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Nature medicine, ISSN 1546-170X, 2012, Volume 18, Issue 7, pp. 1069 - 1076
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 12/2015, Volume 74, Issue 12, pp. 2254 - 2258
Journal Article
Journal of the neurological sciences, ISSN 0022-510X, 2013, Volume 333, Issue 1-2, pp. 76 - 87
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2011, Volume 108, Issue 27, pp. 11193 - 11198
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 2012, Volume 109, Issue 50, pp. 20602 - 20607
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 04/2012, Volume 71, Issue 4, pp. 575 - 581
Journal Article
Bone (New York, N.Y.), ISSN 8756-3282, 2016, Volume 83, pp. 210 - 219
Journal Article
Journal of translational medicine, ISSN 1479-5876, 2018, Volume 16, Issue 1, pp. 56 - 16
Background: MIV-711 is a highly potent and selective cathepsin K inhibitor. The current article summarizes the therapeutic effects of MIV-711 on joint pathology in rabbits subjected to anterior cruciate ligament transection (ACLT... 
Cartilage | Cathepsin K | CTX-I | Subchondral bone | CTX-II | HP-1 | Osteoarthritis | MEDICINE, RESEARCH & EXPERIMENTAL | CONTROLLED-TRIAL | SUBCHONDRAL BONE ATTRITION | TURNOVER | ANTERIOR CRUCIATE LIGAMENT | CANINE MODELS | DEGENERATION | TRANSECTION MODEL | II COLLAGEN | ARTICULAR-CARTILAGE | KNEE OSTEOARTHRITIS | Anterior Cruciate Ligament | Biomarkers - urine | Organic Chemicals | Male | Cysteine Proteinase Inhibitors - pharmacokinetics | Cysteine Proteinase Inhibitors - blood | Osteoarthritis - drug therapy | Female | Osteoarthritis - pathology | Principal Component Analysis | Cathepsin K - antagonists & inhibitors | Disease Models, Animal | Anterior Cruciate Ligament Injuries - drug therapy | Cartilage, Articular - diagnostic imaging | Cysteine Proteinase Inhibitors - therapeutic use | Rabbits | Joints - drug effects | Osteoarthritis - diagnostic imaging | Joints - diagnostic imaging | Joints - pathology | Osteoarthritis - blood | Biomarkers - blood | Cartilage, Articular - pathology | Animals | Cysteine Proteinase Inhibitors - pharmacology | Bone Resorption - pathology | Dogs | Cartilage, Articular - drug effects | Treatment outcome | Care and treatment | Usage | Cathepsins | Radioisotope scanning | Research | Gene expression | Analysis | Genetic aspects | Diagnosis | Joints | Health aspects
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2010, Volume 107, Issue 5, pp. 2159 - 2164
The beneficial effects of probiotics have been described in many diseases, but the mechanism by which they modulate the immune system is poorly understood. In... 
T lymphocytes | Probiotics | Inflammatory bowel diseases | Immune disorders | Population growth | Cytokines | Dendritic cells | B lymphocytes | Drug regulation | Mice | Inflammatory bowel disease | Inflammation | Atopic dermatitis | Rheumatoid arthritis | Regulatory T cell | MIGRATION | BACTERIA | MULTIDISCIPLINARY SCIENCES | RETINOIC-ACID | atopic dermatitis | regulatory T cell | INDUCTION | rheumatoid arthritis | FOXP3 | inflammatory bowel disease | EXPERIMENTAL ARTHRITIS | INFLAMMATORY-BOWEL-DISEASE | inflammation | ORAL TOLERANCE | MICE | EXPRESSION | Probiotics - administration & dosage | T-Lymphocytes, Regulatory - metabolism | Arthritis, Experimental - therapy | Dendritic Cells - immunology | Inflammatory Bowel Diseases - immunology | Dendritic Cells - pathology | Adoptive Transfer | Dermatitis, Atopic - therapy | T-Lymphocytes, Regulatory - pathology | T-Lymphocytes, Regulatory - immunology | Arthritis, Experimental - pathology | CD11c Antigen - metabolism | Forkhead Transcription Factors - metabolism | Inflammatory Bowel Diseases - pathology | Dermatitis, Atopic - immunology | Immune System Diseases - pathology | Disease Models, Animal | Immune System Diseases - immunology | Mice, Transgenic | Arthritis, Experimental - immunology | Dermatitis, Atopic - pathology | Immunosuppression | Animals | Immune System Diseases - therapy | Mice, Inbred BALB C | Inflammatory Bowel Diseases - therapy | Biological Sciences
Journal Article
PloS one, ISSN 1932-6203, 2017, Volume 12, Issue 9, p. e0184624
Journal Article