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Journal Article
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 10/2012, Volume 32, Issue 43, pp. 15181 - 15192
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 03/2005, Volume 25, Issue 11, pp. 2803 - 2810
Journal Article
Journal Article
Journal Article
Journal Article
NATURE MEDICINE, ISSN 1078-8956, 05/2018, Volume 24, Issue 5, pp. 647 - 647
Efforts to develop drugs for Alzheimer's disease (AD) have shown promise in animal studies, only to fail in human trials, suggesting a pressing need to study... 
MEDICINE, RESEARCH & EXPERIMENTAL | PROTEIN | MEMORY DEFICITS | BIOCHEMISTRY & MOLECULAR BIOLOGY | TAU-PHOSPHORYLATION | CELL BIOLOGY | PLURIPOTENT STEM-CELLS | DEPENDENT IMPAIRMENT | IN-VIVO | GABAERGIC INTERNEURONS | FAMILIAL ALZHEIMERS-DISEASE | A-BETA ACCUMULATION | TRANSGENIC MICE | Cell Line | Small Molecule Libraries - pharmacology | Induced Pluripotent Stem Cells - drug effects | Humans | Cells, Cultured | GABAergic Neurons - drug effects | tau Proteins - metabolism | Apolipoprotein E3 - metabolism | Gene Editing | Nerve Degeneration - pathology | Alzheimer Disease - pathology | Homozygote | Protein Isoforms - metabolism | Apolipoprotein E4 - toxicity | Amyloid beta-Peptides - metabolism | Neurons - metabolism | GABAergic Neurons - metabolism | Phosphorylation - drug effects | Induced Pluripotent Stem Cells - cytology | Neurons - drug effects | Medical research | Neurons | Development and progression | Research | Apolipoproteins | Risk factors | Stem cells | Physiological aspects | Medicine, Experimental | Genetic aspects | Drug therapy | Alzheimer's disease | Health aspects | Apolipoprotein E4 | Phosphorylation | Molecular structure | Neurodegenerative diseases | Peptides | Toxicity | Stem cell transplantation | Molecular chains | γ-Aminobutyric acid | Tau protein | Apolipoprotein E | Amyloid | Degeneration | Alzheimers disease | Pluripotency | Genetic modification | Conformation | Index Medicus
Journal Article
Neuron, ISSN 0896-6273, 09/2017, Volume 96, Issue 1, pp. 115 - 129.e5
Diabetes and impaired brain insulin signaling are linked to the pathogenesis of Alzheimer’s disease (AD). The association between diabetes and AD-associated... 
Aggregation | Endosomal dysfunction | Alzheimer’s disease | Trafficking | Aging | APOE | Insulin signaling | Alzheimer's disease | DIABETES-MELLITUS | SKELETAL-MUSCLE | INTRANASAL INSULIN | GLUCOSE-METABOLISM | IMPROVES COGNITION | ALZHEIMERS-DISEASE | A-BETA | AMYLOID PRECURSOR PROTEIN | APOE-GENOTYPE | MILD COGNITIVE IMPAIRMENT | NEUROSCIENCES | Apolipoprotein E4 - genetics | Apolipoprotein E4 - metabolism | Insulin - physiology | Male | Mice, Transgenic | Neurons - cytology | Endosomes - metabolism | Mice, Knockout | Glycolysis - physiology | Apolipoprotein E3 - genetics | Animals | Aging - physiology | Insulin Resistance - physiology | Diet, High-Fat | Cell Respiration - physiology | Neurons - physiology | Female | Receptor, Insulin - metabolism | Mice | Neurons - metabolism | Primary Cell Culture | Mitochondria - physiology | Aging - metabolism | Insulin resistance | Apolipoproteins | Neurons | Insulin | Medical research | Medical colleges | Nervous system diseases | Neurosciences | Medicine, Experimental | Risk factors | Brain | Pathogenesis | Clinical trials | Nervous system | Glucose | Kinases | High fat diet | Signal transduction | Mitochondria | Apolipoprotein E | Rodents | Shinto | Amyloid | Protein transport | Age | Apolipoprotein E4 | Neurodegenerative diseases | Diabetes mellitus | Metabolism | Studies | Musculoskeletal system | Trapping | Glycolysis | Diabetes | Electron transport | Endosomes | Dementia | Index Medicus
Journal Article