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Accounts of chemical research, ISSN 0001-4842, 2017, Volume 50, Issue 10, pp. 2510 - 2518
.... In this Account, we detail our findings in the area of novel metal-based antibiotics. Our strategy is based on the modification of simple antimicrobial peptides (AMPs... 
Laboratorium voor Organische chemie | Laboratory for Organic Chemistry | Organische Chemie | Organic Chemistry | COLISTIN | ANTIMICROBIAL PEPTIDES | CHEMISTRY, MULTIDISCIPLINARY | PSEUDOMONAS-AERUGINOSA | METALLOCENES | COMPLEXES
Journal Article
PloS one, ISSN 1932-6203, 10/2015, Volume 10, Issue 10, p. e0140377
Journal Article
Nucleic acid therapeutics, ISSN 2159-3337, 10/2012, Volume 22, Issue 5, pp. 323 - 334
Journal Article
Journal Article
Bioconjugate chemistry, ISSN 1043-1802, 08/2012, Volume 23, Issue 8, pp. 1639 - 1647
Journal Article
Current topics in medicinal chemistry, ISSN 1568-0266, 2018, Volume 18, Issue 22, pp. 1926 - 1936
The menace of multi-drug resistance by bacterial pathogens that are responsible for infectious diseases in humans and animals cannot be over-emphasized. Many... 
Covalent conjugation | Antibiotic-peptide conjugate | Antibiotics | AMR | DNA | Antimicrobial peptide | CHEMISTRY, MEDICINAL | HELIX | ANTIMICROBIAL PEPTIDES | DAPTOMYCIN | Pathogens | Efflux | Conjugates | Stability | Peptides | Toxicity | Multidrug resistance | Cytotoxicity | Drug resistance | Proteins | Infectious diseases | Bacteria | Conjugation | Mutation | Physicochemical properties | Binding sites | Deoxyribonucleic acid--DNA
Journal Article
Antimicrobial agents and chemotherapy, ISSN 1098-6596, 2017, Volume 61, Issue 4
.... Here, we tested peptide-conjugated phosphorodiamidate morpholino oligomers (PPMOs), which inhibit translation of complementary mRNA from specific, essential genes... 
Experimental therapeutics | Antibiotic resistance | PPMO | Antimicrobial agents | Antisense | Pseudomonas aeruginosa | Phosphorodiamidate morpholino oligomer | OUTER-MEMBRANE | INHALED TOBRAMYCIN | ESCHERICHIA-COLI | ANTIBIOTIC-RESISTANCE | MICROBIOLOGY | DYSTROPHIN EXPRESSION | antimicrobial agents | experimental therapeutics | antibiotic resistance | phosphorodiamidate morpholino oligomer | CYSTIC-FIBROSIS PATIENTS | IN-VIVO | VESTIBULAR TOXICITY | PHARMACOLOGY & PHARMACY | AMINO-ACID-COMPOSITION | ANTISENSE OLIGONUCLEOTIDES | antisense | Fatty Acid Synthase, Type II - antagonists & inhibitors | Fatty Acid Synthase, Type II - genetics | Humans | Pseudomonas aeruginosa - growth & development | Biofilms - growth & development | Fatty Acid Synthase, Type II - metabolism | Molecular Targeted Therapy | Ribosomal Proteins - metabolism | Microbial Sensitivity Tests | Pseudomonas aeruginosa - metabolism | Anti-Bacterial Agents - chemistry | Female | Amidohydrolases - metabolism | Biofilms - drug effects | Ribosomal Proteins - antagonists & inhibitors | Oligonucleotides, Antisense - pharmacology | Peptides - chemistry | Pseudomonas Infections - drug therapy | Ribosomal Proteins - genetics | Amidohydrolases - genetics | Oligonucleotides, Antisense - chemistry | Amidohydrolases - antagonists & inhibitors | Pseudomonas aeruginosa - drug effects | Pseudomonas Infections - microbiology | Morpholinos - chemistry | Peptides - pharmacology | Animals | Pseudomonas aeruginosa - genetics | Morpholinos - pharmacology | Anti-Bacterial Agents - pharmacology | Mice | Mice, Inbred BALB C | Gene Expression Regulation, Bacterial
Journal Article