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Journal of Neuroscience, ISSN 0270-6474, 10/2012, Volume 32, Issue 43, pp. 15148 - 15157
Several behavioral effects of nicotine are mediated by changes in serotonin (5-HT) release in brain areas that receive serotonergic afferents from the dorsal... 
Electric Stimulation | Rats, Wistar | Dihydro-beta-Erythroidine - pharmacology | Male | Nicotinic Antagonists - pharmacology | Raphe Nuclei - cytology | Excitatory Postsynaptic Potentials - drug effects | Nicotine - pharmacology | Excitatory Postsynaptic Potentials - physiology | Muscarinic Antagonists - pharmacology | Egtazic Acid - analogs & derivatives | 6-Cyano-7-nitroquinoxaline-2,3-dione - pharmacology | Indoles - pharmacology | Tetrodotoxin - pharmacology | Cadmium Chloride - pharmacology | Cholinergic Agonists - pharmacology | Ryanodine - pharmacology | Animals, Newborn | Serotonergic Neurons - physiology | Presynaptic Terminals - drug effects | Acetylcholine - pharmacology | Enzyme Inhibitors - pharmacology | Glutamic Acid - physiology | Rats | Atropine - pharmacology | Sodium Channel Blockers - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Presynaptic Terminals - physiology | Aconitine - analogs & derivatives | Bicuculline - pharmacology | Chelating Agents - pharmacology | Aconitine - pharmacology | GABA Antagonists - pharmacology | Physostigmine - pharmacology | Patch-Clamp Techniques | Animals | Egtazic Acid - pharmacology | Receptors, Nicotinic - physiology | Nicotine - analogs & derivatives | Serotonin - metabolism | In Vitro Techniques | Serotonergic Neurons - cytology | Index Medicus
Journal Article
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 01/1997, Volume 17, Issue 2, pp. 576 - 585
Presynaptic nicotinic acetylcholine receptors (nAChRs) are present in many regions of the brain and potentially serve as targets for the pharmacological action... 
GABA | calcium | facilitation | thalamus (sensory nuclei) | nicotinic acetylcholine receptors | presynaptic | ADRENAL CHROMAFFIN CELLS | INTERPEDUNCULAR NUCLEUS | FROG NEUROMUSCULAR-JUNCTION | OPTIC-NERVE TERMINALS | RAT CENTRAL NEURONS | NEUROSCIENCES | LATERAL GENICULATE-NUCLEUS | ACETYLCHOLINE-RECEPTORS | SUBUNIT MESSENGER-RNAS | CHOLINERGIC RECEPTORS | EXCITATORY SYNAPTIC TRANSMISSION | Thalamic Nuclei - metabolism | Dihydro-beta-Erythroidine - pharmacology | Lobeline - pharmacology | Nicotinic Antagonists - pharmacology | Pyridazines - pharmacology | Cations, Divalent - pharmacology | Nicotine - pharmacology | Quinolizines | Calcium Channels - physiology | Calcium - physiology | Receptors, Nicotinic - chemistry | Receptors, GABA-A - drug effects | 6-Cyano-7-nitroquinoxaline-2,3-dione - pharmacology | Receptors, Nicotinic - deficiency | Dimethylphenylpiperazinium Iodide - pharmacology | Ion Transport | gamma-Aminobutyric Acid - secretion | Tetrodotoxin - pharmacology | Action Potentials - drug effects | Nicotinic Agonists - pharmacology | Microcystins | Alkaloids - pharmacology | Mice, Inbred C57BL | Atropine - pharmacology | Aconitine - analogs & derivatives | Marine Toxins - pharmacology | Aconitine - pharmacology | Calcium Channel Blockers - pharmacology | Potassium - pharmacology | Neurons, Afferent - physiology | GABA Antagonists - pharmacology | Mice, Knockout | Carbachol - pharmacology | Arousal - physiology | Bridged Bicyclo Compounds, Heterocyclic - pharmacology | Patch-Clamp Techniques | Animals | Azocines | Receptors, Nicotinic - physiology | Bacterial Toxins - pharmacology | Thalamic Nuclei - secretion | Mice | Pyridines - pharmacology | Receptors, Nicotinic - genetics | Index Medicus
Journal Article
Journal Article
Pharmacology, Biochemistry and Behavior, ISSN 0091-3057, 03/2013, Volume 104, Issue 1, pp. 144 - 153
Journal Article
Clinical and Experimental Pharmacology and Physiology, ISSN 0305-1870, 01/2006, Volume 33, Issue 1, pp. 27 - 32
SUMMARY • The aim of the present study was to clarify the role of ginsenoside Rh2 as the active compound in Panax ginseng root for lowering plasma glucose in... 
Wistar rats | ginsenosides Rh2 | acetylcholine | insulin | muscarinic M3 receptors | 3 | receptors | muscarinic M | Muscarinic M | Acetylcholine | Ginsenosides Rh2 | Insulin | CELLS | PHYSIOLOGY | STIMULATION | PANAX-GINSENG | PERFORMANCE | RELEASE | MUSCARINIC ACETYLCHOLINE-RECEPTOR | INTESTINAL BACTERIA | PHARMACOKINETICS | HYPOGLYCEMIC ACTIVITY | PHARMACOLOGY & PHARMACY | MICE | muscarinic M-3 receptors | Injections, Intravenous | C-Peptide - blood | Enzyme-Linked Immunosorbent Assay | Rats, Wistar | Cholinergic Agents - pharmacology | Drugs, Chinese Herbal - pharmacology | Rats | Atropine - pharmacology | Male | Ginsenosides - pharmacology | Insulin - blood | Dose-Response Relationship, Drug | Insulin - metabolism | Animals | Piperidines - pharmacology | Hemicholinium 3 - pharmacology | Muscarinic Antagonists - pharmacology | Ginsenosides - administration & dosage | Blood Glucose - metabolism | Insulin Secretion | Neuromuscular Depolarizing Agents - pharmacology | Ginsenosides, administration and dosage | Atropine, pharmacology | Insulin, secretion | Insulin, blood | C-Peptide, blood | Blood Glucose, metabolism | Hemicholinium 3, pharmacology | Piperidines, pharmacology | Cholinergic Agents, pharmacology | Drugs, Chinese Herbal, pharmacology | Muscarinic Antagonists, pharmacology | Neuromuscular Depolarizing Agents, pharmacology | Ginsenosides, pharmacology | Index Medicus
Journal Article
Journal Article
Neuropsychopharmacology, ISSN 0893-133X, 04/2011, Volume 36, Issue 5, pp. 1021 - 1032
Nicotine activation of nicotinic acetylcholine receptors (nAChRs) within the dopaminergic (DAergic) neuron-rich ventral tegmental area (VTA) is necessary and... 
nicotine | acetylcholine | ventral tegmental area | dopamine | mice | smoking | PSYCHIATRY | REWARD | NEUROSCIENCES | NUCLEUS-ACCUMBENS | POSTERIOR | ACETYLCHOLINE-RECEPTORS | CIGARETTE-SMOKING | MUTANT MICE | SYNAPTIC MECHANISMS | ETHANOL | PHARMACOLOGY & PHARMACY | ALPHA-CONOTOXIN-MII | MIDBRAIN | Tyrosine 3-Monooxygenase - metabolism | Temperature | Male | Nicotinic Antagonists - pharmacology | Ventral Tegmental Area - cytology | RNA, Messenger - metabolism | Patch-Clamp Techniques - methods | Nicotine - pharmacology | Drug Interactions | Muscarinic Antagonists - pharmacology | Mecamylamine - pharmacology | 6-Cyano-7-nitroquinoxaline-2,3-dione - pharmacology | Receptors, Nicotinic - deficiency | Neurons - metabolism | Neurons - drug effects | Electric Stimulation - methods | Action Potentials - drug effects | Dopamine - metabolism | Nicotinic Agonists - pharmacology | GABA-A Receptor Antagonists - pharmacology | Receptors, Nicotinic - metabolism | Gene Expression Regulation - genetics | Cell Size - drug effects | Mice, Inbred C57BL | Proto-Oncogene Proteins c-fos - metabolism | Atropine - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Bicuculline - pharmacology | Mice, Knockout | Gene Expression Regulation - drug effects | Microdissection - methods | Animals | Cell Count - methods | Analysis of Variance | Mice | In Vitro Techniques | Receptors, Nicotinic - genetics | Index Medicus | addiction & substance abuse | neurophysiology | Original
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 09/2016, Volume 311, Issue 3, pp. H676 - H688
The cardiac pacemaker sets the heart's primary rate, with pacemaker discharge controlled by the autonomic nervous system through intra-cardiac ganglia. A... 
Intracardiac nervous system | Parasympathetic | Atrioventricular node | Sinoatrial node | Sympathetic | DANIO-RERIO | NERVOUS-SYSTEM | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | intracardiac nervous system | CONDUCTION SYSTEM | sympathetic | MUSCARINIC RECEPTORS | POSTGANGLIONIC NEURONS | sinoatrial node | ADULT ZEBRAFISH | ADRENERGIC-RECEPTORS | NUCLEUS AMBIGUUS | parasympathetic | VAGAL PREGANGLIONIC NEURONS | atrioventricular node | PERIPHERAL VASCULAR DISEASE | Muscarinic Agonists - pharmacology | Sympathetic Nervous System - drug effects | Heart - physiology | Sympathomimetics - pharmacology | Nicotinic Antagonists - pharmacology | Sinoatrial Node - drug effects | Atrioventricular Node - physiology | Atrioventricular Node - drug effects | Nicotine - pharmacology | Vagus Nerve Stimulation | Adrenergic beta-Antagonists - pharmacology | Hexamethonium - pharmacology | Sympathetic Nervous System - physiology | Muscarinic Antagonists - pharmacology | Electrocardiography | Models, Animal | Parasympathetic Nervous System - physiology | Nicotinic Agonists - pharmacology | Heart - innervation | Heart - physiopathology | Heart Rate | Receptor, Muscarinic M2 - metabolism | Autonomic Nervous System - drug effects | Isolated Heart Preparation | Sinoatrial Node - physiology | Autonomic Nervous System - physiology | Sinoatrial Node - physiopathology | Bradycardia - physiopathology | Atropine - pharmacology | Timolol - pharmacology | Zebrafish | Atrioventricular Node - innervation | Sinoatrial Node - innervation | Tachycardia - physiopathology | Receptors, Adrenergic, beta-2 - metabolism | Animals | Isoproterenol - pharmacology | Parasympathetic Nervous System - drug effects | Heart - drug effects | Muscarine - pharmacology | Atrioventricular Node - physiopathology | Health aspects | Pacemaker, Artificial (Heart) | Heart beat | Heart rate | Nervous system | Neurons | Cells | Index Medicus | Integrative Cardiovascular Physiology and Pathophysiology
Journal Article
European Journal of Neuroscience, ISSN 0953-816X, 09/2003, Volume 18, Issue 5, pp. 1155 - 1168
Tonic impulse flow in the septohippocampal GABAergic pathway is essential for normal cognitive functioning and is sustained, in part, by acetylcholine (ACh)... 
Learning and memory | Septum | Metabotropic | Cognition | Theta rhythm | Glutamate | DIAGONAL BAND COMPLEX | PARVALBUMIN | CA1 INTERNEURONS | cognition | ALZHEIMERS-DISEASE | IMPULSE FLOW | metabotropic | NEUROSCIENCES | septum | theta rhythm | ACETYLCHOLINE-RECEPTORS | learning and memory | MEDIAL SEPTAL AREA | CENTRAL-NERVOUS-SYSTEM | BASAL FOREBRAIN | RAT HIPPOCAMPUS | glutamate | Muscarinic Agonists - pharmacology | gamma-Aminobutyric Acid - metabolism | Cell Count | Septum of Brain - physiology | Parvalbumins - metabolism | Male | Nicotinic Antagonists - pharmacology | Drug Interactions | Neuroprotective Agents - pharmacology | Septum of Brain - ultrastructure | Vesicular Glutamate Transport Protein 2 | Muscarinic Antagonists - pharmacology | Hippocampus - ultrastructure | Tetrodotoxin - pharmacology | Chromones - pharmacology | Animals, Newborn | Membrane Potentials - drug effects | Drug Administration Routes | Acyclovir - pharmacology | Rats | Atropine - pharmacology | Synapses - ultrastructure | Excitatory Amino Acid Antagonists - pharmacology | Bicuculline - pharmacology | Rats, Sprague-Dawley | GABA Antagonists - pharmacology | Immunohistochemistry - methods | Glycine - pharmacology | Microscopy, Electron - methods | Muscarine - pharmacology | Glycine - analogs & derivatives | Electric Conductivity | Excitatory Postsynaptic Potentials - drug effects | Patch-Clamp Techniques - methods | Nicotine - pharmacology | Dose-Response Relationship, Drug | Resorcinols - pharmacology | Cycloleucine - pharmacology | Tubocurarine - pharmacology | Synapses - metabolism | Neurons - physiology | 6-Cyano-7-nitroquinoxaline-2,3-dione - pharmacology | Neurons - drug effects | Nicotinic Agonists - pharmacology | Vesicular Transport Proteins | Acyclovir - analogs & derivatives | Valine - analogs & derivatives | Aconitine - analogs & derivatives | Aconitine - pharmacology | Hippocampus - cytology | Membrane Potentials - physiology | Animals | Carrier Proteins - metabolism | Membrane Transport Proteins | Choline - pharmacology | Microscopy, Electron - instrumentation | Valine - pharmacology | In Vitro Techniques | Cycloleucine - analogs & derivatives | Bungarotoxins - pharmacology | Index Medicus
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 03/2005, Volume 25, Issue 9, pp. 2192 - 2203
The synaptic control of the astrocytic intracellular Ca (2+) is crucial in the reciprocal astrocyte - neuron communication. Using electrophysiological and Ca... 
Neurotransmitter release | Neuron-glia interaction | Intracellular calcium | Glutamate | Astrocytes | Synaptic activity | NEURONAL-ACTIVITY | ACTIVATION | synaptic activity | GLIAL-CELLS | neurotransmitter release | NEUROSCIENCES | DEPENDENT GLUTAMATE RELEASE | POTENTIATION | intracellular calcium | astrocytes | neuron-glia interaction | OSCILLATIONS | glutamate | IN-SITU | MODULATION | COMMUNICATION | Glycine - analogs & derivatives | Excitatory Postsynaptic Potentials - radiation effects | Synaptic Transmission - physiology | Rats, Wistar | Aniline Compounds - metabolism | Calcium - metabolism | Calcium Signaling - physiology | Cell Communication - physiology | Neurons - cytology | Glial Fibrillary Acidic Protein - metabolism | Excitatory Postsynaptic Potentials - drug effects | Patch-Clamp Techniques - methods | Diagnostic Imaging - methods | Excitatory Postsynaptic Potentials - physiology | Drug Interactions | Xanthenes - metabolism | Muscarinic Antagonists - pharmacology | Neurons - physiology | 6-Cyano-7-nitroquinoxaline-2,3-dione - pharmacology | Synaptic Transmission - drug effects | Tetrodotoxin - pharmacology | Electric Stimulation - methods | 4-Aminopyridine - pharmacology | Potassium Channel Blockers - pharmacology | Animals, Newborn | Astrocytes - cytology | Synapses - drug effects | Glutamic Acid - pharmacology | Acetylcholine - pharmacology | Synapses - physiology | Rats | Atropine - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Hippocampus - cytology | Immunohistochemistry - methods | Astrocytes - physiology | Animals | Glycine - pharmacology | Calcium Signaling - drug effects | Cell Communication - drug effects | In Vitro Techniques | Dose-Response Relationship, Radiation | Index Medicus | Cellular | neuronglia interaction | Molecular
Journal Article
Journal of Cardiovascular Pharmacology, ISSN 0160-2446, 09/2004, Volume 44, Issue 3, pp. 302 - 309
The mechanisms involved in the cardioprotector effect of red wine have not yet been completely elucidated but probably an endothelium-dependent vasodilator... 
Antihypertensive | EDHF | Brazilian red wine | Vasodilation | Endothelium | Flavonoids - antagonists & inhibitors | Male | Nitroglycerin - pharmacology | Yohimbine - pharmacology | Glyburide - pharmacology | Charybdotoxin - pharmacology | Oxadiazoles - pharmacology | Phenols - antagonists & inhibitors | Brazil | Polyphenols | Wine - adverse effects | Muscle, Smooth, Vascular - drug effects | Phenols - pharmacology | Administration, Oral | Rats | Atropine - pharmacology | Pressure | Vasoconstriction - drug effects | Indomethacin - pharmacology | Phenols - analysis | Pyrilamine - pharmacology | Perfusion | Vasodilation - drug effects | Quinazolines - pharmacology | Bradykinin - analogs & derivatives | Norepinephrine - pharmacology | Flavonoids - analysis | Rats, Wistar | Nitric Oxide Synthase - antagonists & inhibitors | Mesenteric Arteries - drug effects | Guanylate Cyclase - antagonists & inhibitors | Apamin - pharmacology | Endothelium, Vascular - physiology | Quinoxalines - pharmacology | Hypertension - chemically induced | Potassium Chloride - pharmacology | Hypertension - prevention & control | Clonidine - pharmacology | Blood Pressure - drug effects | Flavonoids - pharmacology | Vasodilation - physiology | Drug Therapy, Combination | Oxadiazoles - chemistry | Quinazolines - chemistry | Bradykinin - pharmacology | Acetylcholine - pharmacology | NG-Nitroarginine Methyl Ester - adverse effects | Alcohol Drinking - adverse effects | Clonidine - antagonists & inhibitors | Animals | Deoxycholic Acid - pharmacology | Acetylcholine - antagonists & inhibitors | Index Medicus
Journal Article
Biological and Pharmaceutical Bulletin, ISSN 0918-6158, 2007, Volume 30, Issue 1, pp. 54 - 58
Solifenacin succinate [YM905; (3R)-1-azabicyclo[2.2.2]oct-3-yl(1S)-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate monosuccinate] is a new muscarinic... 
bladder capacity | solifenacin | urinary bladder | muscarinic receptor | Muscarinic receptor | Solifenacin | Urinary bladder | Bladder capacity | OVERACTIVE BLADDER SYNDROME | M-3 MUSCARINIC RECEPTORS | RAT | URINARY-BLADDER | DETRUSOR OVERACTIVITY | TOLTERODINE | SALIVARY-GLAND | IN-VITRO | DOUBLE-BLIND | PHARMACOLOGY & PHARMACY | MICE | Cricetulus | Rats, Wistar | Solifenacin Succinate | Benzofurans - pharmacology | Male | Phenylpropanolamine - pharmacology | Receptors, Muscarinic - metabolism | Muscarinic Antagonists - therapeutic use | Pyrrolidines - pharmacology | Dose-Response Relationship, Drug | Mandelic Acids - pharmacology | Muscle, Smooth - drug effects | Urinary Bladder, Overactive - drug therapy | Quinuclidines - therapeutic use | Receptors, Muscarinic - drug effects | Transfection | Muscarinic Antagonists - pharmacology | Tolterodine Tartrate | Urination - drug effects | Benzilates - pharmacology | Cholinergic Agonists - pharmacology | Cresols - pharmacology | CHO Cells | Muscarinic Antagonists - metabolism | Binding, Competitive | Tetrahydroisoquinolines - pharmacology | Cricetinae | Quinuclidines - pharmacology | Rats | Atropine - pharmacology | Tetrahydroisoquinolines - therapeutic use | Rats, Sprague-Dawley | Carbachol - pharmacology | Animals | Muscle Contraction - drug effects | Tetrahydroisoquinolines - metabolism | N-Methylscopolamine - metabolism | Urinary Bladder - drug effects | Benzhydryl Compounds - pharmacology | In Vitro Techniques | Quinuclidines - metabolism | Index Medicus
Journal Article