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1. Full Text Deciphering the role of the chitin synthase families 1 and 2 in the in vivo and in vitro growth of Aspergillus fumigatus by multiple gene targeting deletion
by Muszkieta, Laetitia and Aimanianda, Vishukumar and Mellado, Emilia and Gribaldo, Simonetta and Alcàzar‐Fuoli, Laura and Szewczyk, Edyta and Prevost, Marie‐Christine and Latgé, Jean‐Paul
Cellular microbiology, ISSN 1462-5814, 12/2014, Volume 16, Issue 12, pp. 1784 - 1805
Life Sciences & Biomedicine | Microbiology | Science & Technology | Cell Biology | Gene Targeting | Sequence Deletion | Chitin Synthase - metabolism | Mycelium - cytology | Aspergillus fumigatus - enzymology | Spores, Fungal - cytology | Spores, Fungal - growth & development | Aspergillus fumigatus - genetics | Chitin Synthase - genetics | Animals | Aspergillosis - pathology | Aspergillosis - microbiology | Mycelium - growth & development | Survival Analysis | Aspergillus fumigatus - cytology | Genes, Fungal | Aspergillus fumigatus - growth & development | Mice | Disease Models, Animal | Genetic research | Family | Chitin | Growth | Biosynthesis | Bacteriology | Index Medicus | Aspergillus fumigatus/enzymology | Aspergillus fumigatus/cytology | Spores, Fungal/cytology | Spores, Fungal/growth & development | Aspergillus fumigatus/growth & development | Aspergillus fumigatus/genetics | Life Sciences | Microbiology and Parasitology | Aspergillosis/pathology | Chitin Synthase/genetics | Chitin Synthase/metabolism | Mycelium/cytology | Aspergillosis/microbiology | Mycelium/growth & development
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2. Full Text GH16 and GH81 family β‐(1,3)‐glucanases in Aspergillus fumigatus are essential for conidial cell wall morphogenesis
by Mouyna, Isabelle and Aimanianda, Vishukumar and Hartl, Lukas and Prevost, Marie‐christine and Sismeiro, Odile and Dillies, Marie‐Agnès and Jagla, Bernd and Legendre, Rachel and Coppee, Jean‐Yves and Latgé, Jean‐Paul
Cellular microbiology, ISSN 1462-5814, 09/2016, Volume 18, Issue 9, pp. 1285 - 1293
Aspergillus fumigatus - ultrastructure | Glycoside Hydrolases - physiology | Aspergillus fumigatus - enzymology | Spores, Fungal - growth & development | Glycosylation | Cell Wall - enzymology | Spores, Fungal - enzymology | Morphogenesis | Fungal Proteins - physiology | Spores, Fungal - ultrastructure | Aspergillus fumigatus - growth & development | Carbohydrate Conformation | Cell Wall - ultrastructure | Index Medicus | Cell Wall | Life Sciences | Microbiology and Parasitology | Glycoside Hydrolases | Spores, Fungal | Mycology | Fungal Proteins | Aspergillus fumigatus
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3. Full Text Structure-functional characterization of cytochrome P450 Sterol 14α-Demethylase (CYP51B) from aspergillus fumigatus and molecular basis for the development of antifungal drugs
by Hargrove, Tatiana Y and Wawrzak, Zdzislaw and Lamb, David C and Guengerich, F. Peter and Lepesheva, Galina I
The Journal of biological chemistry, ISSN 0021-9258, 09/2015, Volume 290, Issue 39, pp. 23916 - 23934
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Fungal Proteins - chemistry | Protein Structure, Tertiary | Cytochrome P-450 Enzyme System - chemistry | Aspergillus fumigatus - enzymology | Cytochrome P-450 Enzyme System - genetics | Voriconazole - chemistry | Fungal Proteins - antagonists & inhibitors | Structure-Activity Relationship | Catalysis | Fungal Proteins - genetics | Aspergillus fumigatus - genetics | Drug Resistance, Fungal | Index Medicus | Aspergillus | x-ray crystallography | enzyme inhibitor | sterol | drug design | sterol 14alpha-demethylase (CYP51) | cytochrome P450 | antifungal drugs | Enzymology
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4. Full Text Catalases of Aspergillus fumigatus
by Sophie Paris and Deborah Wysong and Jean-Paul Debeaupuis and Kazutoshi Shibuya and Bruno Philippe and Richard D. Diamond and Jean-Paul Latgé
Infection and Immunity, ISSN 0019-9567, 06/2003, Volume 71, Issue 6, pp. 3551 - 3562
Infectious Diseases | Immunology | Life Sciences & Biomedicine | Science & Technology | Fundamental and applied biological sciences. Psychology | Replicative cycle, interference, host-virus relations, pathogenicity, miscellaneous strains | Miscellaneous | Microbiology | Mycology | Biological and medical sciences | Virology | Amino Acid Sequence | Fungal Proteins - physiology | Phenotype | Catalase - genetics | Catalase - physiology | Humans | Mycelium - enzymology | Aspergillus fumigatus - enzymology | Cloning, Molecular | Molecular Sequence Data | Catalase - chemistry | Index Medicus | Fungal and Parasitic Infections
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5. Full Text Characterization of a new β(1-3)-glucan branching activity of aspergillus fumigatus
by Gastebois, Amandine and Mouyna, Isabelle and Simenel, Catherine and Clavaud, Cécile and Coddeville, Bernadette and Delepierre, Muriel and Latgé, Jean-Paul and Fontaine, Thierry
The Journal of biological chemistry, ISSN 0021-9258, 01/2010, Volume 285, Issue 4, pp. 2386 - 2396
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Chromatography, High Pressure Liquid - methods | Gas Chromatography-Mass Spectrometry | Electrophoresis, Polyacrylamide Gel | Aspergillus fumigatus - enzymology | Glucan Endo-1,3-beta-D-Glucosidase - genetics | beta-Glucans - isolation & purification | Glycosylation | Cell Wall - enzymology | Fungal Proteins - genetics | Aspergillus fumigatus - genetics | Blotting, Western | beta-Glucans - metabolism | Phenotype | Cellulases - metabolism | Glucan Endo-1,3-beta-D-Glucosidase - isolation & purification | Glucan Endo-1,3-beta-D-Glucosidase - metabolism | Nuclear Magnetic Resonance, Biomolecular | Mutation | Fungal Proteins - isolation & purification | Fungal Proteins - metabolism | Index Medicus | Cellulases | Mycology | Fungal Proteins | Chromatography, High Pressure Liquid | Glucan Endo-1,3-beta-D-Glucosidase | Cell Wall | Life Sciences | Microbiology and Parasitology | Aspergillus fumigatus | beta-Glucans | Enzyme Purification | Aspergillus | β(1–3)-Glucan Branching | NMR | Glycosyl Phosphatidylinositol Anchors | GH17 | Glycobiology and Extracellular Matrices | Bgt2p
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6. Full Text α1,3 Glucans Are Dispensable in Aspergillus fumigatus
by Christine Henry and Jean-Paul Latgé and Anne Beauvais
Eukaryotic Cell, ISSN 1535-9778, 01/2012, Volume 11, Issue 1, pp. 26 - 29
Mycelium - physiology | Mycelium - enzymology | Aspergillus fumigatus - enzymology | Fungal Proteins - genetics | Microbial Viability | Aspergillus fumigatus - genetics | Gene Knockout Techniques | Spores, Fungal - enzymology | Spores, Fungal - physiology | Phenotype | Genetic Engineering | Cell Wall - metabolism | Chitin - metabolism | Aspergillus fumigatus - physiology | Glucans - metabolism | Spores, Fungal - genetics | Mycelium - genetics | Glucosyltransferases - genetics | Index Medicus | Mycology | Fungal Proteins | Chitin | Cell Wall | Life Sciences | Microbiology and Parasitology | Spores, Fungal | Glucans | Glucosyltransferases | Aspergillus fumigatus | Mycelium
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7. Full Text β(1-3)Glucanosyltransferase Gel4p Is Essential for Aspergillus fumigatus
by Amandine Gastebois and Thierry Fontaine and Jean-Paul Latgé and Isabelle Mouyna
Eukaryotic Cell, ISSN 1535-9778, 08/2010, Volume 9, Issue 8, pp. 1294 - 1298
Life Sciences & Biomedicine | Microbiology | Mycology | Science & Technology | Gene Expression Regulation, Fungal | Chromatography, Ion Exchange | Mycelium - enzymology | Aspergillus fumigatus - enzymology | Glucan Endo-1,3-beta-D-Glucosidase - genetics | Fungal Proteins - genetics | Phylogeny | Aspergillus fumigatus - genetics | Gene Expression Regulation, Enzymologic | Glycosylphosphatidylinositols - metabolism | Gene Deletion | Mycelium - growth & development | Glucan Endo-1,3-beta-D-Glucosidase - metabolism | Aspergillus fumigatus - growth & development | Genes, Fungal - genetics | Mycelium - genetics | Fungal Proteins - metabolism | Genes, Essential - genetics | Index Medicus | Fungal Proteins | Glucan Endo-1,3-beta-D-Glucosidase | Genes, Essential | Life Sciences | Microbiology and Parasitology | Glycosylphosphatidylinositols | Genes, Fungal | Aspergillus fumigatus | Mycelium
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8. Full Text Crystal structure of the new investigational drug candidate VT-1598 in complex with Aspergillus fumigatus sterol 14α-demethylase provides insights into its broad-spectrum Antifungal Activity
by Hargrove, Tatiana Y and Garvey, Edward P and Hoekstra, William J and Yates, Christopher M and Wawrzak, Zdzislaw and Rachakonda, Girish and Villalta, Fernando and Lepesheva, Galina I and Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Antimicrobial agents and chemotherapy, ISSN 0066-4804, 07/2017, Volume 61, Issue 7
VT-1598 | Fungal infections | Inhibition | Sterol 14α-demethylase (CYP51) | Aspergillus fumigatus | X-ray structure | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Microbiology | Science & Technology | Antifungal Agents - pharmacology | Aspergillus fumigatus - drug effects | Fluconazole - pharmacology | Drugs, Investigational - pharmacology | Tetrazoles - pharmacology | Voriconazole - pharmacology | Sterol 14-Demethylase - genetics | Aspergillus fumigatus - enzymology | Aspergillus fumigatus - genetics | Ketoconazole - pharmacology | Candida albicans - genetics | Microbial Sensitivity Tests | Triazoles - pharmacology | Candida albicans - drug effects | Pyridines - pharmacology | Sterol 14-Demethylase - metabolism | Candida albicans - enzymology | Index Medicus
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9. Full Text First detection of TR34 L98H and TR46 Y121F T289A Cyp51 mutations in aspergillus fumigatus isolates in the United States
by Wiederhold, Nathan P and Gil, Veronica Garcia and Gutierrez, Felipe and Lindner, Jonathan R and Albataineh, Mohammad T and McCarthy, Dora I and Sanders, Carmita and Fan, Hongxin and Fothergill, Annette W and Sutton, Deanna A
Journal of clinical microbiology, ISSN 0095-1137, 01/2016, Volume 54, Issue 1, pp. 168 - 171
Life Sciences & Biomedicine | Microbiology | Science & Technology | Antifungal Agents - pharmacology | Aspergillus fumigatus - drug effects | Sterol 14-Demethylase - genetics | United States | Humans | Aspergillus fumigatus - enzymology | Mutation, Missense | Aspergillus fumigatus - genetics | Azoles - pharmacology | Microbial Sensitivity Tests | Aspergillus fumigatus - isolation & purification | Aspergillosis - microbiology | Drug Resistance, Fungal | Index Medicus | Mycology
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10. Full Text Xyloglucan breakdown by endo-xyloglucanase family 74 from Aspergillus fumigatus
by Damasio, André Ricardo de Lima and Damasio, André Ricardo de Lima and Rubio, Marcelo Ventura and Rubio, Marcelo Ventura and Gonçalves, Thiago Augusto and Gonçalves, Thiago Augusto and Persinoti, Gabriela Felix and Persinoti, Gabriela Felix and Segato, Fernando and Segato, Fernando and Prade, Rolf Alexander and Prade, Rolf Alexander and Contesini, Fabiano Jares and Contesini, Fabiano Jares and de Souza, Amanda Pereira and de Souza, Amanda Pereira and Buckeridge, Marcos Silveira and Buckeridge, Marcos Silveira and Squina, Fabio Marcio and Squina, Fabio Marcio
Applied microbiology and biotechnology, ISSN 0175-7598, 4/2017, Volume 101, Issue 7, pp. 2893 - 2903
Life Sciences | Biotechnology | Xyloglucan specific | Aspergillus | Endo-processive | Xyloglucanases | Fungal glucanases | Microbiology | Microbial Genetics and Genomics | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Xylans - metabolism | Glycoside Hydrolases - genetics | Aspergillus fumigatus - enzymology | Catalytic Domain - genetics | Substrate Specificity | Ascomycota - enzymology | Phylogeny | Aspergillus fumigatus - genetics | Hydrolysis | Genome, Fungal | Glycosides - metabolism | Ascomycota - genetics | Glycoside Hydrolases - chemistry | Glucans - metabolism | Glycoside Hydrolases - metabolism | Enzymes | Genomics | Tryptophan | Glucose | Dextrose | Fungi | Studies | Analysis | Genomes | Biochemistry | Genetic diversity | Biomass | Catalysis | Index Medicus
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11. Full Text Mutations in hmg1, Challenging the Paradigm of Clinical Triazole Resistance in Aspergillus fumigatus
by Rybak, Jeffrey M and Ge, Wenbo and Wiederhold, Nathan P and Parker, Josie E and Kelly, Steven L and Rogers, P. David and Fortwendel, Jarrod R
mBio, ISSN 2150-7511, 03/2019, Volume 10, Issue 2, p. e00437-19
Life Sciences & Biomedicine | Microbiology | Science & Technology | Antifungal Agents - pharmacology | Aspergillus fumigatus - drug effects | Humans | Aspergillus fumigatus - enzymology | Mutant Proteins - genetics | Mutant Proteins - metabolism | Aspergillus fumigatus - genetics | Triazoles - pharmacology | Hydroxymethylglutaryl CoA Reductases - metabolism | Aspergillus fumigatus - isolation & purification | Aspergillosis - microbiology | Drug Resistance, Fungal | Hydroxymethylglutaryl CoA Reductases - genetics | Index Medicus | Aspergillus fumigatus | HMG-CoA reductase | antifungal resistance | ergosterol | hmg1 | triazole
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