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1. Full Text The Cytokine GM-CSF Drives the Inflammatory Signature of CCR2+ Monocytes and Licenses Autoimmunity
by Croxford, Andrew L and Lanzinger, Margit and Hartmann, Felix J and Schreiner, Bettina and Mair, Florian and Pelczar, Pawel and Clausen, Björn E and Jung, Steffen and Greter, Melanie and Becher, Burkhard
Immunity (Cambridge, Mass.), ISSN 1074-7613, 09/2015, Volume 43, Issue 3, pp. 502 - 514
Life Sciences & Biomedicine | Immunology | Science & Technology | Receptors, CCR2 - genetics | Granulocyte-Macrophage Colony-Stimulating Factor - metabolism | Receptors, CCR2 - immunology | Dendritic Cells - immunology | Humans | Antigens, Ly - genetics | STAT5 Transcription Factor - immunology | Autoimmunity - genetics | Monocytes - metabolism | Monocytes - immunology | Transcriptome - immunology | Interleukin-1beta - genetics | STAT5 Transcription Factor - metabolism | Signal Transduction - immunology | Inflammation - metabolism | Flow Cytometry | Autoimmunity - immunology | Interleukin-1beta - metabolism | Myeloid Cells - immunology | Antigens, Ly - metabolism | Dendritic Cells - drug effects | Myeloid Cells - drug effects | Cytokine Receptor Common beta Subunit - metabolism | Phosphorylation - immunology | Phosphorylation - drug effects | Dendritic Cells - metabolism | Cytokine Receptor Common beta Subunit - immunology | Granulocyte-Macrophage Colony-Stimulating Factor - pharmacology | Interleukin-1beta - immunology | Mice, Transgenic | Inflammation - immunology | Signal Transduction - genetics | Transcriptome - drug effects | Transcriptome - genetics | Reverse Transcriptase Polymerase Chain Reaction | Mice, Knockout | Monocytes - drug effects | Encephalomyelitis, Autoimmune, Experimental | Receptors, CCR2 - metabolism | Animals | Granulocyte-Macrophage Colony-Stimulating Factor - immunology | Antigens, Ly - immunology | Signal Transduction - drug effects | Inflammation - genetics | Myeloid Cells - metabolism | Cytokine Receptor Common beta Subunit - genetics | Flow cytometry | Phosphorylation | Disease | Cytokines | Bone marrow | Software | Inflammation | Autoimmune diseases | Index Medicus
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2. Full Text Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice
by Bain, Calum C and Bravo-Blas, Alberto and Scott, Charlotte L and Perdiguero, Elisa Gomez and Geissmann, Frederic and Henri, Sandrine and Malissen, Bernard and Osborne, Lisa C and Artis, David and Mowat, Allan McI
Nature immunology, ISSN 1529-2908, 08/2014, Volume 15, Issue 10, pp. 929 - 937
Life Sciences & Biomedicine | Immunology | Science & Technology | Receptors, CCR2 - genetics | Intestinal Mucosa - metabolism | Cell Proliferation | Receptors, CCR2 - immunology | Monocytes - metabolism | Intestines - metabolism | Monocytes - immunology | Intestines - immunology | Parabiosis | Intestinal Mucosa - cytology | CD11b Antigen - genetics | Flow Cytometry | Time Factors | Intestinal Mucosa - immunology | Bone Marrow Transplantation | Gene Expression - immunology | Antigens, Differentiation - metabolism | Antigens, Ly - metabolism | Receptors, Chemokine - genetics | Macrophages - immunology | Animals, Newborn | CD11b Antigen - immunology | Mice, Inbred C57BL | Receptors, Chemokine - metabolism | Mice, Transgenic | Receptors, Chemokine - immunology | Reverse Transcriptase Polymerase Chain Reaction | Mice, Knockout | Cell Differentiation - immunology | Macrophages - metabolism | Models, Immunological | Receptors, CCR2 - metabolism | Animals | Antigens, Ly - immunology | Antigens, Differentiation - genetics | CD11b Antigen - metabolism | CX3C Chemokine Receptor 1 | Antigens, Differentiation - immunology | Intestines - cytology | Physiological aspects | Regulation | Immune response | Microbiota (Symbiotic organisms) | Macrophages | Properties | Index Medicus
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3. Full Text Identification of cDC1- and cDC2-committed DC progenitors reveals early lineage priming at the common DC progenitor stage in the bone marrow
by Schlitzer, Andreas and Sivakamasundari, V and Chen, Jinmiao and Sumatoh, Hermi Rizal Bin and Schreuder, Jaring and Lum, Josephine and Malleret, Benoit and Zhang, Sanqian and Larbi, Anis and Zolezzi, Francesca and Renia, Laurent and Poidinger, Michael and Naik, Shalin and Newell, Evan W and Robson, Paul and Ginhoux, Florent
Nature immunology, ISSN 1529-2908, 07/2015, Volume 16, Issue 7, pp. 718 - 728
Life Sciences & Biomedicine | Immunology | Science & Technology | Antigens, CD - immunology | Stem Cells - immunology | Oligonucleotide Array Sequence Analysis | Dendritic Cells - immunology | Antigens, Ly - genetics | Transcriptome - immunology | Stem Cells - metabolism | Antigens, CD - metabolism | Lectins - metabolism | Flow Cytometry | Single-Cell Analysis - methods | Bone Marrow Cells - immunology | Integrin alpha Chains - immunology | Antigens, Ly - metabolism | Cell Lineage - genetics | Dendritic Cells - metabolism | Microscopy, Electron, Scanning | CD11b Antigen - immunology | Lectins - immunology | Mice, Inbred C57BL | Cells, Cultured | Receptors, Cell Surface - metabolism | Mice, Transgenic | Integrin alpha Chains - metabolism | Transcriptome - genetics | Receptors, Cell Surface - immunology | CD8 Antigens - immunology | CD8 Antigens - metabolism | Animals | Antigens, Ly - immunology | Dendritic Cells - ultrastructure | Lectins - genetics | CD11b Antigen - metabolism | Bone Marrow Cells - metabolism | Cell Lineage - immunology | Cluster Analysis | Receptors, Cell Surface - genetics | Medical research | Immune response | Dendritic cells | Cell development (Biology) | Bone marrow | Medicine, Experimental | Genetic aspects | Research | Properties | Index Medicus
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4. Full Text Conventional and Monocyte-Derived CD11b+ Dendritic Cells Initiate and Maintain T Helper 2 Cell-Mediated Immunity to House Dust Mite Allergen
by Plantinga, Maud and Guilliams, Martin and Vanheerswynghels, Manon and Deswarte, Kim and Branco-Madeira, Filipe and Toussaint, Wendy and Vanhoutte, Leen and Neyt, Katrijn and Killeen, Nigel and Malissen, Bernard and Hammad, Hamida and Lambrecht, Bart N
Immunity (Cambridge, Mass.), ISSN 1074-7613, 02/2013, Volume 38, Issue 2, pp. 322 - 335
Life Sciences & Biomedicine | Immunology | Science & Technology | Inflammation - pathology | Cell Proliferation | Lymph Nodes - pathology | Dendritic Cells - immunology | Antigens, Ly - genetics | Monocytes - immunology | Th2 Cells - immunology | Adoptive Transfer | Antigens, Dermatophagoides - immunology | CD11b Antigen - genetics | Receptors, IgG - genetics | Monocytes - transplantation | Allergens - immunology | Natural Cytotoxicity Triggering Receptor 1 - genetics | Antigens, Dermatophagoides - administration & dosage | Asthma - immunology | Natural Cytotoxicity Triggering Receptor 1 - immunology | Allergens - isolation & purification | Gene Expression | Lung - pathology | CD11b Antigen - immunology | Administration, Inhalation | Mice, Transgenic | Inflammation - immunology | Lymph Nodes - immunology | Receptors, IgG - immunology | Organ Specificity | Animals | Antigens, Ly - immunology | Antigens, Dermatophagoides - isolation & purification | Mice | Asthma - pathology | Dendritic Cells - transplantation | Immunity, Cellular | Lung - immunology | Cell Movement | Pyroglyphidae - immunology | Bone marrow | Cell growth | Transgenic animals | Allergies | Chemokines | Immune system | Index Medicus
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5. Full Text Recruitment of Beneficial M2 Macrophages to Injured Spinal Cord Is Orchestrated by Remote Brain Choroid Plexus
by Shechter, Ravid and Miller, Omer and Yovel, Gili and Rosenzweig, Neta and London, Anat and Ruckh, Julia and Kim, Ki-Wook and Klein, Eugenia and Kalchenko, Vyacheslav and Bendel, Peter and Lira, Sergio A and Jung, Steffen and Schwartz, Michal
Immunity (Cambridge, Mass.), ISSN 1074-7613, 03/2013, Volume 38, Issue 3, pp. 555 - 569
Life Sciences & Biomedicine | Immunology | Science & Technology | 5'-Nucleotidase - antagonists & inhibitors | 5'-Nucleotidase - genetics | Leukocyte Common Antigens - metabolism | Meninges - immunology | Spinal Cord - metabolism | Choroid Plexus - metabolism | Choroid Plexus - immunology | Monocytes - metabolism | Green Fluorescent Proteins - genetics | Monocytes - immunology | Spinal Cord Injuries - genetics | Cell Movement - genetics | Meninges - metabolism | Cell Movement - immunology | Leukocyte Common Antigens - immunology | Flow Cytometry | 5'-Nucleotidase - immunology | Gene Expression - immunology | Antigens, Ly - metabolism | Vascular Cell Adhesion Molecule-1 - genetics | Receptors, Chemokine - genetics | Macrophages - immunology | Green Fluorescent Proteins - metabolism | Vascular Cell Adhesion Molecule-1 - immunology | Blood-Brain Barrier - immunology | Mice, Inbred C57BL | Enzyme Inhibitors - pharmacology | Integrin alpha4beta1 - genetics | Receptors, Chemokine - immunology | Reverse Transcriptase Polymerase Chain Reaction | Adenosine Diphosphate - pharmacology | Blood-Brain Barrier - metabolism | Mice, Knockout | Integrin alpha4beta1 - immunology | Monocytes - drug effects | Spinal Cord - immunology | Microscopy, Confocal | Macrophages - metabolism | Animals | Antigens, Ly - immunology | Macrophages - drug effects | Spinal Cord Injuries - immunology | Mice | Adenosine Diphosphate - analogs & derivatives | CX3C Chemokine Receptor 1 | Spinal Cord Injuries - cerebrospinal fluid | Macrophages | Enzymes | Spinal cord injuries | Statistical analysis | Cytokines | Rodents | Recruitment | Index Medicus
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6. Full Text Innate production of T(H)2 cytokines by adipose tissue-associated c-Kit(+)Sca-1(+) lymphoid cells
by Moro, Kazuyo and Yamada, Taketo and Tanabe, Masanobu and Takeuchi, Tsutomu and Ikawa, Tomokatsu and Kawamoto, Hiroshi and Furusawa, Jun-ichi and Ohtani, Masashi and Fujii, Hideki and Koyasu, Shigeo
Nature (London), ISSN 0028-0836, 01/2010, Volume 463, Issue 7280, pp. 540 - U160
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | B-Lymphocytes - cytology | Cell Proliferation | Membrane Proteins - genetics | Humans | Mice, Inbred C57BL | Antigens, Ly - genetics | Gene Expression Regulation | Adipose Tissue - cytology | Membrane Proteins - immunology | Th2 Cells - immunology | Adipose Tissue - immunology | Proto-Oncogene Proteins c-kit - immunology | Nematoda - physiology | Animals | B-Lymphocytes - immunology | Lymphocytes - immunology | Antigens, Ly - immunology | Mesentery - immunology | Antigens, Ly - metabolism | Proto-Oncogene Proteins c-kit - genetics | Mice | Nematode Infections - immunology | Cytokines - immunology | Index Medicus
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7. Full Text Distinct Commensals Induce Interleukin-1β via NLRP3 Inflammasome in Inflammatory Monocytes to Promote Intestinal Inflammation in Response to Injury
by Seo, Sang-Uk and Kamada, Nobuhiko and Muñoz-Planillo, Raúl and Kim, Yun-Gi and Kim, Donghyun and Koizumi, Yukiko and Hasegawa, Mizuho and Himpsl, Stephanie D and Browne, Hilary P and Lawley, Trevor D and Mobley, Harry L.T and Inohara, Naohiro and Núñez, Gabriel
Immunity (Cambridge, Mass.), ISSN 1074-7613, 04/2015, Volume 42, Issue 4, pp. 744 - 755
Life Sciences & Biomedicine | Immunology | Science & Technology | Receptors, CCR2 - genetics | Inflammation - pathology | Hemolysin Proteins - immunology | NLR Family, Pyrin Domain-Containing 3 Protein | Proteus Infections - genetics | Receptors, CCR2 - immunology | Hemolysin Proteins - genetics | Salmonella Infections - genetics | Antigens, Ly - genetics | Salmonella Infections - immunology | Symbiosis - immunology | Monocytes - immunology | Interleukin-1beta - genetics | Intestines - immunology | Proteus Infections - pathology | Monocytes - pathology | Carrier Proteins - immunology | Macrophages - immunology | Macrophages - microbiology | Proteus mirabilis - immunology | Monocytes - microbiology | Salmonella Infections - pathology | Inflammation - microbiology | Microbiota - immunology | Macrophages - pathology | Proteus Infections - microbiology | Signal Transduction | Mice, Inbred C57BL | Gene Expression Regulation | Intestines - injuries | Interleukin-1beta - immunology | Inflammation - immunology | Proteus Infections - immunology | Inflammasomes - genetics | Mice, Knockout | Carrier Proteins - genetics | Salmonella - immunology | Animals | Intestines - microbiology | Antigens, Ly - immunology | Inflammasomes - immunology | Inflammation - genetics | Salmonella Infections - microbiology | Mice | Index Medicus
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8. Full Text Inflammatory Monocytes Activate Memory CD8+ T and Innate NK Lymphocytes Independent of Cognate Antigen during Microbial Pathogen Invasion
by Soudja, Saïdi M'Homa and Ruiz, Anne L and Marie, Julien C and Lauvau, Grégoire
Immunity (Cambridge, Mass.), ISSN 1074-7613, 09/2012, Volume 37, Issue 3, pp. 549 - 562
Life Sciences & Biomedicine | Immunology | Science & Technology | Receptors, CCR2 - genetics | Plasmodium berghei - immunology | Interleukin-18 - immunology | Receptors, CCR2 - immunology | Male | Monocytes - metabolism | Monocytes - immunology | Listeria monocytogenes - immunology | Interleukin-15 - immunology | Streptococcus pneumoniae - immunology | Flow Cytometry | Bacterial Infections - immunology | CD8-Positive T-Lymphocytes - metabolism | Killer Cells, Natural - immunology | Antigens, Ly - metabolism | Female | Bacterial Infections - microbiology | Immunologic Memory - immunology | Malaria - immunology | Mice, Inbred C57BL | Mice, Transgenic | Inflammation - immunology | Mice, Knockout | Receptors, CCR2 - metabolism | Animals | Interleukin-15 - genetics | Antigens, Ly - immunology | Interleukin-15 - metabolism | Malaria - parasitology | Antigens - immunology | Mice | Mice, Inbred BALB C | Killer Cells, Natural - metabolism | CD8-Positive T-Lymphocytes - immunology | Interleukin-18 - metabolism | Studies | Design | Medical research | Cell growth | Cytokines | T cell receptors | Infections | Experiments | Immune system | Index Medicus
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