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Journal Article
The World Journal of Biological Psychiatry, ISSN 1562-2975, 04/2013, Volume 14, Issue 3, pp. 154 - 219
Journal Article
JAMA Psychiatry, ISSN 2168-622X, 05/2015, Volume 72, Issue 5, pp. 438 - 445
IMPORTANCE: Antipsychotic medications are associated with increased mortality in older adults with dementia, yet their absolute effect on risk relative to no... 
MORTALITY | MEDICATIONS | METAANALYSIS | EFFICACY | PSYCHIATRY | ALZHEIMERS-DISEASE | NEUROPSYCHIATRIC SYMPTOMS | OLDER-ADULTS | DRUGS | PLACEBO-CONTROLLED TRIALS | ATYPICAL ANTIPSYCHOTICS | United States - epidemiology | Antipsychotic Agents - adverse effects | Humans | Middle Aged | Male | Risk | Case-Control Studies | Dose-Response Relationship, Drug | Psychotropic Drugs - adverse effects | Dibenzothiazepines - adverse effects | Risperidone - adverse effects | Female | Registries | Retrospective Studies | Dementia - drug therapy | Quetiapine Fumarate | Veterans - psychology | Psychotropic Drugs - administration & dosage | Haloperidol - adverse effects | Dementia - mortality | Antipsychotic Agents - administration & dosage | Aged | Benzodiazepines - adverse effects | Veterans - statistics & numerical data | Antidepressive Agents - adverse effects | Dosage and administration | Antipsychotic drugs | Mortality | Analysis | Risk factors | Dementia | Veterans | Comorbidity | Americans | Survivors | Outpatient Treatment | Longitudinal Study | Psychiatric Disorders | Epidemiology | Benzodiazepines | Conventional Antipsychotics | Anticonvulsants | Cognitive Disorders | Etiology | Psychopharmacology | Opioids | Aging | Antidepressant Drugs | Atypical Antipsychotics | PTSD (ICD-9) | Negative Therapeutic Reaction | Index Medicus | Abridged Index Medicus
Journal Article
Neuropharmacology, ISSN 0028-3908, 01/2013, Volume 64, pp. 215 - 223
Phosphodiesterase 10A (PDE10A) is a novel target for the treatment of schizophrenia that may address multiple symptomatic domains associated with this... 
Schizophrenia | Phosphodiesterase 10A | Striatum | Cognition | OBJECT RETRIEVAL | CYCLIC-NUCLEOTIDE PHOSPHODIESTERASES | IMMUNOHISTOCHEMICAL LOCALIZATION | STRIATUM-ENRICHED PHOSPHODIESTERASE | AMPA RECEPTOR | SYNAPTIC PLASTICITY | NEUROSCIENCES | PREFRONTAL CORTEX | MEMORY DYSFUNCTION | DOPAMINE-D-2 RECEPTOR OCCUPANCY | ANIMAL-MODELS | PHARMACOLOGY & PHARMACY | Pyrimidines - blood | Memory, Episodic | Male | Macaca mulatta | Cognition Disorders - prevention & control | Antipsychotic Agents - therapeutic use | Behavior, Animal - drug effects | Neurons - metabolism | Phosphorylation - drug effects | Pyridines - administration & dosage | Phosphodiesterase Inhibitors - pharmacokinetics | Rats | Random Allocation | Neurons - enzymology | Corpus Striatum - drug effects | Pyrimidines - pharmacokinetics | Phosphodiesterase Inhibitors - therapeutic use | Schizophrenia - metabolism | Rats, Wistar | Antipsychotic Agents - blood | Pyridines - pharmacokinetics | Molecular Targeted Therapy | Corpus Striatum - metabolism | Dose-Response Relationship, Drug | Protein Processing, Post-Translational - drug effects | Schizophrenia - physiopathology | Cognition Disorders - etiology | Neurons - drug effects | Corpus Striatum - enzymology | Pyridines - therapeutic use | Nerve Tissue Proteins - antagonists & inhibitors | Phosphoric Diester Hydrolases - metabolism | Schizophrenia - blood | Pyrimidines - administration & dosage | Nootropic Agents - pharmacokinetics | Nootropic Agents - therapeutic use | Antipsychotic Agents - pharmacokinetics | Nootropic Agents - blood | Phosphodiesterase Inhibitors - blood | Phosphoric Diester Hydrolases - chemistry | Antipsychotic Agents - administration & dosage | Nerve Tissue Proteins - metabolism | Phosphodiesterase Inhibitors - administration & dosage | Pyridines - blood | Animals | Nootropic Agents - administration & dosage | Pyrimidines - therapeutic use | Schizophrenia - drug therapy | Executive Function - drug effects | Enzymes | Plasma physics | Protein binding | Index Medicus
Journal Article
BMJ, ISSN 0959-8138, 2/2012, Volume 344, Issue 7848, pp. 16 - 16
Objective To assess risks of mortality associated with use of individual antipsychotic drugs in elderly residents in nursing homes.Design Population based... 
RESEARCH | Nursing homes | Mortality | Cohort studies | Antipsychotic agents | Medicaid | Older adults | Research universities | Population aging | Universities | Dementia | MORTALITY | MEDICINE, GENERAL & INTERNAL | DEMENTIA | EFFICACY | ALZHEIMERS-DISEASE | BEHAVIORAL SYMPTOMS | ELDERLY USERS | ADULTS | ADJUSTMENT | ATYPICAL ANTIPSYCHOTICS | MEDICATION USE | United States - epidemiology | Antipsychotic Agents - adverse effects | Humans | Haloperidol - administration & dosage | Male | Cause of Death | Dose-Response Relationship, Drug | Dibenzothiazepines - therapeutic use | Risperidone - therapeutic use | Antipsychotic Agents - therapeutic use | Dibenzothiazepines - adverse effects | Medical Assistance - statistics & numerical data | Risperidone - adverse effects | Aged, 80 and over | Female | Nursing Homes - statistics & numerical data | Comorbidity | Dementia - drug therapy | Quetiapine Fumarate | Risperidone - administration & dosage | Haloperidol - therapeutic use | Haloperidol - adverse effects | Dibenzothiazepines - administration & dosage | Dementia - mortality | Antipsychotic Agents - administration & dosage | Epidemiologic Methods | Aged | Drug-Related Side Effects and Adverse Reactions - mortality | Psychotropic drugs | Elder care | Descriptive labeling | Health risk assessment | Index Medicus | Abridged Index Medicus
Journal Article