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Mini-Reviews in Medicinal Chemistry, ISSN 1389-5575, 2013, Volume 13, Issue 2, pp. 163 - 193
Objective: Piper has been used for long timelike condiment and food, but also in traditional medicine around of the world. This work resumes the available and... 
Pharmacological actions | Piperaceae | Complementary medicine | Phytochemical constituents | Piper | OXIDATIVE STRESS | CHEMISTRY, MEDICINAL | LIPID-PEROXIDATION | ALZHEIMERS-DISEASE | LARVICIDAL ACTIVITY | LUNG CARCINOGENESIS | ORAL SUPPLEMENTATION | B16F-10 MELANOMA-CELLS | IN-VITRO | pharmacological actions | complementary medicine | HEALTHY-VOLUNTEERS | phytochemical constituents | CYTOTOXIC PYRIDONE ALKALOIDS | Anti-Infective Agents - toxicity | Central Nervous System Agents - therapeutic use | Plant Extracts - chemistry | Plant Extracts - toxicity | Antioxidants - chemistry | Obesity - drug therapy | Plant Extracts - pharmacology | Anti-Infective Agents - pharmacology | Cardiovascular Diseases - drug therapy | Humans | Platelet Aggregation Inhibitors - toxicity | Anti-Obesity Agents - therapeutic use | Anti-Obesity Agents - toxicity | Anti-Infective Agents - chemistry | Anti-Inflammatory Agents - therapeutic use | Platelet Aggregation Inhibitors - pharmacology | Antineoplastic Agents, Phytogenic - therapeutic use | Platelet Aggregation Inhibitors - therapeutic use | Alkaloids - toxicity | Alkaloids - pharmacology | Central Nervous System Agents - chemistry | Anti-Inflammatory Agents - pharmacology | Anti-Inflammatory Agents - toxicity | Anti-Infective Agents - therapeutic use | Antineoplastic Agents, Phytogenic - chemistry | Cardiovascular Agents - toxicity | Antioxidants - pharmacology | Cognition Disorders - drug therapy | Piper - chemistry | Cardiovascular Agents - pharmacology | Neoplasms - drug therapy | Antineoplastic Agents, Phytogenic - toxicity | Antioxidants - toxicity | Cardiovascular Agents - therapeutic use | Anti-Obesity Agents - chemistry | Antioxidants - therapeutic use | Animals | Anti-Inflammatory Agents - chemistry | Central Nervous System Agents - pharmacology | Platelet Aggregation Inhibitors - chemistry | Alkaloids - therapeutic use | Antineoplastic Agents, Phytogenic - pharmacology | Anti-Obesity Agents - pharmacology | Plant Extracts - therapeutic use | Alkaloids - chemistry | Central Nervous System Agents - toxicity | Cardiovascular Agents - chemistry
Journal Article
Clinical journal of the American Society of Nephrology, ISSN 1555-905X, 2012, Volume 7, Issue 10, pp. 1713 - 1721
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2010, Volume 330, Issue 6005, pp. 831 - 835
.... Finally, oral administration of an inhibitor protected mice fromCPT-11-induced toxicity... 
Enzymes | Anaerobic bacteria | Toxicity | REPORTS | Colorectal cancer | Diarrhea | Anaerobic conditions | Bacteria | Mice | Monomers | Crystal structure | IRINOTECAN CPT-11 | DIARRHEA | METABOLISM | COLITIS | MULTIDISCIPLINARY SCIENCES | BETA-GLUCURONIDASE | CAMPTOTHECINS | TOPOISOMERASE-I | PHARMACOGENETICS | GUT FLORA | CARCINOMA | Camptothecin - toxicity | Humans | Colon - drug effects | Glucuronidase - metabolism | Crystallography, X-Ray | Diarrhea - prevention & control | Intestinal Mucosa - drug effects | Prodrugs - metabolism | Enzyme Inhibitors - chemistry | Female | Glucuronidase - antagonists & inhibitors | Antineoplastic Agents, Phytogenic - metabolism | Escherichia coli Proteins - antagonists & inhibitors | Bacteria, Anaerobic - drug effects | Drug Evaluation, Preclinical | Camptothecin - analogs & derivatives | Camptothecin - metabolism | Escherichia coli - enzymology | Enzyme Inhibitors - metabolism | Colon - pathology | Glucuronidase - isolation & purification | Enzyme Inhibitors - pharmacology | Models, Molecular | Escherichia coli Proteins - metabolism | Glucuronidase - chemistry | Intestinal Mucosa - microbiology | Escherichia coli Proteins - isolation & purification | Antineoplastic Agents, Phytogenic - toxicity | Animals | Prodrugs - toxicity | Cell Line, Tumor | Protein Conformation | Colon - microbiology | Mice, Inbred BALB C | Glucuronidase - pharmacology | Escherichia coli Proteins - chemistry | Intestinal Mucosa - pathology | Antimitotic agents | Drugs | Prevention | Complications and side effects | Care and treatment | Dosage and administration | Antineoplastic agents | Health aspects | Cancer | Chemotherapy | Side effects | Index Medicus | Microorganisms | Inhibitors | LARGE INTESTINE | BACTERIA | NEOPLASMS | BASIC BIOLOGICAL SCIENCES | CRYSTAL STRUCTURE | TOXICITY | 60 APPLIED LIFE SCIENCES | ENZYMES | ORAL ADMINISTRATION | TARGETS | MICE | SIDE EFFECTS
Journal Article
Journal Article
European Journal of Heart Failure, ISSN 1388-9842, 01/2017, Volume 19, Issue 1, pp. 9 - 42
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Circulation (New York, N.Y.), ISSN 0009-7322, 2013, Volume 128, Issue 17, pp. 1927 - 1995
Journal Article