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PLoS Genetics, ISSN 1553-7390, 04/2008, Volume 4, Issue 4, pp. e1000046 - e1000046
Journal Article
Emerging Infectious Diseases, ISSN 1080-6040, 2011, Volume 17, Issue 10, pp. 1846 - 1854
The prevalence and spread of azole resistance in clinical Aspergillus fumigatus isolates in the Netherlands are currently unknown. Therefore, we performed a... 
VORICONAZOLE | INFECTIOUS DISEASES | INVASIVE ASPERGILLOSIS | FUNGAL DISEASE | ITRACONAZOLE RESISTANCE | NERVOUS-SYSTEM ASPERGILLOSIS | IN-VITRO SUSCEPTIBILITY | TRIAZOLE RESISTANCE | AMPHOTERICIN-B | MUTATIONS | IMMUNOLOGY | CYP51A GENE | Aspergillus fumigatus - drug effects | Prevalence | Prospective Studies | Humans | Middle Aged | Netherlands - epidemiology | Child, Preschool | Infant | Male | Azoles - therapeutic use | Aspergillosis - epidemiology | Antifungal Agents - therapeutic use | Microbial Sensitivity Tests | Young Adult | Aspergillus fumigatus - isolation & purification | Aged, 80 and over | Adult | Female | Child | Aspergillosis - drug therapy | Antifungal Agents - pharmacology | Drug Resistance, Fungal - genetics | Aspergillus fumigatus - genetics | Azoles - pharmacology | Adolescent | Aspergillosis - microbiology | Aged | Medical research | Fungicides | Leukemia | Genes | Cystic fibrosis | Transplantation | Drug resistance | Medical screening | Risk factors | Hematopoietic stem cells | Diseases | Netherlands | Amphotericin B | Gene mutations | Heterocyclic compounds | Cardiac patients | Transplantation of organs, tissues, etc | Medicine, Experimental | Strategic planning (Business) | Isolation (Hospital care) | Antiparasitic agents | Health aspects | Public health | Itraconazole | Index Medicus | prevalence | antifungal drug resistance | Aspergillosis | CME | outcome assessment | Research | aspergillus | fungal infections | the Netherlands
Journal Article
Nature, ISSN 0028-0836, 12/2005, Volume 438, Issue 7071, pp. 1105 - 1115
Journal Article
Journal Article
by Mulligan, Stephanie and de Córdoba, Santiago Rodriguez and Bowyer, Paul and Rabbinowitsch, Ester and Mohamoud, Yasmin and Wortman, Jennifer R and Denning, David W and Bennett, Joan and Goldman, Gustavo H and Dyer, Paul S and Konzack, Sven and Huang, Jiaqi and Chen, Dan and Kobayashi, Tetsuo and May, Gregory S and Li, Weixi and Takeuchi, Michio and Pain, Arnab and Price, Claire and Coulsen, Richard and Horiuchi, H and Seeger, Kathy and Nierman, William C and Fraser, Claire and Sánchez-Ferrero, Juan C and Latgé, Jean-Paul and Kumagai, Toshitaka and Majoros, William H and Tekaia, Fredj and Griffith-Jones, Sam and Lord, Angela and Monod, Michel and Squares, Steven and Woodward, John and Fischer, Reinhard and Murphy, Lee and Lafton, Anne and Feldblyum, Tamara V and Rodríguez-Peña, Jose M and Abe, Keietsu and Farman, Mark and Pritchard, Bethan L and Jiménez, Javier and Reichard, Utz and Hall, Neil and Fedorova, Natalie and Sanchez, Miguel and García, Maria J and Berriman, Matthew and Machida, Masayuki and Bermejo, Clara and Asai, Kiyoshi and Gomi, Katsuya and Haas, Hubertus and Galagan, James E and Fraser, Audrey and Yu, Jae-Hyuk and Gwilliam, Ryan and Lu, Charles and Fosker, Nigel and O'Neil, Susan and Renauld, Hubert and Humphray, Sean and Rutter, Simon and de Aldana, Carlos R. Vazquez and Anderson, Michael J and White, Owen and Kim, H. Stanley and Paulsen, Ian and Peñalva, Miguel A and Haas, Brian and Mouyna, Isabelle and Salzberg, Steven L and Fedorova, Nadia and Goble, Arlette and Keller, Nancy and Harris, David and Davies, Robert and Quail, Michael A and Rawlins, Neil and Archer, David B and García, Jose L and Robson, Geoffrey D and Pertea, Mihaela and Turner, Geoffrey and Arroyo, Javier and Squares, Rob and Kitamoto, Katsuhiko and Kulkarni, Resham and Molina, Maria and Miller, Bruce L and Ronning, Catherine M and Rajandream, Marie-Adele and Collins, Matthew and Saunders, David and Weidman, Janice and Khouri, Hoda and Barrell, Bart
Nature, ISSN 0028-0836, 12/2005, Volume 438, Issue 7071, pp. 1151 - 1156
Journal Article
Molecular Microbiology, ISSN 0950-382X, 10/2008, Volume 70, Issue 1, pp. 27 - 43
Journal Article
Journal of Antimicrobial Chemotherapy, ISSN 0305-7453, 12/2016, Volume 71, Issue 12, pp. 3528 - 3535
Journal Article
Emerging Infectious Diseases, ISSN 1080-6040, 07/2009, Volume 15, Issue 7, pp. 1068 - 1076
Azoles are the mainstay of oral therapy for aspergillosis. Azole resistance in Aspergillus has been reported infrequently. The first resistant isolate in... 
SYSTEM | INFECTIOUS DISEASES | INVASIVE ASPERGILLOSIS | ITRACONAZOLE RESISTANCE | HIGH-RESOLUTION | CROSS-RESISTANCE | ANTIFUNGAL AGENTS | IN-VITRO SUSCEPTIBILITY | MECHANISMS | MUTATIONS | IMMUNOLOGY | CYP51A GENE | Aspergillus fumigatus - drug effects | Humans | Fungal Proteins - drug effects | Azoles - therapeutic use | Fungal Proteins - genetics | Pyrimidines - pharmacology | Aspergillus fumigatus - genetics | Disease Progression | Itraconazole - pharmacology | Antifungal Agents - therapeutic use | Itraconazole - therapeutic use | Triazoles - pharmacology | Cytochrome P-450 Enzyme System - drug effects | Pyrimidines - therapeutic use | Treatment Failure | Voriconazole | Cytochrome P-450 Enzyme System - genetics | Drug Resistance, Fungal | Amino Acid Substitution | Aspergillosis - drug therapy | Evolution, Molecular | Triazoles - therapeutic use | Lung diseases, Obstructive | Care and treatment | Methionine | Mycoses | Transplantation | Drug resistance | Hematopoietic stem cells | Endowments | Algorithms | Codon | Evolutionary biology | Amphotericin B | Gene mutations | Triazoles | Analysis | Antiparasitic agents | Cross infection | Nosocomial infections | Health aspects | Itraconazole | Index Medicus | Aspergillus | population genetics | antifungal drug resistance | sterol 14-alpha demethylase CYP51A | Aspergillus fumigatus | azoles
Journal Article
PLoS Pathogens, ISSN 1553-7366, 04/2007, Volume 3, Issue 4, pp. 508 - 517
Secondary metabolites, including toxins and melanins, have been implicated as virulence attributes in invasive aspergillosis. Although not definitively proved,... 
NONRIBOSOMAL PEPTIDE SYNTHETASE | SECONDARY METABOLISM | VIRULENCE FACTORS | CONIDIAL PIGMENT | IMMUNOSUPPRESSIVE FUNGAL METABOLITE | MICROBIOLOGY | GLIOTOXIN INDUCES APOPTOSIS | CLUSTER | HORIZONTAL GENE-TRANSFER | HUMAN PATHOGENIC FUNGI | SIDEROPHORE BIOSYNTHESIS | PARASITOLOGY | Gene Expression Regulation, Fungal | Multigene Family | Oligonucleotide Array Sequence Analysis | Genomics | RNA, Messenger - genetics | Siderophores - genetics | Gene Expression Profiling | Aspergillus fumigatus - genetics | RNA, Messenger - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Iron - metabolism | Peptide Synthases - genetics | Peptide Synthases - metabolism | RNA, Fungal - metabolism | Genetic Variation | Chromosomes, Fungal - genetics | Gene Deletion | Transcription, Genetic | RNA, Fungal - genetics | Genes, Fungal - genetics | Genetic aspects | Research | Genetic regulation | Plant metabolites | Aspergillosis | Index Medicus | Pathogenicity | Immunology | Microbiology | Fungal | Computational Biology | Gene Expression Regulation | Mycotoxin | Genetics and Genomics | Aspergillus Fumigatus | Secondary Metabolism | Statistical analysis | Disease | Ontology | Mortality | AIDS | Infections | Biosynthesis | Genomes | Fungi | Studies | Acquired immune deficiency syndrome | HIV | Metabolites | Human immunodeficiency virus
Journal Article