X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (557) 557
Publication (101) 101
Book Review (8) 8
Book Chapter (7) 7
Conference Proceeding (1) 1
Magazine Article (1) 1
Trade Publication Article (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
ataxin-1 (478) 478
ataxins (395) 395
humans (365) 365
animals (346) 346
nerve tissue proteins - genetics (291) 291
nuclear proteins - genetics (290) 290
mice (260) 260
index medicus (255) 255
nuclear proteins - metabolism (190) 190
nerve tissue proteins - metabolism (188) 188
spinocerebellar ataxias - genetics (145) 145
female (133) 133
male (132) 132
neurosciences (128) 128
biochemistry & molecular biology (127) 127
spinocerebellar ataxia (120) 120
cell biology (107) 107
genetics & heredity (100) 100
neurodegeneration (89) 89
sca1 (88) 88
mice, transgenic (86) 86
proteins (82) 82
disease models, animal (79) 79
mutation (79) 79
spinocerebellar ataxias - pathology (75) 75
mice, inbred c57bl (71) 71
protein (71) 71
expression (70) 70
article (69) 69
disease (69) 69
expansion (65) 65
phenotype (65) 65
adult (61) 61
peptides - genetics (61) 61
transgenic mice (61) 61
ataxia (60) 60
aggregation (59) 59
spinocerebellar ataxias - metabolism (59) 59
gene expression (58) 58
cag repeat (57) 57
huntingtons-disease (56) 56
middle aged (54) 54
nuclear proteins - chemistry (54) 54
nerve tissue proteins - chemistry (53) 53
peptides - metabolism (53) 53
research (53) 53
analysis (52) 52
ataxin-1 - metabolism (52) 52
nervous system diseases (52) 52
polyglutamine (52) 52
trinucleotide repeat (51) 51
trinucleotide repeats (51) 51
molecular sequence data (50) 50
sca1 transgenic mice (50) 50
cells, cultured (49) 49
stem cells (49) 49
gene (46) 46
spinocerebellar ataxia type-1 (46) 46
ataxin-1 - genetics (45) 45
ataxin-3 (44) 44
neurology (44) 44
spinocerebellar ataxias - physiopathology (44) 44
multidisciplinary sciences (43) 43
phosphorylation (43) 43
purkinje cells - metabolism (41) 41
trinucleotide repeat expansion - genetics (41) 41
amino acid sequence (40) 40
clinical neurology (40) 40
identification (40) 40
neurons (40) 40
cerebellum (39) 39
protein binding (39) 39
cell differentiation (38) 38
cerebellum - pathology (38) 38
rodents (38) 38
cell line (37) 37
purkinje cells - pathology (37) 37
ataxin (36) 36
differentiation (36) 36
genetic aspects (36) 36
spinocerebellar degenerations - genetics (36) 36
huntingtin protein (35) 35
progenitor cells (34) 34
spinocerebellar ataxia type 1 (34) 34
brain (33) 33
cell nucleus - metabolism (33) 33
hela cells (33) 33
research article (33) 33
alleles (32) 32
immunohistochemistry (32) 32
pathogenesis (32) 32
type-1 (32) 32
gene expression regulation (31) 31
genetics (31) 31
nuclear proteins - physiology (31) 31
physiological aspects (31) 31
transfection (31) 31
cerebellum - metabolism (30) 30
nerve tissue proteins - physiology (30) 30
aged (29) 29
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Human Molecular Genetics, ISSN 0964-6906, 10/2001, Volume 10, Issue 20, pp. 2307 - 2311
Spinocerebellar ataxia type 1 (SCA1) is a relatively rare autosomal-dominant neurological disorder. SCA1 has the intriguing feature that the disease-causing... 
ataxin-1
Journal Article
Journal Article
Glia, ISSN 0894-1491, 09/2018, Volume 66, Issue 9, pp. 1972 - 1987
Spinocerebellar ataxia type 1 (SCA1) is a fatal, dominantly inherited neurodegenerative disease caused by the expansion of CAG repeats in the Ataxin‐1 (ATXN1)... 
neurodestructive | astroglia | ATAXIN‐1 | neuroprotective | nuclear factor kappa b | neurodegeneration | cerebellum | ATAXIN-1 | NEURODEGENERATIVE DISEASE | EXPRESSION ANALYSIS | ALZHEIMERS-DISEASE | AMYOTROPHIC-LATERAL-SCLEROSIS | NEUROSCIENCES | CENTRAL-NERVOUS-SYSTEM | BERGMANN GLIAL-CELLS | NF-KAPPA-B | HUNTINGTONS-DISEASE | TRANSGENIC MICE | TRINUCLEOTIDE REPEAT | Motor Activity - physiology | Neurons - pathology | Astrocytes - pathology | Male | NF-kappa B - metabolism | Gliosis - physiopathology | Glial Fibrillary Acidic Protein - metabolism | Gliosis - pathology | Microglia - physiology | I-kappa B Kinase - metabolism | Ataxin-1 - metabolism | Neurons - physiology | Microglia - pathology | Female | Ataxin-1 - genetics | Disease Models, Animal | Mice, Inbred C57BL | Neuroprotection - physiology | Mice, Transgenic | Spinocerebellar Ataxias - physiopathology | Cerebellum - physiopathology | I-kappa B Kinase - genetics | Random Allocation | Spinocerebellar Ataxias - pathology | Disease Progression | Cerebellum - pathology | Astrocytes - physiology | Animals | Animal genetics | Development and progression | Ataxia | Nervous system diseases | B cells | Cerebellum | Neuroprotection | Polyglutamine | Coordination | Neurons | Astrocytes | Pathogenesis | Trinucleotide repeats | Motors | Inflammation | Signaling | Gliosis | Ataxin | Lymphocytes B | Purkinje cells | Spinocerebellar ataxia | Liquid oxygen | Inhibition
Journal Article
Journal Article
Nature Genetics, ISSN 1061-4036, 03/2017, Volume 49, Issue 4, pp. 527 - 536
Journal Article
Journal of Neuroinflammation, ISSN 1742-2094, 05/2017, Volume 14, Issue 1, pp. 107 - 11
Background: Polyglutamine (polyQ) expansion in the protein Ataxin-1 (ATXN1) causes spinocerebellar ataxia type 1 (SCA1), a fatal dominantly inherited... 
Cerebellum | Motor deficit | SCA1 | Spinocerebellar Ataxia type 1 | Neuroinflammation | Glia | ATAXIN-1 | Microglia | Purkinje neurons | SPINOCEREBELLAR ATAXIA TYPE-1 | CELLS | CONTRIBUTE | MICROGLIAL ACTIVATION | IMPAIRS | IMMUNOLOGY | NEUROSCIENCES | MOUSE MODEL | EXPRESSION | NEURONAL DYSFUNCTION | PROGRESSION | TRANSGENIC MICE | Tumor Necrosis Factor-alpha - metabolism | Disks Large Homolog 4 Protein - metabolism | Motor Activity - drug effects | Postural Balance - drug effects | Glial Fibrillary Acidic Protein - metabolism | Neuroglia - drug effects | Aminopyridines - therapeutic use | Ataxin-1 - metabolism | Microfilament Proteins - metabolism | Pyrroles - therapeutic use | Ataxin-1 - genetics | Spinocerebellar Ataxias - genetics | Calcium-Binding Proteins - metabolism | Spinocerebellar Ataxias - complications | Gene Expression Regulation - genetics | Macrophage Colony-Stimulating Factor - antagonists & inhibitors | Mice, Inbred C57BL | Vesicular Glutamate Transport Protein 2 - metabolism | Mice, Transgenic | Macrophage Colony-Stimulating Factor - metabolism | Postural Balance - genetics | Mutation - genetics | Motor Disorders - therapy | Cerebellum - pathology | Gene Expression Regulation - drug effects | Motor Activity - genetics | Animals | Motor Disorders - etiology | Neuroglia - metabolism | Mice | Traumatic brain injury | Disease | Pathogenesis | Weaning | Synaptic density | Motor task performance | Experiments | Atrophy | Ataxin | Neurodegeneration | Purkinje cells | Rodents | Spinocerebellar ataxia | Ataxia | Colony-stimulating factor | Trinucleotide repeat diseases | Age | Polyglutamine | Neurons | Transgenic mice | Macrophage colony-stimulating factor | Amyotrophic lateral sclerosis | Inflammation | Gene expression | Studies | Pathology | Gliosis | Tumor necrosis factor | Internet | Postsynaptic density proteins | Laboratory animals
Journal Article