | Interleukin 17 | Chemicals | Screening | Monocytes | Contact dermatitis | Acids | γ-Interferon | Interferon | Surface markers | Index Medicus
Journal Article
Nature Immunology, ISSN 1529-2908, 07/2015, Volume 16, Issue 7, pp. 718 - 728
Mouse conventional dendritic cells (cDCs) can be classified into two functionally distinct lineages: the CD8 alpha(+) (CD103(+)) cDC1 lineage, and the CD11b(+)... 
CLASSICAL DENDRITIC CELLS | HOMEOSTASIS | LYMPHOID-TISSUE | HEMATOPOIETIC STEM-CELLS | MOUSE | DYNAMICS | RECEPTOR | TRANSCRIPTION-FACTOR | IMMUNOLOGY | COMMITTED PROGENITORS | EXPRESSION | Antigens, CD - immunology | Stem Cells - immunology | Oligonucleotide Array Sequence Analysis | Dendritic Cells - immunology | Antigens, Ly - genetics | Transcriptome - immunology | Stem Cells - metabolism | Antigens, CD - metabolism | Lectins - metabolism | Flow Cytometry | Single-Cell Analysis - methods | Bone Marrow Cells - immunology | Integrin alpha Chains - immunology | Antigens, Ly - metabolism | Cell Lineage - genetics | Dendritic Cells - metabolism | Microscopy, Electron, Scanning | CD11b Antigen - immunology | Lectins - immunology | Mice, Inbred C57BL | Cells, Cultured | Receptors, Cell Surface - metabolism | Mice, Transgenic | Integrin alpha Chains - metabolism | Transcriptome - genetics | Receptors, Cell Surface - immunology | CD8 Antigens - immunology | CD8 Antigens - metabolism | Animals | Antigens, Ly - immunology | Dendritic Cells - ultrastructure | Lectins - genetics | CD11b Antigen - metabolism | Bone Marrow Cells - metabolism | Cell Lineage - immunology | Cluster Analysis | Receptors, Cell Surface - genetics | Medical research | Immune response | Dendritic cells | Cell development (Biology) | Bone marrow | Medicine, Experimental | Genetic aspects | Research | Properties
Journal Article
Journal Article