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Journal of Immunology, ISSN 0022-1767, 01/2014, Volume 192, Issue 2, pp. 623 - 629
Chronic inflammation is known to promote metabolic dysregulation in obesity and type 2 diabetes. Although the precise origin of the unchecked inflammatory... 
IMMUNE-SYSTEM | INFLAMMATION | DISEASE | RESISTANCE | FAT | AKT | IMMUNOLOGY | DIET-INDUCED OBESITY | KEY PLAYERS | ADIPOSE-TISSUE | CUTTING EDGE | Tumor Necrosis Factor-alpha - metabolism | Antigens, CD - immunology | T-Lymphocytes, Regulatory - metabolism | Epithelial Cells - metabolism | TOR Serine-Threonine Kinases - metabolism | Obesity - immunology | Insulin - immunology | Interferon-gamma - metabolism | Antigens, CD - metabolism | T-Lymphocytes, Regulatory - immunology | Epithelium - immunology | Signal Transduction - immunology | Inflammation - metabolism | Tumor Necrosis Factor-alpha - immunology | Interleukin-10 - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Receptor, Insulin - immunology | Macrophages - immunology | Hyperinsulinism - metabolism | Intra-Abdominal Fat - immunology | Transforming Growth Factor beta - immunology | Epithelium - metabolism | Mice, Inbred C57BL | Apyrase - metabolism | Cells, Cultured | Apyrase - immunology | CTLA-4 Antigen - metabolism | Inflammation - immunology | CTLA-4 Antigen - immunology | Intra-Abdominal Fat - metabolism | Obesity - metabolism | TOR Serine-Threonine Kinases - immunology | Insulin - metabolism | Macrophages - metabolism | Animals | Hyperinsulinism - immunology | Proto-Oncogene Proteins c-akt - immunology | Epithelial Cells - immunology | Interferon-gamma - immunology | Interleukin-10 - antagonists & inhibitors | Receptor, Insulin - metabolism | Mice | Interleukin-10 - immunology | Transforming Growth Factor beta - metabolism | Index Medicus | Abridged Index Medicus
Journal Article
Investigative Ophthalmology and Visual Science, ISSN 0146-0404, 10/2017, Volume 58, Issue 12, pp. 5043 - 5055
Journal Article
Nature Immunology, ISSN 1529-2908, 11/2017, Volume 18, Issue 12, pp. 1332 - 1341
Journal Article
Scientific Reports, ISSN 2045-2322, 02/2016, Volume 6, Issue 1, pp. 20254 - 20254
Tumor cell-derived exosomes (TEX) suppress functions of immune cells. Here, changes in the gene profiles of primary human T lymphocytes exposed in vitro to... 
MESSENGER-RNAS | CANCER-PATIENTS | EXTRACELLULAR VESICLES | MICROENVIRONMENT | MULTIDISCIPLINARY SCIENCES | MICROVESICLES | DIAGNOSTIC BIOMARKERS | INDUCE APOPTOSIS | OVARIAN-CANCER | MODULATION | LYMPHOCYTES | Exosomes - metabolism | Neoplasms - metabolism | CD8-Positive T-Lymphocytes - cytology | T-Lymphocytes, Regulatory - metabolism | T-Lymphocyte Subsets - cytology | Humans | Culture Media, Conditioned - pharmacology | RNA, Messenger - metabolism | Antigens, CD - metabolism | Lectins, C-Type - metabolism | T-Lymphocyte Subsets - drug effects | T-Lymphocytes, Regulatory - cytology | CD8-Positive T-Lymphocytes - metabolism | Real-Time Polymerase Chain Reaction | Microscopy, Electron, Transmission | CD4-Positive T-Lymphocytes - cytology | Apyrase - metabolism | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Antigens, Differentiation, T-Lymphocyte - metabolism | Down-Regulation - drug effects | Up-Regulation - drug effects | T-Lymphocytes, Regulatory - drug effects | T-Lymphocyte Subsets - metabolism | CD8-Positive T-Lymphocytes - drug effects | Adenosine - metabolism | Neoplasms - pathology | CD4-Positive T-Lymphocytes - drug effects | Microscopy, Fluorescence | Adenosine | Dendritic cells | CD8 antigen | Gene regulation | Data processing | T cell receptors | Lymphocytes T | Gene expression | Exosomes | Cell surface | CD4 antigen | Polymerase chain reaction | CD69 antigen | Cell activation | Lymphocytes | Down-regulation | Peripheral blood | Index Medicus
Journal Article
Neurobiology of Disease, ISSN 0969-9961, 2015, Volume 79, pp. 41 - 50
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 09/2007, Volume 152, Issue 1, pp. 141 - 150
Background and purpose: ARL 67156, 6- N, N-Diethyl-D-beta-gamma-dibromomethylene adenosine triphosphate, originally named FPL 67156, is the only commercially... 
extracellular nucleotide | CD39 | FPL 67156 | ARL 67156 | NTPDase | Ecto‐5′‐nucleotidase | ecto‐ATPase | NPP | Ecto-ATPase | Extracellular nucleotide | Ecto-5′-nucleotidase | ecto-ATPase | PHOSPHODIESTERASE-I | GUINEA-PIG | ecto-5'-nucleotidase | NUCLEOTIDE PYROPHOSPHATASES/PHOSPHODIESTERASES | CLONING | NERVE-STIMULATION | SUPERIOR CERVICAL-GANGLIA | PHARMACOLOGY & PHARMACY | ISOLATED VAS-DEFERENS | AUTOTAXIN NPP2 | DIADENOSINE POLYPHOSPHATES | 5'-Nucleotidase - antagonists & inhibitors | Nucleotidases - genetics | Uridine Triphosphate - metabolism | Humans | Substrate Specificity | Nucleotidases - antagonists & inhibitors | Antigens, CD - metabolism | Adenosine Triphosphate - pharmacology | Pyrophosphatases - antagonists & inhibitors | Adenosine Triphosphate - metabolism | Recombinant Proteins - metabolism | Recombinant Proteins - antagonists & inhibitors | Phosphoric Diester Hydrolases - metabolism | Thymidine Monophosphate - metabolism | Apyrase - antagonists & inhibitors | Adenosine Monophosphate - metabolism | Apyrase - metabolism | Enzyme Inhibitors - pharmacology | Adenosine Triphosphatases - metabolism | Dinucleoside Phosphates - metabolism | Thymidine Monophosphate - analogs & derivatives | Adenosine Triphosphate - analogs & derivatives | Hydrolysis | Pyrophosphatases - metabolism | Adenosine Triphosphatases - antagonists & inhibitors | Nucleotidases - metabolism | Animals | Adenosine Triphosphatases - genetics | Mice | Adenosine Diphosphate - metabolism | Kinetics | 5'-Nucleotidase - metabolism | Index Medicus | Research Papers
Journal Article
American Journal of Physiology - Regulatory Integrative and Comparative Physiology, ISSN 0363-6119, 04/2015, Volume 308, Issue 7, pp. R614 - R626
To what extent hypoxia alters the adenosine (ADO) system and impacts on cardiac function during embryogenesis is not known. Ectonucleoside triphosphate... 
Adenosine signaling | Hypoxia | Anoxia-reoxygenation | Arrhythmias | Glycogen metabolism | hypoxia | glycogen metabolism | PHYSIOLOGY | OXIDANT STRESS | anoxia-reoxygenation | CARDIOMYOCYTES | DEVELOPING HEART | MEDIATED EMBRYO PROTECTION | RAT HEARTS | arrhythmias | ATRIOVENTRICULAR-CONDUCTION | LUNG EPITHELIAL-CELLS | CHICK-EMBRYO | RECEPTOR ACTIVATION | adenosine signaling | MOUSE HEARTS | Adaptation, Physiological | 5'-Nucleotidase - genetics | Equilibrative Nucleoside Transport Proteins - metabolism | Adenosine Kinase - metabolism | Glycogen Synthase - metabolism | Heart - embryology | Glycogen Synthase Kinase 3 beta | RNA, Messenger - metabolism | Antigens, CD - genetics | Antigens, CD - metabolism | Hypoxia - metabolism | Glycogen - metabolism | Time Factors | Gene Expression Regulation, Developmental | Membrane Transport Proteins - genetics | Myocardium - metabolism | Membrane Transport Proteins - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Heart - physiopathology | Receptors, Purinergic P1 - genetics | Signal Transduction | Apyrase - metabolism | Hypoxia - embryology | Glycogen Synthase Kinase 3 - metabolism | Chick Embryo | Adenosine Kinase - genetics | Organogenesis | Hypoxia - genetics | Animals | Energy Metabolism | Apyrase - genetics | Adenosine - metabolism | Hypoxia - physiopathology | Receptors, Purinergic P1 - metabolism | 5'-Nucleotidase - metabolism | Equilibrative Nucleoside Transport Proteins - genetics | Complications and side effects | Adenosine | Health aspects | Heart muscle | Embryonic development | RNA | Adenosine kinase | Glycogen | Cardiovascular system | Cell growth | Poultry | Genes | Kinases | Embryos | Index Medicus | Cardiovascular and Renal Integration
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2017, Volume 12, Issue 11, pp. e0188387 - e0188387
Aim Interleukin-27 (IL-27) is involved in different inflammatory diseases; however, its role in atherosclerosis is unclear. In this study we investigated the... 
MACROPHAGES | MULTIDISCIPLINARY SCIENCES | IL-27 | TNF-ALPHA | T-CELL | SUPPRESSION | EXPRESSION | ASSOCIATION | LPS | Tumor Necrosis Factor-alpha - metabolism | Inflammasomes - metabolism | Humans | STAT Transcription Factors - metabolism | Male | Monocytes - metabolism | Interleukins - metabolism | Antigens, CD - metabolism | Lipopolysaccharides | Carotid Artery Diseases - pathology | Interleukin-1beta - metabolism | Female | Receptors, Cytokine - metabolism | Plaque, Atherosclerotic - pathology | Carotid Artery Diseases - metabolism | Interleukin-27 - blood | Receptors, Cytokine - genetics | Interleukin-27 - metabolism | Plaque, Atherosclerotic - metabolism | Signal Transduction | NLR Family, Pyrin Domain-Containing 3 Protein - metabolism | Apyrase - metabolism | Gene Expression Regulation | Up-Regulation - genetics | Interleukin-27 - genetics | Macrophages - metabolism | Minor Histocompatibility Antigens - metabolism | Carotid Artery Diseases - blood | Carotid Artery Diseases - genetics | Aged | Interleukins | Atherosclerosis | Physiological aspects | Development and progression | Inflammation | Genetic aspects | Research | Risk factors | Immunohistochemistry | Immunoassay | Interleukin | Stenosis | Cardiovascular disease | Leukocytes (mononuclear) | Activation | Macrophages | Interleukin 27 | Carotid arteries | Inflammatory diseases | Signal transduction | Cell activation | Immunology | Rodents | Interleukin 1 | Peripheral blood mononuclear cells | Measurement methods | Plaques | Medical research | Cytokines | Internal medicine | Blood vessels | Gene expression | Enzyme immunoassay | Disease control | Patients | Medicine | Monocytes | Hospitals | Arteriosclerosis | Coronary vessels | Plasma levels | In vitro methods and tests | Index Medicus
Journal Article
PLoS biology, ISSN 1544-9173, 2014, Volume 12, Issue 5, pp. e1001864 - e1001864
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2012, Volume 7, Issue 4, pp. e34730 - e34730
Background: The ectoenzymes CD39 and CD73 are expressed by a broad range of immune cells and promote the extracellular degradation of nucleotides to... 
TARGETED DISRUPTION | ACTIVATION | DENDRITIC CELLS | MACROPHAGES | MULTIDISCIPLINARY SCIENCES | REPERFUSION INJURY | ADENOSINE | INFLAMMATORY RESPONSE | RECEPTORS | ADULT | ATP-DIPHOSPHOHYDROLASE ACTIVITY | Mice, Inbred C57BL | Apyrase - metabolism | Cells, Cultured | Myocardial Infarction - metabolism | Antigens, CD - metabolism | Animals | Flow Cytometry | T-Lymphocytes - metabolism | Adenosine Triphosphate - metabolism | Erythrocytes - metabolism | Adenosine - metabolism | Myocytes, Cardiac - metabolism | Female | Mice | Granulocytes - metabolism | 5'-Nucleotidase - metabolism | Leukocytes - metabolism | B-Lymphocytes - metabolism | Enzymes | Ischemia | Analysis | Inflammation | Nucleotides | T cells | Endothelium | Heart | Oxidative stress | Flow cytometry | Heart attacks | Leukemia | Erythrocytes | Leukocytes (mononuclear) | Myocardial ischemia | Lymphocytes T | Leukocytes | CD45 antigen | Reperfusion | Red blood cells | Granulocytes | Rodents | CD73 antigen | Autocrine signalling | Cardiology | Adenosine triphosphate | CD11c antigen | Lymphoid cells | Adenosine | CD11b antigen | Myeloid cells | Neutrophils | Cardiomyocytes | Metabolism | Thrombosis | Endothelial cells | Immune systems | White blood cells | Immunosuppression | Monocytes | Lymphocytes B | Coronary vessels | Ectonucleotidase | Leukocytes (granulocytic) | Apoptosis | Index Medicus
Journal Article