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Journal Article
Annals of Vascular Surgery, ISSN 0890-5096, 2017, Volume 43, pp. 56 - 64
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 07/2017, Volume 37, Issue 11, pp. 2102 - 2102
OBJECTIVE—The role of TGF-β (transforming growth factor-β) signaling in abdominal aortic aneurysm (AAA) formation is controversial. Others reported that... 
aneurysm | smooth muscle | SERVICES TASK-FORCE | ATHEROSCLEROSIS | RECEPTOR | mice | macrophages | TGF-beta | DISRUPTION | angiotensin II | ANEURYSM MOUSE MODEL | PERIPHERAL VASCULAR DISEASE | aorta | SMOOTH-MUSCLE-CELLS | APOE(-/-) MICE | HEMATOLOGY | E-DEFICIENT MICE | PROMOTES | PROGRESSION | Protein-Serine-Threonine Kinases - deficiency | Tunica Media - pathology | Aortic Aneurysm, Abdominal - chemically induced | Receptors, Transforming Growth Factor beta - genetics | Aortic Aneurysm, Abdominal - prevention & control | Muscle, Smooth, Vascular - metabolism | Transforming Growth Factor beta1 - antagonists & inhibitors | Transforming Growth Factor beta2 - metabolism | Aortic Aneurysm, Thoracic - prevention & control | Transforming Growth Factor beta1 - metabolism | Male | Aortic Aneurysm, Thoracic - chemically induced | Transforming Growth Factor beta3 - metabolism | Aorta, Abdominal - drug effects | Aortic Aneurysm, Abdominal - metabolism | Adventitia - metabolism | Receptor, Transforming Growth Factor-beta Type II | Aortic Aneurysm, Thoracic - pathology | Tunica Media - metabolism | Transforming Growth Factor beta - antagonists & inhibitors | Female | Aorta, Abdominal - pathology | Aorta, Thoracic - drug effects | Vascular Remodeling - drug effects | Angiotensin II | Aorta, Abdominal - metabolism | Dilatation, Pathologic | Aorta, Thoracic - pathology | Aortic Aneurysm, Abdominal - pathology | Disease Models, Animal | Muscle, Smooth, Vascular - drug effects | Severity of Illness Index | Genetic Predisposition to Disease | Mice, Inbred C57BL | Protein-Serine-Threonine Kinases - genetics | Aorta, Thoracic - metabolism | Transforming Growth Factor beta3 - antagonists & inhibitors | Mice, Knockout | Antibodies - pharmacology | Muscle, Smooth, Vascular - pathology | Phenotype | Animals | Signal Transduction - drug effects | Aortic Aneurysm, Thoracic - metabolism | Transforming Growth Factor beta2 - antagonists & inhibitors | Adventitia - pathology | Transforming Growth Factor beta - metabolism | Receptors, Transforming Growth Factor beta - deficiency | Index Medicus | growth factor | Animal Models of Human Disease | Vascular Disease | Genetically Altered and Transgenic Models | Aortic Dissection | genetically altered mice
Journal Article
Journal Article
Journal Article
Journal Article
Arthritis Care and Research, ISSN 2151-4658, 03/2010, Volume 62, Issue 3, pp. 316 - 322
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 04/2015, Volume 35, Issue 4, pp. 911 - 917
Objective-Studies of mice with mild Marfan syndrome (MFS) have correlated the development of thoracic aortic aneurysm (TAA) with improper stimulation of... 
aortic aneurysm | receptor, angiotensin, type 1 | losartan | transforming growth factor β | Marfan syndrome | PATHOGENESIS | TGF-BETA | type 1 | transforming growth factor beta | MOUSE MODEL | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | receptor, angiotensin | Aortic Aneurysm, Thoracic - genetics | Phosphorylation | Aortic Aneurysm, Thoracic - prevention & control | Humans | Aortic Rupture - metabolism | Mice, 129 Strain | Angiotensin II Type 1 Receptor Blockers - pharmacology | Marfan Syndrome - drug therapy | Aortic Aneurysm, Thoracic - pathology | Time Factors | Mice, Mutant Strains | Aortic Rupture - prevention & control | Transforming Growth Factor beta - antagonists & inhibitors | Aorta, Thoracic - drug effects | Microfilament Proteins - genetics | Aorta, Thoracic - pathology | Disease Models, Animal | Transforming Growth Factor beta - immunology | Fibrillin-1 | Mice, Inbred C57BL | Losartan - pharmacology | Smad2 Protein - metabolism | Aorta, Thoracic - metabolism | Antibodies, Neutralizing - pharmacology | Aortic Rupture - pathology | Fibrillins | Disease Progression | Marfan Syndrome - genetics | Animals | Mitogen-Activated Protein Kinase 3 - metabolism | Signal Transduction - drug effects | Aortic Aneurysm, Thoracic - metabolism | Receptor, Angiotensin, Type 1 - metabolism | Aortic Rupture - genetics | Marfan Syndrome - metabolism | Marfan Syndrome - pathology | Mutation | Transforming Growth Factor beta - metabolism | Mitogen-Activated Protein Kinase 1 - metabolism | Index Medicus
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 03/2016, Volume 126, Issue 3, pp. 948 - 961
Journal Article
Arteriosclerosis, thrombosis, and vascular biology, ISSN 1079-5642, 04/2015, Volume 35, Issue 4, pp. 888 - 898
Objective-Aortic aneurysm, focal dilation of the aorta, results from impaired integrity of aortic extracellular matrix (ECM). Matrix metalloproteinases (MMPs)... 
aortic aneurysm, thoracic | matrix metalloproteinase 2 | ACTIVATION | TGF-BETA | CONVERTING ENZYME-INHIBITORS | ANGIOTENSIN RECEPTOR BLOCKERS | aortic aneurysm | GROWTH-FACTOR-BETA | GENE | MARFAN-SYNDROME | TISSUE INHIBITOR | DOXYCYCLINE | PERIPHERAL VASCULAR DISEASE | EXTRACELLULAR-MATRIX | HEMATOLOGY | thoracic | Aortic Aneurysm, Thoracic - genetics | Vascular Remodeling | Aortic Aneurysm, Thoracic - prevention & control | Myocytes, Smooth Muscle - pathology | Male | Smad3 Protein - metabolism | Aortic Aneurysm, Thoracic - chemically induced | RNA, Messenger - metabolism | Muscle, Smooth, Vascular - diagnostic imaging | Aortic Aneurysm, Thoracic - diagnosis | Ultrasonography | Collagen - genetics | Angiotensin II | Dilatation, Pathologic | Aorta, Thoracic - pathology | Disease Models, Animal | Elastin - metabolism | Calcium Chloride | Signal Transduction | Aortic Aneurysm, Thoracic - enzymology | Matrix Metalloproteinase 2 - metabolism | Myocytes, Smooth Muscle - enzymology | Mice, Inbred C57BL | Cells, Cultured | Smad2 Protein - metabolism | Genotype | Aorta, Thoracic - enzymology | Collagen - metabolism | Matrix Metalloproteinase 2 - genetics | Muscle, Smooth, Vascular - pathology | Phenotype | Animals | Elastin - genetics | Matrix Metalloproteinase 2 - deficiency | Muscle, Smooth, Vascular - enzymology | Transforming Growth Factor beta - metabolism | Aorta, Thoracic - diagnostic imaging | Index Medicus
Journal Article