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Science Translational Medicine, ISSN 1946-6234, 12/2015, Volume 7, Issue 318, p. 318ra200
Autoantibodies to components of apoptotic cells, such as anti-perlecan antibodies, contribute to rejection in organ transplant recipients. However, mechanisms... 
SOLID-ORGAN TRANSPLANTATION | MEDICINE, RESEARCH & EXPERIMENTAL | ACUTE KIDNEY INJURY | SYSTEMIC-LUPUS-ERYTHEMATOSUS | CORONARY-ARTERY DISEASE | EXTRACELLULAR VESICLES | ANTIVIMENTIN ANTIBODIES | PERLECAN FRAGMENT LG3 | NON-HLA ANTIBODIES | MESENCHYMAL STEM-CELLS | CHRONIC ALLOGRAFT NEPHROPATHY | CELL BIOLOGY | Cell-Derived Microparticles - enzymology | Humans | Muscle, Smooth, Vascular - immunology | Immunity, Humoral | Ischemia - immunology | Time Factors | Peptide Fragments - immunology | Exosomes - immunology | Acute Kidney Injury - immunology | Proteomics - methods | Graft Rejection - pathology | Proteasome Endopeptidase Complex - immunology | Ischemia - pathology | Aorta - transplantation | Disease Models, Animal | Biomarkers - metabolism | Acute Kidney Injury - pathology | Myocytes, Smooth Muscle - enzymology | Rats | Aorta - immunology | Acute Kidney Injury - enzymology | Aorta - pathology | Human Umbilical Vein Endothelial Cells - enzymology | Exosomes - enzymology | Human Umbilical Vein Endothelial Cells - pathology | Mice, Inbred BALB C | Graft Rejection - immunology | Proteasome Endopeptidase Complex - metabolism | Muscle, Smooth, Vascular - enzymology | Ischemia - enzymology | Myocytes, Smooth Muscle - pathology | Human Umbilical Vein Endothelial Cells - immunology | Exosomes - pathology | Autoantibodies - biosynthesis | Allografts | Cell-Derived Microparticles - pathology | Kidney Tubules, Proximal - enzymology | Aorta - enzymology | Graft Rejection - enzymology | Kidney Tubules, Proximal - immunology | Kidney Tubules, Proximal - pathology | Peptide Fragments - metabolism | Mice, Inbred C57BL | Cells, Cultured | Heparan Sulfate Proteoglycans - immunology | Autoantibodies - immunology | Muscle, Smooth, Vascular - pathology | Animals | Apoptosis - immunology | Cell-Derived Microparticles - immunology | Heparan Sulfate Proteoglycans - metabolism | Myocytes, Smooth Muscle - immunology
Journal Article
Journal Article
Journal Article
Infection and Immunity, ISSN 0019-9567, 2015, Volume 83, Issue 12, pp. 4582 - 4593
The American Heart Association supports an association between periodontal diseases and atherosclerosis but not a causal association. This study explores the... 
Integrins - deficiency | Periodontitis - microbiology | Adventitia - microbiology | Integrins - genetics | Porphyromonas gingivalis - growth & development | Gingiva - pathology | Periodontium - pathology | Atherosclerosis - microbiology | Disease Models, Animal | Plaque, Atherosclerotic - complications | Atherosclerosis - pathology | Bone Resorption | Gene Expression | Atherosclerosis - immunology | Antigens, Neoplasm - immunology | Aorta - immunology | In Situ Hybridization, Fluorescence | Plaque, Atherosclerotic - immunology | Mice, Knockout | Aorta - pathology | Aorta - microbiology | Fusobacterium nucleatum - pathogenicity | Adventitia - pathology | Mice | Lipoproteins, LDL - immunology | Gingiva - immunology | Porphyromonas gingivalis - pathogenicity | Treponema denticola - pathogenicity | Treponema denticola - immunology | Adventitia - immunology | Periodontium - microbiology | Fusobacterium nucleatum - immunology | Lipoproteins, LDL - genetics | Microbial Consortia | Treponema denticola - growth & development | Plaque, Atherosclerotic - microbiology | Bacteroidetes - immunology | Periodontium - immunology | Plaque, Atherosclerotic - pathology | Porphyromonas gingivalis - immunology | Antigens, Neoplasm - genetics | Periodontitis - immunology | Inflammasomes | Integrins - immunology | Periodontitis - pathology | Atherosclerosis - complications | Bacteroidetes - pathogenicity | Animals | Bacteroidetes - growth & development | Periodontitis - complications | Gingiva - microbiology | Fusobacterium nucleatum - growth & development | Host Response and Inflammation
Journal Article
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 08/2013, Volume 33, Issue 8, pp. 1986 - 1993
Journal Article
Circulation, ISSN 0009-7322, 03/2011, Volume 123, Issue 10, pp. 1083 - 1091
Journal Article
American Journal of Physiology - Endocrinology and Metabolism, ISSN 0193-1849, 05/2016, Volume 310, Issue 9, pp. E762 - E773
ApoE-null (ApoE-KO) mice fed a high-fat diet (HFD) develop atherosclerosis, due in part to activation of vascular inflammation by oxidized low-density... 
Osteoporosis | Osteoclasts | Wnt signaling | Inflammation | Bone remodeling | Osteoblasts | Atherosclerosis - genetics | Cell Count | Tumor Necrosis Factor-alpha - genetics | Wnt Signaling Pathway - immunology | Bone Diseases, Metabolic - pathology | Monocytes - immunology | Femur - diagnostic imaging | Interleukin-1beta - genetics | Osteoclasts - cytology | Wnt Proteins - metabolism | X-Ray Microtomography | Cancellous Bone - immunology | Cancellous Bone - diagnostic imaging | Immunomagnetic Separation | Bone and Bones - metabolism | Diet, High-Fat | Tumor Necrosis Factor-alpha - immunology | Spine - immunology | Lipoproteins, LDL - metabolism | Atherosclerosis - pathology | Atherosclerosis - immunology | Interleukin-6 - genetics | Femur - metabolism | Femur - immunology | Reverse Transcriptase Polymerase Chain Reaction | Absorptiometry, Photon | Blotting, Western | Mice, Knockout | Aorta - pathology | Wnt Proteins - immunology | Cortical Bone - drug effects | Interleukin-6 - immunology | Mice | Bone Diseases, Metabolic - genetics | Bone and Bones - pathology | Femur - pathology | Cancellous Bone - metabolism | Spine - metabolism | Cortical Bone - pathology | Flow Cytometry | Wnt Proteins - genetics | Cortical Bone - immunology | Bone and Bones - diagnostic imaging | Cancellous Bone - pathology | Female | Osteoblasts - cytology | Spine - pathology | Macrophages - immunology | Arachidonate 12-Lipoxygenase - genetics | Bone Density | Bone Diseases, Metabolic - diagnostic imaging | Bone Diseases, Metabolic - immunology | Interleukin-1beta - immunology | Cortical Bone - metabolism | Spine - diagnostic imaging | Animals | Arachidonate 15-Lipoxygenase - genetics | Wnt Signaling Pathway - genetics | Apolipoproteins E - genetics | Bone and Bones - immunology | Porosity | Osteogenesis | Medical research | Atherosclerosis | Physiological aspects | Medicine, Experimental | Skeleton | Research | Wnt proteins | Health aspects | inflammation | osteoclasts | bone remodeling | osteoblasts | osteoporosis
Journal Article
Human Immunology, ISSN 0198-8859, 2011, Volume 72, Issue 12, pp. 1150 - 1159
Abstract Chronic rejection manifests as transplant vasculopathy, which is characterized by intimal thickening of the vessels of the allograft. Intimal... 
Allergy and Immunology | Anti-HLA antibodies | Cell proliferation | Focal adhesion kinase | Cell migration | Human smooth muscle cells | RNA INTERFERENCE | ACTIVATION | TRANSPLANT ARTERIOPATHY | IMMUNOLOGY | MHC CLASS-I | HEART | LUNG TRANSPLANTATION | PATHWAY | ENDOTHELIAL-CELLS | MICE | REGULATES PROLIFERATION | RNA, Small Interfering - genetics | Graft Survival - immunology | Phosphorylation | Humans | Graft Rejection - metabolism | Muscle, Smooth, Vascular - immunology | Organ Transplantation | Proto-Oncogene Proteins c-akt - genetics | Cell Movement - immunology | Histocompatibility Antigens Class I - metabolism | Signal Transduction - immunology | Flow Cytometry | Transfection | Mitogen-Activated Protein Kinase 1 - genetics | Antibodies - immunology | Myocytes, Smooth Muscle - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Focal Adhesion Kinase 1 - metabolism | Myocytes, Smooth Muscle - cytology | Muscle, Smooth, Vascular - drug effects | Focal Adhesion Kinase 1 - immunology | Mitogen-Activated Protein Kinase 3 - immunology | Mitogen-Activated Protein Kinase 1 - immunology | Mitogen-Activated Protein Kinase 3 - genetics | Gene Expression Regulation - immunology | Aorta - drug effects | Cells, Cultured | Histocompatibility Antigens Class I - immunology | Aorta - immunology | Antibodies - adverse effects | Muscle, Smooth, Vascular - cytology | Antibodies - pharmacology | Cell Movement - drug effects | Proto-Oncogene Proteins c-akt - immunology | Mitogen-Activated Protein Kinase 3 - metabolism | Myocytes, Smooth Muscle - immunology | Cell Proliferation - drug effects | Aorta - cytology | Graft Rejection - immunology | Graft Rejection - genetics | Focal Adhesion Kinase 1 - antagonists & inhibitors | Mitogen-Activated Protein Kinase 1 - metabolism | RNA, Small Interfering - metabolism | Viral antibodies | Proteins | Antibodies | Immunogenetics | Histocompatibility antigens | HLA histocompatibility antigens
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 06/2016, Volume 36, Issue 6, pp. 1174 - 1185
OBJECTIVE—Explore aorta B-cell immunity in aged apolipoprotein E-deficient (ApoE) mice. APPROACH AND RESULTS—Transcript maps, fluorescence-activated cell... 
atherosclerosis | B-lymphocytes | aging | germinal center | inflammation | REGULATORY FUNCTION | DEPLETION | LASER-CAPTURE MICRODISSECTION | ADAPTIVE IMMUNITY | LIVED PLASMA-CELLS | NULL MICE | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | AUTOIMMUNE-DISEASE | NZB/W MICE | HYPERCHOLESTEROLEMIC MICE | MAJOR SITE | Autoimmunity | Tertiary Lymphoid Structures - immunology | Apolipoproteins E - deficiency | Atherosclerosis - genetics | Autoantibodies - blood | Germinal Center - immunology | Transcriptome | Male | Aorta - metabolism | Aortic Diseases - metabolism | Aging - immunology | Aging - genetics | Immunoglobulins - blood | Plasma Cells - metabolism | B-Lymphocytes - metabolism | Aortic Diseases - pathology | Disease Models, Animal | Atherosclerosis - pathology | Genetic Predisposition to Disease | Atherosclerosis - immunology | Cytokines - metabolism | Signal Transduction | Aortic Diseases - immunology | Malondialdehyde - analogs & derivatives | Mice, Inbred C57BL | Gene Expression Regulation | Lymph Nodes - metabolism | Aorta - immunology | Lymph Nodes - immunology | Atherosclerosis - metabolism | Mice, Knockout | Tertiary Lymphoid Structures - pathology | Aorta - pathology | Aortic Diseases - genetics | Phenotype | Animals | B-Lymphocytes - immunology | Germinal Center - metabolism | Malondialdehyde - immunology | Apolipoproteins E - genetics | Tertiary Lymphoid Structures - metabolism | Immunologic Memory | Lipoproteins, LDL - immunology | Aging - metabolism | Plasma Cells - immunology | 10195 | 10187 | 10188 | Basic Sciences
Journal Article
Immunity, ISSN 1074-7613, 06/2015, Volume 42, Issue 6, pp. 1100 - 1115
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 11/2005, Volume 25, Issue 11, pp. 2386 - 2391
Journal Article