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1. Full Text State-dependent alterations in sleep/wake architecture elicited by the M4 PAM VU0467154 – Relation to antipsychotic-like drug effects
by Gould, Robert W and Nedelcovych, Michael T and Gong, Xuewen and Tsai, Erica and Bubser, Michael and Bridges, Thomas M and Wood, Michael W and Wood, Michael R and Duggan, Mark E and Brandon, Nicholas J and Dunlop, John and Ivarsson, Magnus and Noetzel, Meredith J and Daniels, J. Scott and Niswender, Colleen M and Lindsley, Craig W and Conn, P. Jeffrey and Jones, Carrie K
Neuropharmacology, ISSN 0028-3908, 03/2016, Volume 102, pp. 244 - 253
Accumulating evidence indicates direct relationships between sleep abnormalities and the severity and prevalence of other symptom clusters in schizophrenia.... 
M4 muscarinic acetylcholine receptor | Positive allosteric modulator | Xanomeline | Electroencephalography | Clozapine | VU0467154 | muscarinic acetylcholine receptor | Allosteric Regulation - drug effects | Animals | Rats | Thiophenes - pharmacology | Male | Pyridazines - pharmacology | Receptor, Muscarinic M4 - agonists | Polysomnography | Sleep - drug effects | Arousal - drug effects | electroencephalography | clozapine | xanomeline | positive allosteric modulator
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2. Full Text Interaction between expectancies and drug effects: an experimental investigation of placebo analgesia with caffeine as an active placebo
by Bjørkedal, Espen and Flaten, Magne Arve
Psychopharmacology, ISSN 0033-3158, 6/2011, Volume 215, Issue 3, pp. 537 - 548
In a randomised placebo-controlled clinical trial it is assumed that psychosocial effects of the treatment, regression to the mean and spontaneous remission... 
Neurosciences | Biomedicine | Pain | Laser-evoked potentials | Arousal | Active placebo | Balanced placebo design | Expectancies | Pharmacology/Toxicology | Psychiatry | Placebo analgesia | Caffeine | Expectancies Laser-evoked potentials | PSYCHIATRY | PAIN PERCEPTION | INFORMATION | STIMULI | LASER-EVOKED POTENTIALS | NEUROSCIENCES | RESPONSES | HABITUATION | TEMPORAL SUMMATION | EXPECTATION | PHARMACOLOGY & PHARMACY | STRESS | Lasers - adverse effects | Analgesics - pharmacology | Central Nervous System Stimulants - pharmacology | Double-Blind Method | Placebo Effect | Humans | Evoked Potentials | Caffeine - adverse effects | Male | Arousal - drug effects | Young Adult | Pain - psychology | Central Nervous System Stimulants - adverse effects | Pain - drug therapy | Adolescent | Caffeine - pharmacology | Adult | Female | Pain Measurement | Stress, Psychological - etiology | Analgesia | Analgesics | Drug interactions | Psychopharmacology | Placebo effect | Cognitive psychology: 267 | Social science: 200 | VDP | Psykologi: 260 | Samfunnsvitenskap: 200 | Kognitiv psykologi: 267 | Psychology: 260 | Original Investigation
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3. Full Text Sex differences in guanfacine effects on drug craving and stress arousal in cocaine-dependent individuals
by Fox, Helen C and Morgan, Peter T and Sinha, Rajita
Neuropsychopharmacology, ISSN 0893-133X, 2014, Volume 39, Issue 6, pp. 1527 - 1537
Currently, no FDA-approved medication exists for the treatment of cocaine use disorder. Furthermore, as women become increasingly more at risk for the... 
stress | sex-craving | cocaine use disorder | guanfacine | drug cue | INDUCED REINSTATEMENT | PSYCHIATRY | PLACE PREFERENCE | STEROID-HORMONES | LOCUS-CERULEUS | NEUROSCIENCES | ALCOHOL-USE | CORTICOTROPIN-RELEASING-FACTOR | INDUCED RELAPSE | DOUBLE-BLIND | PHARMACOLOGY & PHARMACY | HEART-RATE | GENDER-DIFFERENCES | Humans | Male | Anxiety - drug therapy | Cocaine-Related Disorders - physiopathology | Emotions - drug effects | Arousal - drug effects | Dose-Response Relationship, Drug | Heart Rate - drug effects | Adrenergic alpha-2 Receptor Agonists - therapeutic use | Guanfacine - adverse effects | Adrenergic alpha-2 Receptor Agonists - adverse effects | Heart Rate - physiology | Adult | Female | Blood Pressure - drug effects | Blood Pressure - physiology | Cues | Emotions - physiology | Affect - drug effects | Cocaine-Related Disorders - psychology | Stress, Psychological - drug therapy | Affect - physiology | Anxiety - physiopathology | Guanfacine - therapeutic use | Treatment Outcome | Sex Characteristics | Arousal - physiology | Cocaine-Related Disorders - drug therapy | Stress, Psychological - physiopathology | development | mood | stress disorders | sex | anxiety | psychopharmacology | drug discovery | addiction & substance abuse | cocaine dependence | Original
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4. Full Text Electroencephalographic activity during sexual behavior: A novel approach to the analysis of drug effects on arousal and motivation relevant for sexual dysfunctions
by Hernández-González, Marisela and Guevara, Miguel Angel and Ågmo, Anders
Pharmacology, Biochemistry and Behavior, ISSN 0091-3057, 06/2014, Volume 121, pp. 158 - 169
The neurobiological bases of human sexual behavior are only partly understood. The etiology of most human sexual dysfunctions is not understood at all.... 
Sexual desire | Sexual arousal | Ethanol | Interhemispheric correlation | EEG | ENDOTHELIAL NO SYNTHASE | PREMATURE EJACULATION | COPULATING MALE RATS | INCENTIVE MOTIVATION | REUPTAKE INHIBITORS | PREOPTIC AREA/ANTERIOR HYPOTHALAMUS | NEUROSCIENCES | INDIVIDUAL-DIFFERENCES | HYPERSEXUAL DESIRE | MEDIAL PREFRONTAL CORTEX | DOUBLE-BLIND | BEHAVIORAL SCIENCES | PHARMACOLOGY & PHARMACY | Sexual Dysfunction, Physiological - physiopathology | Brain - anatomy & histology | Humans | Sexual Dysfunction, Physiological - drug therapy | Male | Electroencephalography | Brain - physiology | Arousal - drug effects | Sexual Behavior - psychology | Motivation - drug effects | Sexual Behavior, Animal - physiology | Penile Erection - drug effects | Female | Models, Animal | Sexual Behavior - drug effects | Sexual Behavior - physiology | Sexual Behavior, Animal - drug effects | Rats | Brain - drug effects | Arousal - physiology | Ethanol - pharmacology | Animals | Motivation - physiology | Sexual Dysfunction, Physiological - etiology | Penile Erection - physiology | Sexual disorders | Analysis | Sex
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5. Full Text Coherence and frequency in the reticular activating system (RAS)
by Garcia-Rill, Edgar and Kezunovic, Nebojsa and Hyde, James and Simon, Christen and Beck, Paige and Urbano, Francisco J
Sleep Medicine Reviews, ISSN 1087-0792, 2012, Volume 17, Issue 3, pp. 227 - 238
Summary This review considers recent evidence showing that cells in the reticular activating system (RAS) exhibit 1) electrical coupling mainly in GABAergic... 
Neurology | Sleep Medicine | Subthreshold oscillations | Calcium channels | Gamma band | Modafinil | Gap junctions | Arousal | ELECTRICAL SYNAPSES | MESOPONTINE CHOLINERGIC NUCLEI | THALAMIC NEURONS | GAMMA-OSCILLATIONS | NEURONAL OSCILLATIONS | PARADOXICAL SLEEP | NEUROSCIENCES | CLINICAL NEUROLOGY | ENTORHINAL CORTEX | CALCIUM-CHANNELS | THALAMOCORTICAL ACTIVITY | SLEEP INDUCTION ZONE | Wakefulness - drug effects | Central Nervous System Stimulants - pharmacology | Neural Pathways - drug effects | Synaptic Transmission - physiology | Reticular Formation - drug effects | Humans | Locus Coeruleus - drug effects | Sodium Channels - physiology | Intralaminar Thalamic Nuclei - physiopathology | Cerebral Cortex - physiopathology | gamma-Aminobutyric Acid - physiology | Calcium Channels - physiology | Locus Coeruleus - physiopathology | Neurons - physiology | Reticular Formation - physiopathology | Beta Rhythm - physiology | Signal Processing, Computer-Assisted | Synaptic Transmission - drug effects | Cerebral Cortex - drug effects | Neural Pathways - physiopathology | Sleep - physiology | Neurons - drug effects | Calcium Channels - drug effects | Pons - physiopathology | Pedunculopontine Tegmental Nucleus - physiopathology | Awareness - drug effects | Awareness - physiology | Sodium Channels - drug effects | Sleep - drug effects | Beta Rhythm - drug effects | Animals | Electroencephalography - drug effects | Intralaminar Thalamic Nuclei - drug effects | Wakefulness - physiology | Benzhydryl Compounds - pharmacology | Pedunculopontine Tegmental Nucleus - drug effects | GABA
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6. Full Text Elevated striatal and decreased dorsolateral prefrontal cortical activity in response to emotional stimuli in euthymic bipolar disorder: no associations with psychotropic medication load
by Hassel, Stefanie and Almeida, Jorge RC and Kerr, Natalie and Nau, Sharon and Ladouceur, Cecile D and Fissell, Kate and Kupfer, David J and Phillips, Mary L
Bipolar Disorders, ISSN 1398-5647, 12/2008, Volume 10, Issue 8, pp. 916 - 927
Hassel S, Almeida JRC, Kerr N, Nau S, Ladouceur CD, Fissell K, Kupfer DJ, Phillips ML. Elevated striatal and decreased dorsolateral prefrontal cortical... 
functional MRI | bipolar disorder | emotion processing | Emotion processing | Bipolar disorder | Functional MRI | DEPRESSION | ACTIVATION | ABNORMALITIES | PSYCHIATRY | PERFORMANCE | ANTERIOR CINGULATE | NEUROSCIENCES | CLINICAL NEUROLOGY | EXPRESSIONS | NEURAL RESPONSES | FACIAL AFFECT RECOGNITION | DYSFUNCTION | FMRI | Amygdala - physiopathology | Amygdala - drug effects | Humans | Middle Aged | Prefrontal Cortex - physiopathology | Bipolar Disorder - physiopathology | Image Interpretation, Computer-Assisted | Male | Nerve Net - drug effects | Pattern Recognition, Visual - physiology | Emotions - drug effects | Arousal - drug effects | Cerebral Cortex - physiopathology | Psychotropic Drugs - therapeutic use | Prefrontal Cortex - drug effects | Dominance, Cerebral - physiology | Limbic System - physiopathology | Adult | Female | Cerebral Cortex - drug effects | Dominance, Cerebral - drug effects | Drug Therapy, Combination | Nerve Net - physiopathology | Limbic System - drug effects | Emotions - physiology | Corpus Striatum - physiopathology | Comorbidity | Facial Expression | Bipolar Disorder - drug therapy | Oxygen - blood | Bipolar Disorder - psychology | Magnetic Resonance Imaging | Arousal - physiology | Brain Mapping | Corpus Striatum - drug effects | Pattern Recognition, Visual - drug effects | Psychotropic drugs | Medical colleges | Neurosciences | Analysis | Drug therapy
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7. Full Text General anaesthesia: from molecular targets to neuronal pathways of sleep and arousal
by Franks, Nicholas P
Nature Reviews Neuroscience, ISSN 1471-003X, 05/2008, Volume 9, Issue 5, pp. 370 - 386
The mechanisms through which general anaesthetics, an extremely diverse group of drugs, cause reversible loss of consciousness have been a long-standing... 
POSITRON-EMISSION-TOMOGRAPHY | NON-CHOLINERGIC NEURONS | MEDIAN PREOPTIC NUCLEUS | ACID TYPE-A | D-ASPARTATE RECEPTORS | WAKING DISCHARGE PATTERNS | GATED ION CHANNELS | HISTAMINERGIC TUBEROMAMMILLARY NEURONS | CEREBRAL-BLOOD-FLOW | NICOTINIC ACETYLCHOLINE-RECEPTORS | NEUROSCIENCES | Neural Pathways - drug effects | Humans | Nerve Net - drug effects | Neural Pathways - physiology | Sleep - drug effects | Thalamus - drug effects | Arousal - drug effects | Arousal - physiology | Animals | Models, Biological | Anesthetics, General - pharmacology | Thalamus - cytology | Sleep - physiology | Receptors, GABA - physiology | Receptors, GABA - drug effects | Physiological aspects | General anesthesia | Research | Consciousness | Neural networks
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