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PLoS ONE, 09/2013, Volume 8, Issue 9
Several neurological and behavioral dysfunctions have been reported in animals exposed to bisphenol A (BPA). However, little is known about the impact of adult... 
Aromatase
Journal Article
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 02/2012, Volume 366, Issue 6, pp. 520 - 529
Resistance to hormone therapy through activation of cellular pathways involving mTOR can develop in postmenopausal hormone-receptor–positive breast cancer.... 
TRIAL | WOMEN | MEDICINE, GENERAL & INTERNAL | EFFICACY | TAMOXIFEN | PHASE-III | LETROZOLE | SUPERIOR | AROMATASE INHIBITORS | FIRST-LINE THERAPY | ANASTROZOLE | Recurrence | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Bone Neoplasms - secondary | TOR Serine-Threonine Kinases - antagonists & inhibitors | Aromatase Inhibitors - adverse effects | Breast Neoplasms - chemistry | Aged, 80 and over | Postmenopause | Adult | Female | Aromatase Inhibitors - therapeutic use | Everolimus | Sirolimus - adverse effects | Sirolimus - analogs & derivatives | Sirolimus - therapeutic use | Kaplan-Meier Estimate | Receptor, Epidermal Growth Factor - analysis | Breast Neoplasms - drug therapy | Disease-Free Survival | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Stomatitis - chemically induced | Aged | Androstadienes - therapeutic use | Androstadienes - adverse effects | Drugs | Care and treatment | Usage | Hormone therapy | Patient outcomes | Drug utilization | Breast cancer | Product/Service Evaluations | Drug therapy, Combination | Drug therapy | TOR protein | Anastrozole | Endocrine therapy | Fatigue | Intracellular signalling | Rapamycin | Tamoxifen | Cancer therapies | Survival | Post-menopause | Fulvestrant | Signal transduction | Stomatitis | Hyperglycemia | Chemotherapy | Pneumonitis | Dyspnea | Aromatase | Antitumor activity | Respiration | Index Medicus | Abridged Index Medicus
Journal Article
Breast Cancer Research and Treatment, ISSN 0167-6806, 11/2010, Volume 124, Issue 1, pp. 89 - 99
Resistance to endocrine therapy agents has presented a clinical obstacle in the treatment of hormone-dependent breast cancer. Our laboratory has initiated a... 
TGFβ | MicroRNA | Aromatase inhibitor resistance | MiR-128a | Estrogen | TUMOR INVASION | FACTOR-BETA | TAMOXIFEN RESISTANCE | RANDOMIZED-TRIAL | AROMATASE-TRANSFECTED MCF-7 | ONCOLOGY | ESTROGEN-RECEPTOR-ALPHA | C-ELEGANS | TRANSFORMING-GROWTH-FACTOR | TGF beta | POSTMENOPAUSAL WOMEN | INHIBITOR | Receptors, Transforming Growth Factor beta - genetics | Nitriles - pharmacology | Oligonucleotide Array Sequence Analysis | Aromatase Inhibitors - pharmacology | Humans | Transforming Growth Factor beta1 - metabolism | Aromatase - metabolism | Molecular Sequence Data | MicroRNAs - metabolism | Breast Neoplasms - metabolism | Testosterone - metabolism | Aromatase - genetics | Transfection | Female | Antineoplastic Agents - pharmacology | 3' Untranslated Regions | Binding Sites | Protein-Serine-Threonine Kinases - metabolism | Estradiol - metabolism | Protein-Serine-Threonine Kinases - genetics | Gene Expression Profiling - methods | Triazoles - pharmacology | Drug Resistance, Neoplasm - genetics | Breast Neoplasms - genetics | Receptors, Transforming Growth Factor beta - metabolism | Signal Transduction - drug effects | Breast Neoplasms - pathology | Cell Line, Tumor | Cell Proliferation - drug effects | Care and treatment | DNA microarrays | Analysis | Development and progression | Breast cancer | Genetic transcription | Tamoxifen | Transforming growth factors | Protein binding | 3' Untranslated regions | Index Medicus | microRNA | miR-128a | Aromatase Inhibitor Resistance
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 06/2011, Volume 364, Issue 25, pp. 2381 - 2391
Journal Article
Human Reproduction, ISSN 0268-1161, 08/2016, Volume 31, Issue 8, pp. 1713 - 1722
Journal Article
Journal of Steroid Biochemistry and Molecular Biology, ISSN 0960-0760, 03/2017, Volume 167, pp. 23 - 32
Journal Article
Journal of Steroid Biochemistry and Molecular Biology, ISSN 0960-0760, 07/2017, Volume 171, pp. 218 - 228
The majority of breast cancer cases are estrogen receptor positive (ER ). Although, third-generation aromatase inhibitors (AIs) are used as first-line... 
Estrogen receptor-positive breast cancer | Acquired-resistance | 7α-substituted androstanes | Aromatase inhibitors | Steroids | Apoptosis | ANDROGEN RECEPTOR | DESIGN | BIOCHEMISTRY & MOLECULAR BIOLOGY | CYCLE ARREST | MODIFIED STEROIDS | ESTROGEN-RECEPTOR | TAMOXIFEN-RESISTANT | EXEMESTANE | WEAK ESTROGEN | GROWTH | ENDOCRINOLOGY & METABOLISM | 7 alpha-substituted androstanes | EXPRESSION | Androstanes - adverse effects | Receptors, Estrogen - metabolism | Androstanes - chemistry | Apoptosis - drug effects | Aromatase Inhibitors - pharmacology | Humans | Receptors, Androgen - metabolism | Aromatase Inhibitors - chemistry | Aromatase - metabolism | Drug Resistance, Neoplasm | Structure-Activity Relationship | Neoplasm Proteins - metabolism | Aromatase - chemistry | Breast Neoplasms - metabolism | Antineoplastic Agents, Hormonal - adverse effects | Aromatase - genetics | Aromatase Inhibitors - adverse effects | MCF-7 Cells | Inhibitory Concentration 50 | Female | Neoplasm Proteins - genetics | Recombinant Proteins - metabolism | Cell Line | Cell Survival - drug effects | Antineoplastic Agents, Hormonal - pharmacology | Androstanes - pharmacology | Recombinant Proteins - chemistry | Neoplasm Proteins - chemistry | Breast Neoplasms - drug therapy | Breast Neoplasms - pathology | Cell Proliferation - drug effects | Antineoplastic Agents, Hormonal - chemistry | Cell Cycle - drug effects | Index Medicus
Journal Article
Journal Article