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Thrombosis and haemostasis, ISSN 0340-6245, 2014, Volume 111, Issue 3, pp. 518 - 530
Apart from transporting lipids through the body, the human plasma lipoproteins very low-density lipoprotein (VLDL) and low-density lipoprotein (LDL) are also... 
CETP | proteomics | atherothrombosis | LCAT | protein S | Apolipoproteins | coagulation | prenylcysteine oxidase | prothrombin | anti-microbial peptides | cathepcin D | nLC-MS/MS | dermicidin | TFPI-1 | lysozyme C | CD14 | PLTP | lipopolysaccharide binding protein | apoAV | Cardiovascular Biology and Cell Signalling | Prenylcysteine oxidase | Coagulation | Atherothrombosis | Cathepcin D | Lysozyme C | Lipopolysaccharide binding protein | Dermicidin | Antimicrobial peptides | Proteomics | Prothrombin | Protein S | ApoAV | Peripheral Vascular Disease | Life Sciences & Biomedicine | Hematology | Cardiovascular System & Cardiology | Science & Technology | Apolipoproteins A - metabolism | Humans | Antimicrobial Cationic Peptides - metabolism | Lipopolysaccharide Receptors - metabolism | Phospholipid Transfer Proteins - metabolism | Protein S - metabolism | Dyslipidemias - blood | Plasma - metabolism | Mass Spectrometry | Blood Coagulation | Lipoproteins - metabolism | Lipoproteins, LDL - metabolism | Prothrombin - metabolism | Apolipoprotein A-V | Computational Biology | Lipid Metabolism | Muramidase - metabolism | Cathepsin D - metabolism | Carbon-Sulfur Lyases - metabolism | Atherosclerosis - blood | Lipoproteins, VLDL - metabolism | Blood Coagulation Disorders - blood | Cholesterol Ester Transfer Proteins - metabolism | Proteome - metabolism | Phosphatidylcholine-Sterol O-Acyltransferase - metabolism
Journal Article
Immunity (Cambridge, Mass.), ISSN 1074-7613, 09/2017, Volume 47, Issue 3, pp. 566 - 581.e9
Microglia play a pivotal role in the maintenance of brain homeostasis but lose homeostatic function during neurodegenerative disorders. We identified a... 
Alzheimer’s disease | multiple sclerosis | transcriptional regulation | neurodegeneration | TREM2 | APOE | amyotrophic lateral sclerosis | microglia | Alzheimer's disease | Life Sciences & Biomedicine | Immunology | Science & Technology | Microglia - metabolism | Apolipoproteins E - deficiency | Membrane Glycoproteins - metabolism | Humans | Cerebral Cortex - pathology | Transcriptome | Apoptosis - genetics | Monocytes - metabolism | Gene Expression Profiling | Monocytes - immunology | Phagocytosis - genetics | Neurodegenerative Diseases - immunology | Apolipoproteins E - metabolism | Cerebral Cortex - metabolism | Alzheimer Disease - pathology | Microglia - immunology | Superoxide Dismutase-1 - metabolism | Amyloid beta-Peptides - metabolism | Amyloid beta-Protein Precursor - metabolism | Female | Neurons - metabolism | Disease Models, Animal | Gene Targeting | Plaque, Amyloid - pathology | Signal Transduction | Gene Expression Regulation | Phagocytosis - immunology | Immune Tolerance | Mice, Transgenic | Neurodegenerative Diseases - genetics | Neurodegenerative Diseases - metabolism | Mice, Knockout | Encephalomyelitis, Autoimmune, Experimental | Phenotype | Animals | Apoptosis - immunology | Apolipoproteins E - genetics | Alzheimer Disease - metabolism | Superoxide Dismutase-1 - genetics | Plaque, Amyloid - metabolism | Mice | Alzheimer Disease - genetics | Transforming Growth Factor beta - metabolism | Receptors, Immunologic - metabolism | Cluster Analysis | Nervous system diseases | Multiple sclerosis | Neurons | Analysis | Amyotrophic lateral sclerosis | Genetic aspects | Genetic transcription | Apolipoproteins | Brain | Animal models | Myeloid cells | Disease | Transcription | Neurodegenerative diseases | Genes | Homeostasis | Microglia | Neurological diseases | Proteins | Molecular modelling | Restoration | Neurodegeneration | Apolipoprotein E | Rodents | β-Amyloid | Plaques | Phagocytosis | Apoptosis | Index Medicus
Journal Article
Journal Article
American journal of physiology. Heart and circulatory physiology, ISSN 1522-1539, 02/2009, Volume 296, Issue 2, pp. H272 - H281
The farnesoid X receptor (FXR) is a member of the nuclear receptor superfamily that functions as an endogenous sensor for bile acids and regulates cholesterol and fatty acid metabolism... 
Nuclear receptor | Bile acids | Macrophages | Liver | Cardiac & Cardiovascular Systems | Physiology | Peripheral Vascular Disease | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Liver - pathology | ATP Binding Cassette Transporter, Sub-Family G, Member 1 | Apolipoproteins E - deficiency | Humans | Male | Aorta - metabolism | PPAR gamma - metabolism | RNA, Messenger - metabolism | Liver - drug effects | Interleukin-1beta - metabolism | Thiazolidinediones - pharmacology | Interleukin-6 - metabolism | Disease Models, Animal | Hyperlipidemias - immunology | Atherosclerosis - pathology | Atherosclerosis - immunology | Hyperlipidemias - metabolism | Liver - metabolism | Aorta - immunology | Receptors, Cytoplasmic and Nuclear - genetics | Toll-Like Receptor 4 - metabolism | Atherosclerosis - metabolism | Chenodeoxycholic Acid - analogs & derivatives | Cardiovascular Agents - pharmacology | Mice, Knockout | Aorta - pathology | Macrophages - metabolism | Hyperlipidemias - pathology | Ligands | Mice | Transcription Factors - agonists | Receptors, Cytoplasmic and Nuclear - metabolism | Tumor Necrosis Factor-alpha - metabolism | Receptors, Cytoplasmic and Nuclear - deficiency | Transcription Factors - deficiency | DNA-Binding Proteins - deficiency | CD36 Antigens - metabolism | DNA-Binding Proteins - agonists | Lipids - blood | ATP-Binding Cassette Transporters - metabolism | Chenodeoxycholic Acid - pharmacology | Female | ATP Binding Cassette Transporter 1 | Macrophages - immunology | Sterol Regulatory Element Binding Protein 1 - metabolism | Aorta - drug effects | Hyperlipidemias - drug therapy | Mice, Inbred C57BL | Receptors, Cytoplasmic and Nuclear - agonists | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Animals | Apolipoproteins E - genetics | PPAR gamma - agonists | Macrophages - drug effects | CD11b Antigen - metabolism | Atherosclerosis - prevention & control | T cell receptors | Gene expression | Rodents | Coronary vessels | Cells | Bile | Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 10/2003, Volume 278, Issue 44, pp. 42906 - 42912
Journal Article
American Journal of Physiology - Endocrinology And Metabolism, ISSN 0193-1849, 10/2010, Volume 299, Issue 4, pp. 584 - 592
Journal Article
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 02/2009, Volume 296, Issue 2, pp. 442 - 452
Platelet-derived growth factor (PDGF)-BB is a well-known smooth muscle (SM) cell (SMC) phenotypic modulator that signals by binding to PDGF αα-, αβ-, and... 
Shear stress | Disturbed blood flow | Smooth muscle α-actin | Smooth muscle myosin heavy chain | Cardiac & Cardiovascular Systems | Physiology | Peripheral Vascular Disease | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Up-Regulation | Phosphorylation | Apolipoproteins E - deficiency | Muscle, Smooth, Vascular - metabolism | Humans | Protein Multimerization | Actins - metabolism | Extracellular Signal-Regulated MAP Kinases - antagonists & inhibitors | Stress, Mechanical | Extracellular Signal-Regulated MAP Kinases - metabolism | RNA, Messenger - metabolism | Receptor, Platelet-Derived Growth Factor beta - genetics | Myosin Heavy Chains - metabolism | Platelet-Derived Growth Factor - genetics | Lymphokines - genetics | RNA Interference | Time Factors | Kruppel-Like Transcription Factors - metabolism | ets-Domain Protein Elk-1 - metabolism | Muscle Proteins - metabolism | Lymphokines - metabolism | Microfilament Proteins - metabolism | Myocytes, Smooth Muscle - drug effects | Myocytes, Smooth Muscle - metabolism | Genes, Reporter | Disease Models, Animal | Muscle, Smooth, Vascular - drug effects | Receptor, Platelet-Derived Growth Factor beta - metabolism | Calcium-Binding Proteins - metabolism | Recombinant Proteins - metabolism | Promoter Regions, Genetic | Atherosclerosis - physiopathology | Endothelial Cells - metabolism | Mice, Inbred C57BL | Cells, Cultured | Rats | Regional Blood Flow | Atherosclerosis - metabolism | Mice, Knockout | Phenotype | Platelet-Derived Growth Factor - metabolism | Animals | Apolipoproteins E - genetics | Mice | Protein Kinase Inhibitors - pharmacology | RNA, Small Interfering - metabolism | Proteins | Genotype & phenotype | Membranes | Arteriosclerosis | Genes | Ribonucleic acid--RNA | Cells | Index Medicus | shear stress | smooth muscle myosin heavy chain | smooth muscle α-actin | disturbed blood flow
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 05/2010, Volume 328, Issue 5985, pp. 1570 - 1573
Cholesterol metabolism is tightly regulated at the cellular level. Here we show that miR-33, an intronic microRNA (miRNA... 
MicroRNA | Hepatocytes | HDL lipoproteins | Liver | Genes | REPORTS | Homeostasis | Gene expression regulation | Macrophages | Cholesterols | Endothelial cells | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | ATP Binding Cassette Transporter, Sub-Family G, Member 1 | Membrane Glycoproteins - metabolism | Cholesterol, Dietary - administration & dosage | Lipoproteins - genetics | Lipoproteins, HDL - blood | Humans | Lipoproteins, HDL - metabolism | MicroRNAs - metabolism | Transfection | ATP-Binding Cassette Transporters - genetics | Dietary Fats - administration & dosage | Lipoproteins - metabolism | ATP-Binding Cassette Transporters - metabolism | Sterol Regulatory Element Binding Protein 2 - genetics | Sterol Regulatory Element Binding Protein 2 - metabolism | ATP Binding Cassette Transporter 1 | Cell Line | Introns | Liver - metabolism | Mice, Inbred C57BL | Gene Expression Regulation | Apolipoprotein A-I - metabolism | Cholesterol - metabolism | Membrane Glycoproteins - genetics | Proteins - genetics | Carrier Proteins - genetics | Macrophages - metabolism | Animals | Carrier Proteins - metabolism | Proteins - metabolism | Mice | MicroRNAs - genetics | Hypercholesterolemia - genetics | Macrophages, Peritoneal - metabolism | Hypercholesterolemia - metabolism | Physiological aspects | Control | Research | High density lipoproteins | Cholesterol metabolism | Lipoproteins | Cellular biology | Ribonucleic acid--RNA | Gene expression | Cholesterol | Index Medicus
Journal Article
Journal Article