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Journal Article
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 01/2008, Volume 177, Issue 1, pp. 27 - 34
Rationale: Invasive aspergillosis (IA) is an important cause of mortality in patients with hematologic malignancies. However, IA appears to be gaining a... 
Bronchoscopy | Aspergillus | Immunosuppression | Galactomannan | Intensive care unit | RESPIRATORY-TRACT | AUTOPSY | ASSAY | MANAGEMENT | galactomannan | ENZYME-IMMUNOASSAY | immunosuppression | TRANSPLANT RECIPIENTS | bronchoscopy | FUNGAL-INFECTIONS | INVASIVE PULMONARY ASPERGILLOSIS | RESPIRATORY SYSTEM | intensive care unit | CRITICALLY-ILL PATIENTS | ANTIGEN | CRITICAL CARE MEDICINE | Lung - microbiology | Pneumonia, Ventilator-Associated - mortality | Predictive Value of Tests | Lung Diseases, Fungal - diagnosis | Prospective Studies | Humans | Middle Aged | Cross Infection - mortality | Aspergillosis - diagnosis | Male | Opportunistic Infections - mortality | Tomography, X-Ray Computed | Cause of Death | Lung Diseases, Fungal - microbiology | Bronchoalveolar Lavage Fluid - microbiology | Cross Infection - pathology | Aspergillosis - pathology | Lung Diseases, Fungal - pathology | Aspergillosis - mortality | Adult | Female | Mycological Typing Techniques | Diagnosis, Differential | Intensive Care Units | Lung - pathology | Hospital Mortality | Survival Rate | Pneumonia, Ventilator-Associated - diagnosis | Lung Diseases, Fungal - mortality | Opportunistic Infections - diagnosis | Opportunistic Infections - microbiology | Pneumonia, Ventilator-Associated - microbiology | Cross Infection - microbiology | Mannans - blood | Aspergillosis - microbiology | Cross Infection - diagnosis | Aged | Pneumonia, Ventilator-Associated - pathology | Opportunistic Infections - pathology
Journal Article
Journal Article
Nature, ISSN 0028-0836, 2008, Volume 451, Issue 7175, pp. 211 - 215
Half a century ago, chronic granulomatous disease ( CGD) was first described as a disease fatally affecting the ability of children to survive infections.... 
GAMMA | DENDRITIC CELLS | IDO | TOLERANCE | MULTIDISCIPLINARY SCIENCES | INDOLEAMINE 2,3-DIOXYGENASE | HOST-DEFENSE | INFECTION | DELTA-T-CELLS | NF-KAPPA-B | IL-17 PRODUCTION | Indoleamine-Pyrrole 2,3,-Dioxygenase - genetics | Indoleamine-Pyrrole 2,3,-Dioxygenase - metabolism | Inflammation - pathology | Reactive Oxygen Species - metabolism | Kynurenine - therapeutic use | T-Lymphocytes - enzymology | Granulomatous Disease, Chronic - metabolism | NADPH Oxidases - metabolism | Granulomatous Disease, Chronic - complications | Tryptophan - metabolism | Lung Diseases, Fungal - microbiology | Inflammation - complications | NADPH Oxidases - deficiency | Inflammation - metabolism | Aspergillosis - pathology | Lung Diseases, Fungal - pathology | Inflammation - drug therapy | Superoxides - metabolism | Aspergillus fumigatus - physiology | NADPH Oxidases - genetics | Kynurenine - metabolism | T-Lymphocytes - pathology | Granulomatous Disease, Chronic - pathology | Aspergillosis - complications | Disease Models, Animal | Lung - pathology | Lung Diseases, Fungal - immunology | Interferon-gamma - therapeutic use | Mice, Inbred C57BL | Lung Diseases, Fungal - complications | Receptors, Antigen, T-Cell, gamma-delta - immunology | Interleukin-17 - deficiency | Mice, Knockout | Interleukin-17 - metabolism | Animals | Interferon-gamma - immunology | Aspergillosis - microbiology | T-Lymphocytes - immunology | Mice | Granulomatous Disease, Chronic - drug therapy | Chronic Disease | Lung - immunology | Aspergillosis - immunology | Complications and side effects | Chronic granulomatous disease | Care and treatment | Metabolic diseases | Inflammation | Research | Risk factors | Biomedical research | Genetic disorders | Immunology | Rodents | Infections | Metabolism | Inflammatory diseases
Journal Article
Journal of immunology (Baltimore, Md. : 1950), ISSN 0022-1767, 07/2017, Volume 199, Issue 2, pp. 624 - 632
The polysaccharide-rich fungal cell wall provides pathogen-specific targets for antifungal therapy and distinct molecular patterns that stimulate protective or... 
Aspergillus fumigatus - drug effects | Antifungal Agents - adverse effects | Lipopeptides - pharmacology | Lipopeptides - therapeutic use | Humans | Eosinophils - immunology | Antifungal Agents - therapeutic use | Bronchoalveolar Lavage Fluid - microbiology | Invasive Pulmonary Aspergillosis - physiopathology | Chitin - metabolism | Echinocandins - immunology | Echinocandins - pharmacology | Antifungal Agents - pharmacology | Invasive Pulmonary Aspergillosis - drug therapy | Invasive Pulmonary Aspergillosis - immunology | Chitin - chemistry | Receptors, Antigen, T-Cell, gamma-delta - immunology | Lipopeptides - immunology | Aspergillus fumigatus - chemistry | Eosinophils - physiology | Animals | Echinocandins - adverse effects | Aspergillus fumigatus - immunology | Invasive Pulmonary Aspergillosis - microbiology | Lipopeptides - adverse effects | Echinocandins - therapeutic use | T-Lymphocytes - immunology | Mice | Bronchoalveolar Lavage Fluid - chemistry | Antifungal Agents - immunology | Chitin - immunology | Therapy | Fungicides | Syngeneic grafts | Prophylaxis | Lung transplantation | Immune clearance | Lymphocytes T | Immunity | Recruitment | Respiratory tract | Proteins | Fungi | Glucan | Lymphocytes | Bronchoalveolar lavage | Caspofungin | Peroxidase | Inhibition | Alveoli | Neutropenia | Pathogens | Cell walls | Antifungal agents | Bronchus | Chitin | Patients | RAG1 protein | Aspergillosis | In vivo methods and tests | gammadelta T cells | invasive aspergillosis | echinocandin | eosinophils | Aspergillus fumigatus | caspofungin | lung immune responses | chitin
Journal Article
Canadian Respiratory Journal, ISSN 1198-2241, 2016, Volume 2016, pp. 8715024 - 8
Background. The aim of this study was to assess the utility of open lung biopsy in patients with hypoxic respiratory failure of unknown etiology admitted to an... 
SURVIVAL | MANAGEMENT | RESPIRATORY SYSTEM | DISTRESS-SYNDROME | DISEASE | SEVERITY | ARDS | Lung Diseases, Interstitial - pathology | Pneumonia, Pneumocystis - diagnosis | Humans | Middle Aged | Critical Illness | Male | Pneumocystis carinii | Cytomegalovirus Infections - complications | Neoplasms - diagnosis | Adrenal Cortex Hormones - therapeutic use | Pneumonia - diagnosis | Cytomegalovirus Infections - pathology | Odds Ratio | Tuberculosis, Miliary - diagnosis | Hypoxia - etiology | Survival Rate | Cytomegalovirus Infections - diagnosis | Invasive Pulmonary Aspergillosis - diagnosis | Tuberculosis, Miliary - complications | Vasculitis - diagnosis | Hypoxia - pathology | Invasive Pulmonary Aspergillosis - complications | Cohort Studies | Pneumonia, Pneumocystis - complications | Multivariate Analysis | Respiratory Insufficiency - diagnosis | Vasculitis - pathology | Pneumonia - pathology | Hypoxia - mortality | Respiratory Insufficiency - etiology | Tuberculosis, Miliary - pathology | Vasculitis - complications | Neoplasms - complications | Lung Diseases, Interstitial - diagnosis | Female | Retrospective Studies | Intensive Care Units | Lung - pathology | Hospital Mortality | Respiratory Insufficiency - mortality | Pneumonia, Pneumocystis - pathology | Hypoxia - diagnosis | Lung Diseases, Interstitial - complications | Respiratory Insufficiency - pathology | Biopsy | Pneumonia - complications | Aged | Neoplasms - pathology | Invasive Pulmonary Aspergillosis - pathology
Journal Article
Cell Reports, ISSN 2211-1247, 08/2017, Volume 20, Issue 7, pp. 1667 - 1680
The interleukin 17 (IL-17) cytokine and receptor family is central to antimicrobial resistance and inflammation in the lung. Mice lacking IL-17A, IL-17F, or... 
IL-17F/IL-17RC axis | Th17 immunity | allergy | ABPA | respiratory infections | INTERLEUKIN-17 RECEPTOR | IL-17 RECEPTOR | SEVERE ASTHMA | INFLAMMATION | PROSTATE-CANCER | DOUBLE-BLIND | CYSTIC-FIBROSIS | CHRONIC MUCOCUTANEOUS CANDIDIASIS | CUTTING EDGE | TH17 CELLS | CELL BIOLOGY | Lung - microbiology | Staphylococcal Infections - pathology | Humans | Receptors, Interleukin-17 - immunology | Interleukin-17 - immunology | Hypersensitivity - immunology | Receptors, Interleukin-17 - genetics | Receptors, Interleukin-17 - deficiency | Respiratory Mucosa - pathology | Respiratory Mucosa - microbiology | Aspergillosis - pathology | Hypersensitivity - microbiology | Respiratory Mucosa - immunology | Female | Hypersensitivity - genetics | Protein Isoforms - deficiency | Pseudomonas - immunology | Staphylococcal Infections - microbiology | Disease Models, Animal | Lung - pathology | Staphylococcal Infections - genetics | Aspergillus - immunology | Disease Susceptibility | Signal Transduction | Staphylococcal Infections - immunology | Mice, Inbred C57BL | Aspergillosis - genetics | Gene Expression Regulation | Interleukin-17 - genetics | Epithelial Cells - pathology | Interleukin-17 - deficiency | Pseudomonas Infections - microbiology | Mice, Knockout | Pseudomonas Infections - genetics | Pseudomonas Infections - immunology | Animals | Hypersensitivity - pathology | Epithelial Cells - immunology | Epithelial Cells - microbiology | Aspergillosis - microbiology | Pseudomonas Infections - pathology | Staphylococcus aureus - immunology | Mice | Protein Isoforms - immunology | Lung - immunology | Aspergillosis - immunology | Protein Isoforms - genetics
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