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Journal of Immunology, ISSN 0022-1767, 07/2012, Volume 189, Issue 1, pp. 365 - 372
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 09/2015, Volume 287, Issue 3, pp. 299 - 305
Tumor necrosis factor-α (TNF-α) is a pro-inflammatory cytokine produced by monocytes/macrophage that plays a pathological role in rheumatoid arthritis (RA). In... 
Synovial fibroblasts | MAP kinase | TNF-α | Rheumatoid arthritis | ASK1 | Thymoquinone | PATHWAYS | OXIDATIVE STRESS | ACTIVATION | TNF-alpha | P38 MAPK | MECHANISMS | ROLES | VCAM-1 EXPRESSION | PHARMACOLOGY & PHARMACY | TOXICOLOGY | EPIGALLOCATECHIN-3-GALLATE | CADHERIN-11 | Arthritis, Rheumatoid - surgery | Fibroblasts - enzymology | Phosphorylation | Synovial Membrane - enzymology | Humans | Synovial Membrane - immunology | Synovial Membrane - drug effects | Cell Adhesion Molecules - immunology | Extracellular Signal-Regulated MAP Kinases - metabolism | Dose-Response Relationship, Drug | Inflammation Mediators - metabolism | p38 Mitogen-Activated Protein Kinases - metabolism | Interleukin-8 - metabolism | MAP Kinase Kinase Kinase 5 - metabolism | Interleukin-6 - metabolism | Inflammation Mediators - immunology | Anti-Inflammatory Agents - pharmacology | Cells, Cultured | Arthritis, Rheumatoid - enzymology | Cell Adhesion - drug effects | Cell Adhesion Molecules - metabolism | Benzoquinones - pharmacology | Tumor Necrosis Factor-alpha - pharmacology | Signal Transduction - drug effects | Fibroblasts - drug effects | Interleukin-6 - immunology | Fibroblasts - immunology | Enzyme Activation | Arthritis, Rheumatoid - immunology | Interleukin-8 - immunology | MAP Kinase Kinase Kinase 5 - immunology | Index Medicus | APOPTOSIS | PHOSPHORYLATION | MACROPHAGES | RANUNCULACEAE | VIABILITY | MONOCYTES | EVALUATION | ANIMAL TISSUES | 60 APPLIED LIFE SCIENCES | FIBROBLASTS | ADHESION | RHEUMATIC DISEASES | INHIBITION | MAPS | DOSES | INFLAMMATION | SYNTHESIS | RADIOPROTECTIVE SUBSTANCES | RESIDUES | synovial fibroblasts
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 02/2016, Volume 75, Issue 2, pp. 422 - 429
ObjectiveTo investigate the effects of BET bromodomain protein inhibition on inflammatory activation and functional properties of rheumatoid arthritis synovial... 
TRIAL | KNEE | EPIGENETICS | ACTIVATION | SECUKINUMAB | CHROMATIN | TISSUE | DOUBLE-BLIND | ANTI-INTERLEUKIN-17A MONOCLONAL-ANTIBODY | RHEUMATOLOGY | BET PROTEIN | Immunohistochemistry | Tumor Necrosis Factor-alpha - metabolism | Gene Expression - drug effects | Humans | Lipopolysaccharides - metabolism | Arthritis, Rheumatoid - enzymology | Matrix Metalloproteinase 3 - metabolism | Nuclear Proteins - metabolism | RNA, Messenger - metabolism | Synovial Membrane - metabolism | Heterocyclic Compounds, 4 or More Rings - pharmacology | Osteoarthritis - genetics | Osteoarthritis - enzymology | Transcription Factors - metabolism | Arthritis, Rheumatoid - genetics | Interleukin-1beta - metabolism | Interleukin-8 - metabolism | Toll-Like Receptors - metabolism | Matrix Metalloproteinase 1 - metabolism | Interleukin-6 - metabolism | Protein-Serine-Threonine Kinases - metabolism | RNA-Binding Proteins - metabolism | Fibroblasts - metabolism | Epigenetic inheritance | Care and treatment | Interleukins | Tumor necrosis factor | Rheumatoid arthritis | Dosage and administration | Research | Enzymes | Immunoglobulins | Statistical analysis | Disease | Cytokines | Laboratories | Gene expression | Variance analysis | Bone surgery | Studies | Proteins | Pathology | Rodents | DNA methylation | Epigenetics | Fibroblasts | Tumor necrosis factor-TNF | Chemokines | Deoxyribonucleic acid--DNA | Index Medicus
Journal Article
American Journal of Pathology, The, ISSN 0002-9440, 2012, Volume 180, Issue 5, pp. 1906 - 1916
Journal Article
Rheumatology (Oxford, England), ISSN 1462-0324, 12/2014, Volume 53, Issue 12, pp. 2270 - 2279
Journal Article
Journal of Immunology, ISSN 0022-1767, 03/2014, Volume 192, Issue 5, pp. 2082 - 2090
Journal Article
Nature Genetics, ISSN 1061-4036, 08/2003, Volume 34, Issue 4, pp. 395 - 402
Journal Article
Journal of Cellular and Molecular Medicine, ISSN 1582-1838, 04/2017, Volume 21, Issue 4, pp. 781 - 790
To probe the role of protein arginine methyltransferase 5 ( PRMT 5) in regulating inflammation, cell proliferation, migration and invasion of fibroblast‐like... 
migration | protein arginine methyltransferases 5 | inflammation | rheumatoid arthritis | fibroblast‐like synoviocytes | fibroblast-like synoviocytes | MEDICINE, RESEARCH & EXPERIMENTAL | PRMT5 | METHYLATION | TISSUE | CELL BIOLOGY | GROWTH | SUPPRESSES | MUTATIONS | EXPRESSION | KINASES | Inflammation - pathology | Fibroblasts - enzymology | Humans | Protein-Arginine N-Methyltransferases - antagonists & inhibitors | NF-kappa B - metabolism | Synoviocytes - enzymology | Synoviocytes - drug effects | Osteoarthritis - enzymology | Inflammation - complications | I-kappa B Kinase - metabolism | Inflammation Mediators - metabolism | Osteoarthritis - pathology | Proto-Oncogene Proteins c-akt - metabolism | Arthritis, Rheumatoid - enzymology | Up-Regulation - genetics | Enzyme Activation - drug effects | Fibroblasts - pathology | Arthritis, Rheumatoid - pathology | Protein-Arginine N-Methyltransferases - metabolism | Up-Regulation - drug effects | Cell Movement - drug effects | Tumor Necrosis Factor-alpha - pharmacology | Fibroblasts - drug effects | Synoviocytes - pathology | Cell Proliferation - drug effects | Inflammation - enzymology | Rheumatoid factor | Methyltransferases | Arginine | Inflammation | Gene expression | Osteoarthritis | Enzyme-linked immunosorbent assay | Proteins | Fibroblasts | Cell growth | Kinases | Rheumatoid arthritis | Index Medicus | Original
Journal Article