X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (84413) 84413
Newspaper Article (1602) 1602
Newsletter (741) 741
Book Chapter (256) 256
Book / eBook (28) 28
Dissertation (20) 20
Conference Proceeding (11) 11
Government Document (8) 8
Publication (8) 8
Book Review (5) 5
Magazine Article (5) 5
Reference (2) 2
Transcript (2) 2
Web Resource (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
apoptosis (70273) 70273
humans (49169) 49169
animals (37222) 37222
proteins (23572) 23572
cell biology (21204) 21204
mice (21185) 21185
gene expression (20318) 20318
oncology (20077) 20077
cancer (19823) 19823
expression (18766) 18766
female (15661) 15661
biochemistry & molecular biology (15191) 15191
cell line, tumor (14914) 14914
signal transduction (14652) 14652
male (14450) 14450
research (13821) 13821
kinases (13437) 13437
apoptosis - drug effects (12813) 12813
activation (11832) 11832
cell cycle (11745) 11745
genetic aspects (11494) 11494
cell proliferation (11324) 11324
research article (11249) 11249
medicine (10236) 10236
multidisciplinary sciences (10192) 10192
health aspects (9384) 9384
analysis (9377) 9377
tumors (9253) 9253
phosphorylation (9094) 9094
science (8469) 8469
genes (8370) 8370
cell death (8296) 8296
biology (8043) 8043
cell growth (7888) 7888
rodents (7511) 7511
oxidative stress (7502) 7502
physiological aspects (7502) 7502
apoptosis - genetics (7469) 7469
immunology (7358) 7358
inflammation (7075) 7075
cells (7015) 7015
proliferation (6897) 6897
metastasis (6631) 6631
mutation (6577) 6577
studies (6480) 6480
inhibition (6444) 6444
cells, cultured (6379) 6379
medicine, research & experimental (6358) 6358
development and progression (6222) 6222
care and treatment (6123) 6123
gene-expression (6028) 6028
growth (5988) 5988
rats (5988) 5988
apoptosis regulatory proteins - metabolism (5946) 5946
cell line (5894) 5894
apoptosis regulatory proteins - genetics (5849) 5849
gene expression regulation, neoplastic (5849) 5849
apoptosis - physiology (5817) 5817
biochemistry (5803) 5803
protein (5625) 5625
deoxyribonucleic acid--dna (5568) 5568
middle aged (5352) 5352
cancer therapies (5271) 5271
down-regulation (5239) 5239
physiology (5122) 5122
cytokines (5115) 5115
flow cytometry (5100) 5100
chemotherapy (5064) 5064
transcription factors (5061) 5061
micrornas - genetics (5056) 5056
breast cancer (5043) 5043
autophagy (5016) 5016
genetics & heredity (4976) 4976
micrornas (4973) 4973
cell proliferation - drug effects (4872) 4872
stem cells (4861) 4861
microrna (4836) 4836
gene (4810) 4810
cell survival (4800) 4800
mice, inbred c57bl (4778) 4778
mitochondria (4750) 4750
metabolism (4688) 4688
nf-kappa-b (4680) 4680
blotting, western (4617) 4617
transcription (4617) 4617
genetics (4476) 4476
rna (4436) 4436
adult (4422) 4422
transfection (4309) 4309
life sciences (4306) 4306
survival (4295) 4295
differentiation (4294) 4294
up-regulation (4293) 4293
signal transduction - drug effects (4227) 4227
medical prognosis (4209) 4209
p53 (4196) 4196
pathogenesis (4110) 4110
in-vitro (4105) 4105
death (4072) 4072
enzymes (4046) 4046
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Gerstein Science - Stacks (9) 9
Collection Dvlpm't (Acquisitions) - Vendor file (5) 5
Online Resources - Online (3) 3
Collection Dvlpm't (Acquisitions) - Closed Orders (2) 2
Engineering & Comp. Sci. - Stacks (1) 1
Sunnybrook Health Sciences Centre - Sunnybrook Stacks (1) 1
UofT at Scarborough - Stacks (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (86952) 86952
Chinese (261) 261
Japanese (191) 191
Portuguese (42) 42
French (30) 30
Russian (30) 30
German (27) 27
Norwegian (17) 17
Dutch (14) 14
Spanish (9) 9
Italian (8) 8
Polish (6) 6
Croatian (3) 3
Latvian (2) 2
Romanian (2) 2
Ukrainian (2) 2
Czech (1) 1
Hungarian (1) 1
Korean (1) 1
Swedish (1) 1
Turkish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


PLoS genetics, ISSN 1553-7404, 2013, Volume 9, Issue 5, p. e1003532
Journal Article
Developmental cell, ISSN 1534-5807, 2008, Volume 14, Issue 3, pp. 388 - 398
.... Here we identify the TEAD/TEF family protein Scalloped (Sd) as a DNA-binding transcription factor that partners with Yki to mediate the transcriptional output of the Hpo growth-regulatory pathway. The diap1 ( th... 
CELL CYCLE | SIGNALING | ORGAN SIZE | APOPTOSIS | GENE | WING FORMATION | FAT | TUMOR-SUPPRESSOR | EXPANDED ACT | CELL-PROLIFERATION | DEVELOPMENTAL BIOLOGY | BANTAM MICRORNA | DROSOPHILA | CELL BIOLOGY | Inhibitor of Apoptosis Proteins - genetics | Molecular Sequence Data | Drosophila - physiology | Trans-Activators - physiology | Drosophila Proteins - physiology | Wings, Animal - growth & development | Gene Expression Regulation, Developmental | Base Sequence | Trans-Activators - genetics | Transcription, Genetic | Nuclear Proteins - genetics | Intracellular Signaling Peptides and Proteins - genetics | Drosophila - genetics | Genes, Insect | Amino Acid Sequence | Transcription Factors - physiology | Signal Transduction | Animals, Genetically Modified | Protein-Serine-Threonine Kinases - physiology | Protein-Serine-Threonine Kinases - genetics | Organ Size - physiology | Gene Dosage | Binding Sites - genetics | DNA - metabolism | Transcription Factors - genetics | DNA - genetics | Sequence Homology, Amino Acid | Animals | Epistasis, Genetic | Models, Biological | Drosophila - growth & development | Nuclear Proteins - physiology | Drosophila Proteins - genetics | Mutation | Intracellular Signaling Peptides and Proteins - physiology | Growth | Genetic aspects | Genetic transcription
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2010, Volume 330, Issue 6009, pp. 1390 - 1393
Although the proteins BAX and BAK are required for initiation of apoptosis at the mitochondria, how BAX and BAK are activated remains unsettled... 
T lymphocytes | Mitochondria | Cytokines | Thymocytes | Neurons | Cell death | REPORTS | Cytochromes | Mice | Potassium | Apoptosis | NEURONAL APOPTOSIS | CYTOCHROME-C | MITOCHONDRIAL APOPTOSIS | MECHANISM | MULTIDISCIPLINARY SCIENCES | BH3 DOMAINS | RELEASE | JNK PATHWAY | PROTEINS | BCL-2 FAMILY-MEMBERS | MEMBRANE PERMEABILIZATION | BH3 Interacting Domain Death Agonist Protein - deficiency | T-Lymphocytes - physiology | bcl-2-Associated X Protein - chemistry | Protein Multimerization | Stress, Physiological | bcl-2 Homologous Antagonist-Killer Protein - genetics | BH3 Interacting Domain Death Agonist Protein - genetics | bcl-2 Homologous Antagonist-Killer Protein - metabolism | Membrane Proteins - deficiency | Caspases - metabolism | Bcl-2-Like Protein 11 | Apoptosis Regulatory Proteins - deficiency | Tumor Suppressor Proteins - deficiency | Tumor Suppressor Proteins - genetics | Neurons - physiology | Apoptosis Regulatory Proteins - genetics | Membrane Proteins - metabolism | BH3 Interacting Domain Death Agonist Protein - metabolism | bcl-2-Associated X Protein - genetics | Proto-Oncogene Proteins - metabolism | Tumor Suppressor Proteins - metabolism | Membrane Proteins - genetics | Cytochromes c - metabolism | Cells, Cultured | bcl-2-Associated X Protein - metabolism | Proto-Oncogene Proteins - genetics | Mitochondria - metabolism | Permeability | Proto-Oncogene Proteins - deficiency | Apoptosis Regulatory Proteins - metabolism | Mice, Knockout | Animals | Models, Biological | Cerebellum - cytology | Intracellular Membranes - metabolism | bcl-2 Homologous Antagonist-Killer Protein - chemistry | Protein research | Genetic aspects | Mitochondrial DNA | Biochemical genetics | Research | Properties | Methods
Journal Article
Nature cell biology, ISSN 1476-4679, 2009, Volume 11, Issue 6, pp. 739 - 746
...). Here we show that, in the absence of its ligand, Ptc interacts with the adaptor protein DRAL... 
PROTEIN | INHIBITION | GENE | MECHANISM | SONIC HEDGEHOG | NEURONAL DEATH | PRODUCT INDUCES APOPTOSIS | KAPPA-B | CASPASE ACTIVATION | CELL-DEATH | CELL BIOLOGY | RNA, Small Interfering - genetics | Caspase 9 - metabolism | Homeodomain Proteins - metabolism | Humans | Hedgehog Proteins - metabolism | Neoplasm Proteins - metabolism | CARD Signaling Adaptor Proteins - genetics | Multiprotein Complexes - metabolism | CARD Signaling Adaptor Proteins - metabolism | Hedgehog Proteins - genetics | Muscle Proteins - metabolism | Apoptosis Regulatory Proteins - genetics | Patched Receptors | Neoplasm Proteins - genetics | Cell Line | Receptors, Cell Surface - metabolism | Transcription Factors - genetics | Chick Embryo | Homeodomain Proteins - genetics | Apoptosis Regulatory Proteins - metabolism | Muscle Proteins - genetics | Transcription Factors - metabolism | Two-Hybrid System Techniques | Animals | Adaptor Proteins, Signal Transducing - genetics | LIM-Homeodomain Proteins | Signal Transduction - physiology | Apoptosis - physiology | Adaptor Proteins, Signal Transducing - metabolism | RNA, Small Interfering - metabolism | Receptors, Cell Surface - genetics | Causes of | Physiological aspects | Cell receptors | Research | Proteases | Apoptosis | Caspase 9 | Signal Transduction | Multiprotein Complexes | Receptors, Cell Surface | Cellular Biology | Hedgehog Proteins | Life Sciences | Muscle Proteins | Adaptor Proteins, Signal Transducing | Apoptosis Regulatory Proteins | Homeodomain Proteins | Neoplasm Proteins | CARD Signaling Adaptor Proteins | RNA, Small Interfering | Transcription Factors | Development Biology | physiology | genetics | metabolism
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 01/2013, Volume 110, Issue 5, pp. 1851 - 1856
A flagellin-independent caspase-1 activation pathway that does not require NAIP5 or NRLC4 is induced by the intracellular pathogen Legionella pneumophila. Here... 
Cytoskeletal Proteins | Flagellin | Immunoblotting | Legionella pneumophila | Macrophages | Adaptor Proteins, Vesicular Transport | Necrosis | Receptor, Interferon alpha-beta | Caspase 1 | Carrier Proteins | Calcium-Binding Proteins | Cytokines | Mice, Inbred C57BL | Cells, Cultured | Myeloid Differentiation Factor 88 | Mice, Knockout | Host-Pathogen Interactions | Animals | Apoptosis Regulatory Proteins | Bone Marrow Cells | Mice | Caspases | Enzyme Activation | Mutation | Apoptosis | Cell death | Innate immunity | Inflammasome | PATTERN-RECOGNITION | innate immunity | cell death | inflammasome | MULTIDISCIPLINARY SCIENCES | NLRP3 INFLAMMASOME ACTIVATION | INFECTION | RECEPTORS | Cytoskeletal Proteins - genetics | NLR Family, Pyrin Domain-Containing 3 Protein | Adaptor Proteins, Vesicular Transport - genetics | Caspase 1 - metabolism | Legionella pneumophila - genetics | Adaptor Proteins, Vesicular Transport - metabolism | Caspases - metabolism | Flagellin - genetics | Flagellin - metabolism | Apoptosis Regulatory Proteins - genetics | Cytoskeletal Proteins - metabolism | Receptor, Interferon alpha-beta - genetics | Macrophages - microbiology | Receptor, Interferon alpha-beta - metabolism | Calcium-Binding Proteins - metabolism | Cytokines - metabolism | Caspases - genetics | Myeloid Differentiation Factor 88 - genetics | Macrophages - cytology | Legionella pneumophila - metabolism | Apoptosis Regulatory Proteins - metabolism | Carrier Proteins - genetics | Macrophages - metabolism | Carrier Proteins - metabolism | Caspase 1 - genetics | CARD Signaling Adaptor Proteins | Bone Marrow Cells - microbiology | Legionella pneumophila - physiology | Myeloid Differentiation Factor 88 - metabolism | Bone Marrow Cells - metabolism | Calcium-Binding Proteins - genetics | Genetic aspects | Research | Properties | Immunological research | Biological Sciences
Journal Article
Journal Article
Nature cell biology, ISSN 1476-4679, 2015, Volume 17, Issue 10, pp. 1270 - 1281
.... Here, we present biochemical and genetic evidence that NOXA is a bona fide activator BH3... 
CYTOCHROME-C | MITOCHONDRIAL APOPTOSIS | ACTIVATION | CONFORMATIONAL-CHANGE | MEMBERS | PROAPOPTOTIC BAX | BH3 DOMAINS | PUMA | BH3-ONLY PROTEINS | MEMBRANE PERMEABILIZATION | CELL BIOLOGY | bcl-2 Homologous Antagonist-Killer Protein - genetics | Immunoblotting | BH3 Interacting Domain Death Agonist Protein - genetics | Cytochromes c - genetics | bcl-2 Homologous Antagonist-Killer Protein - metabolism | Embryo, Mammalian - metabolism | Proto-Oncogene Proteins c-bcl-2 - metabolism | Bcl-2-Like Protein 11 | Mitochondria - genetics | RNA Interference | Tumor Suppressor Proteins - genetics | Apoptosis Regulatory Proteins - genetics | Membrane Proteins - metabolism | BH3 Interacting Domain Death Agonist Protein - metabolism | bcl-2-Associated X Protein - genetics | Fibroblasts - metabolism | Proto-Oncogene Proteins - metabolism | Tumor Suppressor Proteins - metabolism | Membrane Proteins - genetics | Cytochromes c - metabolism | Mice, Inbred C57BL | Cells, Cultured | bcl-2-Associated X Protein - metabolism | Proto-Oncogene Proteins - genetics | Mitochondria - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Apoptosis Regulatory Proteins - metabolism | Mice, Knockout | Animals | Intestine, Small - cytology | Embryo, Mammalian - cytology | Models, Biological | Fibroblasts - cytology | Intestine, Small - metabolism | Proto-Oncogene Proteins c-bcl-2 - genetics | Apoptosis | Genotype | Genetic aspects | Properties | Cell death | Cellular control mechanisms
Journal Article
Nature communications, ISSN 2041-1723, 2016, Volume 7, Issue 1, p. 10791
.... Through basic and translational approaches involving murine models and human genetic epidemiology, we show here the importance of the different inflammasomes in regulating inflammatory responses... 
AIRWAY EPITHELIAL-CELLS | ASPERGILLUS-FUMIGATUS | III SECRETION APPARATUS | CHRONIC GRANULOMATOUS-DISEASE | ENVIRONMENT INTERACTIONS | MULTIDISCIPLINARY SCIENCES | NLRC4 INFLAMMASOME | HOST-DEFENSE | NLRP3 INFLAMMASOME | LUNG INFECTION | IMMUNE RECOGNITION | Immunohistochemistry | NLR Family, Pyrin Domain-Containing 3 Protein | Humans | Middle Aged | Child, Preschool | Male | Cystic Fibrosis - immunology | Young Adult | Calcium-Binding Proteins - immunology | Autophagy - genetics | Interleukin 1 Receptor Antagonist Protein - pharmacology | Child | Cytokines - genetics | Carrier Proteins - immunology | Disease Models, Animal | Apoptosis Regulatory Proteins - immunology | Interleukin 1 Receptor Antagonist Protein - immunology | Respiratory Mucosa - cytology | Cystic Fibrosis - microbiology | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Mice, Knockout | Cystic Fibrosis - genetics | Adolescent | Cystic Fibrosis Transmembrane Conductance Regulator - genetics | Mice | Aspergillus fumigatus | Calcium-Binding Proteins - genetics | Infant | Interleukin 1 Receptor Antagonist Protein - genetics | CARD Signaling Adaptor Proteins - genetics | Autophagy - immunology | Apoptosis Regulatory Proteins - genetics | Adult | Female | Pseudomonas aeruginosa | Lung - metabolism | Macrophages - immunology | Cytokines - immunology | In Situ Nick-End Labeling | CARD Signaling Adaptor Proteins - immunology | Cell Line | Enzyme-Linked Immunosorbent Assay | Mice, Inbred C57BL | Inflammation | Inflammasomes - genetics | Pseudomonas Infections - immunology | Carrier Proteins - genetics | Animals | Epithelial Cells - immunology | Inflammasomes - immunology | Fluorescent Antibody Technique | Polymorphism, Single Nucleotide | Aspergillosis - immunology
Journal Article
The Journal of biological chemistry, ISSN 1083-351X, 2016, Volume 291, Issue 13, pp. 6689 - 6695
Intrinsically disordered proteins (IDPs) are characterized by a lack of persistent structure... 
signaling | residual structure | electrostatics | coupled folding and binding | BIOCHEMISTRY & MOLECULAR BIOLOGY | protein electrostatics | C-MYB | TRANSITION-STATE | INDUCED FIT | protein-protein interactions | INTRINSICALLY DISORDERED PROTEINS | LINEAGE LEUKEMIA PROTEIN | IDP | MOLECULAR RECOGNITION | KIX DOMAIN | SEQUENCE | protein folding | phi-value | TRANSACTIVATION DOMAIN | kinetics | biophysics | protein dynamic | CONFORMATIONAL SELECTION | Cyclic AMP Response Element-Binding Protein - chemistry | Humans | Myeloid Cell Leukemia Sequence 1 Protein - metabolism | CREB-Binding Protein - chemistry | Proto-Oncogene Proteins - chemistry | CREB-Binding Protein - genetics | CREB-Binding Protein - metabolism | Thermodynamics | Apoptosis Regulatory Proteins - genetics | Myeloid Cell Leukemia Sequence 1 Protein - chemistry | Protein Interaction Domains and Motifs | Proto-Oncogene Proteins - metabolism | Signal Transduction | Apoptosis Regulatory Proteins - chemistry | Proto-Oncogene Proteins - genetics | Static Electricity | Intrinsically Disordered Proteins - genetics | Molecular Dynamics Simulation | Myeloid Cell Leukemia Sequence 1 Protein - genetics | Protein Folding | Apoptosis Regulatory Proteins - metabolism | Cyclic AMP Response Element-Binding Protein - genetics | Intrinsically Disordered Proteins - chemistry | Cyclic AMP Response Element-Binding Protein - metabolism | Hydrophobic and Hydrophilic Interactions | Protein Binding | Kinetics | Intrinsically Disordered Proteins - metabolism | Minireviews
Journal Article
PLoS genetics, ISSN 1553-7404, 2011, Volume 7, Issue 4, p. e1002046
Journal Article