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Nature (London), ISSN 1476-4687, 2012, Volume 485, Issue 7399, pp. 512 - 516
Journal Article
Biophysical Journal, ISSN 0006-3495, 02/2017, Volume 112, Issue 3, pp. 87a - 87a
Journal Article
The American Journal of Human Genetics, ISSN 0002-9297, 11/2009, Volume 85, Issue 5, pp. 628 - 642
Journal Article
Neurobiology of Disease, ISSN 0969-9961, 2014, Volume 64, pp. 150 - 162
Journal Article
Nature (London), ISSN 1476-4687, 2017, Volume 549, Issue 7673, pp. 523 - 527
APOE4 is the strongest genetic risk factor for late-onset Alzheimer disease. ApoE4 increases brain amyloid-beta pathology relative to other ApoE isoforms(1).... 
BRAIN ATROPHY | MICROGLIA | ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | FRONTOTEMPORAL DEMENTIA | IN-VIVO | FRONTAL-LOBE DEMENTIA | EPSILON-4 | ASSOCIATION | APOLIPOPROTEIN-E | TRANSGENIC MICE | Tumor Necrosis Factor-alpha - metabolism | Inflammation - pathology | Microglia - metabolism | Neurons - pathology | Phosphorylation | Apolipoprotein E4 - genetics | Tauopathies - genetics | Coculture Techniques | Humans | Tauopathies - pathology | tau Proteins - metabolism | Phosphoproteins - metabolism | Inflammation - metabolism | Microglia - immunology | tau Proteins - genetics | Apolipoprotein E4 - deficiency | Phosphoproteins - analysis | Apolipoprotein E4 - toxicity | Neurons - metabolism | Neurons - drug effects | Disease Models, Animal | Cell Survival - drug effects | Apolipoprotein E4 - metabolism | Genotype | Mice, Transgenic | Phosphoproteins - genetics | Immunity, Innate | Disease Progression | Gene Knock-In Techniques | Mice, Knockout | Tauopathies - metabolism | Animals | Alleles | Inflammation - genetics | Mice | Nervous system | Development and progression | Degeneration | Models | Apolipoproteins | Health aspects | Tau proteins | Brain | Pathogenesis | Genomes | Autophagy | Neuronal-glial interactions | Risk factors | Atrophy | Neurodegeneration | Apolipoprotein E | Rodents | Aging | Alzheimer's disease | Genotypes | Apolipoprotein E4 | Neurodegenerative diseases | Neurons | Health risks | Transgenic mice | Inflammation | Gene expression | Microglia | Pathology | Tau protein | Tumor necrosis factor | β-Amyloid | Alzheimers disease | Viability | Tumors | Dementia
Journal Article
Journal of molecular medicine (Berlin, Germany), ISSN 1432-1440, 2016, Volume 94, Issue 7, pp. 739 - 746
Apolipoprotein (apo) E was initially described as a lipid transport protein and major ligand for low density lipoprotein (LDL) receptors with a role in... 
Human Genetics | Biomedicine | Alzheimer’s disease | Atherosclerosis | Internal Medicine | Molecular Medicine | ApoE | Cholesterol | Small-molecule structure correctors | FAT TRANSPORT | MEDICINE, RESEARCH & EXPERIMENTAL | LDL RECEPTOR-BINDING | AMYLOID DEPOSITION | ALZHEIMERS-DISEASE | DOMAIN INTERACTION | LOW-DENSITY LIPOPROTEINS | DEPENDENT IMPAIRMENT | PLASMA-LIPOPROTEINS | GENETICS & HEREDITY | CENTRAL-NERVOUS-SYSTEM | INTEGRATED APPROACH | Alzheimer's disease | Phosphorylation | Apolipoprotein E4 - genetics | Lipoproteins, HDL - genetics | Humans | Lipoproteins, HDL - metabolism | tau Proteins - metabolism | Cardiovascular Diseases - pathology | Lipoproteins, LDL - genetics | Cardiovascular Diseases - genetics | tau Proteins - genetics | Lipoproteins, LDL - metabolism | Protein Interaction Domains and Motifs | Receptors, LDL - genetics | Apolipoprotein E4 - metabolism | Neurodegenerative Diseases - pathology | Cardiovascular Diseases - metabolism | Signal Transduction | Apolipoprotein E2 - genetics | Gene Expression Regulation | Models, Molecular | Receptors, LDL - metabolism | Neurodegenerative Diseases - genetics | Neurodegenerative Diseases - metabolism | Apolipoprotein E3 - metabolism | Cholesterol - metabolism | Apolipoprotein E2 - metabolism | Apolipoprotein E3 - genetics | Apolipoprotein E3 - chemistry | Apolipoprotein E4 - chemistry | Physiological aspects | Development and progression | Nervous system | Genetic aspects | Degeneration | Research | Cardiovascular diseases | Apolipoproteins | Index Medicus | Molecules in Medicine
Journal Article
DMM Disease Models and Mechanisms, ISSN 1754-8403, 03/2015, Volume 8, Issue 3, pp. 295 - 309
Journal Article
Cell metabolism, ISSN 1550-4131, 2017, Volume 26, Issue 5, pp. 719 - 737.e6
Journal Article