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index medicus (158) 158
biochemistry & molecular biology (104) 104
animals (82) 82
humans (76) 76
aspartate glutamate carrier (62) 62
mitochondria (60) 60
aspartate-glutamate carrier (48) 48
cell biology (44) 44
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biophysics (42) 42
ii citrullinemia (42) 42
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glutamate (32) 32
citrin (31) 31
carrier proteins - metabolism (30) 30
adp/atp carrier (29) 29
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kinetics (26) 26
mitochondrial membrane transport proteins (26) 26
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aspartate/glutamate antiporter (25) 25
calcium-binding proteins - deficiency (25) 25
organic anion transporters - deficiency (25) 25
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slc25a13 (25) 25
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genetics & heredity (24) 24
neurosciences (24) 24
mitochondrial membrane transport proteins - genetics (23) 23
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citrullinemia - genetics (22) 22
fatty acids (22) 22
aspartate/glutamate carrier (21) 21
bovine heart-mitochondria (21) 21
carrier (21) 21
mice (21) 21
mitochondrion (21) 21
mitochondrial proteins - genetics (19) 19
biochemistry, general (18) 18
infant (18) 18
medicine, research & experimental (18) 18
urea cycle (18) 18
biochemistry (17) 17
calcium (17) 17
mitochondria, liver - metabolism (17) 17
mutations (17) 17
uncoupling (17) 17
carrier proteins - chemistry (16) 16
infant, newborn (16) 16
liver (16) 16
membrane transport proteins - genetics (16) 16
saccharomyces-cerevisiae (16) 16
adult (15) 15
adult-onset type ii citrullinemia (15) 15
analysis (15) 15
aralar (15) 15
biological transport (15) 15
heart-mitochondria (15) 15
liver mitochondria (15) 15
molecular sequence data (15) 15
niccd (15) 15
phosphate carrier (15) 15
proteins (15) 15
uncoupling protein (15) 15
antiporters - metabolism (14) 14
aspartic acid - metabolism (14) 14
carrier proteins - genetics (14) 14
physiology (14) 14
amino acid sequence (13) 13
amino acids (13) 13
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life sciences (13) 13
mitochondrial aspartate glutamate (13) 13
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uncoupling agents - pharmacology (12) 12
adp/atp antiporter (11) 11
calcium - metabolism (11) 11
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cholestasis, intrahepatic - genetics (11) 11
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glutamic acid - metabolism (11) 11
liver-transplantation (11) 11
mice, knockout (11) 11
mitochondrial proteins - metabolism (11) 11
neurons - metabolism (11) 11
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International Journal of Biochemistry and Cell Biology, ISSN 1357-2725, 03/2015, Volume 60, pp. 157 - 166
The aspartate/glutamate carrier isoform 1 is an essential mitochondrial transporter that exchanges intramitochondrial aspartate and cytosolic glutamate across... 
Aspartate/glutamate carrier | Ca2 | CREB | CREBCa | ACETYL-L-ASPARTATE | NERVOUS-SYSTEM | TRANSPORTER FAMILY SLC25 | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | SH-SY5Y NEUROBLASTOMA-CELLS | ELEMENT-BINDING PROTEIN | CITRATE CARRIER | MYELIN LIPID-SYNTHESIS | CELL BIOLOGY | N-ACETYLASPARTATE | RAT-BRAIN | Mitochondrial Membrane Transport Proteins - metabolism | Calcium - metabolism | Humans | Aggrecans - metabolism | Neuregulin-1 - pharmacology | Aggrecans - genetics | Mitochondrial Membrane Transport Proteins - genetics | Cyclic AMP Response Element-Binding Protein - genetics | Chromatin Immunoprecipitation | Signal Transduction - drug effects | Cell Differentiation - drug effects | Cyclic AMP Response Element-Binding Protein - metabolism | Cell Line, Tumor | Protein Binding | Signal Transduction - physiology | Electrophoretic Mobility Shift Assay | Gene expression | Neurons | Genes | Index Medicus | T-CREB, total-cAMP-response-element-binding protein db-cAMP, dibutyryl-cAMP | siCREB, siRNA targeting CREB | IFNγ, interferon gamma | EMSA, electrophoreticmobility-shift assay | TNFα, tumor necrosis factor alpha | SAP97, synapse-associated protein-97 | IBMX, isobutylmethylxanthine | ChIP, chromatin immunoprecipitation | P-CREB, phospho-cAMP-response-element-binding protein | NAA, N-acetylaspartate | SYP, synaptophysin | PKA, cAMP-dependent protein kinase | Aspartate | glutamate carrier | BAPTA-AM, 1,2-bis(2-aminophenoxy) ethane-N,N,N′,N′-tetraacetic acid tetrakis(acetoxymethyl ester) | Aβ, β-amyloid | WB, Western-blotting | siRNA, small interfering RNA | glutamate carrier isoform 1 | NRG-1, neuregulin-1 | LUC, luciferase | AGC1, aspartate | APP, amyloid precursor protein
Journal Article
Biochemical Journal, ISSN 0264-6021, 12/2009, Volume 424, Issue 3, pp. 459 - 466
Journal Article
Journal Article
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, ISSN 0925-4439, 06/2017, Volume 1863, Issue 6, pp. 1422 - 1435
The mitochondrial aspartate-glutamate carrier isoform 1 (AGCI) catalyzes a Ca2+-stimulated export of aspartate to the cytosol in exchange for glutamate, and is... 
AGC1 deficiency | BIOCHEMISTRY & MOLECULAR BIOLOGY | SUBCELLULAR-LOCALIZATION | CITRIN | ASTROCYTES | Neurodegenerative disorders | DEFICIENCY | Mitochondrial aspartate/glutamate carder | BIOPHYSICS | Brain hypomyelination | GLUCOSE | CALCIUM | N-Acetylaspartate synthesis | ENERGY-METABOLISM | EXPRESSION | RECONSTITUTION | BRAIN
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 04/2007, Volume 101, Issue 1, pp. 120 - 131
Journal Article
Journal Article
Journal Article
Developmental Brain Research, ISSN 0165-3806, 06/2003, Volume 143, Issue 1, pp. 33 - 46
Aralar1 and citrin are two isoforms of the mitochondrial carrier of aspartate-glutamate (AGC), a calcium regulated carrier, which is important in the... 
Calcium dependent mitochondrial carrier | Malate-aspartate NADH shuttle | Mitochondria | Neuron maturation | Brain development | Aspartate-glutamate carrier | brain development | calcium dependent mitochondrial carrier | mitochondria | SUBCELLULAR-LOCALIZATION | CITRIN | CYTOCHROME-OXIDASE | DEVELOPMENTAL BIOLOGY | aspartate-glutamate carrier | HIPPOCAMPAL-NEURONS | NEUROSCIENCES | MESSENGER-RNA LEVELS | GENE | malate-aspartate NADH shuttle | CALCIUM | 3-(4,5-DIMETHYLTHIAZOL-2-YL)-2,5-DIPHENYLTETRAZOLIUM BROMIDE MTT | II CITRULLINEMIA | RAT-BRAIN | neuron maturation | Blotting, Southern | Brain - embryology | Spinal Cord - drug effects | Spinal Cord - metabolism | Rats, Wistar | Calcium - metabolism | Embryo, Mammalian | Amino Acid Transport Systems, Acidic - metabolism | Stem Cells - metabolism | Organic Anion Transporters - metabolism | Brain - metabolism | Proton-Translocating ATPases - metabolism | Tissue Distribution | Mitochondrial Membrane Transport Proteins | In Situ Hybridization | Protein Isoforms - metabolism | Stem Cells - enzymology | Time Factors | Gene Expression Regulation, Developmental | Mitochondrial Proteins - metabolism | Phosphoric Monoester Hydrolases - pharmacology | Membrane Transport Proteins - metabolism | Neurons - metabolism | Lactic Acid - pharmacology | DNA, Mitochondrial - biosynthesis | Calcium-Binding Proteins - metabolism | Cell Line | Blotting, Western - methods | Glutamic Acid - pharmacology | Malates - pharmacology | Cells, Cultured | Rats | Antiporters - metabolism | Mitochondria - metabolism | Tetrazolium Salts - pharmacology | Brain - drug effects | Spinal Cord - embryology | Animals | Succinic Acid - pharmacology | Neuroglia - metabolism | Mice | Thiazoles - pharmacology | Index Medicus
Journal Article
Journal Article
Pediatrics, ISSN 0031-4005, 01/2019, Volume 143, Issue 1, p. e20181931
Patients with FTTDCD should be managed carefully because the condition can lead to HCC. We report the case of a 6-year-old boy with citrin deficiency and... 
II CITRULLINEMIA | PEDIATRICS | ASPARTATE GLUTAMATE CARRIER | MUTATIONS | HEPATITIS | ADAPTATION
Journal Article
Molecular Genetics and Metabolism, ISSN 1096-7192, 2009, Volume 97, Issue 1, pp. 21 - 26
Neonatal intrahepatic cholestasis caused by citrin deficiency (NICCD) shows diverse metabolic abnormalities such as urea cycle dysfunction together with... 
Carbohydrates | Oxidative stress | Hypercholesterolemia | Neonatal intrahepatic cholestasis caused by citrin deficiency | Adult-onset type II citrullinemia | Aspartate/glutamate carrier isoform 2-citrin | Amino acids | Silent period | MEDICINE, RESEARCH & EXPERIMENTAL | INTRACELLULAR REDOX STATE | SERUM | IDENTIFICATION | CITRIN DEFICIENCY | DENSITY-LIPOPROTEIN | DISEASE | ENDOCRINOLOGY & METABOLISM | GENETICS & HEREDITY | NITRIC-OXIDE | II CITRULLINEMIA | MUTATIONS | MANIFESTATIONS | Amino Acids - blood | Liver - pathology | Biomarkers - urine | Oxidative Stress | Humans | Child, Preschool | Infant | Male | Liver - physiopathology | Carbohydrates - blood | Mitochondrial Membrane Transport Proteins | Membrane Transport Proteins - deficiency | Fasting - blood | Citrullinemia - blood | Female | Urea - metabolism | Mitochondrial Proteins - deficiency | Child | Liver Function Tests | Hypercholesterolemia - blood | Japan | Vitamin E - blood | Lipid Metabolism | Citrullinemia - complications | Apolipoproteins - blood | Asian Continental Ancestry Group | Citrullinemia - physiopathology | Hypercholesterolemia - complications | Hypercholesterolemia - physiopathology | Nitric Oxide - metabolism | Medical colleges | Blood sugar | Guanosine | Low density lipoproteins | Nitrogen compounds | Glutamate | Cholesterol | Lactates | Urea | Metabolites | Analysis | Nitric oxide | Medical genetics | Children | Galactose | Acids | Index Medicus
Journal Article