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1. Full Text Bicuspid Aortic Cusp Fusion Morphology Alters Aortic Three-Dimensional Outflow Patterns, Wall Shear Stress, and Expression of Aortopathy
by Mahadevia, Riti and Barker, Alex J and Schnell, Susanne and Entezari, Pegah and Kansal, Preeti and Fedak, Paul W.M and Malaisrie, S Chris and McCarthy, Patrick and Collins, Jeremy and Carr, James and Markl, Michael
Circulation, ISSN 0009-7322, 02/2014, Volume 129, Issue 6, pp. 673 - 682
BACKGROUND—Aortic 3-dimensional blood flow was analyzed to investigate altered ascending aorta (AAo) hemodynamics in bicuspid aortic valve (BAV) patients and... 
Hemodynamics | Magnetic resonance imaging | Aortic diseases | Bicuspid aortic valve | ASCENDING AORTA | magnetic resonance imaging | CARDIAC & CARDIOVASCULAR SYSTEMS | SYSTOLIC FLOW | MANAGEMENT | FLOW PATTERNS | QUANTIFICATION | aortic diseases | CLASSIFICATION | BLOOD-FLOW | hemodynamics | bicuspid aortic valve | MAGNETIC-RESONANCE | PERIPHERAL VASCULAR DISEASE | PHASE-CONTRAST MRI | VALVE DISEASE | Prevalence | Heart Valve Diseases - pathology | Humans | Middle Aged | Magnetic Resonance Imaging - methods | Stress, Mechanical | Male | Aortic Valve - pathology | Young Adult | Heart Valve Diseases - epidemiology | Adult | Female | Aorta - physiopathology | Imaging, Three-Dimensional | Aortic Diseases - pathology | Heart Valve Diseases - physiopathology | Aortic Diseases - epidemiology | Heart Defects, Congenital - pathology | Aortic Valve - physiopathology | Aorta - pathology | Aortic Diseases - physiopathology | Blood Flow Velocity | Heart Defects, Congenital - epidemiology | Aged | Heart Defects, Congenital - physiopathology | Evaluation | Mitral valve | Shear (Mechanics) | Research | Blood flow
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2. Full Text Calcific Aortic Valve Disease: A Consensus Summary From the Alliance of Investigators on Calcific Aortic Valve Disease
by Yutzey, Katherine E and Demer, Linda L and Body, Simon C and Huggins, Gordon S and Towler, Dwight A and Giachelli, Cecilia M and Hofmann-Bowman, Marion A and Mortlock, Douglas P and Rogers, Melissa B and Sadeghi, Mehran M and Aikawa, Elena
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 11/2014, Volume 34, Issue 11, pp. 2387 - 2393
Calcific aortic valve disease (CAVD) is increasingly prevalent worldwide with significant morbidity and mortality. Therapeutic options beyond surgical valve... 
Calcification | Aortic valve stenosis | Inflammation | VALVULAR CALCIFICATION | METABOLIC SYNDROME | STENOSIS | VASCULAR CALCIFICATION | aortic valve stenosis | LOW-DENSITY-LIPOPROTEIN | OSTEOPROTEGERIN | HEART | POSITRON-EMISSION-TOMOGRAPHY | inflammation | PERIPHERAL VASCULAR DISEASE | calcification | HEMATOLOGY | ASSOCIATION | PROGRESSION | Heart Valve Diseases - physiopathology | Calcinosis - diagnosis | Heart Valve Prosthesis Implantation | Humans | Aortic Valve Stenosis - physiopathology | Aortic Valve - physiopathology | Biomedical Research - trends | Aortic Valve Stenosis - diagnosis | Aortic Valve Stenosis - therapy | Hemodynamics - physiology | Aortic Valve - pathology | Calcinosis - therapy | Cardiac Surgical Procedures | Heart Defects, Congenital - diagnosis | Heart Valve Diseases - therapy | Signal Transduction - physiology | Heart Defects, Congenital - physiopathology | Heart Defects, Congenital - therapy | Heart Valve Diseases - diagnosis | Calcinosis - physiopathology | aortic stenosis | Calcific aortic valve disease
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3. Full Text Central Pressure More Strongly Relates to Vascular Disease and Outcome Than Does Brachial Pressure: The Strong Heart Study
by Roman, Mary J and Devereux, Richard B and Kizer, Jorge R and Lee, Elisa T and Galloway, James M and Ali, Tauqeer and Umans, Jason G and Howard, Barbara V
Hypertension, ISSN 0194-911X, 07/2007, Volume 50, Issue 1, pp. 197 - 203
Brachial blood pressure is predictive of cardiovascular outcome; however central pressure may better represent the load imposed on the coronary and cerebral... 
Arterial stiffness | Blood pressure | Atherosclerosis | arterial stiffness | atherosclerosis | blood pressure | INDEPENDENT PREDICTOR | PULSE-WAVE VELOCITY | MYOCARDIAL-INFARCTION | ASCENDING AORTIC PRESSURE | AMERICAN-INDIANS | CARDIOVASCULAR-DISEASE | PERIPHERAL VASCULAR DISEASE | DIASTOLIC BLOOD-PRESSURE | HYPERTENSIVE SUBJECTS | STAGE RENAL-DISEASE | Blood Pressure | Cerebrovascular Disorders - physiopathology | Outcome Assessment (Health Care) | Humans | Middle Aged | Carotid Artery Diseases - physiopathology | Male | Blood Pressure Determination - methods | Carotid Artery Diseases - diagnostic imaging | Cerebrovascular Disorders - diagnostic imaging | Ultrasonography | Brachial Artery - physiopathology | Female | Aged | Aorta - physiopathology | Intracranial Arteriosclerosis - diagnostic imaging | Intracranial Arteriosclerosis - physiopathology | Cohort Studies | Hypertrophy
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4. Full Text Arterial stiffness and pulse pressure in CKD and ESRD
by Briet, Marie and Boutouyrie, Pierre and Laurent, Stéphane and London, Gérard M
Kidney International, ISSN 0085-2538, 08/2012, Volume 82, Issue 4, pp. 388 - 400
We recognize that increased systolic pressure is the most challenging form of hypertension today and that pulse pressure as an independent cardiovascular risk... 
arterial stiffness | chronic kidney disease | arterial remodeling | end-stage renal disease | arterial aging | VASCULAR CALCIFICATION | FETUIN-A CONCENTRATION | AORTIC STIFFNESS | LEFT-VENTRICULAR HYPERTROPHY | WAVE VELOCITY | GLOMERULAR-FILTRATION-RATE | SHEAR-STRESS | CARDIOVASCULAR-DISEASE | UROLOGY & NEPHROLOGY | CHRONIC KIDNEY-DISEASE | STAGE RENAL-DISEASE | Kidney Failure, Chronic - physiopathology | Cardiovascular Diseases - etiology | Cardiovascular Diseases - physiopathology | Prognosis | Age Factors | Risk Assessment | Atherosclerosis - physiopathology | Cardiovascular Diseases - prevention & control | Humans | Risk Factors | Renal Insufficiency, Chronic - complications | Renal Insufficiency, Chronic - physiopathology | Disease Progression | Kidney Failure, Chronic - therapy | Atherosclerosis - etiology | Renal Insufficiency, Chronic - therapy | Arterial Pressure | Atherosclerosis - therapy | Arteries - physiopathology | Kidney Failure, Chronic - complications | Aging | Vascular Stiffness
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5. Full Text Dissociation of Aortic Pulse Wave Velocity With Risk Factors for Cardiovascular Disease Other Than Hypertension: A Systematic Review
by Cecelja, Marina and Chowienczyk, Philip
Hypertension, ISSN 0194-911X, 12/2009, Volume 54, Issue 6, pp. 1328 - 1336
Carotid-femoral pulse wave velocity (cfPWV), a measure of large artery stiffness, is an important predictor of cardiovascular events. This has been attributed... 
Pulse wave velocity | Arteriosclerosis | Risk factors | Aortic stiffness | Atherosclerosis | atherosclerosis | INTIMA-MEDIA THICKNESS | risk factors | IMMUNODEFICIENCY-VIRUS-INFECTION | II TYPE-1 RECEPTOR | pulse wave velocity | arteriosclerosis | aortic stiffness | ISOLATED SYSTOLIC HYPERTENSION | LARGE ARTERY STIFFNESS | PERIPHERAL VASCULAR DISEASE | ASYMPTOMATIC YOUNG-ADULTS | LEFT-VENTRICULAR MASS | CHRONIC KIDNEY-DISEASE | CORONARY-HEART-DISEASE | STAGE RENAL-DISEASE | Aortic Diseases - physiopathology | Prognosis | Pulsatile Flow - physiology | Aortic Diseases - epidemiology | Atherosclerosis - physiopathology | Humans | Risk Factors | Hypertension - epidemiology | Aorta - physiology | Atherosclerosis - epidemiology | Blood Flow Velocity - physiology | Hypertension - physiopathology
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6. Full Text Aortic dilation in bicuspid aortic valve disease: Flow pattern is a major contributor and differs with valve fusion type
by Bissell, Malenka M and Hess, Aaron T and Biasiolli, Luca and Glaze, Steffan J and Loudon, Margaret and Pitcher, Alex and Davis, Anne and Prendergast, Bernard and Markl, Michael and Barker, Alex J and Neubauer, Stefan and Myerson, Saul G
Circulation: Cardiovascular Imaging, ISSN 1941-9651, 07/2013, Volume 6, Issue 4, pp. 499 - 507
Background Ascending aortic dilation is important in bicuspid aortic valve (BAV) disease, with increased risk of aortic dissection. We used cardiovascular MR... 
Aorta | Cardiac MRI | Wall shear stress | Vascular function | Bicuspid aortic valve | vascular function | WALL SHEAR-STRESS | CARDIAC & CARDIOVASCULAR SYSTEMS | cardiac MRI | bicuspid aortic valve | ELASTIC PROPERTIES | wall shear stress | aorta | NATURAL-HISTORY | BLOOD-FLOW | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Predictive Value of Tests | Prognosis | Prospective Studies | Heart Valve Diseases - pathology | Pulse Wave Analysis | Aortic Valve - abnormalities | Humans | Middle Aged | Elasticity | Stress, Mechanical | Male | Aortic Aneurysm - etiology | Case-Control Studies | Aortic Valve - pathology | Young Adult | Aneurysm, Dissecting - physiopathology | Cardiac-Gated Imaging Techniques - methods | Heart Valve Diseases - complications | Adult | Female | Aorta - physiopathology | Aortic Aneurysm - pathology | Imaging, Three-Dimensional | Vascular Stiffness | Dilatation, Pathologic | Aneurysm, Dissecting - etiology | Severity of Illness Index | Heart Valve Diseases - physiopathology | Cross-Sectional Studies | Models, Cardiovascular | Risk Factors | Aortic Aneurysm - physiopathology | Aortic Valve - physiopathology | Aneurysm, Dissecting - pathology | Chi-Square Distribution | Regional Blood Flow | Aorta - pathology | Magnetic Resonance Imaging | Analysis of Variance | Hemodynamics | cardiac magnetic resonance imaging
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7. Full Text Differential diagnosis and diagnostic flow chart of joint hypermobility syndrome/ehlers‐danlos syndrome hypermobility type compared to other heritable connective tissue disorders
by Colombi, Marina and Dordoni, Chiara and Chiarelli, Nicola and Ritelli, Marco
American Journal of Medical Genetics Part C: Seminars in Medical Genetics, ISSN 1552-4868, 03/2015, Volume 169, Issue 1, pp. 6 - 22
Joint hypermobility syndrome/Ehlers–Danlos syndrome hypermobility type (JHS/EDS‐HT) is an evolving and protean disorder mostly recognized by generalized joint... 
heritable connective tissue disorders | differential diagnosis | joint hypermobility syndrome | diagnostic flow chart | Ehlers–Danlos syndrome hypermobility type | Joint hypermobility syndrome | Diagnostic flow chart | Differential diagnosis | Ehlers-Danlos syndrome hypermobility type | Heritable connective tissue disorders | DE-NOVO MUTATION | FORM | MARFAN | THORACIC AORTIC-ANEURYSM | NATURAL-HISTORY | CLINICAL FINDINGS | GENETICS & HEREDITY | COMPOUND HETEROZYGOUS MUTATIONS | ARTERIAL-TORTUOSITY-SYNDROME | SYNDROME TYPE-IV | PEPTIDE DOMAIN | Osteogenesis Imperfecta - diagnosis | Humans | Marfan Syndrome - physiopathology | Skin Abnormalities - diagnosis | Ehlers-Danlos Syndrome - physiopathology | Skin Diseases, Genetic - diagnosis | Osteogenesis Imperfecta - physiopathology | Surveys and Questionnaires | Connective Tissue Diseases - physiopathology | Skin Abnormalities - physiopathology | Meningocele - physiopathology | Diagnosis, Differential | Joint Instability - diagnosis | Connective Tissue Diseases - diagnosis | Loeys-Dietz Syndrome - diagnosis | Loeys-Dietz Syndrome - physiopathology | Abnormalities, Multiple - physiopathology | Skin Diseases, Genetic - physiopathology | Abnormalities, Multiple - diagnosis | Arteries - physiopathology | Marfan Syndrome - diagnosis | Vascular Malformations - diagnosis | Ehlers-Danlos Syndrome - diagnosis | Joint Instability - physiopathology | Meningocele - diagnosis | Vascular Malformations - physiopathology | Arteries - abnormalities | Comparative analysis | Medical genetics
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8. Full Text Pulmonary Vascular Hemodynamic Response to Exercise in Cardiopulmonary Diseases
by Lewis, Gregory D and Bossone, Eduardo and Naeije, Robert and Grünig, Ekkehard and Saggar, Rajeev and Lancellotti, Patrizio and Ghio, Stefano and Varga, Janos and Rajagopalan, Sanjay and Oudiz, Ronald and Rubenfire, Melvyn
Circulation, ISSN 0009-7322, 09/2013, Volume 128, Issue 13, pp. 1470 - 1479
CARDIAC & CARDIOVASCULAR SYSTEMS | pulmonary circulation | VENTRICULAR SYSTOLIC FUNCTION | HEART-FAILURE | pulmonary | PRESERVED EJECTION FRACTION | SYSTEMIC-SCLEROSIS | exercise test | hemodynamics | TASK-FORCE | PERIPHERAL VASCULAR DISEASE | PHOSPHODIESTERASE-5 INHIBITION | AORTIC-VALVE-REPLACEMENT | GAS-EXCHANGE | hypertension | ARTERY PRESSURE RESPONSE | AIR-FLOW OBSTRUCTION | Heart Diseases - diagnosis | Animals | Lung Diseases - diagnosis | Heart Diseases - physiopathology | Exercise Test - methods | Humans | Exercise - physiology | Lung Diseases - physiopathology | Hemodynamics - physiology | Physiological aspects | Care and treatment | Exercise | Hemodynamics | Heart diseases | Analysis
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9. Full Text Left Ventricular Failure Produces Profound Lung Remodeling and Pulmonary Hypertension in Mice: Heart Failure Causes Severe Lung Disease
by Chen, Yingjie and Guo, Haipeng and Xu, Dachun and Xu, Xin and Wang, Huan and Hu, Xinli and Lu, Zhongbing and Kwak, Dongmin and Xu, Yawei and Gunther, Roland and Huo, Yuqing and Weir, E Kenneth
Hypertension, ISSN 0194-911X, 06/2012, Volume 59, Issue 6, pp. 1170 - 1178
Chronic left ventricular failure causes pulmonary congestion with increased lung weight and type 2 pulmonary hypertension. Understanding the molecular... 
Transverse aortic constriction | Pulmonary vascular morphology | Pulmonary hypertension | OVERLOAD | PRESSURE | HYPERTROPHY | OXIDATIVE STRESS | pulmonary hypertension | ARTERIAL-HYPERTENSION | transverse aortic constriction | PERIPHERAL VASCULAR DISEASE | EXTRACELLULAR-SUPEROXIDE DISMUTASE | EXPRESSION | pulmonary vascular morphology | Leukocytes - pathology | Lung Diseases - metabolism | Heart Failure - physiopathology | Hypertension, Pulmonary - physiopathology | Ventricular Dysfunction, Left - complications | Male | Pulmonary Edema - etiology | Lung Diseases - etiology | Pulmonary Edema - physiopathology | Collagen - genetics | Lung - metabolism | Pulmonary Edema - metabolism | Heart Failure - complications | Lung - pathology | Hypertrophy, Left Ventricular - metabolism | Mice, Inbred C57BL | Water - metabolism | Organ Size | Heart Failure - metabolism | Hypertension, Pulmonary - metabolism | Lung - physiopathology | Reverse Transcriptase Polymerase Chain Reaction | Constriction, Pathologic - complications | Blotting, Western | Ventricular Dysfunction, Left - physiopathology | Aorta - pathology | Ventricular Dysfunction, Left - metabolism | Collagen - metabolism | Animals | Transforming Growth Factor beta - genetics | Fibrosis - etiology | Hypertrophy, Left Ventricular - complications | Hypoxia - physiopathology | Lung Diseases - physiopathology | Mice | Hypertrophy, Left Ventricular - physiopathology | Hypertension, Pulmonary - etiology | Leukocytes - metabolism | Transforming Growth Factor beta - metabolism
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10. Full Text Two Decades Experience with Root Remodeling and Valve Repair for Bicuspid Aortic Valves
by Schneider, Ulrich, MD and Feldner, Susanne K., MD and Hofmann, Christopher and Schöpe, Jakob, M.Sc and Wagenpfeil, Stefan, PhD and Giebels, Christian, MD and Schäfers, Hans-Joachim, MD
Journal of Thoracic and Cardiovascular Surgery, The, ISSN 0022-5223, 2017, Volume 153, Issue 4, pp. S65 - S71
Abstract Objective Bicuspid aortic valve (BAV) anatomy is associated with ascending aortic aneurysm in approximately 50% of individuals; it may also lead to... 
Cardiothoracic Surgery | root remodeling | aortic root replacement | bicuspid aortic valve | aortic valve repair | REPLACEMENT | SURGERY | CARDIAC & CARDIOVASCULAR SYSTEMS | RESPIRATORY SYSTEM | RECONSTRUCTION | CONFIGURATION | DILATATION | Recurrence | Vascular Remodeling | Aortic Valve - abnormalities | Humans | Middle Aged | Cardiac Valve Annuloplasty - mortality | Male | Heart Valve Diseases - surgery | Aortic Aneurysm - etiology | Aortic Valve - surgery | Young Adult | Aneurysm, Dissecting - physiopathology | Time Factors | Aneurysm, Dissecting - surgery | Heart Valve Diseases - complications | Aortic Valve Stenosis - etiology | Aged, 80 and over | Heart Valve Diseases - mortality | Adult | Female | Pericardium - transplantation | Aortic Valve Stenosis - surgery | Retrospective Studies | Aorta - physiopathology | Cardiac Valve Annuloplasty - adverse effects | Child | Dilatation, Pathologic | Aneurysm, Dissecting - etiology | Heart Valve Diseases - physiopathology | Reoperation | Hospital Mortality | Aortic Aneurysm - mortality | Risk Factors | Aortic Aneurysm - physiopathology | Aortic Valve Stenosis - physiopathology | Aortic Aneurysm - surgery | Aortic Valve - physiopathology | Aortic Valve Insufficiency - physiopathology | Heart Valve Prosthesis Implantation - mortality | Treatment Outcome | Aortic Valve Insufficiency - etiology | Heart Valve Prosthesis Implantation - adverse effects | Aorta - surgery | Adolescent | Aortic Valve Insufficiency - surgery | Aged | Aortic Valve Insufficiency - mortality | Aneurysm, Dissecting - mortality | Aneurysms | Heart valve diseases | Epidemiology | Medical informatics | Health aspects
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11. Full Text Arterial stiffness, pressure and flow pulsatility and brain structure and function: the Age, Gene/Environment Susceptibility - Reykjavik Study
by Mitchell, Gary F and van Buchem, Mark A and Sigurdsson, Sigurdur and Gotal, John D and Jonsdottir, Maria K and Kjartansson, Ólafur and Garcia, Melissa and Aspelund, Thor and Harris, Tamara B and Gudnason, Vilmundur and Launer, Lenore J
Brain, ISSN 0006-8950, 11/2011, Volume 134, Issue 11, pp. 3398 - 3407
Aortic stiffness increases with age and vascular risk factor exposure and is associated with increased risk for structural and functional abnormalities in the... 
cognitive function | magnetic resonance imaging | aortic stiffness | brain structure | haemodynamics | INDEPENDENT PREDICTOR | PULSE-WAVE VELOCITY | COGNITIVE PERFORMANCE | AORTIC INPUT IMPEDANCE | RISK | NEUROSCIENCES | HYPERTENSIVE PATIENTS | CLINICAL NEUROLOGY | WHITE-MATTER LESIONS | ADVANCING AGE | SMALL-VESSEL DISEASE | CARDIOVASCULAR MORTALITY | Cardiovascular Diseases - physiopathology | Prospective Studies | Age Factors | Brain - physiopathology | Humans | Risk Factors | Male | Cardiovascular Diseases - pathology | Gene-Environment Interaction | Iceland | Brain - blood supply | Pulsatile Flow - physiology | Carotid Arteries - physiopathology | Vascular Stiffness - physiology | Aged, 80 and over | Brain - pathology | Female | Aged | Blood Pressure - physiology | Aorta - physiopathology | Blood Flow Velocity - physiology | Original
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