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Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 10/2017, Volume 37, Issue 12, pp. 2333 - 2341
OBJECTIVE—Angioplasty and stent implantation, the most common treatment for atherosclerotic lesions, have a significant failure rate because of restenosis.... 
Vascular smooth muscle cell proliferation | Cholesterol ester transfer protein | Angioplasty | Iliac artery | Apolipoprotein A-I | EFFLUX CAPACITY | cholesterol ester transfer protein | iliac artery | NEOINTIMAL HYPERPLASIA | ATHEROSCLEROSIS | RECEPTOR | apolipoprotein A-I | vascular smooth muscle cell proliferation | ENDOTHELIAL FUNCTION | HIGH-DENSITY-LIPOPROTEIN | HDL | HIGH-RISK | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | A-I | angioplasty | DRUG-ELUTING STENTS | Cholesterol Ester Transfer Proteins - antagonists & inhibitors | Iliac Artery - pathology | Iliac Artery - drug effects | Muscle, Smooth, Vascular - metabolism | Humans | Hyperplasia | Metals | Myocytes, Smooth Muscle - pathology | Iliac Artery - injuries | Angioplasty, Balloon - adverse effects | Prosthesis Design | Vascular System Injuries - pathology | Neointima | Time Factors | Iliac Artery - metabolism | Myocytes, Smooth Muscle - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Myocytes, Smooth Muscle - metabolism | Phosphatidylinositol 3-Kinase - metabolism | Stents | Disease Models, Animal | Muscle, Smooth, Vascular - drug effects | Rabbits | Cells, Cultured | Vascular System Injuries - etiology | Vascular System Injuries - prevention & control | Angioplasty, Balloon - instrumentation | Vascular System Injuries - metabolism | Muscle, Smooth, Vascular - injuries | Muscle, Smooth, Vascular - pathology | Animals | Carrier Proteins - metabolism | Signal Transduction - drug effects | Oxazolidinones - pharmacology | Cholesterol, HDL - blood | Cell Proliferation - drug effects | Scavenger Receptors, Class B - metabolism | Cholesterol Ester Transfer Proteins - metabolism | Anticholesteremic Agents - pharmacology | Apolipoprotein A-I - blood
Journal Article
Neurobiology of Disease, ISSN 0969-9961, 2009, Volume 34, Issue 3, pp. 525 - 534
Journal Article
American Journal of Physiology - Endocrinology and Metabolism, ISSN 0193-1849, 2015, Volume 308, Issue 4, pp. E283 - E293
The antileu-kemic agent asparaginase triggers the amino acid response (AAR) in the liver by activating the eukaryotic initiation factor 2 (eIF2) kinase general... 
General control nonderepressible 2 | Oxidative stress | Adipose | Amino acid response | Fibroblast growth factor 21 | Antithrombin III | Liver | Apolipoprotein B-100 | Mice | Eukaryotic initiation factor 2 | Steatosis | fibroblast growth factor 21 | eukaryotic initiation factor 2 | PHYSIOLOGY | liver | general control nonderepressible 2 | antithrombin III | adipose | ENDOPLASMIC-RETICULUM STRESS | APOLIPOPROTEIN-B | LIVER-DISEASE | mice | MAMMALIAN-CELLS | TRANSLATIONAL CONTROL | apolipoprotein B-100 | ACUTE LYMPHOBLASTIC-LEUKEMIA | ENDOCRINOLOGY & METABOLISM | GENE-EXPRESSION | steatosis | amino acid response | oxidative stress | AMINO-ACID DEPRIVATION | EIF2 KINASE GCN2 | Liver - pathology | Adipose Tissue, White - metabolism | Male | Antineoplastic Agents - administration & dosage | RNA, Messenger - metabolism | Escherichia coli Proteins - adverse effects | Asparaginase - adverse effects | Escherichia coli Proteins - administration & dosage | Liver - drug effects | Antineoplastic Agents - adverse effects | Lipid Peroxidation - drug effects | Female | Fibroblast Growth Factors - agonists | Homeostasis - drug effects | Chemical and Drug Induced Liver Injury - pathology | Protein-Serine-Threonine Kinases - metabolism | Biomarkers - metabolism | Adipose Tissue, White - pathology | Liver - metabolism | Mice, Inbred C57BL | Injections, Intraperitoneal | Protein-Serine-Threonine Kinases - genetics | Biomarkers - blood | Mice, Knockout | Triglycerides - metabolism | Asparaginase - administration & dosage | Gene Expression Regulation - drug effects | Animals | Chemical and Drug Induced Liver Injury - metabolism | Fibroblast Growth Factors - blood | Adipose Tissue, White - drug effects | Homeostasis | Fibroblast growth factors | Dosage and administration | Triglycerides | Health aspects | Protein kinases | Asparaginase
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 05/2012, Volume 32, Issue 22, pp. 7632 - 7645
Cholesterol is an essential membrane component enriched in plasma membranes, growth cones, and synapses. The brain normally synthesizes all cholesterol... 
SUBTYPE | LOCALIZATION | ACTIVATION | TRKB RECEPTORS | CNS SYNAPTOGENESIS | LIPID RAFTS | IN-VIVO | CENTRAL-NERVOUS-SYSTEM | HIPPOCAMPAL-NEURONS | NEUROSCIENCES | CELL-DEATH | Neural Pathways - drug effects | Neurites - physiology | Embryo, Mammalian | Humans | Cell Survival - genetics | Glial Fibrillary Acidic Protein - metabolism | RNA, Messenger - metabolism | Apolipoproteins E - metabolism | Microglia - physiology | Time Factors | Neurites - ultrastructure | Neural Pathways - embryology | Neurons - metabolism | Excitatory Postsynaptic Potentials - genetics | Neurites - drug effects | Animals, Newborn | Cell Survival - drug effects | Basic Helix-Loop-Helix Transcription Factors - genetics | Farnesyl-Diphosphate Farnesyltransferase - genetics | Tricarboxylic Acids - pharmacology | Neural Pathways - growth & development | Silver Staining | Mice, Transgenic | Signal Transduction - genetics | Mutation - genetics | Bridged Bicyclo Compounds, Heterocyclic - pharmacology | Patch-Clamp Techniques | Analysis of Variance | Signal Transduction - drug effects | Cerebral Cortex - growth & development | Cholesterol - pharmacology | Luminescent Proteins - genetics | Mice | Cholesterol - biosynthesis | Gene Expression Regulation, Developmental - genetics | Neurons - cytology | Cerebral Cortex - cytology | Excitatory Postsynaptic Potentials - drug effects | beta-Cyclodextrins - pharmacology | Cell Differentiation - genetics | Ephrin-A5 - pharmacology | Neurons - drug effects | Growth Cones - physiology | Anticholesteremic Agents | Microglia - drug effects | Bacterial Proteins - genetics | Cells, Cultured | Hippocampus - cytology | Nerve Tissue Proteins - genetics | Calcium-Calmodulin-Dependent Protein Kinase Type 2 - genetics | Nerve Tissue Proteins - metabolism | Animals | Cerebral Cortex - embryology | Cell Differentiation - drug effects | Apolipoproteins E - genetics | Neural Pathways - cytology | Bacterial Proteins - metabolism | Growth Cones - drug effects | Luminescent Proteins - metabolism
Journal Article
Circulation: Cardiovascular Quality and Outcomes, ISSN 1941-7713, 03/2010, Volume 3, Issue 2, pp. 196 - 203
Background-Exposure to tobacco smoke is associated with markers of preclinical atherosclerosis in adults, but its effect on arterial structure in adolescents... 
Passive smoking | Pediatrics | Apolipoproteins | Vasodilation | Atherosclerosis | atherosclerosis | FACTOR INTERVENTION PROJECT | apolipoproteins | CARDIAC & CARDIOVASCULAR SYSTEMS | MYOCARDIAL-INFARCTION | vasodilation | INFANCY-ONSET DIETARY | passive smoking | 11-YEAR-OLD HEALTHY-CHILDREN | ATHEROSCLEROSIS RISK | DENSITY-LIPOPROTEIN CHOLESTEROL | NUTRITION EXAMINATION SURVEY | pediatrics | 3RD NATIONAL-HEALTH | A-I | Carotid Artery, Common - diagnostic imaging | Prospective Studies | Tunica Media - drug effects | Humans | Endothelium, Vascular - drug effects | Male | Apolipoproteins B - blood | Chromatography, Gas | Aorta, Abdominal - drug effects | Atherosclerosis - etiology | Aorta, Abdominal - diagnostic imaging | Cotinine - blood | Time Factors | Atherosclerosis - diagnosis | Brachial Artery - physiopathology | Female | Tunica Intima - diagnostic imaging | Brachial Artery - drug effects | Child | Risk Assessment | Ultrasonography, Doppler | Atherosclerosis - physiopathology | Risk Factors | Endothelium, Vascular - physiopathology | Biomarkers - blood | Tunica Intima - drug effects | Tunica Media - diagnostic imaging | Tobacco Smoke Pollution - adverse effects | Endothelium, Vascular - diagnostic imaging | Carotid Artery, Common - drug effects | Adolescent | Finland | Vasodilation - drug effects | Longitudinal Studies | Atherosclerosis - prevention & control | Apolipoprotein A-I - blood | Smoking Cessation
Journal Article
Lancet, The, ISSN 0140-6736, 2010, Volume 376, Issue 9738, pp. 333 - 339
Summary Background HDL-cholesterol concentrations are inversely associated with occurrence of cardiovascular events. We addressed, using the JUPITER trial... 
Internal Medicine | MEDICINE, GENERAL & INTERNAL | ATHEROSCLEROSIS | PREVENTION | RANDOMIZED-TRIAL | TORCETRAPIB | TRIGLYCERIDES | PRAVASTATIN | HYPERCHOLESTEROLEMIA | CORONARY-HEART-DISEASE | A-I | HIGH-DENSITY-LIPOPROTEIN | Hydroxymethylglutaryl-CoA Reductase Inhibitors - administration & dosage | Myocardial Infarction - blood | Humans | Middle Aged | Male | Fluorobenzenes - administration & dosage | Angioplasty - statistics & numerical data | Incidence | C-Reactive Protein - metabolism | Adult | Cholesterol, LDL - blood | Female | Stroke - prevention & control | Double-Blind Method | Drug Administration Schedule | Pyrimidines - administration & dosage | Risk Factors | Rosuvastatin Calcium | Cholesterol, LDL - drug effects | Treatment Outcome | Biomarkers - blood | Stroke - blood | Sulfonamides - therapeutic use | Pyrimidines - therapeutic use | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Primary Prevention - methods | Angina, Unstable - prevention & control | Cholesterol, HDL - blood | Aged | Myocardial Infarction - prevention & control | Fluorobenzenes - therapeutic use | Sulfonamides - administration & dosage | Angina, Unstable - etiology | Complications and side effects | Hypercholesterolemia | Dosage and administration | Research | Cardiovascular diseases | Drug therapy | Risk factors | Statins | Fees & charges | Studies | Women | Heart attacks | Data collection | Cardiovascular disease | Apolipoproteins | Cholesterol
Journal Article
Gastroenterology, ISSN 0016-5085, 2012, Volume 142, Issue 3, pp. 634 - 643.e6
Background & Aims Hepatitis C virus (HCV) infection leads to progressive liver disease and is associated with a variety of extrahepatic syndromes, including... 
Gastroenterology and Hepatology | Virus Tropism | Neurologic Defect | HCVpp | HCVcc | ENTRY | RNA | CULTURE | APOLIPOPROTEIN-E | TRANSPORT | REPLICATION | TRANSCYTOSIS | LIVER | CENTRAL-NERVOUS-SYSTEM | GASTROENTEROLOGY & HEPATOLOGY | EXPRESSION | Immunohistochemistry | Liver - virology | Capillary Permeability | Receptors, Virus - metabolism | Humans | Middle Aged | Microvessels - metabolism | Hepacivirus - genetics | Microvessels - pathology | Hepacivirus - pathogenicity | Male | Case-Control Studies | Virus Internalization | Time Factors | HEK293 Cells | Viral Envelope Proteins - metabolism | Adult | Female | Hepatitis C - complications | Blood-Brain Barrier - virology | RNA, Viral - metabolism | Endothelial Cells - virology | Real-Time Polymerase Chain Reaction | Antiviral Agents - pharmacology | Viral Envelope Proteins - genetics | Endothelial Cells - metabolism | Microvessels - drug effects | Reverse Transcriptase Polymerase Chain Reaction | Virion - metabolism | Blood-Brain Barrier - drug effects | Blood-Brain Barrier - metabolism | Blood-Brain Barrier - pathology | Microscopy, Confocal | Virus Replication | Hepatitis C - mortality | Microvessels - virology | Hepatitis C - virology | Cell Line, Tumor | Endothelial Cells - pathology | Endothelial Cells - drug effects | Virus diseases | Molecular genetics | Low density lipoproteins | Immunodeficiency | Hepatitis C virus | HIV (Viruses) | Apolipoproteins | Health aspects | Endothelium
Journal Article
Atherosclerosis, ISSN 0021-9150, 2016, Volume 255, pp. 17 - 24
Journal Article
Journal of Alzheimer's Disease, ISSN 1387-2877, 2013, Volume 36, Issue 2, pp. 335 - 347
Journal Article
Biomedicine & Pharmacotherapy, ISSN 0753-3322, 2012, Volume 67, Issue 2, pp. 140 - 145
Abstract 2,3,5,4′-tetrahydroxystilbene-2-O-β-D-glucoside (TSG) extracted from Polygonum multiflorum (a traditional Chinese medicinal herb) has been proved to... 
Internal Medicine | Medical Education | Proteomic analysis | Atherosclerosis | 2,3,5,4′-tetrahydroxystilbene-2-O-β-D-glucoside (TSG) | 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside (TSG) | MEDICINE, RESEARCH & EXPERIMENTAL | MATRIX | OXIDATIVE STRESS | PROTEIN | CALRETICULIN | PROLIFERATION | 2,3,5,4 '-tetrahydroxystilbene-2-O-beta-D-glucoside (TSG) | ENDOTHELIAL-CELLS | PHARMACOLOGY & PHARMACY | SMOOTH-MUSCLE-CELLS | STATIN-INDUCED RHABDOMYOLYSIS | A-I | CORONARY-ARTERY-DISEASE | Proteome - genetics | Annexin A1 - genetics | Apoptosis - drug effects | Vimentin - metabolism | Atherosclerosis - genetics | Apoptosis - genetics | Male | Aorta - metabolism | Stilbenes - pharmacology | Calreticulin - genetics | Cholesterol - genetics | Apolipoprotein A-I - genetics | Inflammation - metabolism | Vimentin - genetics | Calreticulin - metabolism | Proteomics - methods | Cell Adhesion - genetics | Glucosides - pharmacology | Atherosclerosis - drug therapy | Aorta - drug effects | Rats | HSP70 Heat-Shock Proteins - genetics | Apolipoprotein A-I - metabolism | Proteome - analysis | Cell Adhesion - drug effects | Cholesterol - metabolism | Down-Regulation - drug effects | Rats, Sprague-Dawley | Atherosclerosis - metabolism | HSP70 Heat-Shock Proteins - metabolism | Gene Expression Regulation - drug effects | Up-Regulation - drug effects | Animals | Inflammation - genetics | Annexin A1 - metabolism | Proteome - metabolism | Ionization | Heat shock proteins | Apolipoproteins | Mass spectrometry | Intermediate filament proteins | Cholesterol
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 02/2010, Volume 30, Issue 2, pp. 246 - 252
OBJECTIVES—The apolipoprotein (apo)A-I mimetic peptide 5A is highly specific for ATP-binding cassette transporter (ABC)A1-mediated cholesterol efflux. We... 
HDL | Inflammation | Oxidation | Mimetic peptide | ApoA-I | OXIDATIVE STRESS | oxidation | RANDOMIZED CONTROLLED-TRIAL | inflammation | CORONARY ATHEROSCLEROSIS | REVERSE CHOLESTEROL TRANSPORT | ENDOTHELIAL-CELLS | NULL MICE | PERIPHERAL VASCULAR DISEASE | TNF-ALPHA | HEMATOLOGY | apoA-I | NADPH OXIDASES | mimetic peptide | HIGH-DENSITY-LIPOPROTEINS | Apolipoprotein A-I - pharmacology | Carotid Arteries - drug effects | Carotid Arteries - metabolism | Antioxidants - metabolism | Humans | NADPH Oxidases - metabolism | Male | NF-kappa B - metabolism | RNA, Messenger - metabolism | Anti-Inflammatory Agents - metabolism | Peptides - administration & dosage | Young Adult | Peptides - metabolism | ATP-Binding Cassette Transporters - genetics | RNA Interference | Time Factors | Carotid Artery Diseases - pathology | NADPH Oxidases - genetics | Anti-Inflammatory Agents - administration & dosage | Neutrophil Infiltration - drug effects | Disease Models, Animal | Rabbits | Anti-Inflammatory Agents - pharmacology | Endothelial Cells - metabolism | Apolipoprotein A-I - metabolism | Intercellular Adhesion Molecule-1 - metabolism | Signal Transduction - drug effects | Apolipoprotein A-I - administration & dosage | Vascular Cell Adhesion Molecule-1 - metabolism | Tumor Necrosis Factor-alpha - metabolism | Gene Expression Regulation, Enzymologic - drug effects | Lipoproteins, HDL - metabolism | Phosphatidylcholines - metabolism | Molecular Mimicry | Transfection | Superoxides - metabolism | ATP-Binding Cassette Transporters - metabolism | Adult | ATP Binding Cassette Transporter 1 | Carotid Artery Diseases - metabolism | Carotid Artery Diseases - drug therapy | Recombinant Proteins - metabolism | Cells, Cultured | Antioxidants - pharmacology | Peptides - pharmacology | Animals | Antioxidants - administration & dosage | Carotid Arteries - pathology | Endothelial Cells - drug effects
Journal Article
Clinical Therapeutics, ISSN 0149-2918, 2008, Volume 30, Issue 6, pp. 1089 - 1101
Journal Article