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Toxicology and Applied Pharmacology, ISSN 0041-008X, 07/2013, Volume 270, Issue 2, pp. 174 - 184
CYP3A proteins are the most abundant CYPs in the liver and intestines, and they play a pivotal role in drug metabolism. In mammals, genes are induced by... 
Zebrafish | AHR2 | Intestine | Liver | Dioxin | CYP3A65 | CYTOCHROME-P450 | NUCLEAR RECEPTORS | INDUCTION | IDENTIFICATION | PREGNANE-X-RECEPTOR | GENE | ARYL-HYDROCARBON RECEPTOR | SIGNALING PATHWAY | PHARMACOLOGY & PHARMACY | TOXICOLOGY | LIGAND | EXPRESSION | Gene Expression Regulation, Enzymologic - drug effects | Aryl Hydrocarbon Hydroxylases - biosynthesis | Oxidoreductases, N-Demethylating - genetics | Liver - enzymology | Aryl Hydrocarbon Hydroxylases - genetics | Green Fluorescent Proteins - genetics | RNA, Messenger - biosynthesis | Liver - drug effects | Polychlorinated Dibenzodioxins - pharmacology | Receptors, Aryl Hydrocarbon - metabolism | Oxidoreductases, N-Demethylating - metabolism | Green Fluorescent Proteins - metabolism | Zebrafish Proteins - biosynthesis | Animals, Genetically Modified | Zebrafish Proteins - metabolism | Liver - metabolism | RNA, Messenger - genetics | Receptors, Aryl Hydrocarbon - genetics | In Situ Hybridization, Fluorescence | Zebrafish - genetics | Aryl Hydrocarbon Hydroxylases - metabolism | Animals | Green Fluorescent Proteins - biosynthesis | Zebrafish - metabolism | Liver - physiology | Oxidoreductases, N-Demethylating - biosynthesis | Zebrafish Proteins - genetics | Proteins | Herbicides | Cytochrome P-450 | Physiological aspects | Tryptophan | Genetic engineering | Genetic transcription | Xenobiotics | Index Medicus | DIOXIN | KYNURENINE | TRYPTOPHAN | ANTIBIOTICS | DEXAMETHASONE | METABOLISM | DNA | GENES | LIVER | TRANSCRIPTION | INTESTINES | 60 APPLIED LIFE SCIENCES
Journal Article
Journal Article
Journal Article
Thorax, ISSN 0040-6376, 01/2011, Volume 66, Issue 10, pp. 894 - 902
Background Cigarette smoking is a major risk factor for chronic obstructive pulmonary disease (COPD) and COPD severity. Previous genome-wide association... 
NICOTINE DEPENDENCE | OBSTRUCTIVE PULMONARY-DISEASE | IMPUTATION | METAANALYSIS | VARIANTS | RESPIRATORY SYSTEM | LOCI | CIGARETTE | INTERVENTION | EPIDEMIOLOGY | CESSATION | Cytochrome P-450 CYP2A6 | United States - epidemiology | Age Factors | Humans | Middle Aged | Aryl Hydrocarbon Hydroxylases - genetics | Male | Pulmonary Disease, Chronic Obstructive - epidemiology | Incidence | Dopamine beta-Hydroxylase - metabolism | Female | Pulmonary Disease, Chronic Obstructive - metabolism | Pulmonary Disease, Chronic Obstructive - genetics | Genetic Predisposition to Disease | Genotype | Smoking - genetics | Aryl Hydrocarbon Hydroxylases - metabolism | DNA - genetics | Smoking - metabolism | Dopamine beta-Hydroxylase - genetics | Smoking - epidemiology | Aged | Polymorphism, Single Nucleotide | Genome-Wide Association Study - methods | Smoking Cessation | Genetic aspects | Forecasts and trends | Single nucleotide polymorphisms | Research | Demographic aspects | Smoking | Smoking cessation | Genotype & phenotype | Disease | Mortality | Chronic obstructive pulmonary disease | Genomes | Behavior | Health risk assessment | Chromosomes | Age | Nicotine | Drug addiction | Dopamine beta -monooxygenase | Cytochrome P450 | Single-nucleotide polymorphism | Cigarette smoking | Risk factors | chromosome 6 | chromosome 2 | Acetylcholine receptors | Obstructive lung disease | Histocompatibility antigen HLA | Index Medicus
Journal Article
Pharmacogenetics and Genomics, ISSN 1744-6872, 02/2006, Volume 16, Issue 2, pp. 101 - 110
Journal Article
American Journal of Medical Genetics Part C: Seminars in Medical Genetics, ISSN 1552-4868, 03/2014, Volume 166, Issue 1, pp. 45 - 55
Journal Article
JAMA, ISSN 0098-7484, 10/2011, Volume 306, Issue 16, pp. 1765 - 1774
CONTEXT Despite dual antiplatelet therapy, stent thrombosis remains a devastating and unpredictable complication of percutaneous coronary intervention (PCI).... 
LONG-TERM | MEDICINE, GENERAL & INTERNAL | CYP2C19 GENOTYPE | HEART-DISEASE | THERAPY | METAANALYSIS | PARAOXONASE-1 | RISK | POLYMORPHISM | CLOPIDOGREL-TREATED PATIENTS | PLATELET REACTIVITY | Thrombosis - chemically induced | Prognosis | Humans | Middle Aged | Aryl Hydrocarbon Hydroxylases - genetics | Male | Case-Control Studies | Angioplasty, Balloon, Coronary | DNA - analysis | Ticlopidine - adverse effects | Female | Integrin beta3 - genetics | France | Platelet Aggregation Inhibitors - adverse effects | Proton Pump Inhibitors - adverse effects | Genetic Predisposition to Disease | Risk Factors | Genotype | Ticlopidine - analogs & derivatives | Coronary Angiography | Coronary Artery Disease - diagnostic imaging | Coronary Artery Disease - therapy | ATP-Binding Cassette, Sub-Family B, Member 1 - genetics | Cytochrome P-450 CYP2C19 | Thrombosis - genetics | ATP Binding Cassette Transporter, Sub-Family B | Aged | Polymorphism, Single Nucleotide | Stents - adverse effects | Aggregation | Blood platelets | Causes of | Coronary thrombosis | Genetic aspects | Dosage and administration | Drug therapy | Medical imaging | Stents | Thrombosis | Genes | Medical prognosis | Risk factors | Index Medicus | Abridged Index Medicus | Heart | Protons | Phospholipase A2 | Statistical analysis | thromboembolism | complications | Diabetes mellitus | Sex | DNA | Implants | Clopidogrel | Models | Genetic factors | Ventricle | Lesions | intervention | Age | Genotypes
Journal Article
Pharmacogenetics and Genomics, ISSN 1744-6872, 12/2007, Volume 17, Issue 12, pp. 1057 - 1064
Journal Article
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 06/2010, Volume 55, Issue 25, pp. 2804 - 2812
Journal Article