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Annals of the Rheumatic Diseases, ISSN 0003-4967, 04/2012, Volume 71, Issue 4, pp. 575 - 581
...), a key inhibitor of autophagy, has disease-modifying activity in experimental osteoarthritis... 
Life Sciences & Biomedicine | Rheumatology | Science & Technology | Arthritis, Experimental - drug therapy | TOR Serine-Threonine Kinases - metabolism | Immunosuppressive Agents - therapeutic use | Male | Osteoarthritis - drug therapy | Autophagy - drug effects | Arthritis, Experimental - metabolism | Arthritis, Experimental - pathology | Anti-Inflammatory Agents - therapeutic use | Osteoarthritis - pathology | Immunosuppressive Agents - pharmacology | Chondrocytes - metabolism | ADAMTS5 Protein | Drug Evaluation, Preclinical - methods | Sirolimus - therapeutic use | Anti-Inflammatory Agents - pharmacology | Mice, Inbred C57BL | Osteoarthritis - metabolism | Treatment Outcome | Sirolimus - pharmacology | Cartilage, Articular - pathology | ADAM Proteins - metabolism | Animals | Signal Transduction - drug effects | Mice | Autophagy (Cytology) | Care and treatment | Rapamycin | Dosage and administration | Models | Research | Osteoarthritis | Protein kinases | Knee | Antigens | Enzymes | Aging | Homeostasis | Calcification | Arthritis | Inflammation | Kinases | Gene expression | Autophagy | Apoptosis | Immunohistochemistry | TOR protein | Synovitis | Phosphorylation | Cartilage (articular) | Joint diseases | Synovium | Signal transduction | Cell death | ribosomal protein S6 | Interleukin 1 | Immunofluorescence | Ligaments | Phagocytosis | Cartilage diseases | Index Medicus | mTOR | autophagy | osteoarthritis | cartilage | rapamycin
Journal Article
Seminars in immunopathology, ISSN 1863-2300, 10/2011, Volume 34, Issue 1, pp. 43 - 62
The interaction of coagulation factors with the perivascular environment affects the development of disease in ways that extend beyond their traditional roles... 
Autoimmunity | Complement receptor 3 | Multiple sclerosis | Stroke | Alzheimer’s disease | Internal Medicine | Macrophages | Blood brain barrier | Inflammatory disease | Microglia | Biomedicine | Immunology | Rheumatoid arthritis | CD11b/CD18 | Atherosclerosis | Plasminogen | Anticoagulant therapy | Alzheimer's disease | Pathology | Life Sciences & Biomedicine | Science & Technology | Colitis - genetics | Humans | Brain Injuries - metabolism | Arthritis, Rheumatoid - metabolism | Bacterial Infections - genetics | Inflammation - metabolism | Blood Coagulation - immunology | Muscular Dystrophy, Duchenne - immunology | Alzheimer Disease - immunology | Fibrinogen - immunology | Thromboplastin - immunology | Pulmonary Fibrosis - immunology | Vascular Diseases - genetics | Brain Injuries - genetics | Thrombin - genetics | Kidney Diseases - immunology | Arthritis, Rheumatoid - genetics | Neoplasms - immunology | Colitis - metabolism | Muscular Dystrophy, Duchenne - genetics | Bacterial Infections - metabolism | Neoplasms - metabolism | Pulmonary Fibrosis - genetics | Spinal Cord Injuries - genetics | Kidney Diseases - genetics | Stroke - genetics | Brain Injuries - immunology | Neoplasms - genetics | Bacterial Infections - immunology | Pulmonary Fibrosis - metabolism | Colitis - immunology | Thrombin - immunology | Stroke - immunology | Kidney Diseases - metabolism | Multiple Sclerosis - metabolism | Vascular Diseases - immunology | Spinal Cord Injuries - metabolism | Multiple Sclerosis - genetics | Inflammation - immunology | Fibrinogen - genetics | Stroke - metabolism | Animals | Thromboplastin - genetics | Alzheimer Disease - metabolism | Fibrinogen - metabolism | Inflammation - genetics | Multiple Sclerosis - immunology | Blood Coagulation - genetics | Spinal Cord Injuries - immunology | Muscular Dystrophy, Duchenne - metabolism | Thrombin - metabolism | Thromboplastin - metabolism | Alzheimer Disease - genetics | Arthritis, Rheumatoid - immunology | Vascular Diseases - metabolism | Nervous system diseases | Bacterial infections | Oncology, Experimental | Thrombin | Inflammation | Anticoagulants (Medicine) | Research | Rheumatoid factor | Fibrin | Fibrinogen | Genetic research | Colitis | Cancer | Index Medicus | Traumatic brain injury | Coagulation | Tissue factor | hemostasis | Spinal cord injury | Inflammatory diseases | Kidney | Signal transduction | Duchenne's muscular dystrophy | Neurodegenerative diseases | Therapeutic applications | Thrombosis | Coagulation factors | Infection | Molecular modelling | Fibrosis | Brain injury
Journal Article
Clinical and experimental medicine, ISSN 1591-9528, 04/2014, Volume 15, Issue 1, pp. 121 - 126
Journal Article
Annals of the rheumatic diseases, ISSN 0003-4967, 04/2017, Volume 76, Issue 4, pp. 748 - 755
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 06/2011, Volume 108, Issue 27, pp. 11193 - 11198
MicroRNA (miRNA) species (miR) regulate mRNA translation and are implicated as mediators of disease pathology via coordinated regulation of molecular effector... 
Myeloid cells | MicroRNA | Messenger RNA | Cytokines | Synovial membrane | Rheumatoid arthritis | Collagens | Arthritis | Inflammation | Macrophages | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Arthritis, Experimental - genetics | Humans | Inositol Polyphosphate 5-Phosphatases | Synovial Membrane - immunology | Synovial Membrane - pathology | MicroRNAs - metabolism | Case-Control Studies | Arthritis, Experimental - metabolism | Arthritis, Experimental - pathology | Arthritis, Rheumatoid - metabolism | Base Sequence | Inflammation Mediators - metabolism | Phosphoric Monoester Hydrolases - genetics | Osteoarthritis - immunology | Osteoarthritis - metabolism | Arthritis, Experimental - immunology | Synovial Membrane - metabolism | Osteoarthritis - genetics | Arthritis, Rheumatoid - pathology | Mice, Knockout | Arthritis, Rheumatoid - genetics | Animals | Mice | MicroRNAs - genetics | Arthritis, Rheumatoid - immunology | Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases | Phosphoric Monoester Hydrolases - metabolism | Cytokines - biosynthesis | Physiological aspects | Genetic aspects | Health aspects | Proteins | Ribonucleic acid--RNA | Gene expression | Cells | Inositol | Translation | Autoantibodies | Therapeutic applications | Helper cells | Data processing | Homology | Src protein | Synovial fluid | Collagen | miRNA | Osteoarthritis | Tumor necrosis factor- alpha | Index Medicus | Biological Sciences
Journal Article
Lasers in medical science, ISSN 1435-604X, 04/2011, Volume 27, Issue 1, pp. 71 - 78
Journal Article
Journal of bone and mineral metabolism, ISSN 0914-8779, 11/2018, Volume 36, Issue 6, pp. 628 - 639
Journal Article