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Autophagy, ISSN 1554-8627, 2014, Volume 10, Issue 8, p. 1481
Journal Article
Autophagy, ISSN 1554-8627, 08/2014, Volume 10, Issue 8, pp. 1481 - 1481
Journal Article
Molecular cell, ISSN 1097-2765, 2015, Volume 59, Issue 2, pp. 285 - 297
Many tumors become addicted to autophagy for survival, suggesting inhibition of autophagy as a potential broadly applicable cancer therapy. ULK1/Atg1 is the... 
MAMMALIAN TARGET | COMPLEX | POTENT | PROTEIN | ATG101 | BIOCHEMISTRY & MOLECULAR BIOLOGY | AMPK | BINDING | TUMORS | MTOR | DIRECT PHOSPHORYLATION | CELL BIOLOGY | Consensus Sequence | Protein-Serine-Threonine Kinases - deficiency | RNA, Small Interfering - genetics | Phosphorylation | Humans | Molecular Sequence Data | Substrate Specificity | Autophagy - physiology | Intracellular Signaling Peptides and Proteins - metabolism | Autophagy - drug effects | Pyrimidines - chemistry | Autophagy-Related Protein-1 Homolog | Protein Kinase Inhibitors - chemistry | HEK293 Cells | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Benzamides - pharmacology | Intracellular Signaling Peptides and Proteins - genetics | Cell Survival - physiology | Protein-Serine-Threonine Kinases - metabolism | Benzamides - chemistry | Recombinant Proteins - metabolism | Amino Acid Sequence | Cell Survival - drug effects | Intracellular Signaling Peptides and Proteins - antagonists & inhibitors | Catalytic Domain - genetics | Cells, Cultured | Protein-Serine-Threonine Kinases - genetics | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | Pyrimidines - pharmacology | Gene Knockout Techniques | Animals | Mice | Protein Kinase Inhibitors - pharmacology | Proteins | Medical colleges | Medical research | Cell death | Medicine, Experimental | Cellular signal transduction | Research institutes | Cells
Journal Article
Circulation Research, ISSN 0009-7330, 04/2011, Volume 108, Issue 7, pp. 787 - 788
Journal Article
Autophagy, ISSN 1554-8635, 2018, Volume 14, Issue 5, pp. 743 - 763
Macroautophagy/autophagy is an evolutionarily conserved cellular process whose induction is regulated by the ULK1 protein kinase complex. The subunit ATG13... 
ULK1 | autophagy | ATG101 | ATG13 | RB1CC1 | CELLS | COMPLEX | REGULATES ATG9 | RECRUITS ATG9 | INITIATING KINASE ULK1 | MTOR | CELL BIOLOGY | STRUCTURAL BASIS | PROTEIN ATG8 | HORMA DOMAIN | BINDING
Journal Article
The Journal of cell biology, ISSN 1540-8140, 2018, Volume 217, Issue 11, pp. 3817 - 3828
Macroautophagy is an intracellular degradation process that requires multiple autophagy-related (ATG) genes. In this study, we performed a genome-wide screen... 
TOPOLOGY | CELLS | MUTANTS | PROTEIN | EVOLUTION | FUSION | TRANSPORTERS | ATG101 | SELECTIVE AUTOPHAGY | PEXOPHAGY | CELL BIOLOGY | Genome-Wide Association Study | Endoplasmic Reticulum - genetics | Membrane Proteins - genetics | Gene Deletion | Humans | CRISPR-Cas Systems | HEK293 Cells | Endoplasmic Reticulum - metabolism | Membrane Proteins - metabolism | Autophagosomes - metabolism
Journal Article
Autophagy, ISSN 1554-8627, 11/2015, Volume 11, Issue 11, pp. 2123 - 2124
The Atg1/ULK complex functions as the most upstream factor among Atg proteins to initiate autophagy. ATG101 is a constitutive component of the Atg1/ULK complex... 
crystal structure | ULK complex | Atg101 | autophagy initiation | HORMA | Atg13 | Autophagy initiation | Crystal structure | CELL BIOLOGY
Journal Article
Journal Article
Journal Article
Cell structure and function, ISSN 0386-7196, 2016, Volume 41, Issue 1, pp. 13 - 20
The Saccharomyces cerevisiae autophagy-initiation complex, Atg1 kinase complex, consists of Atg1, Atg13, Atg17, Atg29, and Atg31, while the corresponding... 
Atg101 | HORMA | Atg13 | Autophagy | MAD2 | PROTEIN | KINASE | HOMOLOG | CELL BIOLOGY | YEAST | INTERACTS | PICHIA-PASTORIS | HORMA DOMAIN | ULK1 | Protein Kinases - metabolism | Animals | Humans | Protein Kinases - chemistry | Protein Subunits - chemistry | Yeasts - enzymology | Protein Subunits - metabolism
Journal Article