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JAMA, ISSN 0098-7484, 03/2012, Volume 307, Issue 12, pp. 1302 - 1309
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2012, Volume 7, Issue 1, pp. e29371 - e29371
We have recently identified conventional B2 cells as atherogenic and B1a cells as atheroprotective in hypercholesterolemic ApoE(-/-) mice. Here, we examined... 
IMMUNE | RESPONSES | VCAM-1 | ACTIVATING FACTOR BAFF | ENDOTHELIUM | BIOLOGY | IMMUNOGLOBULIN | T-CELL | ADHESION MOLECULES | POLARIZATION | LESIONS | Arteritis - genetics | Arteritis - pathology | Atherosclerosis - genetics | Male | Arteries - cytology | Arteries - metabolism | Endothelial Cells - classification | Inflammation Mediators - metabolism | Chemokine CCL2 - metabolism | B-Cell Activation Factor Receptor - genetics | Cytokines - genetics | Endothelial Cells - physiology | Atherosclerosis - pathology | Cytokines - metabolism | Endothelial Cells - metabolism | Mice, Inbred C57BL | Gene Expression Regulation | Arteritis - prevention & control | Atherosclerosis - complications | Chemokine CCL2 - genetics | Arteries - pathology | B-Cell Activation Factor Receptor - physiology | Atherosclerosis - metabolism | Mice, Knockout | Down-Regulation - physiology | Animals | Apolipoproteins E - genetics | Apolipoproteins E - physiology | Arteritis - complications | Cytoprotection - genetics | Mice | Endothelial Cells - pathology | Heart | Vascular cell adhesion molecule 1 | CD8 antigen | Body weight | Cardiovascular disease | Systematic review | Proliferating cell nuclear antigen | Aorta | Lupus | Spleen | Immunoglobulins | Cytokines | T cell receptors | Tumor necrosis factor-α | Gene expression | Apolipoproteins | Peritoneal fluid | Nursing | Arteriosclerosis | Weight reduction | Ligands | Monocyte chemoattractant protein 1 | Immunoglobulin M | Health sciences | Laboratories | Immunoglobulin G | Lipids | Lymphocytes T | Biology | Macrophages | Accumulation | Inflammatory diseases | Lymph nodes | High fat diet | Cell adhesion & migration | Lymphocytes | Apolipoprotein E | Rodents | Atherosclerosis | Interleukin 1 | Tumor necrosis factor-TNF | Lesions | Dendritic cells | Inflammation | CD4 antigen | Medicine | Lymphocytes B | BLyS protein | Bans | Diabetes | Fats and oils | Autoimmune diseases | Peritoneum | Index Medicus
Journal Article
Circulation, ISSN 0009-7322, 11/2012, Volume 126, Issue 19, pp. 2283 - 2292
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 06/2016, Volume 36, Issue 6, pp. 1174 - 1185
OBJECTIVE—Explore aorta B-cell immunity in aged apolipoprotein E-deficient (ApoE) mice. APPROACH AND RESULTS—Transcript maps, fluorescence-activated cell... 
atherosclerosis | B-lymphocytes | aging | germinal center | inflammation | REGULATORY FUNCTION | DEPLETION | LASER-CAPTURE MICRODISSECTION | ADAPTIVE IMMUNITY | LIVED PLASMA-CELLS | NULL MICE | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | AUTOIMMUNE-DISEASE | NZB/W MICE | HYPERCHOLESTEROLEMIC MICE | MAJOR SITE | Autoimmunity | Tertiary Lymphoid Structures - immunology | Apolipoproteins E - deficiency | Atherosclerosis - genetics | Autoantibodies - blood | Germinal Center - immunology | Transcriptome | Male | Aorta - metabolism | Aortic Diseases - metabolism | Aging - immunology | Aging - genetics | Immunoglobulins - blood | Plasma Cells - metabolism | B-Lymphocytes - metabolism | Aortic Diseases - pathology | Disease Models, Animal | Atherosclerosis - pathology | Genetic Predisposition to Disease | Atherosclerosis - immunology | Cytokines - metabolism | Signal Transduction | Aortic Diseases - immunology | Malondialdehyde - analogs & derivatives | Mice, Inbred C57BL | Gene Expression Regulation | Lymph Nodes - metabolism | Aorta - immunology | Lymph Nodes - immunology | Atherosclerosis - metabolism | Mice, Knockout | Tertiary Lymphoid Structures - pathology | Aorta - pathology | Aortic Diseases - genetics | Phenotype | Animals | B-Lymphocytes - immunology | Germinal Center - metabolism | Malondialdehyde - immunology | Apolipoproteins E - genetics | Tertiary Lymphoid Structures - metabolism | Immunologic Memory | Lipoproteins, LDL - immunology | Aging - metabolism | Plasma Cells - immunology | Index Medicus | 10195 | 10187 | 10188 | Basic Sciences
Journal Article
Circulation Research, ISSN 0009-7330, 06/2015, Volume 117, Issue 1, pp. e1 - e11
RATIONALE:Apolipoprotein E (apoE) exerts anti-inflammatory properties that protect against atherosclerosis and other inflammatory diseases. However, mechanisms... 
atherosclerosis | microRNAs | macrophages | apolipoproteins E | CARDIAC & CARDIOVASCULAR SYSTEMS | PERIPHERAL VASCULAR DISEASE | MIR-146A | APOE | ACCUMULATION | HEMATOLOGY | E-DEFICIENT MICE | EXPRESSION | PROMOTES | Transcription, Genetic - drug effects | Hyperlipidemias - genetics | Apolipoproteins E - deficiency | Atherosclerosis - genetics | Diet, High-Fat - adverse effects | Monocytes - metabolism | NF-kappa B - metabolism | Proto-Oncogene Proteins - biosynthesis | Trans-Activators - physiology | Atherosclerosis - etiology | Receptors, LDL - deficiency | Trans-Activators - genetics | MicroRNAs - agonists | Trans-Activators - biosynthesis | Hyperlipidemias - complications | NF-kappa B - antagonists & inhibitors | Lipopolysaccharides - toxicity | Specific Pathogen-Free Organisms | Hyperlipidemias - metabolism | Mice, Inbred C57BL | MicroRNAs - biosynthesis | Proto-Oncogene Proteins - genetics | Inflammation - etiology | Mice, Knockout | Monocytes - drug effects | Macrophages - metabolism | Animals | Apolipoproteins E - genetics | Proto-Oncogene Proteins - physiology | Apolipoproteins E - physiology | Inflammation - genetics | Macrophages - drug effects | Inflammation - prevention & control | Mice | MicroRNAs - genetics | MicroRNAs - physiology | Atherosclerosis - prevention & control | Index Medicus | apoE | miR-146a | microRNA | Atherosclerosis | NF-Kb
Journal Article
Circulation Research, ISSN 0009-7330, 01/2014, Volume 114, Issue 1, pp. 32 - 40
Journal Article
Journal Article
Molecules, ISSN 1420-3049, 2018, Volume 23, Issue 5, p. 1101
Atherosclerosis, a chronic inflammatory disease, is a major contributor to cardiovascular diseases. Ursolic acid (UA) is a phytonutrient with widely biological... 
LOX-1 | HUVECs | Atherosclerosis | ROS | Human Umbilical Vein Endothelial Cells | RNA, Small Interfering - genetics | Reactive Oxygen Species - metabolism | Triterpenes - pharmacology | Apolipoproteins E - deficiency | Atherosclerosis - genetics | Humans | Male | NF-kappa B - metabolism | Aorta - metabolism | Lipopolysaccharides - antagonists & inhibitors | Myeloid Differentiation Factor 88 - antagonists & inhibitors | Toll-Like Receptor 4 - antagonists & inhibitors | Disease Models, Animal | Atherosclerosis - pathology | NF-kappa B - antagonists & inhibitors | Atherosclerosis - drug therapy | Scavenger Receptors, Class E - genetics | Signal Transduction | Anti-Inflammatory Agents - pharmacology | Aorta - drug effects | Mice, Inbred C57BL | Gene Expression Regulation | Myeloid Differentiation Factor 88 - genetics | Toll-Like Receptor 4 - genetics | Inflammation | Scavenger Receptors, Class E - antagonists & inhibitors | Toll-Like Receptor 4 - metabolism | Atherosclerosis - metabolism | Mice, Knockout | Aorta - pathology | Scavenger Receptors, Class E - metabolism | Reactive Oxygen Species - antagonists & inhibitors | Animals | NF-kappa B - genetics | Apolipoproteins E - genetics | Lipopolysaccharides - pharmacology | Mice | Myeloid Differentiation Factor 88 - metabolism | RNA, Small Interfering - metabolism | Reactive oxygen species | Medical services | mRNA | Lipopolysaccharides | Proteins | Signal transduction | Biological effects | Atherogenic diet | Apolipoprotein E | Toll-like receptors | Aorta | Inhibition | Pretreatment | Heart diseases | NF-κB protein | Evaluation | Simvastatin | TLR4 protein | Gene expression | LOX-1 protein | Signaling | Acids | Liquid oxygen | Arteriosclerosis | MyD88 protein | In vivo methods and tests | Ursolic acid | Cardiovascular diseases | Index Medicus | atherosclerosis
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 10/2013, Volume 62, Issue 17, pp. 1575 - 1579
Journal Article
Diabetes, ISSN 0012-1797, 10/2009, Volume 58, Issue 10, pp. 2198 - 2210
Journal Article