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Journal of Hazardous Materials, ISSN 0304-3894, 12/2013, Volume 263, pp. 187 - 196
Journal Article
Regulatory Toxicology and Pharmacology, ISSN 0273-2300, 12/2016, Volume 82, pp. 20 - 31
Poor aqueous solubility and unfavourable de-esterification of olmesartan medoxomil (a selective angiotensin II receptor blocker), results in low oral... 
Olmesartan nanoemulsion | Brain penetration | Tissue distribution | Sub-chronic toxicity | Hematological parameters | Histopathological characteristics | MEDICINE, LEGAL | RATS | FORMULATION | HYPERTENSIVE PATIENTS | BIOAVAILABILITY | STROKE | PHARMACOKINETICS | DISEASE | PHARMACOLOGY & PHARMACY | TOXICOLOGY | ABSORPTION | ORGAN WEIGHT | BRAIN | Emulsions | Olmesartan Medoxomil - pharmacokinetics | Rats, Wistar | Antihypertensive Agents - administration & dosage | Body Weight - drug effects | Male | Angiotensin II Type 1 Receptor Blockers - pharmacokinetics | Olmesartan Medoxomil - chemistry | Drug Carriers | Brain - metabolism | Nanoparticles | Tissue Distribution | Tandem Mass Spectrometry | Antihypertensive Agents - toxicity | Olmesartan Medoxomil - toxicity | Water - chemistry | Chromatography, Liquid | Drug Compounding | Oils - chemistry | Angiotensin II Type 1 Receptor Blockers - administration & dosage | Olmesartan Medoxomil - administration & dosage | Reproducibility of Results | Angiotensin II Type 1 Receptor Blockers - chemistry | Risk Assessment | Administration, Oral | Toxicity Tests, Subchronic | Antihypertensive Agents - pharmacokinetics | Biomarkers - blood | Permeability | Antihypertensive Agents - chemistry | Eating - drug effects | Organ Size - drug effects | Animals | Nanomedicine - methods | Drinking - drug effects | Angiotensin II Type 1 Receptor Blockers - toxicity | Stroke (Disease) | Medical colleges | Safety and security measures | Air bases | Pharmacy | Angiotensin | Drugstores | Comparative analysis | Index Medicus
Journal Article
Journal Article
Journal Article
Journal of Pharmaceutical Sciences, ISSN 0022-3549, 11/2014, Volume 103, Issue 11, pp. 3743 - 3753
This study investigates the respirability and efficacy of peptide–micelle hybrid nanoparticles as carriers for inhalational therapy of pulmonary arterial... 
toxicity | micelle | encapsulation | controlled release | pulmonary delivery/absorption | in vitro models | nanotechnology | formulation | targeted drug delivery | phospholipids | models | in vitro | Encapsulation | Targeted drug delivery | Toxicity | Formulation | Pulmonary delivery/absorption | Micelle | Phospholipids | Controlled release | Nanotechnology | In vitro models | CHEMISTRY, MEDICINAL | absorption | DRUG-DELIVERY | RHO-KINASE INHIBITOR | CHEMISTRY, MULTIDISCIPLINARY | PACLITAXEL | NANOPARTICLES | pulmonary delivery | PHOSPHOLIPID NANOMICELLES | PHARMACOKINETICS | FORMULATIONS | PHARMACOLOGY & PHARMACY | LIPOSOMES | DERIVATIVES | NEBULIZATION | Ethanolamines - toxicity | Injections, Intravenous | Monocrotaline | 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine - analogs & derivatives | Antihypertensive Agents - administration & dosage | Hypertension, Pulmonary - physiopathology | Male | Polyethylene Glycols - chemistry | 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine - chemistry | Hypertension, Pulmonary - chemically induced | Drug Carriers | Antihypertensive Agents - toxicity | Pulmonary Artery - metabolism | Arterioles - physiopathology | Micelles | Arterial Pressure - drug effects | 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine - pharmacokinetics | Hypertension, Pulmonary - drug therapy | Oligopeptides - chemistry | Cell-Penetrating Peptides - chemistry | Disease Models, Animal | Magnetic Resonance Spectroscopy | Solubility | 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine - toxicity | Administration, Inhalation | Technology, Pharmaceutical - methods | Hypertension, Pulmonary - metabolism | Pulmonary Artery - physiopathology | Antihypertensive Agents - pharmacokinetics | Oligopeptides - metabolism | Oligopeptides - toxicity | Polyethylene Glycols - toxicity | Pulmonary Artery - drug effects | Ethanolamines - chemistry | 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine - administration & dosage | Arterioles - drug effects | Rats, Sprague-Dawley | Chemistry, Pharmaceutical | Cell-Penetrating Peptides - toxicity | Particle Size | Antihypertensive Agents - chemistry | Animals | Arterioles - metabolism | Oligopeptides - administration & dosage | Cell-Penetrating Peptides - administration & dosage | Delayed-Action Preparations | Cell-Penetrating Peptides - metabolism | Drugs | Lipids | Drug delivery systems | Peptides | Pulmonary hypertension | Vehicles | Index Medicus
Journal Article
Journal of Ethnopharmacology, ISSN 0378-8741, 01/2018, Volume 211, pp. 47 - 57
Journal Article
Journal Article
Journal Article