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The Journal of Immunology, ISSN 0022-1767, 12/2008, Volume 181, Issue 11, pp. 8010 - 8017
Sphingosine kinase (SphK) is a key enzyme in the sphingolipid metabolic pathway responsible for phosphorylating sphingosine into sphingosine-1-phosphate (S1P).... 
RHEUMATOID-ARTHRITIS | SIGNAL-TRANSDUCTION | SYNOVIAL-CELLS | TUMOR-NECROSIS-FACTOR | CYTOKINE PRODUCTION | HUMAN NEUTROPHILS | FUNCTIONAL-CHARACTERIZATION | MOLECULAR-CLONING | CALCIUM MOBILIZATION | IMMUNOLOGY | LYMPHOCYTE EGRESS | Inflammation - pathology | Lysophospholipids - metabolism | Phosphotransferases (Alcohol Group Acceptor) - immunology | Humans | Matrix Metalloproteinase 9 - immunology | Lysophospholipids - immunology | Cyclooxygenase 2 - biosynthesis | Signal Transduction - immunology | RNA, Small Interfering - immunology | U937 Cells | Leukocytes, Mononuclear - immunology | Mice, Inbred DBA | Sphingosine - metabolism | Collagen Type II - pharmacology | Cytokines - blood | Cytokines - immunology | Disease Models, Animal | Inflammation Mediators - immunology | Matrix Metalloproteinase 9 - biosynthesis | Collagen Type II - immunology | Gene Expression Regulation - immunology | Jurkat Cells | Enzyme Inhibitors - pharmacology | Inflammation Mediators - blood | Arthritis, Rheumatoid - enzymology | Sphingosine - immunology | Inflammation - immunology | Synovial Fluid - enzymology | Neovascularization, Physiologic - immunology | Arthritis, Rheumatoid - pathology | Phosphotransferases (Alcohol Group Acceptor) - metabolism | Sphingosine - pharmacology | Synovial Fluid - immunology | Leukocytes, Mononuclear - pathology | Phosphotransferases (Alcohol Group Acceptor) - antagonists & inhibitors | Receptors, Lysosphingolipid - immunology | Sphingosine - analogs & derivatives | Animals | Signal Transduction - drug effects | Cyclooxygenase 2 - metabolism | Leukocytes, Mononuclear - enzymology | Cell Proliferation - drug effects | Mice | Arthritis, Rheumatoid - immunology | Inflammation - enzymology | Receptors, Lysosphingolipid - biosynthesis
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 06/2009, Volume 206, Issue 6, pp. 1435 - 1449
Journal Article
BMC Musculoskeletal Disorders, ISSN 1471-2474, 03/2014, Volume 15, Issue 1, pp. 93 - 93
Background: Matrix metalloproteinase-3 (MMP-3) plays an important role in the pathology of rheumatoid arthritis (RA) and ankylosing spondylitis (AS).... 
Serum | Rheumatoid arthritis | Ankylosing spondylitis | MMP-3 | Active form | RHEUMATOID-ARTHRITIS | ACTIVATION | ANKYLOSING-SPONDYLITIS | RHEUMATOLOGY | FIBROBLASTS | 4-AMINOPHENYLMERCURIC ACETATE | RADIOGRAPHIC PROGRESSION | SERUM-LEVELS | IN-VIVO | TISSUE INHIBITOR | MATRIX METALLOPROTEINASE-3 STROMELYSIN | ORTHOPEDICS | Arthritis, Rheumatoid - blood | Synovial Membrane - enzymology | Humans | Spondylitis, Ankylosing - blood | Spondylitis, Ankylosing - enzymology | Molecular Sequence Data | Male | Cartilage - drug effects | Synovial Membrane - drug effects | Oncostatin M - pharmacology | Matrix Metalloproteinase 3 - immunology | Arthritis, Rheumatoid - drug therapy | Sensitivity and Specificity | Female | C-Reactive Protein - analysis | Cartilage - secretion | Antibodies, Monoclonal - immunology | Organ Culture Techniques | Antirheumatic Agents - therapeutic use | Severity of Illness Index | Amino Acid Sequence | Reproducibility of Results | Specific Pathogen-Free Organisms | Enzyme-Linked Immunosorbent Assay | Spondylitis, Ankylosing - drug therapy | Arthritis, Rheumatoid - enzymology | Treatment Outcome | Inflammation | Tumor Necrosis Factor-alpha - pharmacology | Synovial Membrane - secretion | Animals | Osteoarthritis, Knee - pathology | Biomarkers | Mice | Enzyme Activation | Cartilage - enzymology | Matrix Metalloproteinase 3 - blood | Matrix Metalloproteinase 3 - secretion | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Medical research | Medical examination | C-reactive protein | Medical law | Medicine, Experimental | Development and progression | Amino acids | Blood | Proteins | Studies | Data analysis | Hospitals | Disease | Peptides | Rheumatic diseases | Laboratory animals | Binding sites
Journal Article
Journal Article
Nature, ISSN 0028-0836, 07/2010, Volume 466, Issue 7303, pp. 243 - 247
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 09/2011, Volume 121, Issue 9, pp. 3517 - 3527
Journal Article
Clinical and Experimental Rheumatology, ISSN 0392-856X, 2016, Volume 34, Issue 1, pp. 106 - 110
Journal Article
Arthritis Research and Therapy, ISSN 1478-6354, 06/2009, Volume 11, Issue 3, pp. R83 - R83
Journal Article
Cellular Immunology, ISSN 0008-8749, 07/2013, Volume 284, Issue 1-2, pp. 51 - 59
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 08/2015, Volume 172, Issue 15, pp. 3805 - 3816
Journal Article