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Science, ISSN 0036-8075, 4/2004, Volume 304, Issue 5667, pp. 108 - 110
In adult mammals, the adipocyte-derived hormone leptin acts on the brain to reduce food intake by regulating the activity of neurons in the arcuate nucleus of... 
Neurites | Neuroscience | Neurons | Food intake | Innervation | Reports | Mice | Adults | Hypothalamus | Hormones | Critical periods | ENERGY-BALANCE | BODY-WEIGHT | NERVOUS-SYSTEM | OBESITY | THYROID-HORMONE | MULTIDISCIPLINARY SCIENCES | BRAIN-DEVELOPMENT | Paraventricular Hypothalamic Nucleus - physiology | Hypothalamus - growth & development | Neurites - physiology | Culture Techniques | Dorsomedial Hypothalamic Nucleus - physiology | Hypothalamic Area, Lateral - cytology | Arcuate Nucleus of Hypothalamus - cytology | Axons - physiology | Proteins - analysis | Arcuate Nucleus of Hypothalamus - growth & development | Carbocyanines | Leptin - physiology | Paraventricular Hypothalamic Nucleus - cytology | Nerve Fibers - physiology | Hypothalamic Area, Lateral - physiology | Neurons - physiology | Leptin - pharmacology | Animals, Newborn | Eating | Signal Transduction | Dorsomedial Hypothalamic Nucleus - cytology | Hypothalamus - physiology | Hypothalamic Area, Lateral - growth & development | Intercellular Signaling Peptides and Proteins | Mice, Inbred C57BL | Feeding Behavior | Leptin - genetics | Recombinant Proteins - pharmacology | Arcuate Nucleus of Hypothalamus - physiology | Animals | Hypothalamus - cytology | Mice, Obese | Dorsomedial Hypothalamic Nucleus - growth & development | Leptin - deficiency | Paraventricular Hypothalamic Nucleus - growth & development | Agouti-Related Protein | alpha-MSH - analysis | Physiological aspects | Chemical properties | Eating (Physiology) | Leptin | Neurology | Nutrition | Rodents
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2012, Volume 7, Issue 10, p. e46923
Current evidence suggests that ghrelin, a stomach derived peptide, exerts its orexigenic action through specific modulation of Sirtuin1 (SIRT1)/p53 and... 
MAMMALIAN TARGET | ENERGY-BALANCE | HOMEOSTASIS | ACTIVATED PROTEIN-KINASE | METABOLISM | FOOD-INTAKE | MULTIDISCIPLINARY SCIENCES | RAT HYPOTHALAMUS | AMPK | AGOUTI-RELATED PEPTIDE | NEUROPEPTIDE-Y | Ghrelin - administration & dosage | TOR Serine-Threonine Kinases - metabolism | Arcuate Nucleus of Hypothalamus - cytology | Male | Neuropeptide Y - metabolism | Appetite Stimulants - administration & dosage | Time Factors | Arcuate Nucleus of Hypothalamus - drug effects | Hypothalamus - drug effects | Appetite Stimulants - pharmacology | Hypothalamus - physiology | Arcuate Nucleus of Hypothalamus - metabolism | Rats | Ghrelin - pharmacology | Arcuate Nucleus of Hypothalamus - physiology | Agouti-Related Protein - metabolism | Rats, Sprague-Dawley | Feeding Behavior - physiology | Feeding Behavior - drug effects | Transcription Factors - metabolism | Eating - drug effects | Animals | Hypothalamus - metabolism | Hypothalamus - cytology | Signal Transduction - drug effects | Neuropeptide Y | Brain | RNA | DNA binding proteins | Tumor proteins | Protein kinases | Protein binding | TOR protein | Transcription factors | Peptides | p53 Protein | Arcuate nucleus | Neuropeptides | Thyroid gland | Hypothalamus | Kinases | AMP-activated protein kinase | Experiments | Proteins | Signal transduction | Pathways | Energy | FOXO1 protein | Metabolites | Ghrelin | Rodents | Modulation | Forkhead protein | Physiology | Chronic illnesses | Stomach | AMP | Rapamycin | Metabolism | Gene expression | Fatty acids | SIRT1 protein | Medicine | Signaling | Agouti-related protein | Metabolic pathways | Diabetes | Endocrinology
Journal Article
Journal Article
Science, ISSN 0036-8075, 4/2004, Volume 304, Issue 5667, pp. 110 - 115
The fat-derived hormone leptin regulates energy balance in part by modulating the activity of neuropeptide Y and proopiomelanocortin neurons in the... 
Animal feeding behavior | Neuroscience | Neurons | Food intake | Transgenic animals | Body weight | Reports | Mice | Hypothalamus | Synapses | Endocrinology | COEXPRESSION | OBESE GENE-PRODUCT | MULTIDISCIPLINARY SCIENCES | OB/OB MICE | NEURONS | RATS | RECEPTOR | PROOPIOMELANOCORTIN MESSENGER-RNA | SYNAPTIC PLASTICITY | NEUROPEPTIDE-Y | HYPOTHALAMUS | Green Fluorescent Proteins | Peptide Hormones - pharmacology | Evoked Potentials | Recombinant Fusion Proteins - analysis | Body Weight - drug effects | Arcuate Nucleus of Hypothalamus - cytology | Neuropeptide Y - genetics | Pro-Opiomelanocortin - physiology | Leptin - physiology | Luminescent Proteins - analysis | Neuronal Plasticity - physiology | Excitatory Postsynaptic Potentials | Ghrelin | Neurons - physiology | Leptin - pharmacology | Tetrodotoxin - pharmacology | Neurons - drug effects | Pro-Opiomelanocortin - genetics | Transgenes | gamma-Aminobutyric Acid - analysis | Neuropeptide Y - physiology | Synapses - chemistry | Glutamic Acid - analysis | Eating | Mice, Transgenic | Synapses - ultrastructure | Leptin - genetics | Arcuate Nucleus of Hypothalamus - physiology | Feeding Behavior - drug effects | Patch-Clamp Techniques | Animals | Mice, Obese | In Vitro Techniques | Physiological aspects | Eating (Physiology) | Chemical properties | Leptin | Neurology | Hormones | Nutrition | Rodents
Journal Article
Journal Article
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