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European Journal of Clinical Pharmacology, ISSN 0031-6970, 11/2016, Volume 72, Issue 11, pp. 1353 - 1361
Journal Article
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 08/2013, Volume 62, Issue 6, pp. 505 - 512
Journal Article
American Journal of Cardiovascular Drugs, ISSN 1175-3277, 04/2010, Volume 10, Issue 2, pp. 95 - 103
Background The Polycap™ (polypill; aspirin [acetylsalicylic acid], ramipril, simvastatin, atenolol, and hydrochlorothiazide) was found to be safe and effective... 
Drug-interactions | Ramipril, pharmacokinetics | Aspirin, pharmacokinetics | Hydrochlorothiazide, pharmacokinetics | Hydrochlorothiazide/atenolol/ramipril/simvastatin/aspirin, pharmacokinetics | Salicylic-acid, pharmacokinetics | Atenolol, pharmacokinetics | Risk-factors | Hydrochlorothiazide/atenolol/ramipril/simvastatin/aspirin, drug interactions | Simvastatin, pharmacokinetics | Cardiovascular-disorders, treatment | Pharmacotherapy | Medicine & Public Health | Cardiology | Pharmacology/Toxicology | CYTOCHROME-P450 | CARDIAC & CARDIOVASCULAR SYSTEMS | LOW-DOSE ASPIRIN | PHARMACOKINETICS | METABOLISM | FORMULATIONS | SIMVASTATIN ACID | CARDIOVASCULAR-DISEASE | PHARMACOLOGY & PHARMACY | BIOEQUIVALENCE | Hydrochlorothiazide - pharmacokinetics | Simvastatin - adverse effects | Area Under Curve | Cardiovascular Diseases - prevention & control | Humans | Middle Aged | Antihypertensive Agents - administration & dosage | Aspirin - pharmacokinetics | Biological Availability | Male | Aspirin - administration & dosage | Ramipril - administration & dosage | Young Adult | Capsules | Drug Interactions | Aspirin - adverse effects | Atenolol - pharmacokinetics | Platelet Aggregation Inhibitors - administration & dosage | Adult | Platelet Aggregation Inhibitors - pharmacokinetics | Atenolol - administration & dosage | Ramipril - adverse effects | Tandem Mass Spectrometry - methods | Platelet Aggregation Inhibitors - adverse effects | Hydrochlorothiazide - adverse effects | Cardiovascular Diseases - etiology | Hypolipidemic Agents - adverse effects | Administration, Oral | Simvastatin - administration & dosage | Risk Factors | Ramipril - pharmacokinetics | Hydrochlorothiazide - administration & dosage | Antihypertensive Agents - pharmacokinetics | Simvastatin - pharmacokinetics | Antihypertensive Agents - adverse effects | Cross-Over Studies | Adolescent | Hypolipidemic Agents - administration & dosage | Atenolol - adverse effects | Chromatography, Liquid - methods | Hypolipidemic Agents - pharmacokinetics | Drug Combinations | Prevention | Complications and side effects | Drug interactions | Dosage and administration | Research | Cardiovascular diseases | Risk factors | Cardiovascular agents
Journal Article
Diabetes Research and Clinical Practice, ISSN 0168-8227, 2014, Volume 104, Issue 3, pp. 401 - 409
Journal Article
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 03/2012, Volume 83, Issue 6, pp. 715 - 722
Journal Article
Journal Article
Pediatric Anesthesia, ISSN 1155-5645, 12/2018, Volume 28, Issue 12, pp. 1087 - 1095
Journal Article
Thrombosis and Haemostasis, ISSN 0340-6245, 08/2004, Volume 92, Issue 2, pp. 311 - 316
Journal Article
Clinical Pharmacokinetics, ISSN 0312-5963, 12/2010, Volume 49, Issue 12, pp. 777 - 798
Thienopyridines are inactive prodrugs that are converted in vivo to active metabolites, which irreversibly bind to and inactivate platelet P2Y12 receptors, and... 
Pharmacotherapy | Internal Medicine | Medicine & Public Health | Pharmacology/Toxicology | Drug-interactions | Antiplatelets, pharmacokinetics | Antithrombotics, pharmacodynamics | Research-and-development | Prasugrel, pharmacodynamics | Metabolites | Pharmacokinetic-pharmacodynamic-relationships | Prasugrel, pharmacokinetics | Antiplatelets, pharmacodynamics | Antithrombotics, pharmacokinetics | PERCUTANEOUS CORONARY INTERVENTION | DRUG INTERACTIONS | MYOCARDIAL-INFARCTION | HUMAN PLATELET-AGGREGATION | ACTIVE METABOLITE FORMATION | PHARMACOLOGY & PHARMACY | ASPIRIN-TREATED PATIENTS | DOSE CLOPIDOGREL | CLOPIDOGREL 300 MG | THIENOPYRIDINE ANTIPLATELET AGENT | P-GLYCOPROTEIN | Purinergic P2Y Receptor Antagonists - pharmacology | Prasugrel Hydrochloride | Angioplasty, Balloon, Coronary - methods | Humans | Purinergic P2Y Receptor Antagonists - pharmacokinetics | Thiophenes - pharmacology | Piperazines - pharmacology | Thiophenes - pharmacokinetics | Acute Coronary Syndrome - complications | Drug Interactions | Platelet Aggregation Inhibitors - pharmacology | Acute Coronary Syndrome - therapy | Platelet Aggregation - drug effects | Platelet Aggregation Inhibitors - pharmacokinetics | Piperazines - pharmacokinetics | Prevention | Cytochrome P-450 | Physiological aspects | Research | Drug therapy | Pharmacokinetics | Coronary heart disease
Journal Article