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Bioorganic chemistry, ISSN 0045-2068, 10/2018, Volume 80, p. 174
Journal Article
Nature nanotechnology, ISSN 1748-3387, 12/2019, Volume 14, Issue 12, pp. 1150 - 1159
Science & Technology - Other Topics | Materials Science | Nanoscience & Nanotechnology | Technology | Materials Science, Multidisciplinary | Science & Technology | Cell Line | Chronic Pain - drug therapy | Aprepitant - administration & dosage | Humans | Mice, Inbred C57BL | Neurokinin-1 Receptor Antagonists - therapeutic use | Rats | Male | Neurokinin-1 Receptor Antagonists - administration & dosage | Endosomes - metabolism | Drug Delivery Systems | Chronic Pain - metabolism | Delayed-Action Preparations - metabolism | Neurokinin-1 Receptor Antagonists - pharmacokinetics | Animals | Nanoparticles - metabolism | HEK293 Cells | Receptors, Neurokinin-1 - metabolism | Aprepitant - pharmacokinetics | Aprepitant - therapeutic use | Hydrogen-Ion Concentration | Clathrin | Drug delivery systems | Pain perception | Substance P | Acidification | Drug delivery | Inflammation | pH effects | Nanoparticles | Endocytosis | Pain | Neurokinin NK1 receptors | Neurokinin | Opioids | Dynamin | Endosomes | Index Medicus
Journal Article
Annals of oncology, ISSN 0923-7534, 2016, Volume 27, Issue suppl 5, pp. v119 - v133
Journal Article
Gastroenterology (New York, N.Y. 1943), ISSN 0016-5085, 01/2018, Volume 154, Issue 1, pp. 65 - 76.e11
RCT | Chronic Nausea and Vomiting | Gastroparesis | Aprepitant Treatment | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Aprepitant | Double-Blind Method | Humans | Middle Aged | Gastroparesis - complications | Male | Treatment Outcome | Nausea - prevention & control | Nausea - etiology | Antiemetics - therapeutic use | Vomiting - etiology | Adult | Female | Chronic Disease | Vomiting - prevention & control | Morpholines - therapeutic use | Care and treatment | Analysis | Nausea | Index Medicus | Abridged Index Medicus | chronic nausea and vomiting | aprepitant treatment
Journal Article
Scientific reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 14169 - 10
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Humans | Neurokinin-1 Receptor Antagonists - metabolism | Neurokinin A - metabolism | Neurokinin-1 Receptor Antagonists - pharmacology | Pharmaceutical Preparations - metabolism | Aprepitant - metabolism | Signal Transduction - drug effects | Receptors, Neurokinin-1 - agonists | Cell Line, Tumor | Receptors, Neurokinin-1 - metabolism | Substance P - metabolism | Aprepitant - analogs & derivatives | Kinetics | Aprepitant - pharmacology | Signal transduction | Antagonists | Drug discovery | Index Medicus
Journal Article
American journal of health-system pharmacy, ISSN 1079-2082, 12/2017, Volume 74, Issue 24, p. 2026
Journal Article
Nature communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 638 - 638
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Magnetic Resonance Spectroscopy - methods | Aprepitant - metabolism | Aprepitant - chemistry | Humans | Crystallography - methods | Receptors, Neurokinin-1 - chemistry | Protein Binding | Receptors, Neurokinin-1 - metabolism | Substance P | Amino acids | Nausea | Antagonists | Drug development | Crystallography | X-ray crystallography | Magnetic resonance spectroscopy | Signaling | Chemotherapy | Vomiting | Neurokinin NK1 receptors | Neurokinin | Ligands | NMR spectroscopy | Binding sites | Crystal structure | Conformation | Index Medicus
Journal Article
Future oncology (London, England), ISSN 1479-6694, 11/2018, Volume 14, Issue 27, pp. 2849 - 2859
aprepitant | safety | antiemetics | Life Sciences & Biomedicine | Oncology | Science & Technology | Dyspnea - chemically induced | Nausea - chemically induced | Aprepitant - administration & dosage | Humans | Middle Aged | Antiemetics - administration & dosage | Male | Healthy Volunteers | Young Adult | Antineoplastic Agents - adverse effects | Adult | Antiemetics - adverse effects | Female | Nausea - drug therapy | Aprepitant - adverse effects | Morpholines - adverse effects | Neurokinin-1 Receptor Antagonists - adverse effects | Morpholines - administration & dosage | Neurokinin-1 Receptor Antagonists - administration & dosage | Treatment Outcome | Vomiting - drug therapy | Dyspnea - epidemiology | Neoplasms - drug therapy | Cross-Over Studies | Vomiting - chemically induced | Infusions, Intravenous
Journal Article
Indian journal of medical and paediatric oncology, ISSN 0971-5851, 4/2019, Volume 40, Issue 2, pp. 279 - 281
Journal Article
Bone marrow transplantation (Basingstoke), ISSN 0268-3369, 08/2018, Volume 53, Issue 8, pp. 1010 - 1018
Immunology | Life Sciences & Biomedicine | Hematology | Oncology | Transplantation | Biophysics | Science & Technology | Prospective Studies | Nausea - chemically induced | Humans | Middle Aged | Male | Vomiting - drug therapy | Cyclophosphamide - adverse effects | Young Adult | Vomiting - chemically induced | Pilot Projects | Antiemetics - therapeutic use | Hematopoietic Stem Cell Transplantation - adverse effects | Adult | Female | Transplantation Conditioning - adverse effects | Hematopoietic Stem Cell Transplantation - methods | Transplantation Conditioning - methods | Nausea - drug therapy | Aprepitant - therapeutic use | Antiemetics - pharmacology | Aprepitant - pharmacology | Aprepitant | Prevention | Complications and side effects | Cyclophosphamide | Vomiting | Dosage and administration | Nausea | Hematopoietic stem cells | Methods | Antiemetics and antinauseants | Dexamethasone | Transplants & implants | Stem cell transplantation | Patients | Hemopoiesis | Chemotherapy | Randomization | Stem cells | Standard deviation | Conditioning | Index Medicus
Journal Article
Nature communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 17 - 11
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Receptors, Neurokinin-1 - isolation & purification | Recombinant Proteins - metabolism | Neurokinin-1 Receptor Antagonists - chemistry | Piperidines - chemistry | Protein Structure, Secondary | Pyridines - chemistry | Humans | Recombinant Proteins - chemistry | Crystallography, X-Ray | Structure-Activity Relationship | Molecular Dynamics Simulation | Recombinant Proteins - isolation & purification | Neurokinin-1 Receptor Antagonists - pharmacology | Piperidines - pharmacology | Aprepitant - chemistry | Drug Design | HEK293 Cells | Receptors, Neurokinin-1 - chemistry | Receptors, Neurokinin-1 - metabolism | Pyridines - pharmacology | Binding Sites | Aprepitant - pharmacology | Proteins | High resolution | Peptides | Neurokinin | Neurokinin NK1 receptors | Crosslinking | Helices | Antagonists | Crystal structure | Index Medicus
Journal Article
Expert opinion on drug safety, ISSN 1474-0338, 02/2020, Volume 19, Issue 2, pp. 205 - 210
Aprepitant | HTX-019 | Intravenous push | fosaprepitant | safety | neurokinin 1 receptor antagonist | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Injections, Intravenous | Nausea - chemically induced | Aprepitant - administration & dosage | Humans | Middle Aged | Antiemetics - administration & dosage | Male | Antineoplastic Agents - administration & dosage | Antineoplastic Agents - adverse effects | Aged, 80 and over | Adult | Antiemetics - adverse effects | Female | Retrospective Studies | Drug Therapy, Combination | Aprepitant - adverse effects | Vomiting - prevention & control | Dexamethasone - administration & dosage | Neurokinin-1 Receptor Antagonists - adverse effects | Ondansetron - administration & dosage | Neurokinin-1 Receptor Antagonists - administration & dosage | Palonosetron - administration & dosage | Neoplasms - drug therapy | Nausea - prevention & control | Vomiting - chemically induced | Aged | Infusions, Intravenous | Index Medicus
Journal Article
The Journal of supercritical fluids, ISSN 0896-8446, 10/2018, Volume 140, pp. 72 - 84
Nanoparticles | Aprepitant (chemotherapy drug) | Anticancer drug | Dissolution rate enhancement | Solubility | RESS-SC | Engineering | Physical Sciences | Engineering, Chemical | Chemistry | Technology | Chemistry, Physical | Science & Technology | Aprepitant | Chemotherapy | Nanotechnology | Cancer
Journal Article