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Gastroenterology, ISSN 0016-5085, 2014, Volume 146, Issue 7, pp. 1763 - 1774
Background & Aims The NACHT, LRR, and pyrin domain–containing protein 3 (NLRP3) inflammasome induces inflammation in response to organ injury, but little is... 
Gastroenterology and Hepatology | Innate Immune Response | Immune Regulation | Pancreas | Mouse Model | ACTIVATION | NLRP3 INFLAMMASOME | GPR81 | AGONISTS | GENE | TLR9 | MICE | HEPATOTOXICITY | GASTROENTEROLOGY & HEPATOLOGY | EXPRESSION | SEVERITY | Liver - pathology | Inflammasomes - metabolism | Receptors, G-Protein-Coupled - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein | Humans | Male | NF-kappa B - metabolism | Monocytes - immunology | Lipopolysaccharides | Liver - immunology | Liver - drug effects | RNA Interference | Interleukin-1beta - metabolism | Toll-Like Receptors - drug effects | Anti-Inflammatory Agents - administration & dosage | Toll-Like Receptors - metabolism | Cytoprotection | Disease Models, Animal | Galactosamine | Chemical and Drug Induced Liver Injury - prevention & control | Anti-Inflammatory Agents - pharmacology | Down-Regulation | Liver - metabolism | Injections, Intraperitoneal | Pancreas - pathology | Pancreas - metabolism | Pancreas - immunology | Toll-Like Receptor 4 - metabolism | Chemical and Drug Induced Liver Injury - immunology | Monocytes - drug effects | Macrophages - metabolism | Signal Transduction - drug effects | Chemical and Drug Induced Liver Injury - metabolism | Sodium Lactate - pharmacology | beta-Arrestins | Mice | Receptors, G-Protein-Coupled - genetics | RNA, Small Interfering - metabolism | Monocytes - metabolism | Pancreatitis - prevention & control | Arrestins - metabolism | Dose-Response Relationship, Drug | Pancreatitis - genetics | Transfection | Inflammasomes - drug effects | Sodium Lactate - administration & dosage | Pancreatitis - immunology | Chemical and Drug Induced Liver Injury - pathology | Chemical and Drug Induced Liver Injury - etiology | Macrophages - immunology | Cell Line | Immunity, Innate - drug effects | Toll-Like Receptor 4 - drug effects | Mice, Inbred C57BL | Pancreas - drug effects | Chemical and Drug Induced Liver Injury - genetics | Pancreatitis - chemically induced | Animals | Carrier Proteins - metabolism | beta-Arrestin 2 | Inflammasomes - immunology | Macrophages - drug effects | Pancreatitis - pathology | Pancreatitis - metabolism | Ceruletide | Lactates | Gastrointestinal diseases | Inflammation | Index Medicus | Abridged Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 05/2015, Volume 290, Issue 22, pp. 13875 - 13887
Journal Article
Developmental Cell, ISSN 1534-5807, 11/2015, Volume 35, Issue 4, pp. 497 - 512
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2012, Volume 109, Issue 11, pp. 4146 - 4151
Journal Article
Nature Communications, ISSN 2041-1723, 10/2015, Volume 6, Issue 1, pp. 8472 - 8472
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2014, Volume 134, Issue 2, pp. 420 - 428.e15
Background Five different G protein–coupled sphingosine-1-phosphate (S1P) receptors (S1P1-S1P5) regulate a variety of physiologic and pathophysiologic... 
Allergy and Immunology | primary immunodeficiencies | autoimmunity | fingolimod | FTY720 | Sphingosine-1-phosphate | circulation | migration | B cells | ACTIVATION | LYMPHOID ORGANS | WISKOTT-ALDRICH-SYNDROME | BONE-MARROW | SYNDROME PROTEIN | T-CELL | IMMUNOLOGY | DEFICIENCY | WASP | S1P | ALLERGY | DOCK8 MUTATIONS | Common Variable Immunodeficiency - immunology | Wiskott-Aldrich Syndrome Protein - genetics | Protein-Tyrosine Kinases - metabolism | Humans | Arrestins - immunology | Leukemia, Lymphocytic, Chronic, B-Cell - genetics | Antigens, CD - genetics | Time-Lapse Imaging | Antigens, CD - metabolism | Lectins, C-Type - metabolism | Guanine Nucleotide Exchange Factors - metabolism | Adaptor Proteins, Signal Transducing - immunology | Receptors, Lysosphingolipid - metabolism | Leukemia, Lymphocytic, Chronic, B-Cell - immunology | Guanine Nucleotide Exchange Factors - genetics | B-Lymphocyte Subsets - pathology | Signal Transduction | Common Variable Immunodeficiency - pathology | Antigens, Differentiation, T-Lymphocyte - metabolism | Common Variable Immunodeficiency - genetics | Leukemia, Lymphocytic, Chronic, B-Cell - pathology | B-Lymphocyte Subsets - metabolism | Wiskott-Aldrich Syndrome Protein - immunology | beta-Arrestins | Leukemia, Lymphocytic, Chronic, B-Cell - metabolism | Cell Movement | Antigens, CD - immunology | Lectins, C-Type - immunology | Arrestins - genetics | Lectins, C-Type - genetics | Arrestins - metabolism | Protein-Tyrosine Kinases - immunology | Protein-Tyrosine Kinases - genetics | Protein Isoforms - metabolism | Receptors, Lysosphingolipid - genetics | Wiskott-Aldrich Syndrome Protein - metabolism | B-Lymphocyte Subsets - immunology | Multiple Sclerosis - metabolism | Cell Line | Antigens, Differentiation, T-Lymphocyte - immunology | Gene Expression Regulation | Multiple Sclerosis - genetics | Receptors, Lysosphingolipid - immunology | Common Variable Immunodeficiency - metabolism | beta-Arrestin 2 | Adaptor Proteins, Signal Transducing - genetics | Antigens, Differentiation, T-Lymphocyte - genetics | Guanine Nucleotide Exchange Factors - immunology | Multiple Sclerosis - immunology | Multiple Sclerosis - pathology | Primary Cell Culture | Adaptor Proteins, Signal Transducing - metabolism | Protein Isoforms - immunology | Protein Isoforms - genetics | Phosphates | Multiple sclerosis | Sphingosine | Immunodeficiency | Medical genetics | Sphingolipids | G proteins | Health aspects | Lymphocyte receptors | Immunoglobulins | Mutation | Lymphocytes | Immune system | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 05/2009, Volume 119, Issue 5, pp. 1312 - 1321
Journal Article
Journal Article