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Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 1761, Volume 289, Issue 18, pp. 12457 - 12466
Background: Most commercial TNF inhibitors are biomacromolecules. Results: A lead compound named C87 was identified using computer-aided drug design and could... 
RHEUMATOID-ARTHRITIS | Computer Modeling | BIOCHEMISTRY & MOLECULAR BIOLOGY | RECEPTOR SUPERFAMILY | Inflammation | CELL-DEATH | JNK ACTIVATION | PEPTIDOMIMETICS | Surface Plasmon Resonance (SPR) | AUTOIMMUNE-DISEASES | Cell Death | Tumor Necrosis Factor (TNF) | THERAPEUTIC TARGET | Cell Signaling | Small Molecules | TNF-ALPHA | BINDING | GALACTOSAMINE | Surface Plasmon Resonance | Tumor Necrosis Factor-alpha - metabolism | Small Molecule Libraries - pharmacology | Hepatitis, Animal - prevention & control | Humans | Hepatitis, Animal - genetics | Structure-Activity Relationship | Receptors, Tumor Necrosis Factor, Type I - metabolism | Dose-Response Relationship, Drug | Hepatitis, Animal - metabolism | Inflammation - metabolism | Caspases - metabolism | MAP Kinase Kinase 4 - metabolism | Protein Binding - drug effects | Molecular Structure | Disease Models, Animal | Cell Survival - drug effects | Jurkat Cells | Blotting, Western | Hydrazones - chemistry | Hydrazones - pharmacology | Small Molecule Libraries - chemistry | Tumor Necrosis Factor-alpha - pharmacology | Animals | Signal Transduction - drug effects | K562 Cells | Cell Line, Tumor | HL-60 Cells | Inflammation - genetics | Thiazoles - chemistry | Inflammation - prevention & control | Mice | Mice, Inbred BALB C | Thiazoles - pharmacology | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Index Medicus | Immunology
Journal Article
Massachusetts Medical Journal, 06/1886, Volume 6, Issue 6, p. 272
Journal Article
The Retrospect of Practical Medicine and Surgery, 07/1886, Volume XCIII, p. 20
Journal Article
Journal Article
Musculoskeletal Care, ISSN 1478-2189, 09/2014, Volume 12, Issue 3, pp. 182 - 189
Journal Article
Clinical & Experimental Immunology, ISSN 0009-9104, 07/2011, Volume 165, Issue 1, pp. 121 - 129
Oestradiol and the selective oestrogen receptor modulator (SERM) raloxifene have been shown to ameliorate collagen‐induced arthritis (CIA) in rats and in mice.... 
BMD | oestradiol | CAIA | CIA | raloxifene | luciferase‐ERE | ovariectomy | Ovariectomy | Oestradiol | Raloxifene | Luciferase-ERE | luciferase-ERE | RHEUMATOID-ARTHRITIS | COLLAGEN-INDUCED ARTHRITIS | BONE-MINERAL DENSITY | ANTIBODY-INDUCED ARTHRITIS | MONOCLONAL-ANTIBODY | ARTHRITOGENIC ANTIBODIES | IMMUNOLOGY | ESTROGEN-RECEPTOR-BETA | INDUCED SUPPRESSION | II COLLAGEN | REPLACEMENT THERAPY | Arthritis, Experimental - drug therapy | Humans | Osteoporosis, Postmenopausal - complications | Arthritis, Experimental - chemically induced | Female | Mice, Inbred DBA | Response Elements - genetics | Osteoporosis, Postmenopausal - etiology | Immunomodulation | Collagen - immunology | Transgenes - genetics | Estradiol - administration & dosage | Mice, Transgenic | Selective Estrogen Receptor Modulators - administration & dosage | Arthritis, Experimental - complications | Arthritis, Experimental - immunology | Biomarkers - blood | Disease Progression | Osteoporosis, Postmenopausal - drug therapy | Antibodies - administration & dosage | Collagen - administration & dosage | Animals | Osteoporosis, Postmenopausal - immunology | Raloxifene Hydrochloride - administration & dosage | Bone Marrow - pathology | Mice | Osteoporosis | Analysis | Collagen | Luciferase | Development and progression | Arthritis | Inflammation | Postmenopausal women | Estradiol | Medical research | Index Medicus | Indexing in process | Animal Studies | Rheumatology and Autoimmunity | bone mineral density | Endokrinologi och diabetes | Reumatologi och inflammation | raloxifene rheumatoid arthritis | Estrogen | Immunologi inom det medicinska området | collagen antibody induced arthritis | Immunology in the medical area | Endocrinology and Diabetes
Journal Article
Journal Article