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Applied Physiology, Nutrition, and Metabolism, ISSN 1715-5312, 2017, Volume 42, Issue 1, pp. 77 - 83
Diet soda consumption has not been associated with tangible weight loss. Aspartame (ASP) commonly substitutes sugar and one of its breakdown products is... 
édulcorants non nutritifs | non-nutritive sweeteners | alcaline phosphatase intestinale | insulinorésistance induite par la diète | aspartame | noncaloric sweeteners | insulinorésistance | diet-induced insulin resistance | édulcorants non caloriques | obésité | intestinal alkaline phosphatase | insulin resistance | obesity | Aspartame | Non-nutritive sweeteners | Obesity | Noncaloric sweeteners | Intestinal alkaline phosphatase | Diet-induced insulin resistance | Insulin resistance | SPORT SCIENCES | METABOLIC SYNDROME | PHYSIOLOGY | ARTIFICIAL SWEETENERS | HIGH-INTENSITY SWEETENERS | NECROSIS-FACTOR-ALPHA | ENERGY-INTAKE | BODY-WEIGHT | NUTRITION & DIETETICS | INSULIN-RESISTANCE | SUGAR-SWEETENED BEVERAGES | NONNUTRITIVE SWEETENERS | CONSUMPTION | Glucose Intolerance - metabolism | Metabolic Syndrome - etiology | Intestinal Mucosa - metabolism | Tumor Necrosis Factor-alpha - blood | Alkaline Phosphatase - metabolism | Diet, High-Fat - adverse effects | Male | Metabolic Syndrome - metabolism | Obesity - blood | Glucose Intolerance - blood | Intestine, Small - enzymology | Non-Nutritive Sweeteners - adverse effects | Metabolic Syndrome - blood | Glucose Intolerance - etiology | Biotransformation | Intestinal Mucosa - enzymology | Obesity - etiology | Non-Nutritive Sweeteners - metabolism | Weight Gain | Phenylalanine - metabolism | Blood Glucose - analysis | Enzyme Inhibitors - metabolism | Aspartame - metabolism | Aspartame - adverse effects | Mice, Inbred C57BL | Insulin Resistance | Biomarkers - blood | Obesity - metabolism | Alkaline Phosphatase - antagonists & inhibitors | Animals | Intestine, Small - metabolism
Journal Article
Nutrition Research, ISSN 0271-5317, 2017, Volume 41, pp. 47 - 55
Abstract Dietary intake of fructose corn syrup in sweetened beverages is associated with the development of metabolic syndrome and obesity. We hypothesized... 
Gastroenterology and Hepatology | Aspartame | Adipocytokines | Oxidative stress | Sweetened beverages | Metabolic syndrome | Gene expression | RAT-LIVER | INDUCED METABOLIC SYNDROME | STELLATE CELLS | COLA BEVERAGES | BODY-WEIGHT | NUTRITION & DIETETICS | FRUCTOSE CORN SYRUP | ADIPONECTIN | INSULIN-RESISTANCE | SUGAR-SWEETENED BEVERAGES | Rats, Wistar | Glutathione - metabolism | Antioxidants - metabolism | Alkaline Phosphatase - metabolism | Male | Carbonated Beverages - adverse effects | PPAR gamma - metabolism | Obesity - blood | Adipokines - blood | Metabolic Syndrome - blood | Nutritive Sweeteners - adverse effects | Hyperglycemia - diagnosis | Liver - drug effects | Malondialdehyde - blood | Obesity - diagnosis | Superoxide Dismutase - metabolism | PPAR gamma - genetics | Glutathione Peroxidase - metabolism | High Fructose Corn Syrup - adverse effects | Aspartame - adverse effects | Liver - metabolism | Rats | Biomarkers - blood | Aspartate Aminotransferases - metabolism | Catalase - metabolism | Animals | Hyperglycemia - blood | Metabolic Syndrome - diagnosis | Lipid Metabolism - drug effects | Alanine Transaminase - metabolism | Oxidative Stress - drug effects | Antioxidants | Hyperglycemia | Carbonated beverages | Low density lipoproteins | Leptin | Development and progression | Fructose | Benzoic acid | Phosphates | Phosphatases | RNA | Liver | Superoxide | Glutathione transferase | Peroxides | Peroxidase
Journal Article
Journal of Food and Drug Analysis, ISSN 1021-9498, 04/2018, Volume 26, Issue 2, pp. 903 - 916
Many controversial reports are available on the use of aspartame as it releases methanol as one of its metabolite during metabolism. The present study proposes... 
Aspartame | Oxidative stress | Memory | Free radical | Folate deficient rat model | ACETYLCHOLINESTERASE ACTIVITY | CELLS | OPTIC-NERVE | PROTECTION | FOOD SCIENCE & TECHNOLOGY | TOXICITY | FREE-RADICALS | L-ARGININE | NITRIC-OXIDE | PHARMACOLOGY & PHARMACY | EXPRESSION | BRAIN | Oxidative Stress | Rats, Wistar | Sweetening Agents - metabolism | Sweetening Agents - adverse effects | Receptors, N-Methyl-D-Aspartate - metabolism | Male | Extracellular Signal-Regulated MAP Kinases - metabolism | Extracellular Signal-Regulated MAP Kinases - genetics | Methanol - adverse effects | Receptors, N-Methyl-D-Aspartate - genetics | Brain - metabolism | Female | Calcium-Calmodulin-Dependent Protein Kinase Type 2 - metabolism | Signal Transduction | Aspartame - metabolism | Aspartame - adverse effects | Rats | Calcium-Calmodulin-Dependent Protein Kinase Type 2 - genetics | Methanol - metabolism | Cyclic AMP Response Element-Binding Protein - genetics | Animals | Nitric Oxide Synthase Type I - metabolism | Cyclic AMP Response Element-Binding Protein - metabolism | Nitric Oxide - metabolism | Apoptosis | Nitric Oxide Synthase Type II - metabolism | Brain | Corticosterone | Body weight | Nervous system | Glutamic acid receptors | Proteins | Artificial sweeteners | Signal transduction | Neurodegeneration | Vitamin B | Inhibition | Methotrexate | Methanol | Enzymes | Free radicals | Albinism | Astrocytes | Shrinkage | Cyclic AMP response element-binding protein | Gene expression | Metabolism | Nitric-oxide synthase | Chemicals | Strain | Microglia | Nitric oxide | Morphology | Hippocampus | Phosphorylation | Laboratories | Cytology | mRNA | Metabolites | Esterase | Degeneration | Food | Neurons | Extracellular signal-regulated kinase | Vitamin deficiency | N-Methyl-D-aspartic acid receptors | Signaling | Brain research | Excitotoxicity | Acetylcholine | Ca2+/calmodulin-dependent protein kinase II
Journal Article
Neurotoxicity Research, ISSN 1029-8428, 4/2012, Volume 21, Issue 3, pp. 245 - 255
Journal Article
Journal Article
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 514, Issue 7521, pp. 181 - 186
Journal Article
International Journal of Toxicology, ISSN 1091-5818, 7/2014, Volume 33, Issue 4, pp. 332 - 341
Aspartame is one of the most widely used artificial sweeteners globally. Data concerning acute neurotoxicity of aspartame is controversial, and knowledge on... 
apoptosis | phenylalanine | aspartame | monoamines | SPRAGUE-DAWLEY RATS | OXIDATIVE STRESS | L-CYSTEINE | FRONTAL-CORTEX | NEUTRAL AMINO-ACIDS | PUMP ACTIVITY | K+-ATPASE ACTIVITY | CELL-DEATH | IN-VIVO | Na+-K+-ATPase | PHARMACOLOGY & PHARMACY | TOXICOLOGY | Tyrosine 3-Monooxygenase - metabolism | Serotonin Antagonists - administration & dosage | Rats, Wistar | Tyrosine - agonists | Male | Water-Electrolyte Imbalance - etiology | Corpus Striatum - metabolism | Dopamine Antagonists - administration & dosage | Tryptophan - metabolism | Cerebral Cortex - metabolism | Non-Nutritive Sweeteners - adverse effects | Toxicity Tests, Chronic | Serotonin Antagonists - adverse effects | Aspartame - administration & dosage | Neurons - metabolism | Corpus Striatum - enzymology | Tryptophan - antagonists & inhibitors | Nerve Tissue Proteins - antagonists & inhibitors | Cerebral Cortex - enzymology | Sodium-Potassium-Exchanging ATPase - antagonists & inhibitors | Phenylalanine - metabolism | Non-Nutritive Sweeteners - administration & dosage | Aspartame - adverse effects | Tyrosine 3-Monooxygenase - antagonists & inhibitors | Random Allocation | Phenylalanine - agonists | Nerve Tissue Proteins - metabolism | Neurotoxicity Syndromes - etiology | Water-Electrolyte Imbalance - metabolism | Neurotoxicity Syndromes - enzymology | Sodium-Potassium-Exchanging ATPase - metabolism | Tyrosine - metabolism | Animals | Dopamine Antagonists - adverse effects | Neurons - enzymology | Neurotoxicity Syndromes - metabolism | Water-Electrolyte Imbalance - enzymology | Apoptosis
Journal Article