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Journal Article
Journal Article
British Journal of Dermatology, ISSN 0007-0963, 12/2015, Volume 173, Issue 6, pp. 1505 - 1513
Journal Article
Journal Article
Journal Article
Arteriosclerosis, thrombosis, and vascular biology, ISSN 1524-4636, 2017, Volume 37, Issue 2, pp. 328 - 340
OBJECTIVE—The calcium composition of atherosclerotic plaque is thought to be associated with increased risk for cardiovascular events, but whether plaque... 
atherosclerosis | coronary artery disease | macrophages | inflammation | biomarkers | C-REACTIVE PROTEIN | CORONARY-ARTERY CALCIUM | CARDIOVASCULAR EVENTS | VASCULAR CALCIFICATION | VULNERABLE PATIENT | RECEPTOR | RISK-ASSESSMENT STRATEGIES | PLAQUE | SMOOTH-MUSCLE | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | Up-Regulation | Prognosis | Apolipoproteins E - deficiency | Atherosclerosis - genetics | Humans | Myocytes, Smooth Muscle - pathology | rac GTP-Binding Proteins - deficiency | rac GTP-Binding Proteins - metabolism | Male | Coronary Artery Disease - enzymology | Atherosclerosis - enzymology | Transfection | Interleukin-1beta - metabolism | rac GTP-Binding Proteins - genetics | Coronary Artery Disease - pathology | Inflammation Mediators - metabolism | Aortic Diseases - prevention & control | Vascular Calcification - mortality | Female | Vascular Calcification - enzymology | Aortic Diseases - enzymology | Interleukin 1 Receptor Antagonist Protein - pharmacology | Aorta - enzymology | Aortic Diseases - pathology | Atherosclerosis - pathology | Coronary Vessels - pathology | Genetic Predisposition to Disease | Coronary Vessels - enzymology | Macrophages - pathology | Signal Transduction | Myocytes, Smooth Muscle - enzymology | Mice, Inbred C57BL | Cells, Cultured | Neuropeptides - metabolism | Coronary Artery Disease - mortality | Plaque, Atherosclerotic | Vascular Calcification - pathology | Macrophages - enzymology | Mice, Knockout | Aorta - pathology | Aortic Diseases - genetics | Muscle, Smooth, Vascular - pathology | Phenotype | Animals | Apolipoproteins E - genetics | Muscle, Smooth, Vascular - enzymology | Atherosclerosis - prevention & control | rac1 GTP-Binding Protein - metabolism
Journal Article
Circulation (New York, N.Y.), ISSN 1524-4539, 2007, Volume 115, Issue 3, pp. 377 - 386
...) molecular imaging can detect early changes in aortic valve disease, we used in vivo a panel of near-infrared fluorescence imaging agents to map endothelial cells, macrophages, proteolysis... 
Stenosis | Valves | Inflammation | Hypercholesterolemia | Imaging | Atherosclerosis | atherosclerosis | ACTIVATION | CARDIAC & CARDIOVASCULAR SYSTEMS | valves | CELL PHENOTYPE | ADHESION MOLECULES | stenosis | imaging | POTENTIAL MECHANISM | hypercholesterolemia | MATRIX METALLOPROTEINASES | inflammation | HEART-VALVES | CALCIFICATION | PERIPHERAL VASCULAR DISEASE | EXPRESSION | Predictive Value of Tests | Osteogenesis - physiology | Calcium - metabolism | Fibroblasts - physiology | Magnetic Resonance Imaging - methods | Gene Expression Profiling | Spectroscopy, Near-Infrared - methods | Hypercholesterolemia - pathology | Peptide Hydrolases - physiology | Macrophage Activation - physiology | Macrophages - physiology | Atherosclerosis - pathology | Macrophages - pathology | Atherosclerosis - physiopathology | Mice, Inbred C57BL | Osteoblasts - physiology | Aortic Valve Stenosis - physiopathology | Endothelium, Vascular - physiopathology | Fibroblasts - pathology | Mice, Knockout | Osteoblasts - pathology | Animals | Aortic Valve Stenosis - pathology | Apolipoproteins E - genetics | Apolipoproteins E - physiology | Endothelium, Vascular - pathology | Hypercholesterolemia - physiopathology | Mice | Calcinosis - pathology | Enzyme Activation - physiology | Calcinosis - physiopathology | Proteolysis | Growth | Aortic valve stenosis | Analysis | Bones | Diagnosis | Research | Cardiography | Methods
Journal Article
American journal of human genetics, ISSN 0002-9297, 2009, Volume 84, Issue 5, pp. 617 - 627
Journal Article
Cardiovascular research, ISSN 1755-3245, 2015, Volume 108, Issue 3, pp. 377 - 386
Neointimal hyperplasia is a common feature of fibro-proliferative vascular disease and characterizes initial stages of atherosclerosis... 
ARTERIAL INJURY | MYOCARDIN | PULMONARY-HYPERTENSION | Neointimal hyperplasia | ATHEROSCLEROSIS | CADHERIN EXPRESSION | SMOOTH-MUSCLE-CELL | FLOW | Fibrosis | ERK5 | IN-VIVO | GROWTH | Shear stress | GENE-EXPRESSION | Endothelial-to-mesenchymal transition | ACTIVATION | CARDIAC & CARDIOVASCULAR SYSTEMS | MECHANISMS | SMOOTH-MUSCLE-CELLS | EXPRESSION | TRANSDIFFERENTIATION | Carotid Arteries - metabolism | Vascular Remodeling | Cell Proliferation | Human Umbilical Vein Endothelial Cells - metabolism | Humans | Carotid Artery Diseases - physiopathology | Stress, Mechanical | Male | Aortic Diseases - metabolism | Neointima | Transfection | RNA Interference | Time Factors | Carotid Artery Diseases - pathology | Swine | MAP Kinase Kinase 5 - metabolism | Epithelial-Mesenchymal Transition | HEK293 Cells | Carotid Artery Diseases - metabolism | Aorta, Thoracic - pathology | Aortic Diseases - pathology | Disease Models, Animal | Endothelial Cells - metabolism | Mice, Inbred C57BL | Aorta, Thoracic - metabolism | Mitogen-Activated Protein Kinase 7 - genetics | MAP Kinase Kinase 5 - genetics | Mitogen-Activated Protein Kinase 7 - metabolism | Aorta, Thoracic - physiopathology | Plaque, Atherosclerotic | Regional Blood Flow | Mechanotransduction, Cellular | Aortic Diseases - genetics | Aortic Diseases - physiopathology | Animals | Carotid Arteries - physiopathology | Carotid Artery Diseases - genetics | Human Umbilical Vein Endothelial Cells - pathology | Carotid Arteries - pathology | Endothelial Cells - pathology
Journal Article
Circulation (New York, N.Y.), ISSN 1524-4539, 2009, Volume 119, Issue 13, pp. 1785 - 1794
Background-Clinical studies have demonstrated that 50% of individuals with chronic renal disease (CRD... 
Calcification | Chronic | Kidney failure | Aortic valve | Elastin | Atherosclerosis | atherosclerosis | kidney failure, chronic | aortic valve | ELASTIN PEPTIDES | CARDIAC & CARDIOVASCULAR SYSTEMS | ATHEROSCLEROTIC PLAQUES | VASCULAR CALCIFICATION | elastin | POTENTIAL MECHANISM | FAILURE | IN-VIVO | CYSTATIN-C | PERIPHERAL VASCULAR DISEASE | SMOOTH-MUSCLE-CELLS | calcification | CHRONIC KIDNEY-DISEASE | VULNERABLE PLAQUE | Tunica Media - pathology | Osteogenesis - physiology | Cystatin C - blood | Humans | Carotid Artery Diseases - physiopathology | Aorta - metabolism | Aortic Valve - pathology | Nephrectomy | Carotid Artery Diseases - pathology | Mice, Mutant Strains | Tunica Media - metabolism | Phosphates - blood | Calcinosis - metabolism | Carotid Artery Diseases - metabolism | Phosphates - pharmacology | Muscle, Smooth, Vascular - physiology | Kidney Failure, Chronic - physiopathology | Elastin - metabolism | Mice, Inbred C57BL | Osteogenesis - drug effects | Aortic Valve Stenosis - physiopathology | Cells, Cultured | Elastin - pharmacology | Muscle, Smooth, Vascular - cytology | Aortic Valve - metabolism | Kidney Failure, Chronic - metabolism | Aorta - pathology | Tunica Intima - metabolism | Animals | Aortic Valve Stenosis - pathology | Tunica Intima - pathology | Cathepsins - genetics | Cathepsins - metabolism | Apolipoproteins E - genetics | Creatinine - blood | Aortic Valve Stenosis - metabolism | Mice | Calcinosis - pathology | Cathepsins - deficiency | Calcinosis - physiopathology | Cathepsins | Physiological aspects | Research | Chronic kidney failure | Diseases
Journal Article
Circulation (New York, N.Y.), ISSN 0009-7322, 06/2015, Volume 131, Issue 24, pp. 2104 - 2113
Background-Data are limited on the presence, distribution, and extent of subclinical atherosclerosis in middle-aged populations. Methods and Results-The PESA... 
Population | Epidemiology | Risk assessment | Atherosclerosis | Ultrasonography | Multidetector computed tomography | atherosclerosis | YOUNG-ADULTS | risk assessment | CARDIAC & CARDIOVASCULAR SYSTEMS | CORONARY-ARTERY CALCIUM | EVENTS | ultrasonography | ANKLE-BRACHIAL INDEX | RISK | PLAQUE | population | epidemiology | HEART-DISEASE | multidetector computed tomography | CARDIOVASCULAR-DISEASE | CALCIFICATION | PERIPHERAL VASCULAR DISEASE | HEALTH | Aortic Diseases - diagnostic imaging | Femoral Artery - pathology | Iliac Artery - pathology | Plaque, Atherosclerotic - diagnostic imaging | Prevalence | Prospective Studies | Age Factors | Follow-Up Studies | Ankle Brachial Index | Humans | Middle Aged | Calcinosis - diagnostic imaging | Male | Plaque, Atherosclerotic - epidemiology | Asymptomatic Diseases | Atherosclerosis - epidemiology | Aorta, Abdominal - diagnostic imaging | Atherosclerosis - diagnostic imaging | Carotid Artery Diseases - diagnostic imaging | Carotid Artery Diseases - pathology | Coronary Artery Disease - pathology | Adult | Female | Aorta, Abdominal - pathology | Aortic Diseases - pathology | Multidetector Computed Tomography | Atherosclerosis - pathology | Aortic Diseases - epidemiology | Comorbidity | Risk Factors | Carotid Artery Diseases - epidemiology | Disease Progression | Calcinosis - epidemiology | Coronary Angiography | Coronary Artery Disease - diagnostic imaging | Femoral Artery - diagnostic imaging | Iliac Artery - diagnostic imaging | Spain - epidemiology | Coronary Artery Disease - epidemiology | Aortography | Calcinosis - pathology
Journal Article