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Toxicology, ISSN 0300-483X, 2006, Volume 217, Issue 2, pp. 213 - 220
Caffeic acid (3,4-dihydroxycinnamic acid) is among the major hydroxycinnamic acids present in wine; sinapic acid, which is a potent antioxidant. It has also... 
Reducing power | Metal chelating | 3,4-Dihydroxycinnamic acid | Antioxidant activity | Caffeic acid | Radical scavenging | OXIDATION | HYDROXYCINNAMIC ACIDS | PHENOLIC-COMPOUNDS | L | antioxidant activity | metal chelating | OXYGEN | radical scavenging | IN-VITRO | PLANTS | PHARMACOLOGY & PHARMACY | TOXICOLOGY | caffeic acid | reducing power | EXTRACTS | DERIVATIVES | 3,4-dihydroxycinnamic acid | Free Radical Scavengers - pharmacology | Emulsions | Linoleic Acid - metabolism | Caffeic Acids - pharmacology | Dose-Response Relationship, Drug | Butylated Hydroxyanisole - pharmacology | Biphenyl Compounds - pharmacology | Chromans - pharmacology | Ferrous Compounds - pharmacology | Lipid Peroxidation - drug effects | Superoxides - metabolism | Thiocyanates - pharmacology | Picrates | Superoxides - antagonists & inhibitors | Ferricyanides - metabolism | Iron - pharmacology | alpha-Tocopherol - pharmacology | Hydrazines - pharmacology | Caffeic Acids - chemistry | Antioxidants - pharmacology | Chelating Agents - pharmacology | Sulfonic Acids - pharmacology | Reducing Agents - pharmacology | Butylated Hydroxytoluene - pharmacology | Ferrous Compounds - metabolism | Benzothiazoles | Unsaturated fatty acids | Iron compounds | Potassium compounds | Toluene | Butylated hydroxyanisole | Superoxide | Essential fatty acids | Index Medicus
Journal Article
Circulation Research: Journal of the American Heart Association, ISSN 0009-7330, 08/2003, Volume 93, Issue 4, pp. 311 - 320
ABSTRACT—Homocysteine (Hcy) is an independent risk factor for cardiovascular disease. Monocyte chemoattractant protein-1 (MCP-1) and interleukin-8 (IL-8) are... 
Monocyte chemoattractant protein-1 | Monocytes | Homocysteine | Interleukin-8 | Atherosclerosis | homocysteine | atherosclerosis | monocytes | ENDOTHELIAL-CELL INJURY | OXIDATIVE STRESS | CARDIAC & CARDIOVASCULAR SYSTEMS | OXIDANT STRESS | monocyte chemoattractant protein-1 | RISK FACTOR | PLASMA HOMOCYST(E)INE | interleukin-8 | VASCULAR-DISEASE | PERIPHERAL VASCULAR DISEASE | SMOOTH-MUSCLE-CELLS | ATHEROMATOUS PLAQUES | HEMATOLOGY | NF-KAPPA-B | T-LYMPHOCYTES | Interleukin-8 - genetics | Reactive Oxygen Species - metabolism | Chemokine CCL2 - secretion | Monocytes - cytology | Humans | Dimethyl Sulfoxide - pharmacology | Monocytes - metabolism | RNA, Messenger - metabolism | Pyrrolidines - pharmacology | Dose-Response Relationship, Drug | Thiocarbamates - pharmacology | Chromans - pharmacology | Time Factors | Homocysteine - pharmacology | Indoles - pharmacology | Interleukin-8 - secretion | Flavonoids - pharmacology | RNA, Messenger - drug effects | RNA, Messenger - genetics | Cells, Cultured | Enzyme Inhibitors - pharmacology | Chemokine CCL2 - genetics | Imidazoles - pharmacology | Tyrphostins - pharmacology | Antioxidants - pharmacology | Onium Compounds - pharmacology | Sulfonamides - pharmacology | Naphthalenes - pharmacology | Gene Expression Regulation - drug effects | Monocytes - drug effects | Genistein - pharmacology | Pyridines - pharmacology | Thiazoles - pharmacology | Thiazolidinediones | Index Medicus
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 08/2014, Volume 73, pp. 51 - 59
Microglia are the resident immune cells in the brain. Microglial activation is characteristic of several inflammatory and neurodegenerative diseases including... 
Peroxynitrite | Free radicals | Protein radical | Inducible nitric oxide synthase | Lipopolysaccharide | Nitrone adducts | Parkinson disease | Microglia | NADPH OXIDASE | OXIDATIVE STRESS | MACROPHAGES | BIOCHEMISTRY & MOLECULAR BIOLOGY | INOS EXPRESSION | KAPPA-B | LIPOPOLYSACCHARIDE-ACTIVATED MICROGLIA | REACTIVE OXYGEN | ENDOCRINOLOGY & METABOLISM | GENERATION | TYROSINE NITRATION | PARKINSONS-DISEASE | Microglia - metabolism | Metalloporphyrins - pharmacology | Lipopolysaccharides | Thiocarbamates - pharmacology | RNA Interference | Nitric Oxide Synthase Type II - antagonists & inhibitors | Spin Trapping | Acetophenones - pharmacology | Free Radicals - metabolism | Proline - pharmacology | Microglia - cytology | NG-Nitroarginine Methyl Ester - pharmacology | NF-kappa B - antagonists & inhibitors | Proline - analogs & derivatives | Enzyme Inhibitors - pharmacology | Imidazoles - pharmacology | Antioxidants - pharmacology | Neurodegenerative Diseases - metabolism | Coumarins - pharmacology | Animals | Nitric Oxide Synthase Type II - genetics | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | Peroxynitrous Acid - metabolism | Amidines - pharmacology | Mice | Pyridines - pharmacology | RNA, Small Interfering | Benzylamines - pharmacology | Cell Line, Transformed | Boronic Acids - pharmacology | Nitric Oxide Synthase Type II - metabolism | Nitration | Nervous system diseases | Multiple sclerosis | Analysis | Nitric oxide | Environmental health | Physiological aspects | Alzheimer's disease | Index Medicus | Inducible nitric | oxide synthase | LPS | Parkinson’s disease
Journal Article
International Journal of Oncology, ISSN 1019-6439, 12/2013, Volume 43, Issue 6, pp. 1787 - 1798
The highly aggressive adult sarcomas are characterized by high levels of matrix metalloproteinase (MMP)-2 and -9, which play crucial roles in tumor invasion... 
inhibitors | synovial sarcoma | inducers | chondrosarcoma | cytokines | liposarcoma | matrix metalloproteinases | fibrosarcoma | Chondrosarcoma | Inhibitors | Matrix metalloproteinases | Cytokines | Synovial sarcoma | Liposarcoma | Fibrosarcoma | Inducers | CANCER-CELLS | VITAMIN-C | TUMOR INVASION | ASCORBIC-ACID | GREEN TEA | ONCOLOGY | NUTRIENT MIXTURE | SERUM-LEVELS | SOFT-TISSUE SARCOMA | ENDOTHELIAL GROWTH-FACTOR | Interleukin-1beta - pharmacology | Tetradecanoylphorbol Acetate - pharmacology | Humans | Fibrosarcoma - metabolism | Liposarcoma - metabolism | Matrix Metalloproteinase 9 - metabolism | Carcinogens - pharmacology | Dexamethasone - pharmacology | Antineoplastic Agents - pharmacology | Catechin - pharmacology | Matrix Metalloproteinase 2 - biosynthesis | Tretinoin - pharmacology | Matrix Metalloproteinase 9 - biosynthesis | Anti-Inflammatory Agents - pharmacology | Matrix Metalloproteinase 2 - metabolism | Sarcoma, Synovial - metabolism | Antioxidants - pharmacology | Sarcoma - metabolism | Matrix Metalloproteinase Inhibitors - pharmacology | Tumor Necrosis Factor-alpha - pharmacology | Chondrosarcoma - metabolism | Lipopolysaccharides - pharmacology | Cell Line, Tumor | Doxycycline - pharmacology | Anti-Bacterial Agents - pharmacology | Catechin - analogs & derivatives | Dactinomycin - pharmacology | Studies | Tea | Cell growth | Medical prognosis | Collagen | Penicillin | Tumor necrosis factor-TNF | Physiology | Metastasis | Growth factors | Cancer
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 02/2015, Volume 479, Issue 1, pp. 88 - 95
Zinc oxide (ZnO) appears as a promising preservative for pharmaceutical or cosmetic formulations. The other ingredients of the formulations may have specific... 
Zinc oxide | Excipients | Challenge tests | Topical formulations | Interactions | Preservative | OUTER-MEMBRANE | SUSPENSIONS | EFFICACY | PARTICLES | COMPLEX-FORMATION | BACTERICIDAL ACTIVITY | ANTIBACTERIAL ACTIVITY | BUTYLATED HYDROXYTOLUENE | PSEUDOMONAS-AERUGINOSA | PHARMACOLOGY & PHARMACY | ZNO | Titanium - pharmacology | Antioxidants - chemistry | Magnesium Sulfate - pharmacology | Sodium Chloride - pharmacology | Anti-Infective Agents - pharmacology | Escherichia coli - drug effects | Pseudomonas aeruginosa - growth & development | Titanium - chemistry | Butylated Hydroxytoluene - chemistry | Candida albicans - growth & development | Preservatives, Pharmaceutical - pharmacology | Preservatives, Pharmaceutical - chemistry | Candida albicans - drug effects | Excipients - chemistry | Zinc Oxide - chemistry | Anti-Infective Agents - chemistry | Edetic Acid - pharmacology | Ascorbic Acid - chemistry | Escherichia coli - growth & development | Sodium Chloride - chemistry | Ascorbic Acid - analogs & derivatives | Chelating Agents - chemistry | Aspergillus - growth & development | Zinc Oxide - pharmacology | Antioxidants - pharmacology | Chelating Agents - pharmacology | Pseudomonas aeruginosa - drug effects | Aspergillus - drug effects | Magnesium Sulfate - chemistry | Edetic Acid - chemistry | Ascorbic Acid - pharmacology | Butylated Hydroxytoluene - pharmacology | Excipients - pharmacology | Staphylococcus aureus - drug effects | Staphylococcus aureus - growth & development | Administration, Topical | Index Medicus | Life Sciences | Engineering Sciences | Chemical and Process Engineering | Pharmaceutical sciences
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 12/2005, Volume 280, Issue 52, pp. 42655 - 42668
How genetic and environmental factors interact in Parkinson disease is poorly understood. We have now compared the patterns of vulnerability and rescue of... 
OXIDATIVE DAMAGE | COMPLEX-I | MEMBRANE PERTURBATION | UBIQUITIN-PROTEIN LIGASE | DROSOPHILA MODEL | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE MODEL | C-ELEGANS | DEFICIENT MICE | HUNTINGTONS-DISEASE | TAUROURSODEOXYCHOLIC ACID | Oncogene Proteins - genetics | Cholagogues and Choleretics - pharmacology | Humans | Molecular Sequence Data | Immunoblotting | Pyridazines - pharmacology | Probucol - pharmacology | Taurochenodeoxycholic Acid - pharmacology | Copper - chemistry | Time Factors | Gene Deletion | Rotenone - pharmacology | Neurons - metabolism | alpha-Synuclein - genetics | Paraquat - pharmacology | Transgenes | Disease Models, Animal | Pyrazoles - pharmacology | Amino Acid Sequence | Parkinson Disease - pathology | Caenorhabditis elegans - metabolism | Electron Transport Complex I - antagonists & inhibitors | Gene Library | Animals, Genetically Modified | Iron - chemistry | Polyenes - pharmacology | Gene Expression Regulation | Oxygen Consumption | Intracellular Signaling Peptides and Proteins | Bile Acids and Salts - metabolism | Ions | Mitochondria - metabolism | Antioxidants - pharmacology | Genetic Techniques | Sequence Homology, Amino Acid | Protein Deglycase DJ-1 | Animals | Mutagenesis | Benzoates - pharmacology | Thiazoles - pharmacology | Mutation | 3-Hydroxybutyric Acid - pharmacology | Ubiquitin-Protein Ligases - genetics | Sodium Azide - pharmacology | Apoptosis | RNA, Small Interfering - metabolism | Index Medicus
Journal Article
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 01/2000, Volume 28, Issue 1, pp. 55 - 63
Reactive oxygen species have been shown to be involved in the mutagenicity, clastogenicity, and apoptosis of mammalian cells treated with arsenic or cadmium.... 
Excision repair | Reactive oxygen species | Peroxynitrite | Hydrogen peroxide | Free radicals | Nitric oxide | nitric oxide | free radicals | OXIDATIVE STRESS | peroxynitrite | NITRIC-OXIDE SYNTHASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | hydrogen peroxide | SODIUM ARSENITE | STRAND BREAKS | excision repair | CHINESE-HAMSTER CELLS | reactive oxygen species | HEAT-SHOCK RESPONSE | L-ARGININE | ENDOCRINOLOGY & METABOLISM | HYDROGEN-PEROXIDE | WELL WATER | MALIGNANT NEOPLASMS | Cadmium Chloride - toxicity | Catalase - pharmacology | Free Radical Scavengers - pharmacology | Amitrole - pharmacology | Mutagens - toxicity | Citrulline - analogs & derivatives | Reactive Oxygen Species - metabolism | Nitric Oxide Synthase - antagonists & inhibitors | Endothelium, Vascular - drug effects | Molsidomine - analogs & derivatives | Thiourea - pharmacology | Endothelium, Vascular - chemistry | Phenanthrolines - pharmacology | Chromans - pharmacology | Arsenites - toxicity | Cattle | Superoxides - metabolism | Nitric Oxide Donors - pharmacology | Superoxide Dismutase - pharmacology | N-Glycosyl Hydrolases - pharmacology | Cells, Cultured | Enzyme Inhibitors - pharmacology | Sodium Selenite - pharmacology | Antioxidants - pharmacology | Onium Compounds - pharmacology | Hydrogen Peroxide - metabolism | Nitroarginine - pharmacology | Nitrates - metabolism | Bacterial Proteins - pharmacology | DNA-Formamidopyrimidine Glycosylase | Animals | Citrulline - pharmacology | Ditiocarb - pharmacology | Escherichia coli Proteins | Sodium Compounds - toxicity | Uric Acid - pharmacology | Molsidomine - pharmacology | Thiomalates - pharmacology | Aorta - cytology | DNA Damage | Nitric Oxide - metabolism | Thiourea - analogs & derivatives | formamidopyrimidine-DNA glycosylase | formamidopyrimidine | 3-morpholinosydnonimine | 8-oxoguanine | Index Medicus
Journal Article
Journal of Food Science, ISSN 0022-1147, 08/2016, Volume 81, Issue 8, pp. H2049 - H2058
Contents of total flavonoids, total phenolics, total triterpenes, total condensed tannin and total saponins in peels, flesh and endocarps of Chaenomeles... 
digestion | antioxidant | endocarp | α‐glucosidase inhibitory | Chaenomeles | in vitro | α-glucosidase inhibitory | in vitro digestion | ANTIOXIDANT ACTIVITY | APOPTOSIS | TRITERPENOIDS | FOOD SCIENCE & TECHNOLOGY | PYRUS SPP | OLEANOLIC ACID | alpha-glucosidase inhibitory | POLYPHENOLS | IN-VITRO DIGESTION | MICE | EXTRACTS | TUMOR-GROWTH | Plant Extracts - chemistry | Flavonoids - analysis | Gallic Acid - pharmacology | Triterpenes - pharmacology | Species Specificity | Plant Extracts - pharmacology | Rutin - pharmacology | Oleanolic Acid - pharmacology | Glycoside Hydrolase Inhibitors - analysis | Chromatography, High Pressure Liquid | Biphenyl Compounds - metabolism | Vanillic Acid - pharmacology | Catechin - analysis | Proanthocyanidins - pharmacology | China | Gallic Acid - analysis | Proanthocyanidins - analysis | Flavonoids - pharmacology | Vanillic Acid - analysis | Catechin - pharmacology | Antioxidants - analysis | Phenols - pharmacology | Coumaric Acids - analysis | Fruit - chemistry | Picrates - metabolism | Rutin - analysis | Saponins - analysis | Antioxidants - pharmacology | Glycoside Hydrolase Inhibitors - pharmacology | Oleanolic Acid - analysis | Rosaceae - chemistry | Triterpenes - analysis | Phenols - analysis | Propionates | alpha-Glucosidases - metabolism | Coumaric Acids - pharmacology | Saponins - pharmacology | Composition | Methods | Rosaceae | Food | Testing | Phenols | Flavonoids | Food science | Fruits | Triterpenes | Saponins | Catechin | Gallic acid | Principal components analysis | Mass spectroscopy | Chlorogenic acid | Glucosidase | Colorimetry | Liquid chromatography | Rutin | High-performance liquid chromatography | Epicatechin | Oleanolic acid | Antioxidants | Acids | Correlation analysis | Vanillic acid | Ursolic acid | Mass spectrometry | High performance liquid chromatography | Index Medicus | Catechins | Tannins | Condensing | Digestion
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 04/2001, Volume 276, Issue 17, pp. 13750 - 13755
Journal Article