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Publication DateClinical cancer research, ISSN 1078-0432, 05/2012, Volume 18, Issue 9, pp. 2502 - 2514
Life Sciences & Biomedicine | Oncology | Science & Technology | Biological and medical sciences | Medical sciences | Antineoplastic agents | Pharmacology. Drug treatments | Prospective Studies | Apoptosis - drug effects | Humans | Extracellular Signal-Regulated MAP Kinases - antagonists & inhibitors | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Immunoenzyme Techniques | Forkhead Transcription Factors - metabolism | Colony-Forming Units Assay | Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | Phthalic Acids - pharmacology | Proto-Oncogene Proteins c-akt - metabolism | Real-Time Polymerase Chain Reaction | Proto-Oncogene Proteins B-raf - metabolism | Membrane Proteins - genetics | Melanoma - pathology | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Apoptosis Regulatory Proteins - metabolism | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Indoles - adverse effects | Membrane Proteins - antagonists & inhibitors | Signal Transduction - drug effects | HSP90 Heat-Shock Proteins - antagonists & inhibitors | Cell Line, Tumor | HSP90 Heat-Shock Proteins - metabolism | Mice | Mice, Inbred BALB C | Forkhead Box Protein O3 | Azabicyclo Compounds - pharmacology | Phosphatidylinositol 3-Kinases - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Extracellular Signal-Regulated MAP Kinases - genetics | Proto-Oncogene Proteins c-akt - genetics | Proto-Oncogene Proteins c-bcl-2 - metabolism | Flow Cytometry | Bcl-2-Like Protein 11 | Apoptosis Regulatory Proteins - genetics | Membrane Proteins - metabolism | Forkhead Transcription Factors - antagonists & inhibitors | Melanoma - metabolism | Proto-Oncogene Proteins - metabolism | Proto-Oncogene Proteins - antagonists & inhibitors | RNA, Messenger - genetics | Proto-Oncogene Proteins - genetics | Forkhead Transcription Factors - genetics | Phosphatidylinositol 3-Kinases - genetics | Animals | Proto-Oncogene Proteins B-raf - genetics | Melanoma - drug therapy | Myeloid Cell Leukemia Sequence 1 Protein | Apoptosis Regulatory Proteins - antagonists & inhibitors | Fluorescent Antibody Technique | Sulfonamides - adverse effects | Proto-Oncogene Proteins c-bcl-2 - antagonists & inhibitors | Cell Proliferation - drug effects | Protein Kinase Inhibitors - pharmacology | Proto-Oncogene Proteins c-bcl-2 - genetics | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | Drug Resistance, Neoplasm - drug effects | Index Medicus
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Loading RightsNature communications, ISSN 2041-1723, 2016, Volume 7, Issue 1, pp. 10791 - 10791
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Immunohistochemistry | NLR Family, Pyrin Domain-Containing 3 Protein | Humans | Middle Aged | Child, Preschool | Male | Cystic Fibrosis - immunology | Young Adult | Calcium-Binding Proteins - immunology | Autophagy - genetics | Interleukin 1 Receptor Antagonist Protein - pharmacology | Child | Cytokines - genetics | Carrier Proteins - immunology | Disease Models, Animal | Apoptosis Regulatory Proteins - immunology | Interleukin 1 Receptor Antagonist Protein - immunology | Respiratory Mucosa - cytology | Cystic Fibrosis - microbiology | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Mice, Knockout | Cystic Fibrosis - genetics | Adolescent | Cystic Fibrosis Transmembrane Conductance Regulator - genetics | Mice | Aspergillus fumigatus | Calcium-Binding Proteins - genetics | Infant | Interleukin 1 Receptor Antagonist Protein - genetics | CARD Signaling Adaptor Proteins - genetics | Autophagy - immunology | Apoptosis Regulatory Proteins - genetics | Adult | Female | Pseudomonas aeruginosa | Lung - metabolism | Macrophages - immunology | Cytokines - immunology | In Situ Nick-End Labeling | CARD Signaling Adaptor Proteins - immunology | Cell Line | Enzyme-Linked Immunosorbent Assay | Mice, Inbred C57BL | Inflammation | Inflammasomes - genetics | Pseudomonas Infections - immunology | Carrier Proteins - genetics | Animals | Epithelial Cells - immunology | Inflammasomes - immunology | Fluorescent Antibody Technique | Polymorphism, Single Nucleotide | Aspergillosis - immunology | Index Medicus
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Loading RightsCancer research (Chicago, Ill.), ISSN 0008-5472, 04/2011, Volume 71, Issue 7, pp. 2750 - 2760
Life Sciences & Biomedicine | Oncology | Science & Technology | Tumors of the skin and soft tissue. Premalignant lesions | Dermatology | Pharmacology. Drug treatments | Biological and medical sciences | Medical sciences | Antineoplastic agents | Tumors | RNA, Small Interfering - genetics | Up-Regulation | Humans | Drug Resistance, Neoplasm | Phosphatidylinositol 3-Kinases - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Proto-Oncogene Proteins - biosynthesis | Bcl-2-Like Protein 11 | Melanoma - genetics | Apoptosis Regulatory Proteins - genetics | Indoles - pharmacology | Proto-Oncogene Proteins c-akt - metabolism | Proto-Oncogene Proteins B-raf - metabolism | Apoptosis Regulatory Proteins - biosynthesis | Melanoma - metabolism | Proto-Oncogene Proteins - antagonists & inhibitors | PTEN Phosphohydrolase - deficiency | Membrane Proteins - genetics | PTEN Phosphohydrolase - biosynthesis | Proto-Oncogene Proteins - genetics | Melanoma - pathology | Sulfonamides - pharmacology | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Membrane Proteins - biosynthesis | Membrane Proteins - antagonists & inhibitors | Proto-Oncogene Proteins B-raf - genetics | Melanoma - drug therapy | Apoptosis Regulatory Proteins - antagonists & inhibitors | Cell Line, Tumor | Protein Kinase Inhibitors - pharmacology | Apoptosis - physiology | Mutation | RNA, Small Interfering - administration & dosage | Index Medicus | PTEN | melanoma | BRAF | PLX4032 | therapy | resistance
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Loading RightsNature communications, ISSN 2041-1723, 07/2017, Volume 8, Issue 1, pp. 16078 - 16078
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Lung Neoplasms - drug therapy | Apoptosis - drug effects | Humans | Lung Neoplasms - metabolism | Myeloid Cell Leukemia Sequence 1 Protein - metabolism | Drug Resistance, Neoplasm | Molecular Targeted Therapy | Apoptosis Regulatory Proteins - drug effects | Myeloid Cell Leukemia Sequence 1 Protein - drug effects | Small Cell Lung Carcinoma - drug therapy | Small Cell Lung Carcinoma - metabolism | bcl-X Protein - drug effects | Proto-Oncogene Proteins c-bcl-2 - metabolism | bcl-X Protein - antagonists & inhibitors | Antineoplastic Agents - pharmacology | Myeloid Cell Leukemia Sequence 1 Protein - antagonists & inhibitors | Aniline Compounds - pharmacology | Cyclin-Dependent Kinase 9 - antagonists & inhibitors | Sulfonamides - pharmacology | Apoptosis Regulatory Proteins - metabolism | Drug Synergism | Pyridinium Compounds - pharmacology | Bridged Bicyclo Compounds, Heterocyclic - pharmacology | High-Throughput Screening Assays | Apoptosis Regulatory Proteins - antagonists & inhibitors | Proto-Oncogene Proteins c-bcl-2 - drug effects | Cell Line, Tumor | Proto-Oncogene Proteins c-bcl-2 - antagonists & inhibitors | Protein Kinase Inhibitors - pharmacology | bcl-X Protein - metabolism | Doxorubicin - pharmacology | Regulators | Bax protein | Bcl-2 protein | Small cell lung carcinoma | Lung cancer | High-throughput screening | Doxorubicin | BAK protein | Mcl-1 protein | Proteins | Mitochondria | Inhibitors | Bcl-x protein | Anthracycline | Addiction | Cell death | Sequestering | Cancer | Apoptosis | Index Medicus
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Interferon Regulatory Factor 4 Sustains CD8+ T Cell Expansion and Effector Differentiation
Immunity (Cambridge, Mass.), ISSN 1074-7613, 11/2013, Volume 39, Issue 5, pp. 833 - 845
Life Sciences & Biomedicine | Immunology | Science & Technology | CD8-Positive T-Lymphocytes - cytology | Cells, Cultured - cytology | Coculture Techniques | Dendritic Cells - immunology | T-Box Domain Proteins - biosynthesis | Interferon Regulatory Factors - deficiency | Bcl-2-Like Protein 11 | Interferon Regulatory Factors - physiology | Receptors, Antigen, T-Cell - immunology | TOR Serine-Threonine Kinases - physiology | Cell Differentiation | Proto-Oncogene Proteins - antagonists & inhibitors | Specific Pathogen-Free Organisms | Lymphocyte Activation | Mice, Inbred C57BL | Gene Expression Regulation | Interferon Regulatory Factors - genetics | Viral Plaque Assay | Mice, Transgenic | Transcription Factors - biosynthesis | Transcription Factors - genetics | T-Box Domain Proteins - genetics | Interferon Regulatory Factors - immunology | Animals | Membrane Proteins - antagonists & inhibitors | Apoptosis Regulatory Proteins - antagonists & inhibitors | Mice | Orthomyxoviridae Infections - virology | Orthomyxoviridae Infections - immunology | Apoptosis | Cyclin-Dependent Kinase Inhibitor Proteins - antagonists & inhibitors | Positive Regulatory Domain I-Binding Factor 1 | Transcription factors | Peptides | Lymphocytes | Rodents | T cell receptors | Infections | Expansion | Immune system | Index Medicus
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Loading RightsExperimental oncology, ISSN 1812-9269, 09/2012, Volume 34, Issue 3, pp. 200 - 211
Ubiquitin | RING | NF-kB | IAP | BIR | Smac | TNF | Apoptosis | Cancer | Neoplasms - metabolism | Signal Transduction | Mitochondrial Proteins - therapeutic use | Humans | Intracellular Signaling Peptides and Proteins - antagonists & inhibitors | Mitochondrial Proteins - antagonists & inhibitors | Neoplasm Proteins - antagonists & inhibitors | Intracellular Signaling Peptides and Proteins - metabolism | Molecular Targeted Therapy | Neoplasm Proteins - metabolism | Apoptosis Regulatory Proteins - metabolism | Neoplasms - drug therapy | X-Linked Inhibitor of Apoptosis Protein - antagonists & inhibitors | X-Linked Inhibitor of Apoptosis Protein - therapeutic use | Adaptor Proteins, Signal Transducing - antagonists & inhibitors | Mitochondrial Proteins - metabolism | Inhibitor of Apoptosis Proteins - antagonists & inhibitors | Apoptosis Regulatory Proteins - antagonists & inhibitors | X-Linked Inhibitor of Apoptosis Protein - metabolism | Intracellular Signaling Peptides and Proteins - therapeutic use | Inhibitor of Apoptosis Proteins - metabolism | Adaptor Proteins, Signal Transducing - metabolism | Apoptosis Regulatory Proteins - therapeutic use
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Scientific reports, ISSN 2045-2322, 02/2015, Volume 5, Issue 1, pp. 8202 - 8202
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Tumor Suppressor Protein p53 - antagonists & inhibitors | Apoptosis - drug effects | Humans | Piperazines - metabolism | Tumor Suppressor Protein p53 - genetics | Mebendazole - pharmacology | Cyclin-Dependent Kinase Inhibitor p21 - genetics | RNA Interference | Apoptosis Regulatory Proteins - genetics | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Antineoplastic Agents - pharmacology | Mebendazole - analogs & derivatives | Piperazines - antagonists & inhibitors | Proto-Oncogene Proteins c-mdm2 - antagonists & inhibitors | Proto-Oncogene Proteins c-mdm2 - metabolism | Neuroblastoma - pathology | bcl-2-Associated X Protein - genetics | Imidazoles - metabolism | Proto-Oncogene Proteins - metabolism | Proto-Oncogene Proteins - antagonists & inhibitors | Tumor Suppressor Protein p53 - metabolism | bcl-2-Associated X Protein - metabolism | Cyclin-Dependent Kinase Inhibitor p21 - antagonists & inhibitors | Proto-Oncogene Proteins - genetics | bcl-2-Associated X Protein - antagonists & inhibitors | Apoptosis Regulatory Proteins - metabolism | Animals | Signal Transduction - drug effects | Chickens | Apoptosis Regulatory Proteins - antagonists & inhibitors | Cell Line, Tumor | Imidazoles - antagonists & inhibitors | Neuroblastoma - metabolism | RNA, Small Interfering - metabolism | GTP-binding protein | MDM2 protein | Bax protein | Therapeutic applications | p53 Protein | RNA-mediated interference | Leukemia | siRNA | Neuroblastoma | Tumor cell lines | Drug resistance | Myeloma | Tubulin | Chorioallantoic membrane | Cancer | Apoptosis | Tumors | Index Medicus
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Loading RightsLeukemia, ISSN 0887-6924, 08/2007, Volume 21, Issue 8, pp. 1773 - 1782
Oncology | Life Sciences & Biomedicine | Hematology | Science & Technology | Hematologic and hematopoietic diseases | Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis | Biological and medical sciences | Medical sciences | Immunoprecipitation | Reactive Oxygen Species - metabolism | Apoptosis - drug effects | Humans | Transcriptional Activation | bcl-2 Homologous Antagonist-Killer Protein - genetics | Neoplasm Proteins - metabolism | RNA, Messenger - metabolism | bcl-2 Homologous Antagonist-Killer Protein - metabolism | Proto-Oncogene Proteins c-bcl-2 - metabolism | Cell Nucleus - metabolism | Bcl-2-Like Protein 11 | RNA Interference | Adaptor Proteins, Signal Transducing - antagonists & inhibitors | Apoptosis Regulatory Proteins - genetics | Membrane Proteins - metabolism | Tumor Cells, Cultured | Proto-Oncogene Proteins - metabolism | Cell Line | Proto-Oncogene Proteins - antagonists & inhibitors | Membrane Proteins - genetics | RNA, Messenger - genetics | bcl-2 Homologous Antagonist-Killer Protein - antagonists & inhibitors | Enzyme Inhibitors - pharmacology | Tumor Suppressor Protein p53 - metabolism | Proto-Oncogene Proteins - genetics | Blotting, Western | Leukemia, Lymphocytic, Chronic, B-Cell - pathology | Apoptosis Regulatory Proteins - metabolism | Membrane Proteins - antagonists & inhibitors | Leukemia, Lymphocytic, Chronic, B-Cell - metabolism | Myeloid Cell Leukemia Sequence 1 Protein | Adaptor Proteins, Signal Transducing - genetics | Apoptosis Regulatory Proteins - antagonists & inhibitors | Proto-Oncogene Proteins c-bcl-2 - antagonists & inhibitors | Histone Deacetylase Inhibitors | Leukemia, Lymphocytic, Chronic, B-Cell - drug therapy | Adaptor Proteins, Signal Transducing - metabolism | Proto-Oncogene Proteins c-bcl-2 - genetics | Usage | Care and treatment | Cancer cells | Histones | Research | Properties | Health aspects | Apoptosis | Cancer | Index Medicus
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Loading RightsOncotarget, ISSN 1949-2553, 2015, Volume 6, Issue 11, pp. 8722 - 8735
Hedgehog | PI3K | Rhabdomyosarcoma | Apoptosis | Oncology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Apoptosis - drug effects | Furans - pharmacology | Humans | Zinc Finger Protein Gli2 | Neoplasm Proteins - antagonists & inhibitors | Molecular Targeted Therapy | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | TOR Serine-Threonine Kinases - antagonists & inhibitors | Caspases - metabolism | Nuclear Proteins - biosynthesis | Amino Acid Chloromethyl Ketones - pharmacology | Apoptosis Regulatory Proteins - genetics | Rhabdomyosarcoma, Alveolar - pathology | TOR Serine-Threonine Kinases - physiology | Gene Expression Regulation, Neoplastic - drug effects | Neoplasm Proteins - genetics | Rhabdomyosarcoma, Embryonal - pathology | Apoptosis Regulatory Proteins - biosynthesis | Kruppel-Like Transcription Factors - biosynthesis | Neoplasm Proteins - biosynthesis | Transcription Factors - antagonists & inhibitors | Transcription Factors - biosynthesis | Proto-Oncogene Proteins c-akt - physiology | Hedgehog Proteins - antagonists & inhibitors | Pyrimidines - pharmacology | Chick Embryo | Drug Synergism | Animals | Signal Transduction - drug effects | Nuclear Proteins - antagonists & inhibitors | Cell Line, Tumor | Protein Kinase Inhibitors - pharmacology | Pyridines - pharmacology | Zinc Finger Protein GLI1 | Kruppel-Like Transcription Factors - antagonists & inhibitors | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | Drug Screening Assays, Antitumor | Index Medicus
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