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Journal of Controlled Release, ISSN 0168-3659, 11/2013, Volume 172, Issue 1, pp. 137 - 143
The ultimate goal of cancer chemotherapy is to achieve a cure without causing any adverse effects. We have developed a pH-sensitive redox nanoparticle (RNP ),... 
Reactive oxygen species | Transcriptional factor | Cancer chemotherapy | Doxorubicin | Nitroxide radical | pH-responsive polymeric micelle | CELLS | OXIDATIVE STRESS | MITOCHONDRIAL-FUNCTION | DRUG-RESISTANCE | ANTITUMOR-ACTIVITY | CHEMISTRY, MULTIDISCIPLINARY | CHEMOTHERAPY | BREAST-CANCER | IN-VIVO | PHARMACOLOGY & PHARMACY | RADICAL-CONTAINING NANOPARTICLES | NF-KAPPA-B | Free Radical Scavengers - pharmacology | Neoplasms - metabolism | Doxorubicin - therapeutic use | Reactive Oxygen Species - metabolism | Antibiotics, Antineoplastic - pharmacology | Nanoparticles - chemistry | Humans | NF-kappa B - immunology | Antibiotics, Antineoplastic - adverse effects | Delayed-Action Preparations - chemistry | Inflammation - drug therapy | Free Radical Scavengers - therapeutic use | Nitrogen Oxides - therapeutic use | Oxidation-Reduction | Free Radical Scavengers - administration & dosage | Nitrogen Oxides - administration & dosage | Inflammation - immunology | Neoplasms - drug therapy | Drug Synergism | Animals | Antibiotics, Antineoplastic - therapeutic use | Neoplasms - immunology | Nitrogen Oxides - pharmacology | Mice | Mice, Inbred BALB C | Doxorubicin - adverse effects | Doxorubicin - pharmacology | Complications and side effects | Anthracyclines | Chemotherapy | Cancer | Creatine kinase | College graduates | Creatine | Adjuvants
Journal Article
Starch ‐ Stärke, ISSN 0038-9056, 03/2019, Volume 71, Issue 3-4, pp. 1800009 - n/a
It is found that Auricularia auricula‐judae (Bull.) J. Schröt Polysaccharides (AAP) and Polyphenols from Pinecones of Pinus koraiensis (PPPK) can... 
radioprotective | polysaccharide | pine polyphenol | synergistic effect | SYSTEM | CELLS | FOOD SCIENCE & TECHNOLOGY | TOXICITY | RADIATION | ANTITUMOR | DAMAGE | ANTIOXIDANT | PURIFICATION | MICE | Polyphenols | Polysaccharides
Journal Article
Nature Reviews Cancer, ISSN 1474-175X, 05/2018, Volume 18, Issue 5, pp. 313 - 322
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2013, Volume 8, Issue 1, p. e53745
Background: Ipilimumab, a cytotoxic T-lymphocyte antigen-4 (CTLA-4) blocking antibody, has been approved for the treatment of metastatic melanoma and induces... 
REGRESSION | TRIAL | INDUCED SARCOIDOSIS | CTLA-4 BLOCKADE | AUTOIMMUNITY | SAFETY | MULTIDISCIPLINARY SCIENCES | MONOCLONAL-ANTIBODY | PATIENT | HYPOPHYSITIS | CANCER | Skin Neoplasms - drug therapy | Humans | Ipilimumab | Middle Aged | Antibodies, Monoclonal - adverse effects | Antibodies, Monoclonal - therapeutic use | Male | Antineoplastic Agents - therapeutic use | Neoplasm Metastasis | Liver - drug effects | Antineoplastic Agents - adverse effects | Aged, 80 and over | Endocrine System - drug effects | Adult | Female | Retrospective Studies | Antibodies, Monoclonal - immunology | Kidney - drug effects | Antineoplastic Agents - immunology | Pancreas - drug effects | Gastrointestinal Tract - drug effects | Melanoma - pathology | CTLA-4 Antigen - immunology | Nervous System - drug effects | Melanoma - drug therapy | Respiratory System - drug effects | Aged | Skin - drug effects | Antimitotic agents | Antigens | Care and treatment | Algorithms | Lymphocytes | Melanoma | Skin | Metastasis | Antineoplastic agents | Skin cancer | Cancer | Aseptic meningitis | Guillain-Barre syndrome | Exanthema | Central nervous system | Blocking antibodies | Cytotoxicity | Oncology | Lymphocytes T | Metastases | CTLA-4 protein | Intestine | Gastroenterology | Meningitis | Internal medicine | Hematology | Sarcoidosis | Dermatology | Management | Regression analysis | Patients | Eosinophilia | Morbidity | Inflammatory bowel disease | Pathology | Side effects | Hospitals | Perforations | Medical prognosis | Antitumor activity | Autoimmune diseases | Endocrinology
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 2010, Volume 143, Issue 1, pp. 136 - 142
The use of glioblastoma-targeted drug delivery system facilitates efficient delivery of chemotherapeutic agents to malignant gliomas in the central nervous... 
c(RGDyK) | PEG-PLA micelle | Glioblastoma | Paclitaxel | C(RGDyK) | APOPTOSIS | TARGETED DRUG-DELIVERY | ANGIOGENESIS | BRAIN-TUMOR GROWTH | POLYMERIC MICELLES | ANTITUMOR-ACTIVITY | CHEMISTRY, MULTIDISCIPLINARY | PEPTIDE | IN-VIVO | PHARMACOLOGY & PHARMACY | ALPHA(V)BETA-INTEGRIN EXPRESSION | LIPOSOMES | Injections, Intravenous | Humans | Brain Neoplasms - pathology | Biological Availability | Polyethylene Glycols - chemistry | Paclitaxel - pharmacokinetics | Brain Neoplasms - metabolism | Integrin alphaVbeta3 - metabolism | Peptides, Cyclic - chemistry | Peptides, Cyclic - metabolism | Drug Carriers | Dose-Response Relationship, Drug | Paclitaxel - chemistry | Antineoplastic Agents, Phytogenic - administration & dosage | Micelles | Drug Compounding | Inhibitory Concentration 50 | Glioblastoma - metabolism | Paclitaxel - administration & dosage | Antineoplastic Agents, Phytogenic - pharmacokinetics | Lactates - chemistry | Cell Survival - drug effects | Antineoplastic Agents, Phytogenic - chemistry | Technology, Pharmaceutical - methods | Brain Neoplasms - drug therapy | Chemistry, Pharmaceutical | Particle Size | Xenograft Model Antitumor Assays | Animals | Tumor Burden - drug effects | Mice, Nude | Glioblastoma - pathology | Cell Line, Tumor | Mice | Glioblastoma - drug therapy | Drugs | Ethylene glycol | Polyethylene | Cell research | Drug delivery systems | Peptides | Gliomas | Analysis | Lactic acid | Integrins | Vehicles | Index Medicus
Journal Article
Cancer Letters, ISSN 0304-3835, 2013, Volume 356, Issue 1, pp. 105 - 113
Highlights • X-irradiation displays anti-inflammatory activities if applied at low (< 1 Gy) doses. • Pro-inflammatory effects and modulation of anti-tumour... 
Hematology, Oncology and Palliative Medicine | Bystander effects | Heat shock protein 70 | Ionizing radiation | Non-targeted effects | Abscopal effect | Immune system | NATURAL-KILLER-CELLS | SEVERE COMBINED IMMUNODEFICIENCY | BLOOD MONONUCLEAR-CELLS | HEAT-SHOCK PROTEINS | LOW-DOSE RADIOTHERAPY | IN-VITRO | ONCOLOGY | MEMBRANE-BOUND HEAT-SHOCK-PROTEIN-70 | EA.HY.926 ENDOTHELIAL-CELLS | ANTITUMOR IMMUNITY | NF-KAPPA-B | Bystander Effect - radiation effects | T-Lymphocytes, Cytotoxic - immunology | Genomic Instability - radiation effects | Lymphocyte Activation - radiation effects | HSP70 Heat-Shock Proteins - immunology | Anti-Inflammatory Agents | Apoptosis - radiation effects | Dendritic Cells - immunology | Humans | HSP90 Heat-Shock Proteins - radiation effects | Inflammation - immunology | MicroRNAs - immunology | Lymphocyte Activation - immunology | Animals | Apoptosis - immunology | HSP90 Heat-Shock Proteins - immunology | Cell Nucleus - radiation effects | Neoplasms - immunology | Inflammation - radiotherapy | Mice | Signal Transduction - radiation effects | Bystander Effect - immunology | Cytokines - biosynthesis | HSP70 Heat-Shock Proteins - radiation effects | Heat shock proteins | Chemotherapy | Analysis | Immunotherapy | Cancer | Pain | Peptides | Analgesics | Rodents | Mortality | Radiation therapy | Chemokines | Deoxyribonucleic acid--DNA
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2015, Volume 16, Issue 13, pp. e498 - e509
Journal Article