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Biochemical and Biophysical Research Communications, ISSN 0006-291X, 03/2019, Volume 510, Issue 2, pp. 191 - 197
Iron is known to be a crucial regulator of glucose, and several studies have demonstrated that iron overload is one of the risk factors for insulin resistance... 
Iron overload | Irp2 knockout | Insulin resistance | Hyperglycemia | Oxidative stress and cell apoptosis | OVERLOAD | APOPTOSIS | OXIDATIVE STRESS | MITOCHONDRIAL FERRITIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | DAMAGE | DIABETES-MELLITUS | BIOPHYSICS | METABOLISM | DISEASE | LIVER | PROGRESSION | Glucose metabolism | RNA | Analysis | Liver | Muscles | Glucose | Dextrose | Blood proteins
Journal Article
Journal Article
Nature, ISSN 0028-0836, 10/2015, Volume 526, Issue 7575, pp. 666 - 671
Journal Article
Science, ISSN 0036-8075, 12/2010, Volume 330, Issue 6009, pp. 1390 - 1393
Although the proteins BAX and BAK are required for initiation of apoptosis at the mitochondria, how BAX and BAK are activated remains unsettled. We provide in... 
T lymphocytes | Mitochondria | Cytokines | Thymocytes | Neurons | Cell death | REPORTS | Cytochromes | Mice | Potassium | Apoptosis | NEURONAL APOPTOSIS | CYTOCHROME-C | MITOCHONDRIAL APOPTOSIS | MECHANISM | MULTIDISCIPLINARY SCIENCES | BH3 DOMAINS | RELEASE | JNK PATHWAY | PROTEINS | BCL-2 FAMILY-MEMBERS | MEMBRANE PERMEABILIZATION | BH3 Interacting Domain Death Agonist Protein - deficiency | T-Lymphocytes - physiology | bcl-2-Associated X Protein - chemistry | Protein Multimerization | Stress, Physiological | bcl-2 Homologous Antagonist-Killer Protein - genetics | BH3 Interacting Domain Death Agonist Protein - genetics | bcl-2 Homologous Antagonist-Killer Protein - metabolism | Membrane Proteins - deficiency | Caspases - metabolism | Bcl-2-Like Protein 11 | Apoptosis Regulatory Proteins - deficiency | Tumor Suppressor Proteins - deficiency | Tumor Suppressor Proteins - genetics | Neurons - physiology | Apoptosis Regulatory Proteins - genetics | Membrane Proteins - metabolism | BH3 Interacting Domain Death Agonist Protein - metabolism | bcl-2-Associated X Protein - genetics | Proto-Oncogene Proteins - metabolism | Tumor Suppressor Proteins - metabolism | Membrane Proteins - genetics | Cytochromes c - metabolism | Cells, Cultured | bcl-2-Associated X Protein - metabolism | Proto-Oncogene Proteins - genetics | Mitochondria - metabolism | Permeability | Proto-Oncogene Proteins - deficiency | Apoptosis Regulatory Proteins - metabolism | Mice, Knockout | Animals | Models, Biological | Cerebellum - cytology | Intracellular Membranes - metabolism | bcl-2 Homologous Antagonist-Killer Protein - chemistry | Protein research | Genetic aspects | Mitochondrial DNA | Biochemical genetics | Research | Properties | Methods | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 02/2016, Volume 530, Issue 7590, pp. 354 - 357
Journal Article
Journal Article
Nature, ISSN 0028-0836, 2012, Volume 490, Issue 7418, pp. 107 - 111
Detection of microbial products by host inflammasomes is an important mechanism of innate immune surveillance. Inflammasomes activate the caspase-1 (CASP1)... 
CYTOSOLIC PHOSPHOLIPASE A | FLAGELLIN | III SECRETION APPARATUS | MECHANISM | MICE DEFICIENT | MULTIDISCIPLINARY SCIENCES | NLRC4 INFLAMMASOME | INFECTION | PYROPTOSIS | CASPASE-1 ACTIVATION | IMMUNE RECOGNITION | Inflammation - pathology | Inflammasomes - metabolism | Hematocrit | Salmonella Infections - immunology | Eicosanoids - biosynthesis | Caspase 1 - metabolism | Male | Inflammation - metabolism | Time Factors | Flagellin - metabolism | Bacterial Toxins - genetics | Antigens, Bacterial - chemistry | Neuronal Apoptosis-Inhibitory Protein - deficiency | Macrophages, Peritoneal - immunology | Calcium-Binding Proteins - deficiency | Interleukin-1beta | Bacterial Toxins - chemistry | Apoptosis Regulatory Proteins - metabolism | Cyclooxygenase 1 - deficiency | Body Fluids - metabolism | Caspase 1 - deficiency | Recombinant Fusion Proteins - genetics | Cytosol - metabolism | Death | Mice | Antigens, Bacterial - metabolism | Capillary Permeability | Peritoneal Cavity | Legionella pneumophila | Intestines - metabolism | Antigens, Bacterial - genetics | Recombinant Fusion Proteins - metabolism | Peritoneal Lavage | Apoptosis Regulatory Proteins - deficiency | Flagellin - genetics | Female | Interleukin-18 | Calcium Signaling | Calcium-Binding Proteins - metabolism | Flagellin - immunology | Salmonella typhimurium - immunology | Mice, Inbred C57BL | Inflammation - immunology | Body Temperature | Neuronal Apoptosis-Inhibitory Protein - metabolism | Immunity, Innate - immunology | Bacterial Toxins - metabolism | Animals | Eicosanoids - metabolism | Fluid Shifts | Cellular signal transduction | Research | Properties | Bacterial proteins | Flagella (Microbiology) | Immune system | Proteins | Bone marrow | Pathology | Infections | Biosynthesis | Rodents | Index Medicus
Journal Article
Cell Reports, ISSN 2211-1247, 05/2013, Volume 3, Issue 5, pp. 1339 - 1345
Journal Article
Immunity, ISSN 1074-7613, 02/2008, Volume 28, Issue 2, pp. 206 - 217
Alterations in the stoichiometric balance between members of Bcl-2 and Fas apoptotic pathway could lead to the pathogenesis of systemic lupus erythematosus... 
MOLIMMUNO | APOPTOSIS | PROTEIN | B-CELL | DISEASE | NEGATIVE SELECTION | MURINE LUPUS | LUPUS-ERYTHEMATOSUS | IMMUNOLOGY | THYMOCYTES | T-CELLS | LPR | Autoimmunity | Kidney - pathology | Autoantibodies - blood | Humans | fas Receptor - deficiency | Kidney - immunology | Lupus Erythematosus, Systemic - metabolism | fas Receptor - metabolism | Membrane Proteins - deficiency | fas Receptor - immunology | Mice, Inbred MRL lpr | Bcl-2-Like Protein 11 | Apoptosis Regulatory Proteins - deficiency | Lupus Erythematosus, Systemic - immunology | Proto-Oncogene Proteins - immunology | fas Receptor - genetics | Apoptosis Regulatory Proteins - genetics | Membrane Proteins - metabolism | Macrophages - immunology | Proto-Oncogene Proteins - metabolism | Apoptosis Regulatory Proteins - immunology | Membrane Proteins - genetics | Lymphatic Diseases - immunology | Splenomegaly - immunology | Membrane Proteins - immunology | Proto-Oncogene Proteins - genetics | Proto-Oncogene Proteins - deficiency | Antigen-Presenting Cells - immunology | Apoptosis Regulatory Proteins - metabolism | Macrophage Activation | Animals | B-Lymphocytes - immunology | Lupus Erythematosus, Systemic - genetics | T-Lymphocytes - immunology | Mice | Lupus Erythematosus, Systemic - pathology | Apoptosis | Lupus | Development and progression | Systemic lupus erythematosus | Statistical analysis | Disease | Pathogenesis | Lymphocytes | Mortality | Arthritis | Autoimmune diseases | Gene expression | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 05/2006, Volume 441, Issue 7089, pp. 106 - 110
Journal Article