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animals (484) 484
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apyrase - metabolism (347) 347
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apyrase (241) 241
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atp (122) 122
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Genes and Development, ISSN 0890-9369, 10/2016, Volume 30, Issue 19, pp. 2187 - 2198
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 2724 - 13
Identifying tumor antigen-specific T cells from cancer patients has important implications for immunotherapy diagnostics and therapeutics. Here, we show that... 
TGF-BETA | MELANOMA | THERAPY | MEMORY | CANCER REGRESSION | INFILTRATING LYMPHOCYTES | MULTIDISCIPLINARY SCIENCES | PD-1 | EXPRESSION | EXHAUSTION | ANTIGEN | Antigens, CD - immunology | CD8-Positive T-Lymphocytes - pathology | Adenocarcinoma of Lung - pathology | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - pathology | Humans | Squamous Cell Carcinoma of Head and Neck - pathology | Ovarian Neoplasms - pathology | Transcriptome | Male | Receptors, Antigen, T-Cell, alpha-beta - immunology | Squamous Cell Carcinoma of Head and Neck - mortality | Ovarian Neoplasms - mortality | Antigens, CD - genetics | Squamous Cell Carcinoma of Head and Neck - immunology | Ovarian Neoplasms - genetics | Adenocarcinoma of Lung - mortality | Adenocarcinoma of Lung - genetics | Carcinoma, Squamous Cell - mortality | Melanoma - genetics | Integrin alpha Chains - immunology | Female | Adenocarcinoma of Lung - immunology | Apyrase - immunology | Immunophenotyping | Melanoma - pathology | Carcinoma, Squamous Cell - immunology | Receptors, Antigen, T-Cell, alpha-beta - genetics | CD8 Antigens - immunology | Squamous Cell Carcinoma of Head and Neck - genetics | Lymphocytes, Tumor-Infiltrating - pathology | Melanoma - immunology | Apyrase - genetics | CD8 Antigens - genetics | Survival Analysis | CD8-Positive T-Lymphocytes - immunology | Integrin alpha Chains - genetics | Lymphocytes, Tumor-Infiltrating - immunology | Melanoma - mortality | Ovarian Neoplasms - immunology | Head | Phenotypes | Tumor cells | CD8 antigen | T cell receptors | Lymphocytes T | Patients | Metastases | T-cell receptor | CD103 antigen | Major histocompatibility complex | Lymphocytes | Immunotherapy | Head and neck cancer | Neck | Solid tumors | Cancer | Tumors | BASIC BIOLOGICAL SCIENCES
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 09/2012, Volume 122, Issue 9, pp. 3063 - 3087
Amyotrophic lateral sclerosis (ALS) is a progressive disease associated with neuronal cell death that is thought to involve aberrant immune responses. Here we... 
BREAST-CANCER | MEDICINE, RESEARCH & EXPERIMENTAL | INHERITED ALS | DENDRITIC CELLS | SIGNALING PATHWAY | REGULATORY T-CELLS | CENTRAL-NERVOUS-SYSTEM | AMYOTROPHIC-LATERAL-SCLEROSIS | NF-KAPPA-B | HEXANUCLEOTIDE REPEAT | TRANSCRIPTION FACTOR | Superoxide Dismutase - genetics | Cell Proliferation | Spleen - immunology | Oligonucleotide Array Sequence Analysis | Humans | Antigens, Ly - genetics | Rats, Inbred Lew | Transcriptome | Male | MicroRNAs - metabolism | Monocytes - metabolism | Monocytes - immunology | Gene Regulatory Networks | Antigens, CD - genetics | Amyotrophic Lateral Sclerosis - drug therapy | Antigens, CD - metabolism | Microglia - immunology | RNA Interference | Spinal Cord - pathology | Inflammation Mediators - metabolism | Monocytes - pathology | Microglia - pathology | Antigens, Ly - metabolism | Female | Spleen - pathology | Amyotrophic Lateral Sclerosis - immunology | Immunomodulation | Amyotrophic Lateral Sclerosis - genetics | Mice, Inbred C57BL | Apyrase - metabolism | Rats | Mice, Transgenic | Transcription Factors - genetics | Chemotaxis | Spinal Cord - immunology | Transcription Factors - metabolism | Amyotrophic Lateral Sclerosis - pathology | Animals | Antigens, Ly - immunology | Metabolic Networks and Pathways | Antibodies, Monoclonal - administration & dosage | Apyrase - genetics | Mice | MicroRNAs - genetics | Macrophages, Alveolar - metabolism | Superoxide Dismutase-1 | Apoptosis | Care and treatment | Monocytes | MicroRNA | Amyotrophic lateral sclerosis | Development and progression | Genetic aspects | Research | Properties | Gene expression
Journal Article
STEM CELLS, ISSN 1066-5099, 06/2013, Volume 31, Issue 6, pp. 1170 - 1180
Shockwave treatment promotes bone healing of nonunion fractures. In this study, we investigated whether this effect could be due to adenosine 5′‐triphosphate... 
Shockwaves | c‐Jun | Human mesenchymal stem cells | c‐Fos | Osteogenic differentiation | ATP | p38 MAPK | C-Fos | P38 MAPK | C-Jun | EXTRACELLULAR ATP | AP-1 SUBUNITS | PROTEIN-KINASE | c-Fos | A3 RECEPTORS | CELL & TISSUE ENGINEERING | CELL BIOLOGY | c-Jun | WAVES | LYSOPHOSPHATIDIC ACID | ONCOLOGY | BONE-FORMATION | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | P38 MAPK ACTIVATION | P2X RECEPTOR | HEMATOLOGY | MARROW STROMAL CELLS | Mesenchymal Stromal Cells - enzymology | Osteogenesis - physiology | Calcium - metabolism | Humans | Alkaline Phosphatase - metabolism | Osteocalcin - genetics | Bone Marrow - physiology | Receptors, Purinergic P2X7 - genetics | Cell Differentiation - genetics | Mesenchymal Stromal Cells - cytology | Adenosine Triphosphate - metabolism | Bone Marrow - metabolism | p38 Mitogen-Activated Protein Kinases - metabolism | Cell Differentiation - physiology | Alkaline Phosphatase - genetics | Osteocalcin - metabolism | Proto-Oncogene Proteins c-jun - genetics | RNA, Messenger - genetics | Apyrase - metabolism | Cells, Cultured | Proto-Oncogene Proteins c-fos - metabolism | Mesenchymal Stromal Cells - metabolism | p38 Mitogen-Activated Protein Kinases - genetics | Signal Transduction - genetics | Proto-Oncogene Proteins c-jun - metabolism | Apyrase - genetics | Lithotripsy | Receptors, Purinergic P2X7 - metabolism | Proto-Oncogene Proteins c-fos - genetics | Signal Transduction - physiology | Medical colleges | Fractures | RNA | Adenosine triphosphate | Stem cells | Proteins | Bone marrow
Journal Article
Plant Physiology, ISSN 0032-0889, 4/2014, Volume 164, Issue 4, pp. 2054 - 2067
Journal Article
Nature Immunology, ISSN 1529-2908, 2013, Volume 14, Issue 10, pp. 1054 - 1063
Dendritic cells (DCs) control the balance between effector T cells and regulatory T cells in vivo. Hence, the study of DCs might identify mechanisms of disease... 
ENCEPHALOMYELITIS | DENDRITIC CELLS | MULTIPLE-SCLEROSIS | ARYL-HYDROCARBON RECEPTOR | INTERLEUKIN-27 | INFLAMMATION | GENE-EXPRESSION | CNS | CENTRAL-NERVOUS-SYSTEM | IMMUNOLOGY | ANTIGEN | T-Lymphocyte Subsets - immunology | Transcription, Genetic - drug effects | T-Lymphocyte Subsets - cytology | NLR Family, Pyrin Domain-Containing 3 Protein | Dendritic Cells - immunology | Encephalomyelitis, Autoimmune, Experimental - immunology | Interleukin-17 - pharmacology | Antigens, CD - genetics | Antigens, CD - metabolism | Cell Differentiation - genetics | Immune Tolerance - immunology | T-Lymphocyte Subsets - drug effects | Antibodies - immunology | Dendritic Cells - drug effects | Encephalomyelitis, Autoimmune, Experimental - genetics | Receptors, Cytokine - metabolism | Receptors, Cytokine - genetics | Dendritic Cells - metabolism | Gene Expression | Myelin Sheath - immunology | Signal Transduction | Apyrase - metabolism | Cells, Cultured | Antigen Presentation - immunology | Mice, Knockout | Gene Expression Regulation - drug effects | Cell Differentiation - immunology | Autoantibodies - immunology | Animals | Carrier Proteins - metabolism | Apyrase - genetics | Antigen Presentation - drug effects | Mice | Autoimmunity - drug effects | Cytokines - biosynthesis | Autoimmunity | Genetic aspects | Research | Interleukins | T cells | Health aspects
Journal Article
European Journal of Immunology, ISSN 0014-2980, 05/2011, Volume 41, Issue 5, pp. 1231 - 1241
CD73/ecto‐5′‐nucleotidase dephosphorylates extracellular AMP into adenosine, and it is a key enzyme in the regulation of adenosinergic signaling. The... 
Ecto‐5′‐nucleotidase/CD73 | Tumor‐infiltrating leukocytes | ATP | Type 2 macrophages | Ecto-5'-nucleotidase/CD73 | Tumor-infiltrating leukocytes | VASCULAR ADHESION PROTEIN-2 | Ecto-5 '-nucleotidase/CD73 | IFN-GAMMA | TISSUE-DAMAGE | ADENOSINE | IMMUNOLOGY | ECTO-5'-NUCLEOTIDASE CD73 | IN-VIVO | REGULATORY T-CELLS | NITRIC-OXIDE | MACROPHAGE POLARIZATION | LYMPHOCYTES | 5'-Nucleotidase - antagonists & inhibitors | 5'-Nucleotidase - genetics | T-Lymphocytes, Regulatory - metabolism | Melanoma, Experimental - metabolism | Lectins, C-Type - genetics | T-Lymphocytes, Regulatory - immunology | Melanoma, Experimental - immunology | Apyrase - pharmacology | Lymphocytes, Tumor-Infiltrating - metabolism | Interferon-gamma - genetics | Macrophages - immunology | Lymphocytes - metabolism | Purines - metabolism | Mice, Inbred C57BL | RNA, Messenger - genetics | Apyrase - metabolism | Adenosine Triphosphatases - metabolism | Melanoma, Experimental - pathology | Disease Progression | Adenosine Diphosphate - pharmacology | Mice, Knockout | Neoplasm Metastasis - genetics | Macrophages - metabolism | Animals | Mannose-Binding Lectins - genetics | Nitric Oxide Synthase Type II - genetics | Signal Transduction - drug effects | 5'-Nucleotidase - physiology | Cell Proliferation - drug effects | Mice | Adenosine Diphosphate - analogs & derivatives | Lymphocytes, Tumor-Infiltrating - immunology | Receptors, Cell Surface - genetics | Enzymes | Rodents
Journal Article
Xenotransplantation, ISSN 0908-665X, 01/2015, Volume 22, Issue 1, pp. 70 - 79
Background Xenotransplantation of porcine islets can reverse diabetes in non‐human primates. The remaining hurdles for clinical application include safe and... 
insulin | IVGTT | glucagon | xenotransplantation | genetic engineering | arginine stimulation test | C‐peptide | pig | C-peptide | MEDICINE, RESEARCH & EXPERIMENTAL | NONHUMAN PRIMATE | BETA-CELLS | N-GLYCOLYLNEURAMINIC ACID | CD46 TRANSGENIC PIG | PORCINE CTLA4-IG | HUMAN B7 | TRANSPLANTATION | XENOGRAFT SURVIVAL | CLINICAL ISLET XENOTRANSPLANTATION | HUMAN CD39 | HUMAN BLOOD | Antigens, CD - biosynthesis | Lipoproteins - genetics | Humans | Galactosyltransferases - genetics | Abatacept - genetics | Antigens, CD - genetics | Islets of Langerhans - secretion | Apyrase - biosynthesis | Sus scrofa - metabolism | Fasting - blood | Islets of Langerhans - metabolism | Swine | Fibroblasts | Insulin - genetics | Transgenes | Galactosyltransferases - deficiency | Recombinant Fusion Proteins - biosynthesis | Cell Line | Promoter Regions, Genetic | Glucose Tolerance Test | Blood Glucose - analysis | Animals, Genetically Modified | Gene Expression Regulation | Genes, Synthetic | C-Peptide - secretion | Glucose - pharmacology | Gene Knockout Techniques | Lipoproteins - biosynthesis | Animals | Apyrase - genetics | Arginine - pharmacology | Glucose - metabolism | Recombinant Fusion Proteins - genetics | Membrane Cofactor Protein - genetics | Glucagon - secretion | Abatacept - biosynthesis | Glucagon | Immunotherapy | Genes | Genetically modified organisms | Genetic research | Animal genetic engineering | Glucose | T cells | Glucose tolerance tests | Insulin | Dextrose
Journal Article