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European Journal of Medicinal Chemistry, ISSN 0223-5234, 05/2017, Volume 131, pp. 237 - 254
A new series of –substituted 2–pyrazolines , , , and were obtained from the cyclocondensation reaction of [(7–chloroquinolin–4–yl)amino]chalcones with... 
Antifungal activity | Chalcones | Antimalarial activity | Antitrypanosomal activity | 2–pyrazolines | Anticancer activity | Quinoline | Antibacterial activity | Antileishmanial activity | ANTIPLASMODIAL ACTIVITY | CHEMISTRY, MEDICINAL | HYBRID MOLECULES | INHIBITORY PROPERTIES | CELL-GROWTH | 2-pyrazolines | IN-VITRO | CHALCONE DERIVATIVES | PLASMODIUM-FALCIPARUM | ANTILEISHMANIAL AGENTS | ANTIMICROBIAL ACTIVITY | Parasitic Sensitivity Tests | Pyrazoles - chemical synthesis | Antineoplastic Agents - chemical synthesis | Humans | Bacteria - drug effects | Antifungal Agents - chemical synthesis | Antifungal Agents - chemistry | Structure-Activity Relationship | Plasmodium falciparum - drug effects | Quinolines - pharmacology | Dose-Response Relationship, Drug | Microbial Sensitivity Tests | Pyrazoles - chemistry | Anti-Bacterial Agents - chemistry | Antiprotozoal Agents - chemical synthesis | Antineoplastic Agents - pharmacology | Molecular Structure | Pyrazoles - pharmacology | Antifungal Agents - pharmacology | Cell Survival - drug effects | Fungi - drug effects | Quinolines - chemistry | Antiprotozoal Agents - chemistry | Antineoplastic Agents - chemistry | Antiprotozoal Agents - pharmacology | Anti-Bacterial Agents - chemical synthesis | Cell Line, Tumor | Anti-Bacterial Agents - pharmacology | Cell Proliferation - drug effects | Drug Screening Assays, Antitumor | Care and treatment | Malaria | Antifungal agents | Drug resistance | Antibacterial agents | Cancer | Index Medicus
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 09/2014, Volume 84, pp. 343 - 363
Fourteen new organotin(IV) complexes with general formula R SnL or R SnL where R = CH , C H , C H , C H , C H , CH –C H , C(CH ) , C H and... 
Organotin(IV) compound | Antitumor activity | Cytotoxicity | Antimicrobial activity | DNA interaction | Antileishmanial activity | CHEMISTRY, MEDICINAL | ACID | MOLECULAR-STRUCTURE | ANTITUMOR-ACTIVITY | DISK DIFFUSION | NMR | SPECTROSCOPIC CHARACTERIZATION | X-RAY STRUCTURES | BIOLOGICAL SCREENINGS | DERIVATIVES | CALF THYMUS DNA | Organotin Compounds - chemistry | Parasitic Sensitivity Tests | Humans | Bacteria - drug effects | Crystallography, X-Ray | Antifungal Agents - chemical synthesis | Antifungal Agents - chemistry | Structure-Activity Relationship | Dose-Response Relationship, Drug | Microbial Sensitivity Tests | Organotin Compounds - chemical synthesis | Anti-Bacterial Agents - chemistry | Leishmania - drug effects | Antiprotozoal Agents - chemical synthesis | Molecular Structure | Antifungal Agents - pharmacology | Fungi - drug effects | Organotin Compounds - pharmacology | Models, Molecular | Antiprotozoal Agents - chemistry | Antiprotozoal Agents - pharmacology | Solanum tuberosum - microbiology | DNA, Single-Stranded - chemistry | Solanum tuberosum - drug effects | Anti-Bacterial Agents - chemical synthesis | Artemia - drug effects | Animals | DNA, Single-Stranded - drug effects | Plasmids | Ligands | Anti-Bacterial Agents - pharmacology | Plant Tumors - microbiology | Tin compounds | Amphotericin B | Analysis | Spectrum analysis | DNA | Genetic research | Antiparasitic agents | Chemical properties | Mass spectrometry
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 09/2017, Volume 138, pp. 774 - 806
Journal Article
Journal Article
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 06/2017, Volume 25, Issue 11, pp. 2817 - 2824
Journal Article
Journal Article
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 01/2018, Volume 143, pp. 1903 - 1918
Fourteen new organotin(IV) carboxylate complexes with peptide linkage of (2-(4-methoxy-2-nitrophenylcarbamoyl)benzoic acid) were successfully synthesized and... 
Structural elucidation | Antibacterial activity | Peptide linkage organotin(IV) derivative | DNA interaction study | Antileishmanial activity | Anticancer activity | CHEMISTRY, MEDICINAL | COMPLEXES | ACID-DERIVATIVES | NMR | ANTICANCER | MOLECULAR-STRUCTURES | SPECTROSCOPIC CHARACTERIZATION | X-RAY STRUCTURES | BIOLOGICAL SCREENINGS | CATALYTIC-ACTIVITY | CALF THYMUS DNA | Organotin Compounds - chemistry | Parasitic Sensitivity Tests | Antineoplastic Agents - chemical synthesis | Humans | Bacteria - drug effects | Structure-Activity Relationship | Dose-Response Relationship, Drug | Microbial Sensitivity Tests | Peptides - metabolism | Anti-Bacterial Agents - chemistry | Carboxylic Acids - chemistry | Drug Design | Antiprotozoal Agents - chemical synthesis | Antineoplastic Agents - pharmacology | Molecular Structure | Carboxylic Acids - pharmacology | Organotin Compounds - pharmacology | Peptides - chemistry | Leishmania major - drug effects | Cells, Cultured | Antiprotozoal Agents - chemistry | Antineoplastic Agents - chemistry | Antiprotozoal Agents - pharmacology | Anti-Bacterial Agents - chemical synthesis | Anti-Bacterial Agents - pharmacology | Cell Proliferation - drug effects | Drug Screening Assays, Antitumor | Benzoic acid | Tin compounds | Peptides | Lung cancer | Analysis | Antibacterial agents | Investigations | Organic acids
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 01/2018, Volume 143, pp. 97 - 106
A series of N-benzyl tetrahydropiperidinylidene pyrrolidinium salts have been synthesized and investigated for their antiplasmodial and antitrypanosomal... 
Antimicrobial | Benzyl tetrahydropiperidinylidene ammonium salts | Anticancer | Antiprotozoal | ammonium salts | DRUG-SENSITIVITY | CHEMISTRY, MEDICINAL | TRYPANOSOMA-BRUCEI | ASSAY | Benzyl tetrahydropiperidinylidene | INVITRO | RHODESIENSE | Parasitic Sensitivity Tests | Pyridines - chemistry | Antineoplastic Agents - chemical synthesis | Humans | Bacteria - drug effects | Saccharomyces cerevisiae - drug effects | Antifungal Agents - chemical synthesis | Antifungal Agents - chemistry | Structure-Activity Relationship | Plasmodium falciparum - drug effects | Quaternary Ammonium Compounds - chemistry | Benzyl Compounds - chemistry | Dose-Response Relationship, Drug | Microbial Sensitivity Tests | Salts - chemistry | Salts - pharmacology | Anti-Bacterial Agents - chemistry | Salts - chemical synthesis | Antiprotozoal Agents - chemical synthesis | Antineoplastic Agents - pharmacology | Molecular Structure | Antifungal Agents - pharmacology | Pyridines - chemical synthesis | Rats | Antiprotozoal Agents - chemistry | Antineoplastic Agents - chemistry | Antiprotozoal Agents - pharmacology | Anti-Bacterial Agents - chemical synthesis | Animals | Benzyl Compounds - pharmacology | Cell Line, Tumor | Anti-Bacterial Agents - pharmacology | Cell Proliferation - drug effects | Mice | Pyridines - pharmacology | Trypanosoma brucei rhodesiense - drug effects | Benzyl Compounds - chemical synthesis | Quaternary Ammonium Compounds - chemical synthesis | Drug Screening Assays, Antitumor | Quaternary Ammonium Compounds - pharmacology | Ammonium compounds | Plasmodium falciparum | Hydroxides | Malaria | Ammonium paratungstate | Aluminum compounds | Esters | Carbonates | Antibacterial agents
Journal Article