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Mini reviews in medicinal chemistry, ISSN 1389-5575, 2016, Volume 16, Issue 2, pp. 113 - 141
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 03/2009, Volume 324, Issue 5928, pp. 801 - 804
New drugs are required to counter the tuberculosis (TB) pandemic. Here, we describe the synthesis and characterization of 1,3-benzothiazin-4-ones (BTZs... 
Enzymes | Antibacterials | Tuberculosis | Mycobacterium tuberculosis | Cell walls | Antituberculars | Bacteria | Reports | Biochemistry | Enantiomers | Codons | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Antitubercular Agents - chemical synthesis | Antitubercular Agents - chemistry | Thiazines - therapeutic use | Ethambutol - pharmacology | Drug Resistance, Bacterial | Molecular Sequence Data | Spiro Compounds - therapeutic use | Tuberculosis - microbiology | Mycobacterium tuberculosis - drug effects | Polysaccharides - biosynthesis | Microbial Sensitivity Tests | Racemases and Epimerases - metabolism | Enzyme Inhibitors - chemistry | Spiro Compounds - chemical synthesis | Tuberculosis - drug therapy | Arabinose - metabolism | Thiazines - pharmacology | Molecular Structure | Mycobacterium tuberculosis - metabolism | Spiro Compounds - chemistry | Antitubercular Agents - therapeutic use | Amino Acid Sequence | Genes, Bacterial | Antitubercular Agents - pharmacology | Enzyme Inhibitors - pharmacology | Racemases and Epimerases - antagonists & inhibitors | Enzyme Inhibitors - therapeutic use | Thiazines - chemical synthesis | Thiazines - chemistry | Mycobacterium - genetics | Mycobacterium - drug effects | Gene Expression Regulation, Bacterial - drug effects | Animals | Cell Wall - metabolism | Enzyme Inhibitors - cerebrospinal fluid | Mice | Mice, Inbred BALB C | Spiro Compounds - pharmacology | Mycobacterium tuberculosis - genetics | Antitubercular agents | Dosage and administration | Drug therapy | Genetics | Pharmacology | Chemical synthesis | Index Medicus
Journal Article
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 02/2010, Volume 107, Issue 10, pp. 4573 - 4578
.... Consequently, there is considerable interest in understanding the mechanism by which mPTPB evades the host immune responses, and in developing potent and selective mPTPB inhibitors as unique antituberculosis (antiTB) agents... 
Cell culture techniques | Phosphatases | Mycobacterium tuberculosis | Epithelial cells | Cell lines | Libraries | Click chemistry | Macrophages | Bacterial load | Apoptosis | Combinatorial chemistry | Phosphatase inhibitor | Pathogen-host interaction | Signaling mechanism | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Antitubercular Agents - chemical synthesis | Antitubercular Agents - chemistry | Models, Chemical | Apoptosis - drug effects | Triazoles - chemistry | Humans | Benzofurans - pharmacology | Protein Tyrosine Phosphatases - metabolism | Tuberculosis - microbiology | Interferon-gamma - metabolism | Enzyme Inhibitors - chemical synthesis | Benzofurans - chemistry | Microbial Sensitivity Tests | Protein Tyrosine Phosphatases - antagonists & inhibitors | Protein Tyrosine Phosphatases - genetics | Enzyme Inhibitors - chemistry | Mycobacterium tuberculosis - physiology | Triazoles - chemical synthesis | Molecular Structure | Macrophages - microbiology | Bacterial Proteins - antagonists & inhibitors | Cell Line | Cell Survival - drug effects | Antitubercular Agents - pharmacology | Bacterial Proteins - genetics | Enzyme Inhibitors - pharmacology | Benzofurans - chemical synthesis | Host-Pathogen Interactions | Triazoles - pharmacology | Macrophages - metabolism | Animals | Mycobacterium tuberculosis - enzymology | Tuberculosis - prevention & control | Bacterial Proteins - metabolism | Macrophages - drug effects | Mice | Kinetics | Mitogen-Activated Protein Kinases - metabolism | Tyrosine | Mycobacterium | Bacterial proteins | Mycobacteria | Physiological aspects | Antitubercular agents | Research | Chemical properties | Health aspects | Index Medicus | signaling mechanism | Biological Sciences | combinatorial chemistry | phosphatase inhibitor | pathogen-host interaction
Journal Article
Journal Article
Journal Article
PloS one, ISSN 1932-6203, 10/2015, Volume 10, Issue 10, pp. e0139798 - e0139798
Journal Article
Journal Article