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Journal of Clinical Oncology, ISSN 0732-183X, 09/2017, Volume 35, Issue 25, pp. 2934 - 2941
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 05/1999, Volume 5, Issue 5, pp. 1107 - 1113
Journal Article
Journal Article
Acta Neuropathologica, ISSN 0001-6322, 4/2017, Volume 133, Issue 4, pp. 629 - 644
Mutations in codon 132 of isocitrate dehydrogenase (IDH) 1 are frequent in diffuse glioma, acute myeloid leukemia, chondrosarcoma and intrahepatic... 
Pathology | Therapy | Neurosciences | IDH-mutated glioma | Medicine & Public Health | IDH1R132 inhibitor | Pharmacology | Drug development | Mouse xenograft | SELECTIVE-INHIBITION | GLIOMAS | ISOCITRATE DEHYDROGENASE | PHENOTYPE | ACUTE MYELOID-LEUKEMIA | PATHOLOGY | NEUROSCIENCES | CLINICAL NEUROLOGY | BRAIN-TUMORS | GLIOBLASTOMAS | TUMOR STEM-CELLS | MUTATIONS | DIFFERENTIATION | Benzimidazoles - toxicity | Colonic Neoplasms - genetics | Colonic Neoplasms - drug therapy | Escherichia coli | Humans | Sarcoma - enzymology | Benzimidazoles - chemistry | Isocitrate Dehydrogenase - antagonists & inhibitors | Antineoplastic Agents - toxicity | Sf9 Cells | Enzyme Inhibitors - pharmacokinetics | Enzyme Inhibitors - chemistry | Enzyme Inhibitors - toxicity | Astrocytoma - drug therapy | HEK293 Cells | Astrocytoma - enzymology | Female | Antineoplastic Agents - pharmacokinetics | Antineoplastic Agents - pharmacology | Sarcoma - genetics | Cell Survival - physiology | Astrocytoma - genetics | Recombinant Proteins - metabolism | Cell Survival - drug effects | Brain Neoplasms - enzymology | Aniline Compounds - pharmacology | Enzyme Inhibitors - pharmacology | Benzimidazoles - pharmacokinetics | Brain Neoplasms - genetics | Isocitrate Dehydrogenase - genetics | Recombinant Proteins - genetics | Aniline Compounds - pharmacokinetics | Aniline Compounds - toxicity | Antineoplastic Agents - chemistry | Brain Neoplasms - drug therapy | Sarcoma - drug therapy | Xenograft Model Antitumor Assays | Animals | Mice, Nude | Cell Line, Tumor | Benzimidazoles - pharmacology | Isocitrate Dehydrogenase - metabolism | Colonic Neoplasms - enzymology | Glutarates - metabolism | Mice, Inbred BALB C | Aniline Compounds - chemistry | Mutation | Gliomas | Genetic aspects | Codon | Index Medicus
Journal Article
Journal Article
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2017, Volume 12, Issue 2, pp. e0172234 - e0172234
Astrocytomas are the most frequent primary brain tumors in adults, and despite aggressive treatment patients often experience recurrence. Survival decreases... 
ISOCITRATE DEHYDROGENASE 1 | NERVOUS-SYSTEM | GELATINASE-A | STEM-CELL MARKERS | IMMUNOREACTIVE PROTEIN | MULTIDISCIPLINARY SCIENCES | PHASE-3 TRIAL | MALIGNANT GLIOMAS | GROWTH-FACTOR | MESENCHYMAL DIFFERENTIATION | HIGH-GRADE GLIOMA | Immunohistochemistry | Glioblastoma - enzymology | Prognosis | Humans | Middle Aged | Brain Neoplasms - pathology | Gene Expression Regulation, Neoplastic | Extracellular Matrix - metabolism | Male | Young Adult | Tissue Inhibitor of Metalloproteinase-1 - metabolism | Astrocytoma - pathology | Adult | Astrocytoma - enzymology | Female | Astrocytoma - diagnosis | Brain Neoplasms - enzymology | Glioblastoma - diagnosis | Matrix Metalloproteinase 2 - metabolism | Brain Neoplasms - diagnosis | Computational Biology | Neoplasm Recurrence, Local | Treatment Outcome | Extracellular Matrix - enzymology | Gene Expression Regulation, Enzymologic | Image Processing, Computer-Assisted | Glioblastoma - pathology | Cell Line, Tumor | Isocitrate Dehydrogenase - metabolism | Aged | Software | Care and treatment | Proteases | Development and progression | Genetic aspects | Gene expression | Health aspects | Astrocytoma | Brain | Random sampling | Brain tumors | Brain cancer | Glioblastoma | Oncology | Matrix metalloproteinase | Kinases | Tissue inhibitor of metalloproteinase 1 | Cancer therapies | Angiogenesis | Extracellular matrix | Metalloproteinase | Bioinformatics | Growth factors | Medical research | Tumor cells | Blood vessels | Patients | Survival | Gelatinase A | Studies | Pathology | Survival analysis | Brain research | Hospitals | Medical prognosis | Biomarkers | Adults | Statistical sampling | Cytoplasm | Tumors | Index Medicus
Journal Article
Journal Article
Journal Article
The American Journal of Surgical Pathology, ISSN 0147-5185, 07/2017, Volume 41, Issue 11, pp. 1456 - 1465
Myxoinflammatory fibroblastic sarcoma (MIFS) is a low grade soft tissue sarcoma with a predilection for acral sites, being associated with a high rate of local... 
BRAF | amplifications | MAPK | myxoinflammatory fibroblastic sarcoma | fusions | VGLL3 | TRANSCRIPTION FACTORS | TARGETED THERAPY | SURGERY | MAPK PATHWAY ACTIVATION | PROTEIN | HYBRIDIZATION | PATHOLOGY | CANCER | KINASE FUSION | MGEA5 REARRANGEMENTS | PILOCYTIC ASTROCYTOMAS | RAF | BRAF fusions | Immunohistochemistry | Phosphorylation | Receptors, Transforming Growth Factor beta - genetics | Humans | Middle Aged | Lipoma - genetics | Histone Acetyltransferases - genetics | Male | Lipoma - pathology | Hemosiderosis - pathology | Case-Control Studies | Fibrosarcoma - pathology | Neoplasm Grading | Hemosiderosis - genetics | Adult | Female | Soft Tissue Neoplasms - enzymology | Soft Tissue Neoplasms - genetics | Antigens, Neoplasm - genetics | Genetic Predisposition to Disease | Biomarkers, Tumor - analysis | RNA, Messenger - genetics | Hemosiderosis - enzymology | Gene Fusion | In Situ Hybridization, Fluorescence | Transcription Factors - genetics | Reverse Transcriptase Polymerase Chain Reaction | Extracellular Signal-Regulated MAP Kinases - analysis | Carrier Proteins - genetics | Lipoma - enzymology | Fibrosarcoma - genetics | Phenotype | Gene Amplification | Sequence Analysis, RNA | Proto-Oncogene Proteins B-raf - genetics | Gene Rearrangement | Soft Tissue Neoplasms - pathology | Aged | Biomarkers, Tumor - genetics | Fibrosarcoma - enzymology | Hyaluronoglucosaminidase - genetics | Proteoglycans - genetics | Index Medicus | Myxoinflammatory fibroblastic sarcoma
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 11/2015, Volume 14, Issue 11, pp. 2560 - 2568
Journal Article