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Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 09/2017, Volume 138, pp. 774 - 806
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Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 06/2014, Volume 57, Issue 11, pp. 4543 - 4557
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Journal of Medicinal Chemistry, ISSN 0022-2623, 08/2014, Volume 57, Issue 15, pp. 6495 - 6512
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Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 07/2015, Volume 23, Issue 13, pp. 3436 - 3447
A series of novel spirohydantoin derivatives with arylpiperazinylbutyl moiety were synthesized and evaluated for serotonin 5-HT , 5-HT , 5-HT and dopamine D... 
D2/5-HT2A antagonist | Imidazolidine-2,4-dione spirohydantoins | Antidepressant activity | Antipsychotic activity | 5-HT1A partial agonist | partial agonist | 5-HT | antagonist | CHEMISTRY, MEDICINAL | PROTEIN | EFFICACY | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | SCHIZOPHRENIA | PSYCHOLOGICAL SYMPTOMS | IDENTIFICATION | AGONISTS | D-2/5-HT2A antagonist | 5-HT1A RECEPTOR | DOPAMINE D-3 | RECEPTOR LIGANDS | 5-HTA partial agonist | ARIPIPRAZOLE | Depression - physiopathology | Imidazolidines - pharmacology | Male | Anxiety - drug therapy | Hyperkinesis - physiopathology | Structure-Activity Relationship | Receptors, Dopamine D2 - metabolism | Receptor, Serotonin, 5-HT2A - chemistry | Antipsychotic Agents - chemical synthesis | Hyperkinesis - drug therapy | Depression - drug therapy | Anti-Anxiety Agents - chemical synthesis | Receptors, Dopamine D2 - chemistry | Antidepressive Agents - pharmacology | Hyperkinesis - chemically induced | Swimming | Receptor, Serotonin, 5-HT1A - metabolism | Hydantoins - chemical synthesis | Hydantoins - pharmacology | Imidazolidines - chemical synthesis | Anti-Anxiety Agents - pharmacology | Anxiety - physiopathology | Dextroamphetamine | Receptors, Serotonin - chemistry | Piperazines - pharmacology | Receptors, Serotonin - metabolism | Animals | Receptor, Serotonin, 5-HT1A - chemistry | Aripiprazole - pharmacology | Antidepressive Agents - chemical synthesis | Piperazines - chemical synthesis | Mice | Antipsychotic Agents - pharmacology | Receptor, Serotonin, 5-HT2A - metabolism | Antidepressants | Schizophrenia | Medical colleges | Analysis | Depression, Mental
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 02/2015, Volume 58, Issue 4, pp. 1992 - 2002
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