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Marine drugs, ISSN 1660-3397, 2013, Volume 11, Issue 7, pp. 2510 - 2573
The peer-reviewed marine pharmacology literature from 2009 to 2011 is presented in this review, following the format used in the 1998-2008 reviews of this... 
Drug | Toxicology | Chemical | Marine | Metabolite | Product | Pharmacology | Pharmaceutical | Review | Natural | toxicology | product | pharmaceutical | CHEMISTRY, MEDICINAL | natural | NATURAL-PRODUCTS | SOFT CORAL | OCTOCORAL SARCOPHYTON-EHRENBERGI | CORAL LOBOPHYTUM-DURUM | ALGA CALLOPHYCUS-SERRATUS | ANTIMICROBIAL PEPTIDES | marine | drug | SPONGE CYMBASTELA-HOOPERI | metabolite | chemical | review | pharmacology | A-C | CYANOBACTERIUM LYNGBYA-MAJUSCULA | BROWN ALGA | Antitubercular Agents - chemistry | Humans | Antifungal Agents - chemistry | Antitubercular Agents - isolation & purification | Antiviral Agents - chemistry | Anti-Bacterial Agents - chemistry | Anti-Inflammatory Agents - isolation & purification | Aquatic Organisms - chemistry | Biological Factors - isolation & purification | Antifungal Agents - pharmacology | Antiviral Agents - pharmacology | Anti-Inflammatory Agents - pharmacology | Antitubercular Agents - pharmacology | Antiprotozoal Agents - chemistry | Hypoglycemic Agents - chemistry | Anti-Bacterial Agents - isolation & purification | Antiprotozoal Agents - pharmacology | Antiprotozoal Agents - isolation & purification | Hypoglycemic Agents - pharmacology | Antifungal Agents - isolation & purification | Hypoglycemic Agents - isolation & purification | Animals | Anti-Inflammatory Agents - chemistry | Nervous System - drug effects | Immune System - drug effects | Anti-Bacterial Agents - pharmacology | Biological Factors - chemistry | Antiviral Agents - isolation & purification | Biological Factors - pharmacology
Journal Article
Mini reviews in medicinal chemistry, ISSN 1389-5575, 05/2017, Volume 17, Issue 8, pp. 693 - 720
...: The present review aims to summarize extraction and isolation methods and biological activities of the different types of neolignans covering the period from 1968... 
Natural products | Neolignans | Piperaceae | Isolation | Extraction | Piper | Biological activity | CHEMISTRY, MEDICINAL | NATURAL-PRODUCTS | ANTIFUNGAL ACTIVITY | MACHILUS-THUNBERGII | isolation | extraction | TETRAHYDROFURAN LIGNANS | I FLOS-MAGNOLIAE | RECEPTOR ANTAGONIST | natural products | neolignans | NEGLECTED TROPICAL DISEASES | SAURURUS-CHINENSIS | PLATELET-ACTIVATING-FACTOR | DC. VAR. SOLMSIANUM | Plant Extracts - chemistry | Antioxidants - chemistry | Plant Extracts - pharmacology | Humans | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Anti-Inflammatory Agents, Non-Steroidal - isolation & purification | Lignans - pharmacology | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Neuroprotective Agents - pharmacology | Antineoplastic Agents - isolation & purification | Anti-Bacterial Agents - chemistry | Antineoplastic Agents - pharmacology | Neuroprotective Agents - chemistry | Lignans - chemistry | Plant Extracts - isolation & purification | Antiprotozoal Agents - chemistry | Anti-Bacterial Agents - isolation & purification | Antioxidants - pharmacology | Antineoplastic Agents - chemistry | Antiprotozoal Agents - pharmacology | Piper - chemistry | Antiprotozoal Agents - isolation & purification | Lignans - isolation & purification | Neuroprotective Agents - isolation & purification | Antioxidants - isolation & purification | Anti-Bacterial Agents - pharmacology
Journal Article
Current pharmaceutical biotechnology, ISSN 1389-2010, 2009, Volume 10, Issue 1, pp. 86 - 105
Journal Article
Journal of natural products (Washington, D.C.), ISSN 0163-3864, 01/2018, Volume 81, Issue 1, pp. 188 - 202
Journal Article
Mini reviews in medicinal chemistry, ISSN 1389-5575, 2018, Volume 18, Issue 13, pp. 1110 - 1132
Journal Article
Applied Microbiology and Biotechnology, ISSN 0175-7598, 2/2019, Volume 103, Issue 4, pp. 1627 - 1642
Journal Article
PloS one, ISSN 1932-6203, 2017, Volume 12, Issue 2, pp. e0171476 - e0171476
Seven metabolites were obtained from the microbial transformation of anabolic-androgenic steroid mibolerone (1) with Cunninghamella blakesleeana, C.... 
COLON-CANCER | BIOCATALYSTS | SURVIVAL | CELLS | CISPLATIN-INDUCED CYTOTOXICITY | PRODUCTS | MULTIDISCIPLINARY SCIENCES | HYDROXYLATION | ANDROGEN | MICROBIAL TRANSFORMATION | CERVICAL-CANCER | NIH 3T3 Cells | Antiprotozoal Agents - metabolism | Humans | 17-Ketosteroids - pharmacology | Chromatography, High Pressure Liquid | Carbonic Anhydrases - chemistry | Nandrolone - metabolism | Testosterone Congeners - chemistry | Antineoplastic Agents - metabolism | Testosterone Congeners - isolation & purification | 17-Ketosteroids - chemistry | Saccharomycetales - chemistry | Cunninghamella - metabolism | Antineoplastic Agents - isolation & purification | Biotransformation | Leishmania major - growth & development | Glucuronidase - antagonists & inhibitors | Antineoplastic Agents - pharmacology | Molecular Structure | Monophenol Monooxygenase - chemistry | Cell Survival - drug effects | Saccharomycetales - drug effects | 17-Ketosteroids - metabolism | Cunninghamella - drug effects | Hydroxylation | Leishmania major - drug effects | 17-Ketosteroids - isolation & purification | Nandrolone - analogs & derivatives | Antiprotozoal Agents - chemistry | Glucuronidase - chemistry | Antineoplastic Agents - chemistry | Testosterone Congeners - pharmacology | Antiprotozoal Agents - pharmacology | Cunninghamella - chemistry | Antiprotozoal Agents - isolation & purification | Animals | Nandrolone - pharmacology | Testosterone Congeners - metabolism | Mice | HeLa Cells | Saccharomycetales - metabolism | Nandrolone - chemistry | alpha-Glucosidases - chemistry | Anabolic steroids | Research | Metabolites | Transformation | Promastigotes | Toxicity | Colorectal cancer | Cytotoxicity | Biocatalysts | Cancer therapies | Tropical diseases | Microorganisms | Parasitic diseases | Cervical carcinoma | Enzymes | Glucosidase | Breast cancer | Cervix | Substrates | Biological activity | Chromatography | Chemistry | Carbonic anhydrase | Tyrosinase | Cervical cancer | Cancer | Steroids | Index Medicus
Journal Article
Phytochemistry (Oxford), ISSN 0031-9422, 2009, Volume 70, Issue 7, pp. 907 - 912
.... and Garcinia cymosa K. Schum (Clusiaceae), have resulted in the isolation of a xanthone, 1,5-dihydroxy-3,6-dimethoxy-2,7-diprenylxanthone, 1,7-dihydroxyxanthone, isoxanthochymol, β-sitosterol-3- O-β... 
Isoxanthochymol | Plasmodium falciparum | Garcinia cornea | 3β-Hydroxy-5-glutinen-28-oic acid | Garcinia celebica | Garcinia griffithii | Clusiaceae | Garcihombronane D | Garcinia cymosa | 1,5-Dihydroxy-3,6-dimethoxy-2,7-diprenylxanthone | Antiprotozoal activity | LANOSTANES | TRITERPENOIDS | 3 beta-Hydroxy-5-glutinen-28-oic acid | NATURAL-PRODUCTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | XANTHONES | CHEMOTHERAPY | LEADING COMPOUNDS | PLANT SCIENCES | FRIEDOLANOSTANES | ROOT BARK | BENZOPHENONES | ASSIGNMENTS | Triterpenes - pharmacology | Sitosterols - pharmacology | Benzophenones - pharmacology | Stigmasterol - pharmacology | Lanosterol - pharmacology | Lanosterol - analogs & derivatives | Stigmasterol - chemistry | Flavones - chemistry | Plasmodium falciparum - drug effects | Xanthones - pharmacology | Plant Bark - chemistry | Antimalarials - isolation & purification | Triterpenes - chemistry | Garcinia - chemistry | Glucosides - chemistry | Sitosterols - chemistry | Molecular Structure | Flavones - isolation & purification | Catechin - pharmacology | Stigmasterol - analogs & derivatives | Stigmasterol - isolation & purification | Benzophenones - isolation & purification | Plant Leaves - chemistry | Xanthones - chemistry | Benzophenones - chemistry | Glucosides - pharmacology | Plants, Medicinal - chemistry | Xanthones - isolation & purification | Sitosterols - isolation & purification | Antiprotozoal Agents - chemistry | Lanosterol - isolation & purification | Antiprotozoal Agents - pharmacology | Antimalarials - pharmacology | Antiprotozoal Agents - isolation & purification | Glucosides - isolation & purification | Animals | Lanosterol - chemistry | Antimalarials - chemistry | Catechin - isolation & purification | Triterpenes - isolation & purification | Catechin - chemistry | Indonesia | Saponins | Malaria | Analysis | Pharmacy | Universities and colleges | Terpenes | Isoflavones
Journal Article
Journal of natural products (Washington, D.C.), ISSN 0163-3864, 06/2003, Volume 66, Issue 6, pp. 823 - 828
Journal Article
Natural product reports, ISSN 0265-0568, 2001, Volume 18, Issue 6, pp. 674 - 688
... the most common pathogens in the world; they are recognized as the causative agents of some of the most serious tropical diseases in both man and domestic animals. Malaria... 
CHEMISTRY, MEDICINAL | VERNONIA-BRACHYCALYX | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | BALB/C MICE | CUTANEOUS LEISHMANIASIS | PEPEROMIA GALIOIDES | IN-VITRO | 2-SUBSTITUTED QUINOLINE ALKALOIDS | ANTIPROTOZOAL ACTIVITY | ANTILEISHMANIAL ACTIVITY | BISBENZYLISOQUINOLINE ALKALOIDS | IMMUNOSTIMULANT ACTIVITY | Phenols - isolation & purification | Humans | Alkaloids - isolation & purification | Quinones - isolation & purification | Biological Products - pharmacology | Saponins - chemistry | Terpenes - pharmacology | Terpenes - chemistry | Saponins - therapeutic use | Quinones - pharmacology | Biological Products - therapeutic use | Phenols - pharmacology | Plants, Medicinal - chemistry | Alkaloids - pharmacology | Quinones - chemistry | Terpenes - isolation & purification | Quinones - therapeutic use | Leishmaniasis - drug therapy | Antiprotozoal Agents - chemistry | Antiprotozoal Agents - pharmacology | Biological Products - isolation & purification | Antiprotozoal Agents - isolation & purification | Biological Products - chemistry | Saponins - isolation & purification | Phenols - therapeutic use | Terpenes - therapeutic use | Alkaloids - therapeutic use | Phenols - chemistry | Leishmaniasis - parasitology | Antiprotozoal Agents - therapeutic use | Alkaloids - chemistry | Saponins - pharmacology
Journal Article
Phytotherapy research, ISSN 0951-418X, 2010, Volume 25, Issue 3, pp. 315 - n/a
Extracts from different species of the genus Ferula (Apiaceae) have had various biomedical applications for many centuries. Many biological features of this... 
bioactive compounds | biological activity | Apiaceae | sesquiterpene coumarins | Ferula | Sesquiterpene coumarins | Bioactive compounds | Biological activity | CHEMISTRY, MEDICINAL | ACID | CANCER CHEMOPREVENTIVE ACTIVITY | SZOWITSIANA | COMMUNIS | PRENYLATED COUMARIN | UMBELLIPRENIN | ANTIBACTERIAL ACTIVITY | PHARMACOLOGY & PHARMACY | INHIBITORS | CYTOTOXICITY | CONSTITUENTS | Sesquiterpenes - isolation & purification | Antiviral Agents - pharmacology | Sesquiterpenes - chemistry | Anti-Inflammatory Agents - pharmacology | Antineoplastic Agents, Phytogenic - chemistry | Coumarins - chemistry | Antiprotozoal Agents - chemistry | Anti-Bacterial Agents - isolation & purification | ATP-Binding Cassette, Sub-Family B, Member 1 - antagonists & inhibitors | Antiprotozoal Agents - pharmacology | Antiprotozoal Agents - isolation & purification | Coumarins - pharmacology | Coumarins - isolation & purification | Anti-Inflammatory Agents - chemistry | Antiviral Agents - chemistry | Anti-Bacterial Agents - chemistry | Anti-Bacterial Agents - pharmacology | Anti-Inflammatory Agents - isolation & purification | Molecular Structure | Sesquiterpenes - pharmacology | Antineoplastic Agents, Phytogenic - pharmacology | Antiviral Agents - isolation & purification | Ferula - chemistry | Antineoplastic Agents, Phytogenic - isolation & purification
Journal Article
Molecules (Basel, Switzerland), ISSN 1420-3049, 12/2015, Volume 20, Issue 12, pp. 22157 - 22169
.... No cytotoxic effect was detected in mammalian cells (CC50 1727.48 mu g/mL or CC50 5268 mu M). Classical chromatographic techniques and spectral methods led to the isolation... 
Leishmanicidal activity | Leishmania (L.) amazonensis | Alkaloid (+)-phyllanthidine | PHYSALIS-ANGULATA | BIOCHEMISTRY & MOLECULAR BIOLOGY | TANNINS | LEAVES | DISCOIDEA | FLAVONOIDS | CHEMISTRY, MULTIDISCIPLINARY | CHEMOTHERAPY | alkaloid (+)-phyllanthidine | leishmanicidal activity | ANTILEISHMANIAL ACTIVITY | EXTRACTS | EUPHORBIACEAE | ALKALOIDS | Plant Extracts - chemistry | Alkaloids - isolation & purification | Male | Heterocyclic Compounds, 4 or More Rings - pharmacology | Dose-Response Relationship, Drug | Kaempferols - isolation & purification | Inhibitory Concentration 50 | Macrophages, Peritoneal - drug effects | Hydrolyzable Tannins - isolation & purification | Life Cycle Stages - drug effects | Gallic Acid - isolation & purification | Leishmania braziliensis - drug effects | Euphorbiaceae - chemistry | Leishmania braziliensis - growth & development | Antiprotozoal Agents - pharmacology | Antiprotozoal Agents - isolation & purification | Heterocyclic Compounds, 4 or More Rings - isolation & purification | Macrophages, Peritoneal - parasitology | Glucosides - isolation & purification | Phytochemicals - isolation & purification | Animals | Triterpenes - isolation & purification | Leishmania braziliensis - ultrastructure | Mice | Mice, Inbred BALB C | Primary Cell Culture | Phytochemicals - pharmacology | Vector-borne diseases | Promastigotes | Gallic acid | Toxicity | Identification methods | Kaempferol | Cytotoxicity | Parasites | Leishmaniasis | Macrophages | Amastigotes | Chromatography | Spectral methods | Mammalian cells | Cutaneous leishmaniasis | Alkaloids | Organic chemistry | Acids | Betulinic acid
Journal Article