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Journal Article
Journal of neuroinflammation, ISSN 1742-2094, 05/2008, Volume 5, Issue 1, pp. 22 - 22
.... An IgG1 autoantibody (NMO-IgG) that binds aquaporin 4 (AQP4) has been identified in the sera of a significant number of NMO patients, as well as in patients with two related neurologic conditions, bilateral optic neuritis... 
MYELIN OLIGODENDROCYTE GLYCOPROTEIN | NERVOUS-SYSTEM | SYSTEMIC-LUPUS-ERYTHEMATOSUS | DEVICS-SYNDROME | WATER CHANNEL PROTEIN | JAPANESE MULTIPLE-SCLEROSIS | CERVICAL LYMPH-NODES | ANTI-AQUAPORIN-4 ANTIBODY | IMMUNOLOGY | MYASTHENIA-GRAVIS | BLOOD-BRAIN-BARRIER | NEUROSCIENCES | Autoantibodies - blood | Humans | Molecular Sequence Data | Neuromyelitis Optica - genetics | Male | Neuromyelitis Optica - immunology | Autoantibodies - biosynthesis | Lymphocyte Subsets - immunology | Epitopes - immunology | Body Water - metabolism | Molecular Mimicry | Immunoglobulin G - biosynthesis | Immunoglobulin G - immunology | Spinal Cord - pathology | Aquaporin 4 - chemistry | Adult | Female | Disease Models, Animal | Amino Acid Sequence | Aquaporin 4 - immunology | Endothelial Cells - metabolism | Infection - immunology | Neuromyelitis Optica - physiopathology | Models, Molecular | Mice, Transgenic | Spinal Cord - immunology | Autoantibodies - immunology | Animals | Protein Conformation | Mice | Models, Neurological | Aquaporin 4 - physiology | Neuromyelitis Optica - etiology | Astrocytes - metabolism | Blood-Brain Barrier | Autoantibodies | Aquaporins | Physiological aspects | Development and progression | Neuromyelitis optica | Research | Health aspects | Identification and classification
Journal Article
Journal of Autoimmunity, ISSN 0896-8411, 2014, Volume 53, Issue C, pp. 67 - 77
... oligodendrocyte injury, demyelination and neuronal injury [4–8]. Complement plays a central role in NMO pathogenesis. NMO lesions show prominent vasculocentric deposition... 
Allergy and Immunology | NMO | Aquaporin-4 | Astrocyte | Demyelination | Complement-dependent cytotoxicity | OPTICA-IMMUNOGLOBULIN-G | AQUAPORIN 4 | MECHANISMS | IMMUNOLOGY | DEFICIENCY | IN-VITRO | MEMBRANE ATTACK COMPLEX | NEUROMYELITIS-OPTICA | PROTEIN CD59 | REGULATORS | TARGETED FORM | Hemoglobinuria - genetics | CD59 Antigens - immunology | Humans | Astrocytes - pathology | Immunoglobulin G - toxicity | Neuromyelitis Optica - genetics | Anemia, Hemolytic - genetics | Complement Membrane Attack Complex - immunology | Hemoglobinuria - pathology | Neuromyelitis Optica - immunology | Neuromyelitis Optica - chemically induced | Complement Membrane Attack Complex - genetics | Glial Fibrillary Acidic Protein | Astrocytes - immunology | Immunoglobulin G - immunology | Spinal Cord - pathology | Aquaporin 4 - genetics | Disease Models, Animal | Aquaporin 4 - immunology | Anemia, Hemolytic - immunology | Nerve Tissue Proteins - immunology | Anemia, Hemolytic - pathology | Cells, Cultured | CD59 Antigens - genetics | Neuromyelitis Optica - pathology | Hemoglobinuria - immunology | Nerve Tissue Proteins - genetics | Mice, Knockout | Spinal Cord - immunology | Animals | Mice | Autoimmunity | Monoclonal antibodies | Autoantibodies | Aquaporins | Analysis | Immunoglobulin G | aquaporin-4 | astrocyte | demyelination | complement-dependent cytotoxicity
Journal Article
International journal of molecular sciences, ISSN 1422-0067, 2016, Volume 17, Issue 3, pp. 273 - 273
Neuromyelitis optica (NMO) is an autoimmune, demyelinating disorder of the central nervous system (CNS) with typical clinical manifestations of optic neuritis... 
Aquaporin-4 immunoglobulin G (AQP4-IgG) | Aquaporin-1 antibody (AQP1-Ab) | Immunopathogenesis | Neuromyelitis optica spectrum disorder (NMOsd) | Neuromyelitis optica (NMO) | Neuroimmunology | Myelin oligodendrocyte glycoprotein immunoglobulin G (MOG-IgG) | neuromyelitis optica (NMO) | aquaporin-1 antibody (AQP1-Ab) | BIOCHEMISTRY & MOLECULAR BIOLOGY | aquaporin-4 immunoglobulin G (AQP4-IgG) | SPECTRUM DISORDERS | neuromyelitis optica spectrum disorder (NMOsd) | AQUAPORIN 4 | CEREBROSPINAL-FLUID | BLOOD-BRAIN-BARRIER | CHEMISTRY, MULTIDISCIPLINARY | neuroimmunology | immunopathogenesis | MULTIPLE-SCLEROSIS | ANTI-AQUAPORIN-4 ANTIBODIES | FIBRILLARY ACIDIC PROTEIN | myelin oligodendrocyte glycoprotein immunoglobulin G (MOG-IgG) | DIAGNOSTIC-CRITERIA | IMMUNOGLOBULIN-G | EXTENSIVE TRANSVERSE MYELITIS | Myelin-Oligodendrocyte Glycoprotein - immunology | Optic Nerve - pathology | Aquaporin 4 - immunology | Neuromyelitis Optica - therapy | Humans | Biomarkers - analysis | Neuromyelitis Optica - pathology | Myelin-Oligodendrocyte Glycoprotein - analysis | Neuromyelitis Optica - immunology | Spinal Cord - immunology | Autoantibodies - immunology | Animals | Aquaporin 4 - analysis | Immunoglobulin G - immunology | Spinal Cord - pathology | Optic Nerve - immunology | Autoantibodies - analysis | Immunoglobulin G - analysis | Neuromyelitis Optica - diagnosis | Nervous system | Immunoglobulins | Glycoproteins | Pathogenesis | Neurological disorders
Journal Article
Journal Article
Multiple Sclerosis Journal, ISSN 1352-4585, 2/2016, Volume 22, Issue 2, pp. 174 - 184
Objective: To investigate the clinical and magnetic resonance imaging (MRI) features of anti-myelin oligodendrocyte glycoprotein (MOG) antibody-seropositive... 
myelin | magnetic resonance imaging | Acute disseminated encephalomyelitis | demyelinating syndromes | multiple sclerosis | neuromyelitis optica | serology | pediatric multiple sclerosis | glycoprotein | myelin oligodendrocyte glycoprotein | encephalopathy | optic neuritis | SPECTRUM DISORDERS | CNS | T-CELL | NEUROSCIENCES | CLINICAL NEUROLOGY | DEMYELINATING DISEASES | DEFINITIONS | MYELIN-OLIGODENDROCYTE GLYCOPROTEIN | NEUROMYELITIS-OPTICA | AUTOIMMUNITY | PEDIATRIC MULTIPLE-SCLEROSIS | Myelin-Oligodendrocyte Glycoprotein - immunology | Humans | Male | Neuromyelitis Optica - immunology | Demyelinating Autoimmune Diseases, CNS - immunology | Demyelinating Autoimmune Diseases, CNS - physiopathology | Multiple Sclerosis - physiopathology | Flow Cytometry | Spinal Cord - pathology | Demyelinating Diseases - immunology | Female | Demyelinating Diseases - pathology | Optic Neuritis - pathology | Child | Optic Neuritis - immunology | Demyelinating Diseases - physiopathology | Aquaporin 4 - immunology | Demyelinating Autoimmune Diseases, CNS - pathology | Neuromyelitis Optica - physiopathology | Neuromyelitis Optica - pathology | Magnetic Resonance Imaging | Autoantibodies - immunology | Phenotype | Optic Neuritis - physiopathology | Encephalomyelitis, Acute Disseminated - immunology | Adolescent | Brain - pathology | Multiple Sclerosis - immunology | Multiple Sclerosis - pathology | Aquaporin 4 | Flow cytometry | Pediatrics | Immunoglobulins | Nuclear magnetic resonance--NMR | Oligodendrocyte-myelin glycoprotein | Myelin | Optic neuritis | Antibodies | Corpus callosum | Neuromyelitis | Magnetic resonance imaging | Demyelination | Encephalopathy | Green fluorescent protein | Neuritis | Children | NMO | ADEM | oligodendrocyte
Journal Article