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1. Full Text Presynaptic α4β2 nicotinic acetylcholine receptors increase glutamate release and serotonin neuron excitability in the dorsal raphe nucleus
by Garduño, Julieta and Galindo-Charles, Luis and Jiménez-Rodríguez, Javier and Galarraga, Elvira and Tapia, Dagoberto and Mihailescu, Stefan and Hernandez-Lopez, Salvador
Journal of Neuroscience, ISSN 0270-6474, 10/2012, Volume 32, Issue 43, pp. 15148 - 15157
Several behavioral effects of nicotine are mediated by changes in serotonin (5-HT) release in brain areas that receive serotonergic afferents from the dorsal... 
Electric Stimulation | Rats, Wistar | Dihydro-beta-Erythroidine - pharmacology | Male | Nicotinic Antagonists - pharmacology | Raphe Nuclei - cytology | Excitatory Postsynaptic Potentials - drug effects | Nicotine - pharmacology | Excitatory Postsynaptic Potentials - physiology | Muscarinic Antagonists - pharmacology | Egtazic Acid - analogs & derivatives | 6-Cyano-7-nitroquinoxaline-2,3-dione - pharmacology | Indoles - pharmacology | Tetrodotoxin - pharmacology | Cadmium Chloride - pharmacology | Cholinergic Agonists - pharmacology | Ryanodine - pharmacology | Animals, Newborn | Serotonergic Neurons - physiology | Presynaptic Terminals - drug effects | Acetylcholine - pharmacology | Enzyme Inhibitors - pharmacology | Glutamic Acid - physiology | Rats | Atropine - pharmacology | Sodium Channel Blockers - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Presynaptic Terminals - physiology | Aconitine - analogs & derivatives | Bicuculline - pharmacology | Chelating Agents - pharmacology | Aconitine - pharmacology | GABA Antagonists - pharmacology | Physostigmine - pharmacology | Patch-Clamp Techniques | Animals | Egtazic Acid - pharmacology | Receptors, Nicotinic - physiology | Nicotine - analogs & derivatives | Serotonin - metabolism | In Vitro Techniques | Serotonergic Neurons - cytology | Index Medicus
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2. Full Text Signal Transduction Underlying the Inhibitory Mechanism of Fluoxetine on Electrical Field Stimulation Response in Rat Ileal Smooth Muscle
by Khin, Phyu Phyu and Zaw, Tin Sandar and Sohn, Uy Dong
Pharmacology, ISSN 0031-7012, 03/2017, Volume 99, Issue 5-6, pp. 216 - 225
Fluoxetine (FLX), a well-known antidepressant drug under the class of selective serotonin reuptake inhibitor, exerts its action by inhibiting the reuptake of... 
Relaxation | Rat's ileum smooth muscle | Electrical field stimulation | Fluoxetine | PHARMACOLOGICAL CHARACTERIZATION | ISOLATED ILEUM | NERVE-STIMULATION | SEROTONIN REUPTAKE INHIBITOR | NITRIC-OXIDE | PHARMACOLOGY & PHARMACY | GASTROINTESTINAL MOTILITY | ION CHANNELS | IRRITABLE-BOWEL-SYNDROME | ISOLATED GUINEA-PIG | K+ CHANNELS | Tetraethylammonium - pharmacology | Ondansetron - pharmacology | Electric Stimulation | Male | Muscle, Smooth - drug effects | Ileum - drug effects | Drug Interactions | Glyburide - pharmacology | Estrenes - pharmacology | Pyrrolidinones - pharmacology | Indoles - pharmacology | Muscle, Smooth - physiology | 4-Aminopyridine - pharmacology | Amides - pharmacology | NG-Nitroarginine Methyl Ester - pharmacology | Fluoxetine - pharmacology | Rats | Atropine - pharmacology | Bicuculline - pharmacology | Sulfonamides - pharmacology | Calcimycin - pharmacology | Benzophenanthridines - pharmacology | Fluoxetine - antagonists & inhibitors | Azepines - pharmacology | Animals | Signal Transduction - drug effects | Muscle Contraction - drug effects | Muscle Contraction - physiology | Ileum - physiology | Pyridines - pharmacology | In Vitro Techniques | Index Medicus
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3. Full Text Role of Ca2+ Ions in Nicotinic Facilitation of GABA Release in Mouse Thalamus
by Lena, Clement and Changeux, Jean-Pierre
Journal of Neuroscience, ISSN 0270-6474, 01/1997, Volume 17, Issue 2, pp. 576 - 585
Presynaptic nicotinic acetylcholine receptors (nAChRs) are present in many regions of the brain and potentially serve as targets for the pharmacological action... 
GABA | calcium | facilitation | thalamus (sensory nuclei) | nicotinic acetylcholine receptors | presynaptic | ADRENAL CHROMAFFIN CELLS | INTERPEDUNCULAR NUCLEUS | FROG NEUROMUSCULAR-JUNCTION | OPTIC-NERVE TERMINALS | RAT CENTRAL NEURONS | NEUROSCIENCES | LATERAL GENICULATE-NUCLEUS | ACETYLCHOLINE-RECEPTORS | SUBUNIT MESSENGER-RNAS | CHOLINERGIC RECEPTORS | EXCITATORY SYNAPTIC TRANSMISSION | Thalamic Nuclei - metabolism | Dihydro-beta-Erythroidine - pharmacology | Lobeline - pharmacology | Nicotinic Antagonists - pharmacology | Pyridazines - pharmacology | Cations, Divalent - pharmacology | Nicotine - pharmacology | Quinolizines | Calcium Channels - physiology | Calcium - physiology | Receptors, Nicotinic - chemistry | Receptors, GABA-A - drug effects | 6-Cyano-7-nitroquinoxaline-2,3-dione - pharmacology | Receptors, Nicotinic - deficiency | Dimethylphenylpiperazinium Iodide - pharmacology | Ion Transport | gamma-Aminobutyric Acid - secretion | Tetrodotoxin - pharmacology | Action Potentials - drug effects | Nicotinic Agonists - pharmacology | Microcystins | Alkaloids - pharmacology | Mice, Inbred C57BL | Atropine - pharmacology | Aconitine - analogs & derivatives | Marine Toxins - pharmacology | Aconitine - pharmacology | Calcium Channel Blockers - pharmacology | Potassium - pharmacology | Neurons, Afferent - physiology | GABA Antagonists - pharmacology | Mice, Knockout | Carbachol - pharmacology | Arousal - physiology | Bridged Bicyclo Compounds, Heterocyclic - pharmacology | Patch-Clamp Techniques | Animals | Azocines | Receptors, Nicotinic - physiology | Bacterial Toxins - pharmacology | Thalamic Nuclei - secretion | Mice | Pyridines - pharmacology | Receptors, Nicotinic - genetics | Index Medicus
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4. Full Text Effect of the mixed phosphodiesterase 3/4 inhibitor RPL554 on human isolated bronchial smooth muscle tone
by Calzetta, Luigino and Page, Clive P and Spina, Domenico and Cazzola, Mario and Rogliani, Paola and Facciolo, Francesco and Matera, Maria Gabriella
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 09/2013, Volume 346, Issue 3, pp. 414 - 423
The phosphodiesterase (PDE) enzyme family hydrolyzes cAMP and cGMP, second messengers that regulate a variety of cellular processes, including airway smooth... 
ANTIASTHMA DRUGS | CELLS | OBSTRUCTIVE PULMONARY-DISEASE | IN-VITRO | BRAIN NATRIURETIC PEPTIDE | PHARMACOLOGY & PHARMACY | HUMAN AIRWAYS | ASTHMATIC-PATIENTS | IDENTIFICATION | EXPRESSION | AGONIST | Electric Stimulation | Albuterol - pharmacology | Phosphodiesterase 3 Inhibitors - pharmacology | Humans | Middle Aged | Adrenergic beta-Agonists - pharmacology | Atropine - pharmacology | Male | Muscle Tonus - drug effects | Phosphodiesterase 4 Inhibitors - pharmacology | Bronchi - drug effects | Drug Synergism | Muscle, Smooth - drug effects | Isoquinolines - pharmacology | Muscarinic Antagonists - pharmacology | Muscle Contraction - drug effects | Female | Glycopyrrolate - pharmacology | Pyrimidinones - pharmacology | In Vitro Techniques | Index Medicus
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5. Full Text Urothelial/Lamina Propria Spontaneous Activity and the Role of M3 Muscarinic Receptors in Mediating Rate Responses to Stretch and Carbachol
by Moro, Christian and Uchiyama, Jumpei and Chess-Williams, Russ
Urology, ISSN 0090-4295, 2011, Volume 78, Issue 6, pp. 1442.e9 - 1442.e15
Objective To investigate the effects of tissue stretch and muscarinic receptor stimulation on the spontaneous activity of the urothelium/lamina propria and... 
Urology | SUBUROTHELIAL MYOFIBROBLASTS | DETRUSOR | OVERACTIVE BLADDER | MUSCARINIC RECEPTOR SUBTYPES | CONTRACTION | URINARY-BLADDER | UROTHELIUM | UROLOGY & NEPHROLOGY | MUSCLE IN-VITRO | PIG BLADDER | RELEASE | Urothelium - metabolism | Solifenacin Succinate | Stress, Mechanical | Benzofurans - pharmacology | Phenylpropanolamine - pharmacology | Pyrrolidines - pharmacology | Mandelic Acids - pharmacology | Piperidines - pharmacology | Muscarinic Antagonists - pharmacology | Swine | Tolterodine Tartrate | Mucous Membrane - drug effects | Pirenzepine - pharmacology | Cresols - pharmacology | Tetrahydroisoquinolines - pharmacology | Urinary Bladder - metabolism | Quinuclidines - pharmacology | Receptor, Muscarinic M3 - metabolism | Atropine - pharmacology | Mucous Membrane - metabolism | Carbachol - pharmacology | Animals | Muscle Contraction - drug effects | Diamines - pharmacology | Urinary Bladder - drug effects | Benzhydryl Compounds - pharmacology | Urothelium - drug effects | Universities and colleges | Carbachol | Cardiotonic agents | Cardiac glycosides | Index Medicus
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6. Full Text Piperine decreases pilocarpine-induced convulsions by GABAergic mechanisms
by da Cruz, Giovany Michely Pinto and Felipe, Cícero Francisco Bezerra and Scorza, Fúlvio Alexandre and da Costa, Marta Aline Coelho and Tavares, Alinne Farias and Menezes, Maria Luiza Feitosa and de Andrade, Geanne Matos and Leal, Luzia Kalyne A.M and Brito, Gerly Anne C and da Graça Naffah-Mazzacoratti, Maria and Cavalheiro, Esper Abrão and de Barros Viana, Glauce Socorro
Pharmacology, Biochemistry and Behavior, ISSN 0091-3057, 03/2013, Volume 104, Issue 1, pp. 144 - 153
Piperine, an alkaloid present in the genus, was shown to have an anticonvulsant activity, evaluated by the pilocarpine-induced model, in mice. Pilocarpine (350... 
Amino acids | Piperine | Pilocarpine-induced convulsions | Antioxidant and anti-inflammatory effects | Monoamines | OXIDATIVE STRESS | HIGH-FAT DIET | DOPAMINERGIC RECEPTORS | GATED CALCIUM-CHANNELS | NEUROSCIENCES | SEIZURE ACTIVITY | IN-VITRO | MUSCARINIC RECEPTOR SUBTYPES | BRAIN INFLAMMATION | BLACK PEPPER | BEHAVIORAL SCIENCES | PHARMACOLOGY & PHARMACY | INDUCED STATUS EPILEPTICUS | Tumor Necrosis Factor-alpha - metabolism | Humans | Seizures - drug therapy | Nitrites - metabolism | Male | Pilocarpine - toxicity | Epilepsy - physiopathology | Nimodipine - pharmacology | Anticonvulsants - pharmacology | Diazepam - pharmacology | Seizures - chemically induced | gamma-Aminobutyric Acid - physiology | Amino Acids - metabolism | Flumazenil - pharmacology | Seizures - physiopathology | Piperidines - pharmacology | Disease Models, Animal | Memantine - pharmacology | Alkaloids - pharmacology | Brain - physiopathology | Atropine - pharmacology | Antioxidants - pharmacology | Brain - drug effects | Animals | Polyunsaturated Alkamides - pharmacology | Epilepsy - drug therapy | Mice | Biogenic Monoamines - metabolism | Benzodioxoles - pharmacology | Antioxidants | Calcium channels | Analysis | GABA | Convulsions | Glutamate | Index Medicus
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7. Full Text INCREASE OF INSULIN SECRETION BY GINSENOSIDE RH2 TO LOWER PLASMA GLUCOSE IN WISTAR RATS
by Lee, Wen-Kung and Kao, Shung-Te and Liu, I-Min and Cheng, Juei-Tang
Clinical and Experimental Pharmacology and Physiology, ISSN 0305-1870, 01/2006, Volume 33, Issue 1, pp. 27 - 32
SUMMARY • The aim of the present study was to clarify the role of ginsenoside Rh2 as the active compound in Panax ginseng root for lowering plasma glucose in... 
Wistar rats | ginsenosides Rh2 | acetylcholine | insulin | muscarinic M3 receptors | 3 | receptors | muscarinic M | Muscarinic M | Acetylcholine | Ginsenosides Rh2 | Insulin | CELLS | PHYSIOLOGY | STIMULATION | PANAX-GINSENG | PERFORMANCE | RELEASE | MUSCARINIC ACETYLCHOLINE-RECEPTOR | INTESTINAL BACTERIA | PHARMACOKINETICS | HYPOGLYCEMIC ACTIVITY | PHARMACOLOGY & PHARMACY | MICE | muscarinic M-3 receptors | Injections, Intravenous | C-Peptide - blood | Enzyme-Linked Immunosorbent Assay | Rats, Wistar | Cholinergic Agents - pharmacology | Drugs, Chinese Herbal - pharmacology | Rats | Atropine - pharmacology | Male | Ginsenosides - pharmacology | Insulin - blood | Dose-Response Relationship, Drug | Insulin - metabolism | Animals | Piperidines - pharmacology | Hemicholinium 3 - pharmacology | Muscarinic Antagonists - pharmacology | Ginsenosides - administration & dosage | Blood Glucose - metabolism | Insulin Secretion | Neuromuscular Depolarizing Agents - pharmacology | Ginsenosides, administration and dosage | Atropine, pharmacology | Insulin, secretion | Insulin, blood | C-Peptide, blood | Blood Glucose, metabolism | Hemicholinium 3, pharmacology | Piperidines, pharmacology | Cholinergic Agents, pharmacology | Drugs, Chinese Herbal, pharmacology | Muscarinic Antagonists, pharmacology | Neuromuscular Depolarizing Agents, pharmacology | Ginsenosides, pharmacology | Index Medicus
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8. Full Text Relief of hypersensitivity after nerve injury from systemic donepezil involves spinal cholinergic and γ-aminobutyric acid mechanisms
by Kimura, Masafumi and Hayashida, Ken-Ichiro and Eisenach, James C and Saito, Shigeru and Obata, Hideaki
Anesthesiology, ISSN 0003-3022, 01/2013, Volume 118, Issue 1, pp. 173 - 180
Background: Evoking spinal release of acetylcholine (ACh) produces antinociception in normal animals and reduces hypersensitivity after nerve injury, and some... 
DORSAL-HORN NEURONS | NEUROPATHIC PAIN | GABA-IMMUNOREACTIVITY | NICOTINIC RECEPTORS | NORADRENALINE REUPTAKE INHIBITOR | TACTILE ALLODYNIA | SUBSTANTIA-GELATINOSA | PERIPHERAL NEUROPATHY | ANESTHESIOLOGY | INTRATHECALLY ADMINISTERED MILNACIPRAN | SELECTIVE LOSS | Cholinergic Agents - pharmacology | Male | Nicotinic Antagonists - pharmacology | Piperidines - pharmacology | Mecamylamine - pharmacology | Spinal Nerves - drug effects | Organophosphorus Compounds - pharmacology | Cholinergic Agents - blood | Disease Models, Animal | GABA-A Receptor Antagonists - pharmacology | Rats | gamma-Aminobutyric Acid - pharmacology | Atropine - pharmacology | Bicuculline - pharmacology | Parasympatholytics - pharmacology | Rats, Sprague-Dawley | Neuralgia - drug therapy | GABA Antagonists - pharmacology | GABA Agents - pharmacology | gamma-Aminobutyric Acid - blood | Animals | Cholinesterase Inhibitors - pharmacology | GABA Agents - blood | Indans - pharmacology | Peripheral Nerve Injuries | Index Medicus | Abridged Index Medicus
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9. Full Text Nicotine-Mediated Activation of Dopaminergic Neurons in Distinct Regions of the Ventral Tegmental Area
by Zhao-Shea, Rubing and Liu, Liwang and Soll, Lindsey G and Improgo, Ma Reina and Meyers, Erin E and McIntosh, J. Michael and Grady, Sharon R and Marks, Michael J and Gardner, Paul D and Tapper, Andrew R
Neuropsychopharmacology, ISSN 0893-133X, 04/2011, Volume 36, Issue 5, pp. 1021 - 1032
Nicotine activation of nicotinic acetylcholine receptors (nAChRs) within the dopaminergic (DAergic) neuron-rich ventral tegmental area (VTA) is necessary and... 
nicotine | acetylcholine | ventral tegmental area | dopamine | mice | smoking | PSYCHIATRY | REWARD | NEUROSCIENCES | NUCLEUS-ACCUMBENS | POSTERIOR | ACETYLCHOLINE-RECEPTORS | CIGARETTE-SMOKING | MUTANT MICE | SYNAPTIC MECHANISMS | ETHANOL | PHARMACOLOGY & PHARMACY | ALPHA-CONOTOXIN-MII | MIDBRAIN | Tyrosine 3-Monooxygenase - metabolism | Temperature | Male | Nicotinic Antagonists - pharmacology | Ventral Tegmental Area - cytology | RNA, Messenger - metabolism | Patch-Clamp Techniques - methods | Nicotine - pharmacology | Drug Interactions | Muscarinic Antagonists - pharmacology | Mecamylamine - pharmacology | 6-Cyano-7-nitroquinoxaline-2,3-dione - pharmacology | Receptors, Nicotinic - deficiency | Neurons - metabolism | Neurons - drug effects | Electric Stimulation - methods | Action Potentials - drug effects | Dopamine - metabolism | Nicotinic Agonists - pharmacology | GABA-A Receptor Antagonists - pharmacology | Receptors, Nicotinic - metabolism | Gene Expression Regulation - genetics | Cell Size - drug effects | Mice, Inbred C57BL | Proto-Oncogene Proteins c-fos - metabolism | Atropine - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Bicuculline - pharmacology | Mice, Knockout | Gene Expression Regulation - drug effects | Microdissection - methods | Animals | Cell Count - methods | Analysis of Variance | Mice | In Vitro Techniques | Receptors, Nicotinic - genetics | Index Medicus | addiction & substance abuse | neurophysiology | Original
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10. Full Text Zebrafish heart as a model to study the integrative autonomic control of pacemaker function
by Stoyek, Matthew R and Quinn, T. Alexander and Croll, Roger P and Smith, Frank M
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 09/2016, Volume 311, Issue 3, pp. H676 - H688
The cardiac pacemaker sets the heart's primary rate, with pacemaker discharge controlled by the autonomic nervous system through intra-cardiac ganglia. A... 
Intracardiac nervous system | Parasympathetic | Atrioventricular node | Sinoatrial node | Sympathetic | DANIO-RERIO | NERVOUS-SYSTEM | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | intracardiac nervous system | CONDUCTION SYSTEM | sympathetic | MUSCARINIC RECEPTORS | POSTGANGLIONIC NEURONS | sinoatrial node | ADULT ZEBRAFISH | ADRENERGIC-RECEPTORS | NUCLEUS AMBIGUUS | parasympathetic | VAGAL PREGANGLIONIC NEURONS | atrioventricular node | PERIPHERAL VASCULAR DISEASE | Muscarinic Agonists - pharmacology | Sympathetic Nervous System - drug effects | Heart - physiology | Sympathomimetics - pharmacology | Nicotinic Antagonists - pharmacology | Sinoatrial Node - drug effects | Atrioventricular Node - physiology | Atrioventricular Node - drug effects | Nicotine - pharmacology | Vagus Nerve Stimulation | Adrenergic beta-Antagonists - pharmacology | Hexamethonium - pharmacology | Sympathetic Nervous System - physiology | Muscarinic Antagonists - pharmacology | Electrocardiography | Models, Animal | Parasympathetic Nervous System - physiology | Nicotinic Agonists - pharmacology | Heart - innervation | Heart - physiopathology | Heart Rate | Receptor, Muscarinic M2 - metabolism | Autonomic Nervous System - drug effects | Isolated Heart Preparation | Sinoatrial Node - physiology | Autonomic Nervous System - physiology | Sinoatrial Node - physiopathology | Bradycardia - physiopathology | Atropine - pharmacology | Timolol - pharmacology | Zebrafish | Atrioventricular Node - innervation | Sinoatrial Node - innervation | Tachycardia - physiopathology | Receptors, Adrenergic, beta-2 - metabolism | Animals | Isoproterenol - pharmacology | Parasympathetic Nervous System - drug effects | Heart - drug effects | Muscarine - pharmacology | Atrioventricular Node - physiopathology | Health aspects | Pacemaker, Artificial (Heart) | Heart beat | Heart rate | Nervous system | Neurons | Cells | Index Medicus | Integrative Cardiovascular Physiology and Pathophysiology
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11. Full Text Nicotine recruits a local glutamatergic circuit to excite septohippocampal GABAergic neurons
by Wu, Min and Hajszan, Tibor and Leranth, Csaba and Alreja, Meenakshi
European Journal of Neuroscience, ISSN 0953-816X, 09/2003, Volume 18, Issue 5, pp. 1155 - 1168
Tonic impulse flow in the septohippocampal GABAergic pathway is essential for normal cognitive functioning and is sustained, in part, by acetylcholine (ACh)... 
Learning and memory | Septum | Metabotropic | Cognition | Theta rhythm | Glutamate | DIAGONAL BAND COMPLEX | PARVALBUMIN | CA1 INTERNEURONS | cognition | ALZHEIMERS-DISEASE | IMPULSE FLOW | metabotropic | NEUROSCIENCES | septum | theta rhythm | ACETYLCHOLINE-RECEPTORS | learning and memory | MEDIAL SEPTAL AREA | CENTRAL-NERVOUS-SYSTEM | BASAL FOREBRAIN | RAT HIPPOCAMPUS | glutamate | Muscarinic Agonists - pharmacology | gamma-Aminobutyric Acid - metabolism | Cell Count | Septum of Brain - physiology | Parvalbumins - metabolism | Male | Nicotinic Antagonists - pharmacology | Drug Interactions | Neuroprotective Agents - pharmacology | Septum of Brain - ultrastructure | Vesicular Glutamate Transport Protein 2 | Muscarinic Antagonists - pharmacology | Hippocampus - ultrastructure | Tetrodotoxin - pharmacology | Chromones - pharmacology | Animals, Newborn | Membrane Potentials - drug effects | Drug Administration Routes | Acyclovir - pharmacology | Rats | Atropine - pharmacology | Synapses - ultrastructure | Excitatory Amino Acid Antagonists - pharmacology | Bicuculline - pharmacology | Rats, Sprague-Dawley | GABA Antagonists - pharmacology | Immunohistochemistry - methods | Glycine - pharmacology | Microscopy, Electron - methods | Muscarine - pharmacology | Glycine - analogs & derivatives | Electric Conductivity | Excitatory Postsynaptic Potentials - drug effects | Patch-Clamp Techniques - methods | Nicotine - pharmacology | Dose-Response Relationship, Drug | Resorcinols - pharmacology | Cycloleucine - pharmacology | Tubocurarine - pharmacology | Synapses - metabolism | Neurons - physiology | 6-Cyano-7-nitroquinoxaline-2,3-dione - pharmacology | Neurons - drug effects | Nicotinic Agonists - pharmacology | Vesicular Transport Proteins | Acyclovir - analogs & derivatives | Valine - analogs & derivatives | Aconitine - analogs & derivatives | Aconitine - pharmacology | Hippocampus - cytology | Membrane Potentials - physiology | Animals | Carrier Proteins - metabolism | Membrane Transport Proteins | Choline - pharmacology | Microscopy, Electron - instrumentation | Valine - pharmacology | In Vitro Techniques | Cycloleucine - analogs & derivatives | Bungarotoxins - pharmacology | Index Medicus
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12. Full Text Properties of Synaptically Evoked Astrocyte Calcium Signal Reveal Synaptic Information Processing by Astrocytes
by Perea, Gertrudis and Araque, Alfonso
Journal of Neuroscience, ISSN 0270-6474, 03/2005, Volume 25, Issue 9, pp. 2192 - 2203
The synaptic control of the astrocytic intracellular Ca (2+) is crucial in the reciprocal astrocyte - neuron communication. Using electrophysiological and Ca... 
Neurotransmitter release | Neuron-glia interaction | Intracellular calcium | Glutamate | Astrocytes | Synaptic activity | NEURONAL-ACTIVITY | ACTIVATION | synaptic activity | GLIAL-CELLS | neurotransmitter release | NEUROSCIENCES | DEPENDENT GLUTAMATE RELEASE | POTENTIATION | intracellular calcium | astrocytes | neuron-glia interaction | OSCILLATIONS | glutamate | IN-SITU | MODULATION | COMMUNICATION | Glycine - analogs & derivatives | Excitatory Postsynaptic Potentials - radiation effects | Synaptic Transmission - physiology | Rats, Wistar | Aniline Compounds - metabolism | Calcium - metabolism | Calcium Signaling - physiology | Cell Communication - physiology | Neurons - cytology | Glial Fibrillary Acidic Protein - metabolism | Excitatory Postsynaptic Potentials - drug effects | Patch-Clamp Techniques - methods | Diagnostic Imaging - methods | Excitatory Postsynaptic Potentials - physiology | Drug Interactions | Xanthenes - metabolism | Muscarinic Antagonists - pharmacology | Neurons - physiology | 6-Cyano-7-nitroquinoxaline-2,3-dione - pharmacology | Synaptic Transmission - drug effects | Tetrodotoxin - pharmacology | Electric Stimulation - methods | 4-Aminopyridine - pharmacology | Potassium Channel Blockers - pharmacology | Animals, Newborn | Astrocytes - cytology | Synapses - drug effects | Glutamic Acid - pharmacology | Acetylcholine - pharmacology | Synapses - physiology | Rats | Atropine - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Hippocampus - cytology | Immunohistochemistry - methods | Astrocytes - physiology | Animals | Glycine - pharmacology | Calcium Signaling - drug effects | Cell Communication - drug effects | In Vitro Techniques | Dose-Response Relationship, Radiation | Index Medicus | Cellular | neuronglia interaction | Molecular
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13. Full Text Mechanism of the Endothelium-Dependent Vasodilation and the Antihypertensive Effect of Brazilian Red wine
by Soares de Moura, Roberto and Miranda, Daniel Z and Pinto, Ana Cláudia A and Sicca, Raquel F and Souza, Marcelo A. V and Rubenich, Lorna M. S and Carvalho, Lenize C. R. M and Rangel, Bruno M and Tano, Tania and Madeira, Socorro V. F and Resende, Ângela C
Journal of Cardiovascular Pharmacology, ISSN 0160-2446, 09/2004, Volume 44, Issue 3, pp. 302 - 309
The mechanisms involved in the cardioprotector effect of red wine have not yet been completely elucidated but probably an endothelium-dependent vasodilator... 
Antihypertensive | EDHF | Brazilian red wine | Vasodilation | Endothelium | Flavonoids - antagonists & inhibitors | Male | Nitroglycerin - pharmacology | Yohimbine - pharmacology | Glyburide - pharmacology | Charybdotoxin - pharmacology | Oxadiazoles - pharmacology | Phenols - antagonists & inhibitors | Brazil | Polyphenols | Wine - adverse effects | Muscle, Smooth, Vascular - drug effects | Phenols - pharmacology | Administration, Oral | Rats | Atropine - pharmacology | Pressure | Vasoconstriction - drug effects | Indomethacin - pharmacology | Phenols - analysis | Pyrilamine - pharmacology | Perfusion | Vasodilation - drug effects | Quinazolines - pharmacology | Bradykinin - analogs & derivatives | Norepinephrine - pharmacology | Flavonoids - analysis | Rats, Wistar | Nitric Oxide Synthase - antagonists & inhibitors | Mesenteric Arteries - drug effects | Guanylate Cyclase - antagonists & inhibitors | Apamin - pharmacology | Endothelium, Vascular - physiology | Quinoxalines - pharmacology | Hypertension - chemically induced | Potassium Chloride - pharmacology | Hypertension - prevention & control | Clonidine - pharmacology | Blood Pressure - drug effects | Flavonoids - pharmacology | Vasodilation - physiology | Drug Therapy, Combination | Oxadiazoles - chemistry | Quinazolines - chemistry | Bradykinin - pharmacology | Acetylcholine - pharmacology | NG-Nitroarginine Methyl Ester - adverse effects | Alcohol Drinking - adverse effects | Clonidine - antagonists & inhibitors | Animals | Deoxycholic Acid - pharmacology | Acetylcholine - antagonists & inhibitors | Index Medicus
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14. Full Text Pharmacological Characterization of a New Antimuscarinic Agent, Solifenacin Succinate, in Comparison with Other Antimuscarinic Agents
by Ohtake, Akiyoshi and Saitoh, Chikashi and Yuyama, Hironori and Ukai, Masashi and Okutsu, Hiroko and Noguchi, Yukiko and Hatanaka, Toshiki and Suzuki, Masanori and Sato, Shuichi and Sasamata, Masao and Miyata, Keiji
Biological and Pharmaceutical Bulletin, ISSN 0918-6158, 2007, Volume 30, Issue 1, pp. 54 - 58
Solifenacin succinate [YM905; (3R)-1-azabicyclo[2.2.2]oct-3-yl(1S)-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate monosuccinate] is a new muscarinic... 
bladder capacity | solifenacin | urinary bladder | muscarinic receptor | Muscarinic receptor | Solifenacin | Urinary bladder | Bladder capacity | OVERACTIVE BLADDER SYNDROME | M-3 MUSCARINIC RECEPTORS | RAT | URINARY-BLADDER | DETRUSOR OVERACTIVITY | TOLTERODINE | SALIVARY-GLAND | IN-VITRO | DOUBLE-BLIND | PHARMACOLOGY & PHARMACY | MICE | Cricetulus | Rats, Wistar | Solifenacin Succinate | Benzofurans - pharmacology | Male | Phenylpropanolamine - pharmacology | Receptors, Muscarinic - metabolism | Muscarinic Antagonists - therapeutic use | Pyrrolidines - pharmacology | Dose-Response Relationship, Drug | Mandelic Acids - pharmacology | Muscle, Smooth - drug effects | Urinary Bladder, Overactive - drug therapy | Quinuclidines - therapeutic use | Receptors, Muscarinic - drug effects | Transfection | Muscarinic Antagonists - pharmacology | Tolterodine Tartrate | Urination - drug effects | Benzilates - pharmacology | Cholinergic Agonists - pharmacology | Cresols - pharmacology | CHO Cells | Muscarinic Antagonists - metabolism | Binding, Competitive | Tetrahydroisoquinolines - pharmacology | Cricetinae | Quinuclidines - pharmacology | Rats | Atropine - pharmacology | Tetrahydroisoquinolines - therapeutic use | Rats, Sprague-Dawley | Carbachol - pharmacology | Animals | Muscle Contraction - drug effects | Tetrahydroisoquinolines - metabolism | N-Methylscopolamine - metabolism | Urinary Bladder - drug effects | Benzhydryl Compounds - pharmacology | In Vitro Techniques | Quinuclidines - metabolism | Index Medicus
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