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1. Full Text Pharmacokinetics and exposure–effect relationships of capecitabine in elderly patients with breast or colorectal cancer
by Daher Abdi, Z and Lavau-Denes, S and Prémaud, A and Urien, S and Sauvage, F L and Martin, J and Leobon, S and Marquet, P and Tubiana-Mathieu, N and Rousseau, A
Cancer chemotherapy and pharmacology, ISSN 0344-5704, 6/2014, Volume 73, Issue 6, pp. 1285 - 1293
Response | Medicine & Public Health | Capecitabine | Oncology | Cancer Research | Pharmacology/Toxicology | Pharmacokinetics | Elderly | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Science & Technology | Gastroenterology. Liver. Pancreas. Abdomen | Stomach. Duodenum. Small intestine. Colon. Rectum. Anus | Gynecology. Andrology. Obstetrics | Mammary gland diseases | Pharmacology. Drug treatments | Biological and medical sciences | Multiple tumors. Solid tumors. Tumors in childhood (general aspects) | Medical sciences | Antineoplastic agents | Tumors | Age Factors | Antimetabolites, Antineoplastic - pharmacokinetics | Humans | Antineoplastic Combined Chemotherapy Protocols - pharmacokinetics | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | Antimetabolites, Antineoplastic - administration & dosage | Breast Neoplasms - metabolism | Deoxycytidine - pharmacokinetics | Fluorouracil - administration & dosage | Fluorouracil - adverse effects | Colorectal Neoplasms - drug therapy | Aged, 80 and over | Deoxycytidine - adverse effects | Female | Colorectal Neoplasms - metabolism | Fluorouracil - analogs & derivatives | Deoxycytidine - administration & dosage | Breast Neoplasms - drug therapy | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Breast Neoplasms - pathology | Antimetabolites, Antineoplastic - adverse effects | Aged | Colorectal Neoplasms - pathology | Fluorouracil - pharmacokinetics | Deoxycytidine - analogs & derivatives | Antimitotic agents | Cancer patients | Chemotherapy | Metabolites | Analysis | Colorectal cancer | Aged patients | Breast cancer | Cancer | Index Medicus | elderly | Antineoplastic Combined Chemotherapy Protocols | Breast Neoplasms | capecitabine | Deoxycytidine | response | pharmacokinetics | Antimetabolites, Antineoplastic | Colorectal Neoplasms | Fluorouracil
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2. Full Text Pharmacology of Anticancer Drugs in the Elderly Population
by Wildiers H and Highley M.S and de Bruijn E.A and van Oosterom A.T
2003, Volume 42, Issue 14, 30
Melphalan, pharmacokinetics | Vinblastine, pharmacokinetics | Cytarabine, pharmacokinetics | Antimetabolites, pharmacokinetics | Gemcitabine, pharmacodynamics | Vinca alkaloids, pharmacodynamics | Fluorouracil, pharmacokinetics | Ifosfamide, pharmacodynamics | Methotrexate, pharmacokinetics | Topotecan, pharmacodynamics | Capecitabine, pharmacodynamics | Irinotecan, pharmacokinetics | Vinca alkaloids, pharmacokinetics | Alkylating agents, pharmacokinetics | Chlorambucil, pharmacokinetics | Cyclophosphamide, pharmacodynamics | Vincristine, pharmacokinetics | Carboplatin, pharmacodynamics | Fludarabine, pharmacodynamics | Cisplatin, pharmacokinetics | Vinorelbine, pharmacodynamics | Capecitabine, pharmacokinetics | Platinum complexes, pharmacokinetics | Topotecan, pharmacokinetics | Cytarabine, pharmacodynamics | DNA topoisomerase inhibitors, pharmacodynamics | Chlorambucil, pharmacodynamics | Fluorouracil, pharmacodynamics | Fludarabine, pharmacokinetics | Cyclophosphamide, pharmacokinetics | Antimetabolites, pharmacodynamics | Gemcitabine, pharmacokinetics | Melphalan, pharmacodynamics | Oxaliplatin, pharmacokinetics | Vinblastine, pharmacodynamics | Vinorelbine, pharmacokinetics | Cisplatin, pharmacodynamics | Vincristine, pharmacodynamics | Oxaliplatin, pharmacodynamics | Irinotecan, pharmacodynamics | Ifosfamide, pharmacokinetics | Methotrexate, pharmacodynamics | Alkylating agents, pharmacodynamics | Platinum complexes, pharmacodynamics | Carboplatin, pharmacokinetics | Elderly | DNA topoisomerase inhibitors, pharmacokinetics | Cancer | Pharmacotherapy | Internal Medicine | Medicine & Public Health | Pharmacology/Toxicology | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Biological and medical sciences | Chemotherapy | Medical sciences | Antineoplastic agents | Pharmacology. Drug treatments | Drug Interactions | Antineoplastic Agents - adverse effects | Humans | Aged, 80 and over | Aging | Aged | Antineoplastic Agents - pharmacokinetics | Antineoplastic Agents - pharmacology | Frail Elderly | Patient Compliance | Neoplasms - drug therapy | Randomized Controlled Trials as Topic | Index Medicus
Book Review
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3. Full Text Germline Genetic Variation in an Organic Anion Transporter Polypeptide Associated With Methotrexate Pharmacokinetics and Clinical Effects
by Lisa R. Treviño and Noriko Shimasaki and Wenjian Yang and John C. Panetta and Cheng Cheng and Deqing Pei and Diana Chan and Alex Sparreboom and Kathleen M. Giacomini and Ching-Hon Pui and William E. Evans and Mary V. Relling
Journal of clinical oncology, ISSN 0732-183X, 12/2009, Volume 27, Issue 35, pp. 5972 - 5978
Life Sciences & Biomedicine | Oncology | Science & Technology | Prospective Studies | Antimetabolites, Antineoplastic - pharmacokinetics | Humans | Methotrexate - pharmacokinetics | Child, Preschool | Infant | Male | Organic Anion Transporters - metabolism | Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Precursor Cell Lymphoblastic Leukemia-Lymphoma - metabolism | Organic Anion Transporters - genetics | Antimetabolites, Antineoplastic - blood | Germ-Line Mutation | Female | Child | Genetic Predisposition to Disease | Genome-Wide Association Study | Risk Assessment | Risk Factors | Linear Models | Logistic Models | Treatment Outcome | Methotrexate - blood | Linkage Disequilibrium | Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics | Methotrexate - adverse effects | Phenotype | Gastrointestinal Diseases - genetics | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Adolescent | Antimetabolites, Antineoplastic - adverse effects | Polymorphism, Single Nucleotide | Solute Carrier Organic Anion Transporter Family Member 1b1 | Gastrointestinal Diseases - chemically induced | Index Medicus | Original Reports | Pedi2
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4. Full Text Pharmacokinetics of different formulations of oral azacitidine (CC‐486) and the effect of food and modified gastric pH on pharmacokinetics in subjects with hematologic malignancies
by Laille, Eric and Savona, Michael R and Scott, Bart L and Boyd, Thomas E and Dong, Qian and Skikne, Barry
Journal of clinical pharmacology, ISSN 0091-2700, 06/2014, Volume 54, Issue 6, pp. 630 - 639
pharmacokinetics | formulation | CC‐486 | effect of food | oral azacitidine | proton‐pump inhibitor | CC-486 | proton-pump inhibitor | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Stomach - chemistry | Azacitidine - pharmacokinetics | Antimetabolites, Antineoplastic - pharmacokinetics | Tablets | Administration, Oral | Food-Drug Interactions | Humans | Middle Aged | Azacitidine - chemistry | Male | Antimetabolites, Antineoplastic - chemistry | Chemistry, Pharmaceutical | Antimetabolites, Antineoplastic - administration & dosage | Antimetabolites, Antineoplastic - blood | Capsules | Delayed-Action Preparations - pharmacokinetics | Aged, 80 and over | Female | Aged | Azacitidine - blood | Hematologic Neoplasms - metabolism | Azacitidine - administration & dosage | Hydrogen-Ion Concentration | Influence | Care and treatment | Pharmacokinetics | Blood diseases | Hydrogen-ion concentration | Analysis | Index Medicus
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5. Full Text Clinical Pharmacokinetics of Capecitabine
by Reigner B and Blesch K and Weidekamm E
2001, Volume 40, Issue 2, 20
Capecitabine, pharmacokinetics | Paclitaxel, drug interactions | Antineoplastics, pharmacokinetics | Capecitabine, drug interactions | Docetaxel, drug interactions | Warfarin, drug interactions | Drug food interactions | Drug interactions | Antacids, drug interactions | Folinic acid, drug interactions | Pharmacotherapy | Internal Medicine | Medicine & Public Health | Pharmacology/Toxicology | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Biological and medical sciences | Chemotherapy | Medical sciences | Antineoplastic agents | Pharmacology. Drug treatments | Paclitaxel - metabolism | Leucovorin - metabolism | Antimetabolites, Antineoplastic - pharmacokinetics | Fluorouracil - analogs & derivatives | Capecitabine | Humans | Paclitaxel - analogs & derivatives | Intestinal Absorption | Dose-Response Relationship, Drug | Antacids - metabolism | Antimetabolites, Antineoplastic - therapeutic use | Deoxycytidine - pharmacokinetics | Deoxycytidine - therapeutic use | Deoxycytidine - metabolism | Drug Interactions | Taxoids | Colorectal Neoplasms - drug therapy | Protein Binding | Liver Diseases - metabolism | Antimetabolites, Antineoplastic - metabolism | Deoxycytidine - analogs & derivatives | Food | Index Medicus
Book Review
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6. Full Text Phase III, Randomized Study of Gemcitabine and Oxaliplatin Versus Gemcitabine (fixed-dose rate infusion) Compared With Gemcitabine (30-minute infusion) in Patients With Pancreatic Carcinoma E6201: A Trial of the Eastern Cooperative Oncology Group
by Elizabeth Poplin and Yang Feng and Jordan Berlin and Mace L. Rothenberg and Howard Hochster and Edith Mitchell and Steven Alberts and Peter O'Dwyer and Daniel Haller and Paul Catalano and David Cella and Al Bowen Benson III
Journal of clinical oncology, ISSN 0732-183X, 08/2009, Volume 27, Issue 23, pp. 3778 - 3785
Life Sciences & Biomedicine | Oncology | Science & Technology | Gastroenterology. Liver. Pancreas. Abdomen | Biological and medical sciences | Medical sciences | Liver. Biliary tract. Portal circulation. Exocrine pancreas | Tumors | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Antimetabolites, Antineoplastic - pharmacokinetics | United States | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - pharmacokinetics | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | Antimetabolites, Antineoplastic - administration & dosage | Pancreatic Neoplasms - drug therapy | Deoxycytidine - pharmacokinetics | Organoplatinum Compounds - administration & dosage | Adult | Deoxycytidine - adverse effects | Female | Drug Administration Schedule | Deoxycytidine - administration & dosage | Kaplan-Meier Estimate | Treatment Outcome | Infusions, Intravenous - methods | Disease-Free Survival | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Antimetabolites, Antineoplastic - adverse effects | Aged | Deoxycytidine - analogs & derivatives | Index Medicus | Original Reports | Gic26
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7. Full Text Development of Both Methotrexate and Mitomycin C Loaded PEGylated Chitosan Nanoparticles for Targeted Drug Codelivery and Synergistic Anticancer Effect
by Jia, Mengmeng and Li, Yang and Yang, Xiangrui and Huang, Yuancan and Wu, Hongjie and Huang, Yu and Lin, Jinyan and Li, Yanxiu and Hou, Zhenqing and Zhang, Qiqing
ACS applied materials & interfaces, ISSN 1944-8244, 07/2014, Volume 6, Issue 14, pp. 11413 - 11423
methotrexate | mitomycin C | drug delivery | PEGylated chitosan | receptor-mediated targeting | Science & Technology - Other Topics | Materials Science | Nanoscience & Nanotechnology | Technology | Materials Science, Multidisciplinary | Science & Technology | Methotrexate - pharmacology | Mitomycin - chemistry | Antibiotics, Antineoplastic - pharmacology | Antimetabolites, Antineoplastic - pharmacokinetics | Nanoparticles - chemistry | Humans | Methotrexate - pharmacokinetics | Polyethylene Glycols - chemistry | Antibiotics, Antineoplastic - chemistry | Chitosan - pharmacology | Antimetabolites, Antineoplastic - pharmacology | Antibiotics, Antineoplastic - pharmacokinetics | Methotrexate - chemistry | Polyethylene Glycols - pharmacology | Polyethylene Glycols - pharmacokinetics | Antimetabolites, Antineoplastic - chemistry | Mitomycin - pharmacology | Drug Synergism | Animals | Chitosan - chemistry | Chitosan - pharmacokinetics | Mice | Mitomycin - pharmacokinetics | HeLa Cells | Drug Delivery Systems - methods | Neoplasms, Experimental - drug therapy | Index Medicus
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8. Full Text Pharmacokinetics and pharmacogenetics of Gemcitabine as a mainstay in adult and pediatric oncology: an EORTC-PAMM perspective
by Ciccolini, Joseph and Serdjebi, Cindy and Peters, Godefridus J and Giovannetti, Elisa
Cancer chemotherapy and pharmacology, ISSN 0344-5704, 07/2016, Volume 78, Issue 1, pp. 1 - 12
Gemcitabine prodrugs | Pharmacogenetics | Gemcitabine | 2 ',2 '-difluoro-2 '-deoxyuridine | Polymorphisms | Cytidine deaminase | Medicine & Public Health | Oncology | Cancer Research | Pharmacology/Toxicology | 2′,2′-difluoro-2′-deoxyuridine | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Science & Technology | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Antimetabolites, Antineoplastic - pharmacokinetics | Deoxycytidine - administration & dosage | Humans | Antineoplastic Combined Chemotherapy Protocols - pharmacokinetics | Antimetabolites, Antineoplastic - administration & dosage | Neoplasms - drug therapy | Polymorphism, Genetic | Deoxycytidine - pharmacokinetics | Animals | Neoplasms - genetics | Adult | Neoplasms - pathology | Child | Deoxycytidine - analogs & derivatives | Precision Medicine - methods | Enzymes | Liver | Lung cancer | Nucleosides | Physiological aspects | DNA synthesis | Rankings | Nucleotides | Genetic polymorphisms | Index Medicus | Review
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